XOMA Royalty Reports First Quarter 2025 Financial Results and Highlights Business Achievements
- Net income of $2.4 million in Q1 2025, compared to $8.6 million loss in Q1 2024
- Strong cash position of $95.0 million as of March 31, 2025
- Significant revenue growth with total income of $15.9 million, up from $1.5 million YoY
- Robust cash receipts of $18.0 million including $13.4 million in royalties
- Multiple milestone achievements and pipeline advancements across portfolio companies
- G&A expenses remain high at $8.1 million despite slight decrease
- Increase in R&D expenses to $1.3 million from $33,000 in Q1 2024
- Decrease in cash position from $106.4 million in December 2024 to $95.0 million
Insights
XOMA's Q1 results show positive momentum with $15.9M revenue, expanding royalty portfolio, and pipeline progression across multiple partners.
XOMA Royalty's Q1 2025 results demonstrate encouraging financial progress and portfolio expansion, strengthening its position as a royalty aggregator. The company reported
Cash receipts totaled
The portfolio continues to expand strategically. XOMA acquired an economic interest in Castle Creek's D-Fi (FCX-007), a Phase 3 gene therapy for dystrophic epidermolysis bullosa with multiple FDA designations (Orphan Drug, Rare Pediatric Disease, Fast Track, and RMAT). This
XOMA's existing portfolio is progressing well across multiple partners. Day One/Ipsen's tovorafenib MAA was accepted by EMA for pediatric low-grade glioma, triggering a
While G&A expenses remain substantial at
The multiple clinical and regulatory catalysts anticipated throughout 2025 (EMA decision on tovorafenib, Phase 3 data for ersodetug, Sildenafil Cream commercialization) could trigger additional milestone payments and eventually royalty streams, further strengthening XOMA's financial position on its path to consistent positive cash flow.
Pipeline advancements: The Marketing Authorization Application (MAA) for Day One Biopharmaceuticals and Ipsen’s tovorafenib was accepted for review by the European Marketing Authority (EMA) and Takeda initiated its Phase 3 trial exploring mezagitamab for the treatment of chronic primary immune thrombocytopenia
Business development: Acquired an economic interest in Castle Creek Biosciences’ D-Fi (FCX-007) through participation in a syndicated royalty financing transaction and successfully sold all unpartnered Kinnate assets
Cash receipts: Received
EMERYVILLE, Calif. , May 13, 2025 (GLOBE NEWSWIRE) -- XOMA Royalty Corporation (NASDAQ: XOMA), the biotech royalty aggregator, reported its first quarter 2025 financial results and highlighted recent actions that have the potential to deliver shareholder value.
“We are committed to generating value for shareholders through prudent cash deployment, strict expense control, and opportunistic share repurchases. Our first quarter highlights included the progression of key pipeline assets, solid cash receipts, and an increase in our share repurchase activity,” stated Owen Hughes, Chief Executive Officer of XOMA Royalty. “With accelerating royalty receipts and a robust pipeline, we believe a path to sustained cashflow generation is tangible.”
Royalty and Milestone Acquisitions
Partner | Asset and Transaction Detail |
Castle Creek | XOMA Royalty added a royalty interest in D-Fi (FCX-007), a Phase 3 asset being developed by Castle Creek Biosciences, to the portfolio. D-Fi is being studied in dystrophic epidermolysis bullosa (DEB), a rare progressive and debilitating skin disorder. D-Fi has been granted Orphan Drug Designation for the treatment of DEB, as well as Rare Pediatric Disease, Fast Track, and Regenerative Medicine Advanced Therapy designations by the FDA. XOMA Royalty contributed |
Partner Updates through May 9, 2025
Partner | Event |
Rezolute | In January, Rezolute received Breakthrough Therapy Designation from FDA for ersodetug (RZ358) for the treatment of hypoglycemia due to congenital hyperinsulinism (cHI)1. In February, the company announced the Independent Data Monitoring Committee (DMC) reviewed the safety data from eight infants ages 3 months to 1 year enrolled in the open-label portion of the sunRIZE Phase 3 study of ersodetug for the treatment of hypoglycemia due to cHI. Their conclusion was the safety profile was such that infants may now be enrolled in the double-blind, placebo-controlled study2. In April, Rezolute announced the Independent DMC recommended the sunRIZE Phase 3 trial continue as planned with no need to increase sample size. Enrollment is on track and is expected to be completed in May 2025. Topline data is anticipated in December 2025.3 In May, the company announced the FDA has granted Breakthrough Therapy Designation (BTD) to its investigational therapy, ersodetug, for the treatment of hypoglycemia caused by tumor HI.4 |
Affitech Research AS | XOMA Royalty paid |
Daré Bioscience | Announced its intention to make its Sildenafil Cream, |
Day One Biopharmaceuticals | Ipsen, Day One’s partner outside of the U.S., filed a Marketing Authorization Application (MMA) with the European Medicines Agency for tovorafenib as a treatment for pediatric low-grade glioma (pLGG)5. XOMA Royalty earned a |
Takeda | The first patient was dosed in Takeda’s Phase 3 clinical trial investigating mezagitamab as a treatment for adults with chronic primary immune thrombocytopenia (ITP). This achievement triggered a |
Partner | Event |
Kinnate | In early 2025, XOMA Royalty sold the five unpartnered Kinnate assets to several parties. Per the terms of the acquisition, a portion of any upfront payments received by XOMA Royalty will be distributed to the Kinnate CVR holders. |
Anticipated 2025 Events of Note
Partner | Event |
Day One Biopharmaceuticals | The European Medicines Agency (EMA) decision regarding Day One’s Marketing Authorization Application (MAA) for tovorafenib, a treatment for the most common childhood brain tumor, pediatric low-grade glioma (pLGG). |
Rezolute | Completion of enrollment in sunRIZE Phase 3 clinical trial, which is investigating ersodetug in infants and children with cHI. Topline data are expected in December 20253. First patient dosed in the Phase 3 registrational study for ersodetug for the treatment of hypoglycemia due to tumor hyperinsulinism6. |
Gossamer / Chiesi | Presentation of topline results from the Phase 3 PROSERA study, a global registrational clinical trial in patients with WHO Function Class II and III pulmonary arterial hypertension (PAH).7 Initiation of a registrational Phase 3 study in pulmonary hypertension associated with interstitial lung disease (PH-ILD) in 2025.1 |
Daré Bioscience | Successfully makes Sildenafil Cream available via prescription in the fourth quarter of 2025 as a compounded drug under Section 503B of the FDCA. Commencement of one of two registrational Phase 3 clinical trials investigating Sildenafil Cream, |
First Quarter 2025 Financial Results
Tom Burns, Chief Financial Officer of XOMA Royalty, commented, “In the first quarter, we received
Income and Revenue: XOMA Royalty recorded total income and revenues of
Research and Development (R&D) Expenses: R&D expenses were
General and Administrative (G&A) Expenses: G&A expenses were
In the quarter ended March 31, 2025, G&A expenses included
Interest Expense: Interest expense was
Amortization of Intangible Assets: Amortization of intangible assets relates to the IP acquired in the Company’s acquisition of Pulmokine in November 2024.
Other Income/Expense, net: The Company reported other expense, net, of
Net Income (Loss): Net income for the first quarter ended March 31, 2025, was
Cash: On March 31, 2025, XOMA Royalty had cash and cash equivalents of
About XOMA Royalty Corporation
XOMA Royalty is a biotechnology royalty aggregator playing a distinctive role in helping biotech companies achieve their goal of improving human health. XOMA Royalty acquires the potential future economics associated with pre-commercial and commercial therapeutic candidates that have been licensed to pharmaceutical or biotechnology companies. When XOMA Royalty acquires the future economics, the seller receives non-dilutive, non-recourse funding they can use to advance their internal drug candidate(s) or for general corporate purposes. The Company has an extensive and growing portfolio of assets (asset defined as the right to receive potential future economics associated with the advancement of an underlying therapeutic candidate). For more information about the Company and its portfolio, please visit www.xoma.com or follow XOMA Royalty Corporation on LinkedIn.
Forward-Looking Statements/Explanatory Notes
Certain statements contained in this press release are forward-looking statements within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934, including statements regarding the timing and amount of potential commercial payments to XOMA Royalty and other developments related to VABYSMO® (faricimab-svoa), OJEMDA™ (tovorafenib), MIPLYFFA™ (arimoclomol), XACIATO™ (clindamycin phosphate) vaginal gel
EXPLANATORY NOTE: Any references to “portfolio” in this press release refer strictly to milestone and/or royalty rights associated with a basket of drug products in development. Any references to “assets” in this press release refer strictly to milestone and/or royalty rights associated with individual drug products in development.
As of the date of this press release, the commercial assets in XOMA Royalty’s milestone and royalty portfolio are VABYSMO® (faricimab-svoa), OJEMDA™ (tovorafenib), MIPLYFFA™ (arimoclomol), XACIATO™ (clindamycin phosphate) vaginal gel
XOMA CORPORATION | |||||||
CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS | |||||||
(unaudited) | |||||||
(in thousands, except share and per share amounts) | |||||||
Three Months Ended March 31, | |||||||
2025 | 2024 | ||||||
Income and Revenues: | |||||||
Income from purchased receivables under the EIR method | $ | 6,070 | $ | - | |||
Income from purchased receivables under the cost recovery method | 5,525 | - | |||||
Revenue from contracts with customers | 4,000 | 1,000 | |||||
Revenue recognized under units-of-revenue method | 317 | 490 | |||||
Total income and revenues | 15,912 | 1,490 | |||||
Operating expenses: | |||||||
Research and development | 1,293 | 33 | |||||
General and administrative | 8,146 | 8,461 | |||||
Amortization of intangible assets | 544 | - | |||||
Total operating expenses | 9,983 | 8,494 | |||||
Income (Loss) from operations | 5,929 | (7,004 | ) | ||||
Other income (expense) | |||||||
Interest expense | (3,467 | ) | (3,551 | ) | |||
Other income (expense), net | (95 | ) | 1,960 | ||||
Net income (loss) | $ | 2,367 | $ | (8,595 | ) | ||
Net income (loss) available to (attributable to) common stockholders, basic | $ | 705 | $ | (9,963 | ) | ||
Basic net income (loss) per share available to (attributable to) common stockholders | $ | 0.06 | $ | (0.86 | ) | ||
Weighted average shares used in computing basic net income (loss) per share available to (attributable) to common stockholders | 11,969 | 11,580 | |||||
Net income (loss) available to (attributable to) common stockholders, diluted | $ | 999 | $ | (9,963 | ) | ||
Diluted net income (loss) per share available to (attributable to) common stockholders | $ | 0.06 | $ | (0.86 | ) | ||
Weighted average shares used in computing diluted net income (loss) per share available to (attributable) to common stockholders | 17,781 | 11,580 | |||||
XOMA CORPORATION | |||||||
CONDENSED CONSOLIDATED BALANCE SHEETS | |||||||
(in thousands, except share and per share amounts) | |||||||
March 31, | December 31, | ||||||
2025 | 2024 | ||||||
ASSETS | (unaudited) | ||||||
Current assets: | |||||||
Cash and cash equivalents | $ | 90,265 | $ | 101,654 | |||
Short-term restricted cash | 1,410 | 1,330 | |||||
Investment in equity securities | 2,382 | 3,529 | |||||
Trade and other receivables, net | 5,544 | 1,839 | |||||
Short-term royalty and commercial payment receivables under the EIR method | 12,240 | 14,763 | |||||
Short-term royalty and commercial payment receivables under the cost recovery method | 413 | 413 | |||||
Prepaid expenses and other current assets | 971 | 2,076 | |||||
Total current assets | 113,225 | 125,604 | |||||
Long-term restricted cash | 3,352 | 3,432 | |||||
Property and equipment, net | 29 | 32 | |||||
Operating lease right-of-use assets | 304 | 319 | |||||
Long-term royalty and commercial payment receivables under the EIR method | 4,857 | 4,970 | |||||
Long-term royalty and commercial payment receivables under the cost recovery method | 59,916 | 55,936 | |||||
Exarafenib milestone asset (Note 4) | 3,307 | 3,214 | |||||
Investment in warrants | 605 | - | |||||
Intangible assets, net | 25,365 | 25,909 | |||||
Other assets - long term | 1,790 | 1,861 | |||||
Total assets | $ | 212,750 | $ | 221,277 | |||
LIABILITIES AND STOCKHOLDERS’ EQUITY | |||||||
Current liabilities: | |||||||
Accounts payable | $ | 2,319 | $ | 1,053 | |||
Accrued and other liabilities | 1,221 | 5,752 | |||||
Contingent consideration under RPAs, AAAs, and CPPAs | - | 3,000 | |||||
Operating lease liabilities | 459 | 446 | |||||
Unearned revenue recognized under units-of-revenue method | 1,370 | 1,361 | |||||
Preferred stock dividend accrual | 1,368 | 1,368 | |||||
Current portion of long-term debt | 13,697 | 11,394 | |||||
Total current liabilities | 20,434 | 24,374 | |||||
Unearned revenue recognized under units-of-revenue method – long-term | 4,084 | 4,410 | |||||
Exarafenib milestone contingent consideration (Note 4) | 3,307 | 3,214 | |||||
Long-term operating lease liabilities | 362 | 483 | |||||
Long-term debt | 99,934 | 106,875 | |||||
Total liabilities | 128,121 | 139,356 | |||||
Stockholders’ equity: | |||||||
Preferred Stock, | |||||||
49 | 49 | ||||||
— | — | ||||||
Convertible preferred stock, 5,003 shares issued and outstanding as of March 31, 2025 and December 31, 2024 | — | — | |||||
Common stock, | 90 | 90 | |||||
Additional paid-in capital | 1,319,607 | 1,318,766 | |||||
Accumulated other comprehensive income | 118 | 73 | |||||
Accumulated deficit | (1,235,235 | ) | (1,237,057 | ) | |||
Total stockholders’ equity | 84,629 | 81,921 | |||||
Total liabilities and stockholders’ equity | $ | 212,750 | $ | 221,277 | |||
XOMA CORPORATION | |||||||
CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS | |||||||
(unaudited) | |||||||
(in thousands) | |||||||
Three Months Ended March 31, | |||||||
2025 | 2024 | ||||||
Cash flows from operating activities: | |||||||
Net income (loss) | $ | 2,367 | $ | (8,595 | ) | ||
Adjustments to reconcile net income (loss) to net cash provided by (used in) operating activities: | |||||||
Adjustment for income from EIR method purchased receivables | 1,743 | — | |||||
Stock-based compensation expense | 1,983 | 2,856 | |||||
Common stock contribution to 401(k) | 141 | 118 | |||||
Amortization of intangible assets | 544 | — | |||||
Depreciation | 3 | 2 | |||||
Accretion of long-term debt discount and debt issuance costs | 427 | 306 | |||||
Non-cash lease expense | 17 | 14 | |||||
Change in fair value of equity securities | 1,147 | (252 | ) | ||||
Change in fair value of available-for-sale debt securities classified as cash equivalents | 45 | — | |||||
Changes in assets and liabilities: | |||||||
Trade and other receivables, net | (3,705 | ) | 1,001 | ||||
Prepaid expenses and other assets | 1,176 | 213 | |||||
Accounts payable and accrued liabilities | (3,265 | ) | (105 | ) | |||
Operating lease liabilities | (108 | ) | (15 | ) | |||
Unearned revenue recognized under units-of-revenue method | (317 | ) | (490 | ) | |||
Net cash provided by (used in) operating activities | 2,198 | (4,947 | ) | ||||
Cash flows from investing activities: | |||||||
Payments of consideration under RPAs, AAAs and CPPAs | (8,000 | ) | (15,000 | ) | |||
Receipts under RPAs, AAAs and CPPAs | 1,307 | 7,771 | |||||
Purchase of property and equipment | — | (17 | ) | ||||
Net cash used in investing activities | (6,693 | ) | (7,246 | ) | |||
Cash flows from financing activities: | |||||||
Principal payments – debt | (5,066 | ) | (3,616 | ) | |||
Debt issuance costs and loan fees paid in connection with long-term debt | — | (581 | ) | ||||
Payment of preferred stock dividends | (1,368 | ) | (1,368 | ) | |||
Repurchases of common stock | (545 | ) | (13 | ) | |||
Proceeds from exercise of options and other share-based compensation | 325 | 1,956 | |||||
Taxes paid related to net share settlement of equity awards | (240 | ) | (1,334 | ) | |||
Net cash used in financing activities | (6,894 | ) | (4,956 | ) | |||
Net decrease in cash, cash equivalents and restricted cash | (11,389 | ) | (17,149 | ) | |||
Cash, cash equivalents and restricted cash at the beginning of the period | 106,416 | 159,550 | |||||
Cash, cash equivalents and restricted cash at the end of the period | $ | 95,027 | $ | 142,401 | |||
Supplemental Cash Flow Information: | |||||||
Cash paid for interest | $ | 6,078 | $ | 3,780 | |||
Cash paid for taxes | $ | 277 | $ | — | |||
Non-cash investing and financing activities: | |||||||
Accrual of contingent consideration under the Affitech CPPA | $ | — | $ | 3,000 | |||
Preferred stock dividend accrual | $ | 1,368 | $ | 1,368 | |||
Investor contact: Juliane Snowden XOMA Royalty Corporation +1-646-438-9754 juliane.snowden@xoma.com | Media contact: Kathy Vincent KV Consulting & Management +1-310-403-8951 kathy@kathyvincent.com |
1 https://ir.rezolutebio.com/news/detail/345/rezolute-receives-breakthrough-therapy-designation-from-fda-for-ersodetug-in-the-treatment-of-hypoglycemia-due-to-congenital-hyperinsulinism
2 https://ir.rezolutebio.com/news/detail/347/rezolute-provides-update-on-its-phase-3-sunrize-study-of-ersodetug-for-the-treatment-of-hypoglycemia-due-to-congenital-hyperinsulinism
3 https://ir.rezolutebio.com/news/detail/350/rezolute-announces-positive-recommendation-after-independent-interim-analysis-of-phase-3-sunrize-study-of-ersodetug-in-congenital-hyperinsulinism-hi
4 https://ir.rezolutebio.com/news/detail/354/rezolute-receives-breakthrough-therapy-designation-from-fda-for-ersodetug-in-the-treatment-of-hypoglycemia-due-to-tumor-hyperinsulinism
5 https://ir.dayonebio.com/news-releases/news-release-details/day-one-reports-first-quarter-2025-financial-results-and
6 https://ir.rezolutebio.com/news/detail/337/rezolute-announces-fda-clearance-of-ind-application-for-phase-3-registrational-study-of-rz358-for-treatment-of-hypoglycemia-due-to-tumor-hyperinsulinism
7 https://ir.gossamerbio.com/news-releases/news-release-details/gossamer-bio-announces-fourth-quarter-and-full-year-2024
8 https://ir.darebioscience.com/news-releases/news-release-details/dare-bioscience-announces-phase-3-plans-sildenafil-cream-36
