Welcome to our dedicated page for Xortx Therapeutics news (Ticker: XRTX), a resource for investors and traders seeking the latest updates and insights on Xortx Therapeutics stock.
XORTX Therapeutics Inc. develops therapies for gout and progressive kidney disease, with programs that include XRx-026 for gout, XRx-008 for autosomal dominant polycystic kidney disease, XRx-101 for acute kidney and other acute organ injury associated with respiratory virus infections, and XRx-225 for Type 2 diabetic nephropathy. The company also holds the VB4-P5 kidney anti-fibrotic program, a pre-IND asset targeting rare and prevalent forms of kidney disease.
Company announcements cover clinical and preclinical pipeline development, acquired kidney-disease assets, share consolidations, Nasdaq and TSX Venture Exchange listing matters, annual meeting results, board elections, auditor appointments, stock option plan approvals, and other governance actions tied to its public-company status.
XORTX Therapeutics has announced promising results from an independent study indicating that its proprietary formulation, XORLO™, effectively inhibits kidney expansion in a mouse model of Autosomal Dominant Polycystic Kidney Disease (ADPKD). Conducted at the University of Colorado, the study supports prior data presented at the American Society of Nephrology meeting. Key findings include a significant correlation between increased uric acid levels and kidney volume, with XORLO™ mitigating these harmful effects. CEO Allen Davidoff highlighted the relevance of these findings for future clinical trials.
XORTX Therapeutics (NASDAQ: XRTX) has announced the successful enrollment of participants in the XRX-OXY-101 Bridging Pharmacokinetics Study, aimed at optimizing the formulation and dosage of oxypurinol for treating ADPKD. The trial's completion and topline results are expected soon, which will inform the dosing for the upcoming Phase 3 XRX-OXY-301 trial. Additionally, the company granted 70,000 stock options to certain officers at an exercise price of $1.38 for five years, indicating ongoing engagement with its leadership team.
XORTX Therapeutics Inc. announced it has received a notification from Nasdaq regarding non-compliance with the minimum bid price rule, as its shares traded below $1.00 for 30 consecutive business days. Despite this, the company's listing on Nasdaq remains unaffected at this time. XORTX has 180 days to regain compliance. The firm is focused on developing therapies for progressive kidney diseases and has advanced clinical programs including XRx-008 for ADPKD and XRx-101 for acute kidney injury related to COVID-19.
XORTX Therapeutics has appointed Dr. Stacy Evans as Chief Business Officer to spearhead the search for a global partner for the Phase 3 development of its XRx-008 program, targeting autosomal dominant polycystic kidney disease (ADPKD). With nearly 25 years of experience, including 12 years at Pfizer, Dr. Evans will enhance the company's business development outreach. Additionally, Russo Partners will manage public relations for XORTX, further strengthening its market position. XRX-008 is poised for clinical trials in 2023, with recent patent grants aiding the program's progression.
XORTX Therapeutics announced the presentation of a peer-reviewed abstract at ASN Kidney Week 2022, highlighting findings from studies on XRx-008, a xanthine oxidase inhibitor. The research in rodent models of polycystic kidney disease (PKD) shows that increased uric acid levels worsen kidney function and structure, while XRx-008 significantly blocks these harmful effects. The data support the company’s application for Orphan Drug Designation for XRx-008, indicating potential for further development in treating PKD.
XORTX Therapeutics Inc. (NASDAQ: XRTX) announced that its President and CEO, Dr. Allen Davidoff, will speak at several upcoming investor conferences. These include the Sidoti & Company LLC Micro-Cap Virtual Conference on November 9-10, the A.G.P. Virtual Biotech Conference on November 30-December 1, and Singular Research's Best of the Uncovereds Conference on December 8 in San Francisco. XORTX is focused on developing innovative therapies for progressive kidney disease, including drugs like XRx-008 for ADPKD and XRx-101 for COVID-19 related organ injury.
XORTX Therapeutics announced receiving a new no objection letter from Health Canada regarding its XRX-OXY-101 clinical study for treating Autosomal Dominant Polycystic Kidney Disease (ADPKD). The study has been amended to include new objectives, including assessing food effects on the drug's bioavailability and characterizing different doses. CEO Dr. Allen Davidoff highlighted increased bioavailability of XRx-008. The findings will support the upcoming phase 3 trial and regulatory submissions to the FDA and EMA.
XORTX Therapeutics Inc. (NASDAQ: XRTX) announced the online availability of a peer-reviewed abstract for the ASN Kidney Week 2022 conference. The study, highlighting the effects of elevated uric acid on polycystic kidney disease (PKD) in rodent models, indicates that increased uric acid leads to significant kidney damage, evidenced by increased kidney weight, creatinine levels, and cyst index. The findings support the company's XRx-008 program aimed at treating ADPKD and could enhance its patent portfolio. The presentation will be by Dr. Charles Edelstein and Dr. Allen Davidoff on November 4, 2022.
XORTX Therapeutics has completed a public offering, raising US$5 million through the sale of 1.4 million Common Share Units at US$1.00 each and 3.6 million Pre-Funded Units at US$0.9999 each. This offering includes common shares and warrants, allowing immediate separability upon issuance. Additionally, the company reduced the exercise price of prior warrants from US$4.77 to US$1.17. The registration statement was declared effective on September 22, 2022.
XORTX Therapeutics Inc. (NASDAQ: XRTX) has announced a public offering of 1.4 million common share units priced at $1.00 each, alongside 3.6 million pre-funded warrant units at $0.9999, aiming for gross proceeds of $5 million. The offering is set to close by October 6, 2022, pending customary conditions. Additionally, the company plans to reduce the exercise price of outstanding warrants from $4.77 to $1.17 post-offering. A.G.P./Alliance Global Partners is the sole book-running manager for this offering.