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Triera Biosciences - a Zentek Company - Launches Contract Research Organization Services for Custom Aptamer Discovery, Biosensor Enablement, and Machine-Learning Classification

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Triera Biosciences (NASDAQ:ZTEK) is launching contract research organization services for custom aptamer discovery, biosensor enablement, and ML classification support on March 25, 2026.

Built on an exclusive 20-year McMaster University license, Triera offers integrated SELEX aptamer development, biosensor integration, and optional ML signal classification targeting infectious disease and oncology diagnostics across North America and Europe.

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Positive

  • Exclusive 20-year McMaster license for aptamer technology
  • Reported sub-nanomolar binding (Kd) for selected research targets
  • Catalog includes aptamers for influenza A, SARS-CoV-2, VEGF, syphilis, norovirus, C. difficile
  • Asset-light, client-funded CRO model while retaining IP
  • Addresses diagnostics markets cited up to USD 155B (cancer diagnostics projection)

Negative

  • None.

News Market Reaction – ZTEK

-2.75%
-2.75% Session close to close

In the Mar 25 session, ZTEK declined 2.75%, reflecting a moderate negative market reaction.

Data tracked by StockTitan Argus on the day of publication.

Market Context

This announcement details Triera’s move into CRO services for custom aptamer discovery, biosensor en...
Analysis

This announcement details Triera’s move into CRO services for custom aptamer discovery, biosensor enablement, and ML classification, backed by a 20-year exclusive McMaster license and targeting large diagnostic markets in infectious disease and oncology. It reinforces Zentek’s pivot toward asset-light, IP commercialization and earlier revenue. Recent history shows mixed price reactions to otherwise positive updates, so progress on concrete contracts, Albany Graphite milestones, and regulatory steps for ZenGUARD may be key markers to watch.

Key Figures

Exclusive license term: 20 years Influenza A market: USD 1.5B Influenza A projected: USD 2.6B +5 more
8 metrics
Exclusive license term 20 years McMaster University worldwide royalty-bearing aptamer license
Influenza A market USD 1.5B Rapid influenza diagnostics market size in 2025
Influenza A projected USD 2.6B Projected rapid influenza diagnostics market by 2033
Syphilis diagnostics USD 1.1B STI diagnostics market size in 2024
Syphilis projected USD 2.5B+ Projected STI diagnostics market by 2032
Cancer diagnostics USD 109.6B Global cancer diagnostics market size in 2024
Cancer diagnostics projected USD 155B Projected global cancer diagnostics market by 2030
Norovirus burden USD 60B Annual global economic burden of norovirus

Historical Context

5 past events · Latest: Mar 13 (Positive)
Pattern 5 events
Date Event Sentiment 24h Move Catalyst
Mar 13 Litigation outcome Positive -1.9% Favorable court judgment dismissing most claims tied to former CEO.
Mar 09 Project engagement update Positive +0.5% PDAC 2026 update on government and First Nations engagement for Albany.
Mar 04 Commercial pilot program Positive +0.0% Pilot evaluation with Quality Filters to test Zentek filtration media.
Feb 26 Project advancement plan Positive +4.9% Plan to advance Albany Graphite toward new PEA and PFS with funding focus.
Feb 25 Nasdaq compliance extension Negative +1.2% 180-day extension to regain compliance with $1.00 minimum bid price.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Pattern Detected

Recent news often saw mixed or contrary price reactions, with more divergences than alignments to headline tone.

Recent Company History

Over the past months, Zentek has focused on litigation resolution, core-platform sharpening, and advancing Albany Graphite, ZenGUARD, and Triera. A favorable court judgment on Mar 12, 2026 was followed by a mild negative move, while government engagement and a new PEA plan for Albany on Feb 26, 2026 coincided with a 4.89% gain. Compliance extensions from Nasdaq saw modest positives. Today’s CRO-launch announcement for Triera fits the ongoing pivot toward IP-led, B2B commercialization and earlier-revenue initiatives.

Key Terms

aptamer, biosensor, machine-learning, vascular endothelial growth factor, +3 more
7 terms
aptamer medical
"Triera plans to begin offering ... services for custom aptamer discovery, biosensor enablement"
An aptamer is a short strand of DNA, RNA or a small protein engineered to stick tightly and specifically to a particular molecule, like a lock fitting a key. Investors care because aptamers can function like artificial antibodies for diagnostics, drugs, or targeted delivery, offering potential advantages in cost, stability and manufacturing that can affect a product’s development speed, regulatory path and commercial value.
biosensor technical
"services for custom aptamer discovery, biosensor enablement, and machine-learning ("ML") classification"
A biosensor is a device that detects biological signals—such as proteins, DNA, or metabolites—and converts them into readable electronic or visual data, like a smoke detector that senses a problem and triggers a readable alert. For investors it matters because biosensors can enable faster, cheaper, and more frequent medical tests or environmental monitoring, creating sales, recurring consumable demand, and potential regulatory milestones that can materially affect a company’s revenue and valuation.
machine-learning technical
"biosensor enablement, and machine-learning ("ML") classification support to pharmaceutical"
Machine-learning is a type of computer software that improves its performance by finding patterns in data rather than following fixed rules. Think of it like a digital apprentice that gets better at tasks — such as spotting customer trends, predicting demand, or automating routine work — the more examples it sees. Investors care because machine-learning can boost revenue, cut costs, create competitive advantages, and introduce new risks tied to data quality and model errors.
vascular endothelial growth factor medical
"vascular endothelial growth factor (VEGF, a solid tumour biomarker), syphilis, norovirus"
Vascular endothelial growth factor (VEGF) is a naturally occurring protein that signals the body to grow new blood vessels—think of it like a fertilizer for blood vessels. It matters to investors because many drugs either block or mimic VEGF to treat conditions such as cancers and certain eye diseases; clinical trial outcomes, regulatory approvals, or safety issues tied to VEGF-targeting therapies can materially affect a company’s revenue prospects and stock value.
vegf medical
"vascular endothelial growth factor (VEGF, a solid tumour biomarker), syphilis, norovirus"
Vascular endothelial growth factor (VEGF) is a naturally occurring protein that signals the body to grow new blood vessels, like a fertilizer prompts plants to sprout. It matters to investors because drugs that block or mimic VEGF can dramatically change outcomes for cancers and eye diseases, making them major drivers of clinical trial results, regulatory approvals, market value and future revenue potential for biopharma companies.
clostridioides difficile medical
"norovirus, and Clostridioides difficile, among others under development, with binding"
Clostridioides difficile is a bacterium that can overgrow in the gut after antibiotics and cause severe, sometimes recurring, diarrhea and inflammation; it spreads easily in hospitals and care facilities. Investors care because it drives demand for diagnostics, new drugs, vaccines and infection-control services, can raise hospital costs and liability risks, and creates a steady market for companies offering prevention or treatment—like a persistent malfunction that keeps repair business steady.
cagr financial
"USD 1.5B (2025, rapid influenza diagnostics) USD 2.6B projected by 2033 | 7.1% CAGR 2025-2033"
Compound Annual Growth Rate (CAGR) measures the average yearly growth of an investment, revenue, or other metric over a multi-year period as if it had grown at a steady rate each year. Think of it like the constant speed that would take you from the starting value to the ending value over the same time—useful because it smooths out ups and downs and lets investors compare different assets or performance periods on an even footing.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Backed by an Exclusive 20-Year McMaster University License, Triera Targets High-Priority Infectious Disease and Oncology Detection Markets Across Canada, the United States, and Europe

GUELPH, ON / ACCESS Newswire / March 25, 2026 / Zentek Ltd. (TSXV:ZEN)(NASDAQ:ZTEK) ("Zentek" or the "Company") announces that its wholly-owned subsidiary, Triera Biosciences Ltd. ("Triera"), plans to begin offering contract research organization ("CRO") services for custom aptamer discovery, biosensor enablement, and machine-learning ("ML") classification support to pharmaceutical, biotechnology, and diagnostics organizations in Canada, the United States, Europe, and other markets that require high-performance molecular recognition tools but do not have in-house SELEX expertise, biosensor engineering capability, or ML classification systems to develop them.

A Differentiated Platform Built on Deep Science

Triera's aptamer discovery capabilities were developed in collaboration with Dr. Yingfu Li's research team at McMaster University, a globally recognized leader in functional nucleic acid chemistry and SELEX methodology. Triera holds an exclusive, worldwide, royalty-bearing license from McMaster University to use and practice aptamer applications developed through this collaboration for the next 20 years: a durable scientific foundation the Company believes represents a meaningful competitive position in the CRO services landscape.

What distinguishes Triera's CRO model is its integration of three capabilities within a single engagement: (i) custom aptamer discovery and optimization via SELEX, (ii) biosensor engineering and integration support, and (iii) optional ML classification systems for signal interpretation. Aptamers are chemically synthesized, enabling consistent batch-to-batch production, rapid iteration, and defined stability profiles - structural advantages over antibody-based molecular recognition tools in certain diagnostic and sensing applications.

Triera's current catalogue contains aptamers for clinically and commercially significant targets including influenza A, SARS-CoV-2, vascular endothelial growth factor (VEGF, a solid tumour biomarker), syphilis, norovirus, and Clostridioides difficile, among others under development, with binding affinity values (Kd) reported in the sub-nanomolar range for selected research targets.

Target Disease Areas - Global Burden & Addressable Market*

Target

Global Disease Burden

Diagnostic Market Size

Growth Rate

Influenza A

3-5M severe illness cases/year 290K-650K respiratory deaths/year H5N1 pandemic risk actively monitored globally

USD 1.5B (2025, rapid influenza diagnostics) USD 2.6B projected by 2033

7.1% CAGR 2025-2033

Syphilis

8M new adult cases/year 230K deaths/year 700K congenital syphilis cases (2022)

USD 1.1B (2024, STI diagnostics) USD 2.5B+ projected by 2032

9.8% CAGR 2024-2032

VEGF (a cancer biomarker)

18M new cases/year; 9.0M deaths; 35M+ projected by 2050 (+77%) 1 in 5 people develop cancer in their lifetime

USD 109.6B (2024, cancer diagnostics) USD 155B projected by 2030

6.1% CAGR 2024-2030

Norovirus

685M cases/year 200K deaths/year USD 60B annual global economic burden

USD 800M+ (2024, GI molecular diagnostics) No FDA-approved vaccine - active diagnostics gap

~8% CAGR

(GI diagnostics)

C. difficile

Fastest-growing diarrheal pathogen burden globally DALYs ~doubled 1990-2021 8.3% 30-day case fatality rate

USD 560M+ (2024, CDI diagnostics) Institutional procurement channel well-established

~7% CAGR

(HAI diagnostics)

Asset-Light CRO Model: Client Funded, IP Retained

Triera operates as an upstream molecular recognition supplier: it develops and delivers validated aptamer sequences and biosensor-ready outputs to pharmaceutical, biotechnology, and diagnostics manufacturers, while retaining ownership of all underlying intellectual property. Client engagements are structured to be funded by the client, consistent with Zentek's broader asset-light, IP-commercialization strategy.

In alignment with Zentek's strategic focus, Triera expects these planned CRO activities may help generate earlier and more predictable revenue, supporting internal development capacity and the Company's broader diagnostic and pharmaceutical product initiatives. Successful engagements may expand into follow-on programs and, where appropriate, licensing or product partnerships. Organizations interested in exploring a project can contact the Company using the information below.

Commentary

"Triera was built to commercialize a deep body of aptamer science into real-world diagnostics and therapeutics," said Mohammed (Moe) Jiwan, Chief Executive Officer of Zentek Ltd. "Our platform is grounded in one of the world's leading academic aptamer programs, protected by a 20-year exclusive license, and aligned with the most urgent diagnostic gaps in infectious disease and oncology across North America and Europe. By offering CRO services, we can help pharmaceutical and biotech teams access custom molecular recognition tools and accelerate their development timelines, while generating near-term revenue that supports Triera's long-term product roadmap."

About Triera Biosciences Ltd.

Triera holds an exclusive, worldwide, royalty-bearing license from McMaster University to use and practice aptamer applications developed through the collaboration with the Li Lab for the next 20 years. Triera and McMaster's combined expertise and capabilities in aptamer technology offer potential to reduce the cost and time required for the development of new treatments.

About Zentek

Zentek Ltd. is a Canadian intellectual property development and commercialization company advancing a portfolio of graphene-enabled and advanced material technologies across clean air, next-generation materials, and critical minerals. The Company's core platforms are Albany Graphite, ZenGUARD™, and Triera.

Forward-Looking Statements

This news release contains forward-looking statements. Since forward-looking statements address future events and conditions, by their very nature they involve inherent risks and uncertainties. Although Zentek believes that the assumptions and factors used in preparing the forward-looking information in this news release are reasonable, undue reliance should not be placed on such information, which only applies as of the date of this news release, and no assurance can be given that such events will occur in the disclosed time frames or at all. Zentek disclaims any intention or obligation to update or revise any forward-looking information, whether as a result of new information, future events or otherwise, other than as required by law.

Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

*Table sources (burden; market): (1) Influenza A: World Health Organization (WHO), "The burden of influenza" (30 Mar 2024) (3-5M severe cases; 290K-650K respiratory deaths/yr); Data Bridge Market Research, "Global Rapid Influenza Diagnostics Market...Forecast to 2033" (accessed Mar 24, 2026) (USD 1.50B 2025; USD 2.72B 2033; CAGR 7.75%). (2) Syphilis: WHO/United Nations Office at Geneva, "WHO reports major increase in sexually transmitted infections" (21 May 2024) (8M new adult cases in 2022; 230K deaths); WHO (GHO), "Data on syphilis" (accessed Mar 24, 2026) (context re congenital syphilis); Mordor Intelligence, "STD Diagnostics Market...(2020-2031)" (accessed Mar 24, 2026) (market estimates; methodology per publisher). (3) Cancer/VEGF: International Agency for Research on Cancer (IARC), "New report on global cancer burden in 2022..." (4 Apr 2024) / Bray et al., CA Cancer J Clin (2024) (≈20M new cases; 9.7M deaths; 35M by 2050; +77%); Grand View Research, "Cancer Diagnostics Market...(2025-2030)" (accessed Mar 24, 2026) (USD 109.61B 2024; USD 155.07B 2030; CAGR 6.14%). (4) Norovirus: WHO, "Norovirus" (updated Apr 30, 2022; accessed Mar 24, 2026) and U.S. CDC, "Norovirus Facts and Stats" (8 May 2024) (≈685M cases/yr; ≈200K deaths/yr; ≈USD 60B economic burden); market estimates per third-party publisher as noted above. (5) C. difficile: Global Burden of Disease (GBD) 2021-based analyses (e.g., Xia et al., Annals of Medicine (2025) / Chen et al., Antibiotics (2025)) (1990-2021 burden trends); additional peer-reviewed analysis (Zhao et al., Eur J Clin Microbiol Infect Dis (6 Mar 2026)) (1990-2021 trends); market estimates per third-party publisher as noted above. Market size and growth figures are third-party estimates provided for reference only; such estimates may differ by source methodology and are not indicative of Zentek's actual or future performance. This information is provided for reference only and may not be indicative of Zentek's actual or future performance

For further information:

Mohammed (Moe) Jiwan
Chief Executive Officer, Zentek Ltd.
T: 416-709-8876
E: mjiwan2@zentek.com
W: www.zentek.com

SOURCE: Zentek Ltd.



View the original press release on ACCESS Newswire

FAQ

What CRO services is Triera (ZTEK) launching on March 25, 2026?

Triera is launching custom aptamer discovery, biosensor enablement, and ML classification services. According to the company, the offering integrates SELEX aptamer development, sensor engineering, and optional machine-learning signal interpretation for diagnostics and pharma partners.

How long is Triera's exclusive aptamer license with McMaster for ZTEK?

Triera holds an exclusive, worldwide, royalty-bearing license for 20 years. According to the company, the license underpins its aptamer platform and commercialization rights developed with McMaster research collaborators.

Which disease targets does Triera (ZTEK) list in its aptamer catalogue?

Triera's catalogue includes aptamers for influenza A, SARS-CoV-2, VEGF, syphilis, norovirus, and C. difficile. According to the company, additional targets remain under development with reported sub-nanomolar Kd for select targets.

How is Triera's CRO model structured for clients and IP ownership?

Triera operates an asset-light, client-funded CRO model while retaining underlying IP. According to the company, clients fund projects and receive validated aptamer sequences and biosensor-ready outputs, with Triera keeping IP ownership.

What market opportunity does Triera (ZTEK) target with its CRO services?

Triera targets infectious disease and oncology diagnostics across Canada, the US, and Europe with large addressable markets. According to the company, cited market figures include up to USD 155B for cancer diagnostics projected by 2030.