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Zura Bio Limited reports news on its clinical-stage immunology pipeline for autoimmune and inflammatory diseases. The company develops dual-pathway antibody candidates, led by tibulizumab (ZB-106), which targets IL-17A and BAFF and is being evaluated in Phase 2 studies for hidradenitis suppurativa and systemic sclerosis. Its additional clinical-stage candidates include crebankitug (ZB-168), targeting IL-7R, and torudokimab (ZB-880), targeting IL-33.
Recurring updates cover clinical study designs and presentations, financial results, corporate presentations, leadership and board changes, equity incentive grants, and capital-raising activity involving Class A ordinary shares and pre-funded warrants.
Zura Bio (Nasdaq: ZURA), a clinical-stage immunology company, has announced its participation in three upcoming investor conferences in September 2024. The company will present at the H.C. Wainwright 26th Annual Global Investment Conference on September 11 at 11:30 a.m. ET, the Stifel Immunology and Inflammation Virtual Summit on September 17 at 12:00 p.m. ET, and the Cantor Global Healthcare Conference on September 17 at 2:30 p.m. ET.
Zura Bio's senior leadership team will host investor meetings at these events, with the Stifel summit being virtual. Live webcasts and replays of the presentations will be available on the company's website for at least 30 days following each event.
Zura Bio (Nasdaq: ZURA) reported Q2 2024 financial results and business highlights. Key points include:
- Presented tibulizumab data at EULAR 2024, showing potential for dual inhibition of IL-17A and BAFF in autoimmune diseases
- Plans to initiate Phase 2 studies for tibulizumab in systemic sclerosis (Q4 2024) and hidradenitis suppurativa (Q2 2025)
- Appointed Robert Lisicki as CEO and formed Scientific Advisory Board
- Cash position of $188.4 million as of June 30, 2024, expected to support operations through 2027
- Q2 2024 net loss of $12.7 million ($0.17 per share)
- R&D expenses decreased to $5.5 million, while G&A expenses increased to $6.2 million
Zura Bio (Nasdaq: ZURA) has completed its exchange offer and consent solicitation for outstanding public and private placement warrants. The company issued 3,235,184 ordinary shares in exchange for tendered IPO warrants. Zura Bio will exercise its right to exchange all remaining untendered IPO warrants at a ratio of 0.27 Class A ordinary shares per warrant on August 27, 2024. As a result, no IPO warrants will remain outstanding, leading to their suspension from trading on Nasdaq as of August 26, 2024, and subsequent delisting. The company's Class A ordinary shares will continue to trade on Nasdaq under the symbol 'ZURA'.
Zura Bio (Nasdaq: ZURA) has announced the expiration and results of its exchange offer and consent solicitation for outstanding public and private placement warrants. 97.2% of public warrants and 69.0% of private placement warrants were validly tendered. The company expects to accept all validly tendered IPO warrants for exchange and settlement by August 12, 2024. The consent solicitation received approval for the Warrant Amendment, allowing Zura Bio to require conversion of remaining warrants at a 10% lower ratio than the exchange offer. Zura Bio plans to execute the Warrant Amendment and exercise its right to exchange all remaining untendered IPO warrants, after which no IPO warrants will remain outstanding.
Zura Bio, a clinical-stage immunology company (NASDAQ: ZURA), has announced an exchange offer and consent solicitation for its public and private placement warrants issued during its initial public offering. The company aims to simplify its capital structure and reduce potential dilution by offering 0.30 Class A ordinary shares for each outstanding IPO warrant. This exchange offer could result in issuing up to 3,842,999 new shares, an approximate 6% increase in outstanding shares. Concurrently, Zura Bio seeks consents to amend the warrant agreement to enforce the exchange of all remaining warrants at 0.27 shares per warrant if the offer succeeds. The offer period ends on August 8, 2024. Parties holding 40.7% of public warrants and 65.3% of private placement warrants have already agreed to tender their warrants.
Zura Bio presented data on tibulizumab (ZB-106) at EULAR 2024, demonstrating promising results in treating Sjogren's syndrome and rheumatoid arthritis (RA). The Phase 1 study showed tibulizumab was well-tolerated and effective in neutralizing IL-17A and BAFF, reducing B cell counts and modulating inflammatory mediators in 25 participants. Preclinical data in a RA mouse model indicated significant reductions in disease scores and inflammation when both IL-17A and BAFF were inhibited. The studies suggest tibulizumab's potential as a dual-pathway treatment for autoimmune diseases.
Zura Bio, a clinical-stage immunology company, has formed a Scientific Advisory Board (SAB) with experts in rheumatology, dermatology, and immunology. The board includes Johann Gudjonsson, Dinesh Khanna, Ajay Nirula, Michael Weinblatt, and Steven Ziegler. This initiative aims to advance their clinical and translational science efforts, particularly in Phase 2 clinical development for systemic sclerosis and hidradenitis suppurativa. The SAB will also focus on the roles of BAFF and IL-17A in autoimmune and inflammatory diseases, enhancing Zura Bio's research and clinical trials.
Zura Bio, a clinical-stage immunology company, announced its scheduled presentation at EULAR 2024 in Vienna from June 12-15. The company will unveil data on tibulizumab (ZB-106), a dual-pathway antibody targeting IL-17A and BAFF, focusing on its potential for treating Sjogren's syndrome and rheumatoid arthritis. The data aims to illustrate the antibody's capacity to inhibit both pathways in a single therapy, potentially broadening its clinical applications across various autoimmune diseases. Zura Bio also disclosed timelines for Phase 2 trials: systemic sclerosis in Q4 2024 and hidradenitis suppurativa in Q2 2025.
Zura Bio, a clinical-stage immunology company with a focus on novel dual-pathway antibodies for autoimmune and inflammatory diseases, announced participation in two June investor conferences. Chief Scientific Officer Michael Howell will attend one-on-one meetings at the Jefferies Global Healthcare Conference on June 6, 2024, in New York. CEO Robert Lisicki will participate in a panel discussion on dermatological disorders and hold one-on-one meetings at the Oppenheimer Novel Targets in Immunology Summit on June 24, 2024, in New York. These events aim to strengthen investor relations and provide insights into Zura Bio's innovative clinical programs.
Zura Bio reported financial results for Q1 2024, ending with $89.8M in cash and closing an oversubscribed $112.5M private placement in April. The company appointed a new CEO and CMO and is on track to start Phase 2 studies for SSc and HS. Cash runway extended through 2027. R&D expenses decreased, while G&A expenses increased. Net loss reduced. Anticipated milestones include Phase 2 trials for ZB-106 and monitoring of ZB-168 and ZB-880.