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OptimizeRx Corporation (OPRX) Stock Price, News & Analysis

OPRX NASDAQ
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Price Move History

Daily moves over 5%
47 252 sessions, November 6, 2025 to November 6, 2026
Largest daily move
+24.7% close of August 13, 2026
1-year change
-53.7% closing prices, November 6, 2025 to November 6, 2026
1-month change
-0.6% closing prices, October 6, 2026 to November 6, 2026

Company Description

OptimizeRx Corporation (Nasdaq: OPRX) is a healthcare technology company that focuses on helping life science brands connect with patients and healthcare professionals (HCPs). According to company disclosures, its platform is built to support life sciences companies in reaching and engaging HCPs and patients through data-driven, privacy-safe tools that align healthcare marketing with real-world clinical needs.

OptimizeRx operates in the healthcare market in the United States and is headquartered in Waltham, Massachusetts. The company is described as working with pharmaceutical and life sciences organizations to improve how therapies are presented and supported across both healthcare professional and direct-to-consumer (DTC) channels. Its solutions are designed to support patient access to medications and to coordinate messaging across multiple points in the care journey.

Business focus and platform capabilities

The company states that its platform combines AI-driven tools such as the Dynamic Audience Activation Platform (DAAP) and proprietary Micro-Neighborhood® audiences or Micro-Neighborhood Targeting (MNT). These tools are used to deliver timely, relevant, and hyper-local engagement that aligns with brand eligibility signals and real-world healthcare data. By using deterministic audience cohorts and privacy-safe data, OptimizeRx aims to help life science brands identify clinically relevant patient and provider audiences and coordinate outreach across channels.

Earlier descriptions of OptimizeRx also highlight digital health messaging delivered via electronic health records (EHRs) and electronic prescribing (eRx) platforms. Through these in-workflow point-of-care (POC) channels, the company has offered capabilities such as financial messaging, brand and clinical messaging, brand support, and patient engagement. These offerings are intended to support patient adherence to medications by providing access to financial assistance, prior authorization support, education, and clinical information within clinical workflows.

Engagement across HCP and DTC channels

Company materials emphasize that OptimizeRx seeks to bridge the gap between HCP-focused and DTC strategies. Its tools are described as enabling synchronized marketing solutions that connect point-of-care messaging, omnichannel media, and hyper-local targeting. This includes the use of Micro-Neighborhood® audiences that are built from privacy-safe clinical and consumer data to form deterministic cohorts aligned to brand eligibility signals. These cohorts can be activated across major media channels, including digital and out-of-home (OOH) advertising through partnerships.

For example, OptimizeRx has described collaborations where its Micro-Neighborhood® Targeting data is integrated with external media networks to support clinically relevant campaigns at granular geographic levels, such as ZIP+4 or ZIP+9. In these cases, the company’s data is used to align disease prevalence and brand eligibility signals with media inventory, enabling pharmaceutical and healthcare brands to reach audiences that are more likely to be clinically relevant for specific therapies.

Point-of-care network and partnerships

OptimizeRx reports that it maintains an in-workflow point-of-care network built through partnerships with electronic health record vendors, e-prescribing platforms, health systems access partners, and other technology companies. The company has announced multi-year agreements and renewals with EHR and eRx partners, including exclusive arrangements for certain platforms. These relationships expand its reach to healthcare providers directly in the clinical workflow, including at the point of discharge and when treatment plans and patient instructions are finalized.

Through these partnerships, OptimizeRx indicates that it can increase its National Provider Identifier (NPI) reach and provide life sciences brands with access to premium inventory within clinical systems. The company has highlighted that these agreements improve visibility into future channel revenue and support its positioning in the point-of-care marketing landscape by enabling brands to engage relevant providers during key decision points in patient care.

Data, privacy, and measurement

OptimizeRx emphasizes a commitment to privacy-safe and patient-centric technology. Its Micro-Neighborhood® audiences are described as privacy-compliant, hyper-local consumer audiences created using real-world, privacy-safe clinical and consumer data. The company presents this approach as enabling deterministic cohorts without relying on broad or purely lookalike models. These cohorts are designed to be portable across major media channels and onboarders, allowing life science marketers to activate, manage, and report on omnichannel DTC advertising while maintaining privacy safeguards.

The company also highlights collaborations that connect its audience data with external identity graphs. In these integrations, OptimizeRx’s patented, deterministic Micro-Neighborhood® audience data is mapped to third-party identity infrastructure to support onboarding, curation, and measurement. Reported benefits include more accurate measurement of exposed audiences, reduced audience loss during onboarding, higher projected audience quality, and a reduced gap between projected and actual audience composition for media planning.

Customer base and market orientation

Across its public communications, OptimizeRx describes its primary customers as life science and pharmaceutical manufacturers and healthcare marketing agencies. It reports that it partners with some of the world’s leading pharmaceutical and life sciences companies. The platform is positioned to support these clients in reaching both HCP and DTC audiences, using patient identification technologies and omnichannel networks to help drive faster treatment decisions and improved patient outcomes.

Company materials also reference key performance indicators related to revenue from top pharmaceutical manufacturers, net revenue retention, and revenue per full-time employee. These metrics are used by the company to describe its performance and relationships with large pharmaceutical clients, though specific figures are time-bound and reported in periodic financial releases rather than as permanent characteristics.

Corporate structure and listing

OptimizeRx Corporation is incorporated in Nevada and files periodic reports and current reports with the U.S. Securities and Exchange Commission under Commission File Number 001-38543. The company’s common stock trades on Nasdaq under the ticker symbol OPRX. SEC filings and company press releases identify its headquarters as being located in Waltham, Massachusetts.

Role within healthcare technology and marketing

Within the broader healthcare technology and life sciences marketing space, OptimizeRx positions itself around three main themes drawn from its disclosures: point-of-care engagement, omnichannel audience activation, and privacy-safe, data-driven targeting. Its point-of-care capabilities are built on integrations with EHR and eRx systems and health system partners. Its omnichannel activation is supported by DAAP and Micro-Neighborhood® or MNT audience tools that are designed to work across digital and offline media. Its privacy orientation is reflected in repeated references to privacy-safe, patient-centric technology and the use of real-world clinical data in a compliant manner.

For investors and observers, these elements frame OptimizeRx as a company focused on connecting life sciences brands with clinically relevant audiences at multiple touchpoints, from in-workflow provider interactions to consumer-facing media. The company’s own descriptions highlight its emphasis on measurable engagement, audience quality, and alignment with real-world healthcare data as key aspects of its value proposition.

Stock Performance

$8.76
+1.04%
+0.09
Last updated: November 6, 2026 at 16:00
-53.7%
Performance 1 year
$165.0M

OptimizeRx Corporation (OPRX) closed at $8.76 on November 6, 2026. Over the past 12 months, the price has lost 53.7%.

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OPRX Metrics & Rankings

Price returns through November 6, 2026. Month and year figures include the first trading day. Ranking links may use different dates.

Financial Highlights

OptimizeRx Corporation generated $109.4M in revenue in FY2025, retaining a 67.3% gross margin, operating income reached $11.7M (10.7% operating margin), and net income was $5.1M, reflecting a 4.7% net profit margin. Diluted earnings per share stood at $0.27. The company generated $18.7M in operating cash flow. The current ratio was 3.04, measuring current assets divided by current liabilities.

$109.4M
Revenue (FY2025)
$5.1M
Net Income (FY2025)
$18.7M
Operating Cash Flow

Upcoming Events

NOV
11
November 11, 2026 Earnings

Q3 2026 Earnings Release

Q3 2026 financial results for the quarter ended Sep 30, 2026 will be released before the Nov 11 conference call; timing TBD.
NOV
11
November 11, 2026 Earnings

Q3 2026 Earnings Call

Conference call for Q3 2026 results on Nov 11 at 4:30 p.m. ET hosted by management with a Q&A; webcast details to be provided.
JAN
01
January 1, 2027 Corporate

CFO appointment

Andy D’Silva appointed as Chief Financial Officer effective 2027-01-01 to lead finance and strategy transition.
YEAR
2027
2027 Corporate

Strategic advisor term

Ed Stelmakh to serve as Strategic Advisor from 2027-01-01 through 2027-12-31 to support continuity post-transition.

OptimizeRx Corporation has 4 upcoming scheduled events. The next event, "Q3 2026 Earnings Release", is scheduled for November 11, 2026 (in 3 days). 2 of them are earnings releases or calls. Investors can track these dates to stay informed about potential catalysts that may affect the OPRX stock price.

Short Interest History

Last 12 Months

Short interest in OptimizeRx Corporation (OPRX) currently stands at 1.1 million shares, down 3.4% from the previous reporting period, representing 6.7% of the float. Since November 2025, short interest has decreased by 36.4%.

Days to Cover History

Last 12 Months

Days to cover for OptimizeRx Corporation (OPRX) currently stands at 6.7 days, up 16.5% from the previous period. The ratio is the reported short interest divided by the average daily trading volume. Since November 2025, the figure has increased by 60.8%. Across the settlements charted above, it has ranged from 1.8 to 9.3 days.

OPRX Company Profile & Sector Positioning

OptimizeRx Corporation (OPRX) operates in the Health Information Services industry within the broader Healthcare sector and is listed on the NASDAQ.

Investors comparing OPRX often look at related companies in the same sector, including American Well Corporation (AMWL), So-Young International Inc. (SY), Definitive Healthcare Corp. (DH), Spok Holdings, Inc (SPOK), and Health Catalyst, Inc (HCAT). Comparing financial metrics, valuation ratios, and stock performance across these peers can help investors evaluate OPRX's relative position within its industry.

Frequently Asked Questions

The current stock price of OptimizeRx Corporation (OPRX) is $8.76 as of November 6, 2026.

The market cap of OptimizeRx Corporation (OPRX) is approximately $165.0M. Learn more about what market capitalization means .

The FY2025 revenue of OptimizeRx Corporation (OPRX) is $109.4M, from its most recent completed fiscal year.

The FY2025 net income of OptimizeRx Corporation (OPRX) is $5.1M, from its most recent completed fiscal year.

The diluted earnings per share (EPS) of OptimizeRx Corporation (OPRX) is $0.27 for FY2025, its most recent completed fiscal year. Learn more about EPS .

The operating cash flow of OptimizeRx Corporation (OPRX) is $18.7M for FY2025, its most recent completed fiscal year. Learn about cash flow.

The net profit margin of OptimizeRx Corporation (OPRX) is 4.7% for FY2025, its most recent completed fiscal year. Learn about profit margins.

The operating profit margin of OptimizeRx Corporation (OPRX) is 10.7% for FY2025, its most recent completed fiscal year. Learn about operating margins.

The gross profit margin of OptimizeRx Corporation (OPRX) is 67.3% for FY2025, its most recent completed fiscal year. Learn about gross margins.

The current ratio of OptimizeRx Corporation (OPRX), current assets divided by current liabilities, was 3.04 at the end of FY2025, its most recent completed fiscal year. Learn about liquidity ratios.

The gross profit of OptimizeRx Corporation (OPRX) is $73.6M for FY2025, its most recent completed fiscal year.

The operating income of OptimizeRx Corporation (OPRX) is $11.7M for FY2025, its most recent completed fiscal year. Learn about operating income.

OptimizeRx Corporation is a healthcare technology company that helps life science brands connect with patients and healthcare professionals. According to its public disclosures, the company provides a platform that combines AI-driven tools, point-of-care integrations, and proprietary audience data to support engagement and marketing for pharmaceutical and life sciences organizations.

Company materials state that OptimizeRx works with life science and pharmaceutical manufacturers to reach and engage healthcare professionals and patients. It does this through in-workflow point-of-care messaging in electronic health records and e-prescribing platforms, as well as through audience activation tools that enable omnichannel campaigns aligned with real-world clinical data and brand eligibility signals.

OptimizeRx describes the Dynamic Audience Activation Platform (DAAP) as an AI-driven tool within its platform. DAAP is used to help life science brands identify and activate relevant audiences, supporting timely and contextually appropriate engagement with patients and healthcare providers across multiple media channels.

Micro-Neighborhood® audiences and Micro-Neighborhood Targeting (MNT) are proprietary audience tools that OptimizeRx describes as privacy-compliant, hyper-local consumer cohorts created using real-world, privacy-safe clinical and consumer data. These deterministic cohorts are aligned to brand eligibility signals and can be activated across major media channels, including digital and out-of-home advertising, at granular geographic levels such as ZIP+4 or ZIP+9.

The company reports that it maintains an in-workflow point-of-care network through partnerships with electronic health record (EHR) systems, e-prescribing (eRx) platforms, and health system access partners. These integrations allow life science brands to deliver financial messaging, brand and clinical messaging, brand support, and patient engagement content directly within clinical workflows, including at the point of prescribing and discharge.

OptimizeRx states that it is headquartered in Waltham, Massachusetts, and its common stock is listed on Nasdaq under the ticker symbol OPRX. The company is incorporated in Nevada and files reports with the U.S. Securities and Exchange Commission under Commission File Number 001-38543.

Company descriptions emphasize that OptimizeRx’s technology is privacy-safe and patient-centric. Its Micro-Neighborhood® audiences are described as privacy-compliant and based on real-world, privacy-safe clinical and consumer data. The company highlights that its methods are designed to support deterministic targeting and measurement while maintaining privacy protections for patients and consumers.

OptimizeRx reports that partnerships are central to its model. It has multi-year agreements and renewals with EHR and e-prescribing platforms, health systems access partners, and media companies. These relationships expand its point-of-care network, increase National Provider Identifier reach, and allow its audience data to be integrated with external identity graphs and media inventories for onboarding, curation, and measurement of campaigns.

Based on its public communications, OptimizeRx’s primary customers are life science and pharmaceutical manufacturers and healthcare marketing agencies. The company states that it partners with some of the world’s leading pharmaceutical and life sciences companies to support HCP and DTC engagement using its platform and data assets.

OptimizeRx states that its platform is designed to help life science brands create synchronized marketing solutions that drive faster treatment decisions and improved patient outcomes. By combining point-of-care messaging, AI-driven audience tools, and privacy-safe data, the company aims to deliver life-changing therapies to appropriate patients at the right time.