Zura Bio Limited Stock Price, News & Analysis

Zura Bio (NASDAQ: ZURA) has launched TibuSHIELD, a global Phase 2 clinical study evaluating tibulizumab in adults with moderate to severe hidradenitis suppurativa (HS). The study will be the first to evaluate dual inhibition of B-cell activating factor (BAFF) and interleukin-17A (IL-17A) pathways in HS patients. The trial will enroll approximately 180 adults across the United States, Canada, and Europe, spanning 28 weeks with a 16-week primary efficacy assessment and 12-week safety follow-up, plus an optional open-label extension. Topline results for the primary efficacy endpoint are expected in Q3 2026. This launch follows the December 2024 initiation of TibuSURE, another Phase 2 study evaluating tibulizumab in systemic sclerosis patients.

Zura Bio (NASDAQ: ZURA) reported its Q1 2025 financial results and corporate updates. The company ended Q1 with $170.6 million in cash, expected to fund operations through 2027. Key developments include advancing the Phase 2 TibuSURE trial for tibulizumab in systemic sclerosis and preparing for a Phase 2 trial in hidradenitis suppurativa, set to begin in Q2 2025. The company reported a net loss of $17.4 million ($0.19 per share) compared to $7.7 million ($0.02 per share) in Q1 2024. R&D expenses increased to $10.5 million from $3.6 million year-over-year, while G&A expenses rose to $8.8 million from $4.8 million. The company also strengthened its team by appointing Kate Dingwall as SVP of Development Operations.

Zura Bio (NASDAQ: ZURA) reported its full year 2024 financial results, highlighting significant operational and financial achievements. The company completed a $112.5 million private placement in April 2024, ending the year with $176.5 million in cash and cash equivalents, providing runway through 2027.

Key developments include initiating the Phase 2 TibuSURE trial for systemic sclerosis and plans to launch a Phase 2 study for hidradenitis suppurativa in Q2 2025. Financial results show R&D expenses decreased to $24.4 million from $44.0 million in 2023, while G&A expenses increased to $30.8 million from $18.6 million. The company reported a net loss of $45.4 million ($0.60 per share) compared to $69.2 million ($2.09 per share) in 2023.

Zura Bio (Nasdaq: ZURA), a clinical-stage immunology company focused on developing dual-pathway antibodies for autoimmune and inflammatory diseases, has announced its participation in the upcoming Leerink Partners Global Healthcare Conference. The company's senior leadership team will engage in a fireside chat on Tuesday, March 11, 2025, at 1:40 p.m. ET in Miami, FL, where they will also host investor meetings.

The presentation will be accessible through a live webcast on the News & Events page of Zura Bio's website's Investors & Media section. For those unable to attend, a replay will be available and archived on the website for a minimum of 30 days after the event.

Zura Bio (NASDAQ: ZURA) has launched TibuSURE, a global Phase 2 study evaluating tibulizumab for treating systemic sclerosis (SSc) in adults. The study marks the first clinical trial designed to investigate both anti-BAFF and IL-17 pathways in systemic sclerosis. Tibulizumab's dual-pathway approach aims to provide deeper efficacy compared to single-pathway inhibition, which has shown modest effects in rheumatic diseases like SSc.

The company believes this novel strategy of concurrently targeting two pivotal pathways involved in inflammation and fibrosis could address the multi-organ pathology of SSc, a heterogeneous and complex autoimmune disease with effective therapies currently available.

Zura Bio (Nasdaq: ZURA), a clinical-stage immunology company focusing on dual-pathway antibodies for autoimmune and inflammatory diseases, has announced its participation in the Piper Sandler 36th Annual Healthcare Conference. The company's senior leadership team will engage in a fireside chat on Tuesday, December 3, 2024, at 9:00 a.m. ET in New York, NY, and will conduct investor meetings. A live webcast and replay of the presentation will be accessible on the company's website's Investors section under 'News & Events,' remaining available for at least 30 days after the event.

Zura Bio (Nasdaq: ZURA) has submitted a protocol to the FDA for a Phase 2 study of tibulizumab, a dual-pathway antibody targeting IL-17A and BAFF, for treating systemic sclerosis in adults. The planned double-blind, randomized study will evaluate safety, tolerability, and efficacy in approximately 80 participants with early diffuse cutaneous systemic sclerosis. The trial aims to demonstrate improvements in skin and lung symptoms and includes an open-label extension. Expected to begin in Q4 2024, the company has already submitted an Orphan Drug Designation request to the FDA.

Zura Bio (NASDAQ: ZURA) reported Q3 2024 financial results with a net loss of $22.9 million ($0.26 per share), compared to $8.3 million ($0.18 per share) in Q3 2023. The company maintains a strong cash position of $188.2 million, expected to fund operations through 2027. Research and development expenses increased to $6.0 million, while general and administrative expenses rose to $13.3 million.

The company plans to initiate Phase 2 trials for tibulizumab in systemic sclerosis (Q4 2024) and hidradenitis suppurativa (Q2 2025). An Orphan Drug Designation application was submitted to the FDA for systemic sclerosis treatment.

Zura Bio (Nasdaq: ZURA), a clinical-stage immunology company focused on developing dual-pathway antibodies for autoimmune and inflammatory diseases, has announced its participation in two major investor conferences this November. The company will participate in a fireside chat at the Guggenheim Inaugural Healthcare Innovation Conference on November 12, 2024, at 1:00 p.m. ET in Boston, and will host investor meetings at the Jefferies London Healthcare Conference on November 21, 2024, in London. Webcasts and replays will be available on Zura Bio's website's News & Events page for at least 30 days after the events.