Crescent Biopharma Inc Stock Price, News & Analysis

Catalyst Biosciences announced its participation in the Piper Sandler 33rd Annual Virtual Healthcare Conference scheduled from November 29 to December 2, 2021. Members of the executive team will engage in a fireside chat accessible on-demand starting November 22, 2021, at 10:00 am ET. This event will be available for registered attendees until the conference concludes. The company focuses on protease therapeutics aimed at disorders of the complement system, including its preclinical C3-degrader program licensed to Biogen. An archived webcast will be available for 90 days post-conference.

Catalyst Biosciences (CBIO) reported its Q3 2021 financial results and announced the discontinuation of MarzAA development to focus on complement therapeutics. The decision stems from enrollment challenges and competition in clinical trials. The company plans to seek buyers for its hemophilia assets and anticipates a 40% reduction in burn rate. Financially, Q3 net loss was $25.2 million, compared to $16 million a year prior, with cash reserves of $64.5 million. Catalyst aims to advance its complement program, with notable progress in CB 4332 and ongoing trials.

Catalyst Biosciences, Inc. (NASDAQ: CBIO) announced that Dr. Grant Blouse will present at two scientific conferences from October 26-30, 2021. The presentations will focus on the ProTUNE™ platform, engineered for potency and specificity in complement-mediated disorders. Dr. Blouse expressed excitement about ProTUNE™ and its C3b/C4b degraders' potential in precision medicine. Catalyst's pipeline includes CB 4332, an enhanced complement factor I protease expected to enter clinical trials in 2022, alongside late-stage programs for treating rare bleeding disorders.

Catalyst Biosciences, Inc. (NASDAQ: CBIO) announced the resignation of its CFO, Clinton Musil, effective October 29, 2021, for personal reasons. Seline Miller, the controller, is elevated to interim CFO and principal accounting officer while a successor is sought. The CEO, Nassim Usman, expressed gratitude for Musil's contributions as the company advances in its Protease Medicines platform. Catalyst is focused on rare disorders with late-stage programs like MarzAA and preclinical candidates targeting rare diseases.

Catalyst Biosciences, Inc. (NASDAQ: CBIO) announced that the U.S. FDA has granted Orphan Drug Designation for its candidate, Marzeptacog alfa (MarzAA), aimed at treating Factor VII Deficiency (FVIID). This is the second ODD for MarzAA, which also holds Fast Track Designation for treating Hemophilia A/B with inhibitors and FVIID. The Orphan Drug Designation supports drug development for rare diseases, providing tax credits and marketing exclusivity. Catalyst focuses on rare disorders of the coagulation and complement systems, with MarzAA being a key part of its late-stage clinical programs.

Catalyst Biosciences (NASDAQ: CBIO) will participate in a fireside chat at the Cantor Global Healthcare Conference on September 29, 2021, at 10:00 am ET. Members of the executive management team will discuss the company's advancements, including its late-stage clinical programs targeting rare disorders. Investors can access the live webcast here, with an archived version available for 90 days.

Catalyst Biosciences reported that its management team will participate in a fireside chat on September 15, 2021, focusing on advancements in its complement portfolio, particularly CB 2782-PEG for dry age-related macular degeneration (AMD). The discussion will cover key programs including CB 4332 and various C3 and C4 degraders. The company highlighted its commitment to addressing unmet needs in rare disorders and the potential advantages of its preclinical and clinical candidates. A replay of the call will be available on its website.

Catalyst Biosciences (NASDAQ: CBIO) recently presented at the International Conference on Complement Therapeutics (ICCT) from September 8-13, 2021. The focus was on the engineered Complement Factor I (CFI), particularly CB 4332, demonstrating improved pharmacokinetics and efficacy compared to plasma-derived CFI in preclinical models. This first-in-class product aims for weekly subcutaneous administration in patients with CFI deficiency. Catalyst has initiated the ConFIrm study to confirm CFI deficiencies, supporting future IND submissions and global clinical trials for CB 4332.

Catalyst Biosciences (NASDAQ: CBIO) announced the appointment of Jeanne Jew to its Board of Directors, bringing over 25 years of corporate development experience. CEO Nassim Usman expressed excitement regarding her expertise to support the advancement of the company’s Protease Medicines pipeline. Jew has held significant roles in various biopharmaceutical companies, enhancing strategic planning and business development. Catalyst focuses on addressing unmet medical needs in rare disorders with its protease engineering platform, which includes late-stage clinical programs like MarzAA.