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Oric Pharmaceuticals Stock Price, News & Analysis

ORIC NASDAQ

Company Description

Company Overview

ORIC Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company dedicated to the discovery and development of innovative therapies that target and overcome resistance mechanisms in cancer. With a strategic emphasis on precision oncology and hormone-dependent cancers, ORIC leverages advanced small molecule science to address some of the most challenging aspects of cancer treatment. The company’s robust pipeline capitalizes on understanding cancer-specific vulnerabilities and offers potential treatments for a variety of solid tumors.

Core Therapeutic Focus

At its core, ORIC concentrates on developing therapies that interfere with key cancer resistance pathways. The company explores multiple mechanisms, including those related to hormone dependency and the tumor microenvironment, to provide solutions where traditional treatments may fail. By focusing on small molecule inhibitors, ORIC aims to disrupt the molecular targets that enable cancer cells to evade chemotherapy and immunotherapy responses.

Innovative Drug Development

The company’s research and development strategy is anchored in rigorous scientific exploration and precision-based drug design. ORIC adopts a multi-faceted approach that includes:

  • Small Molecule Inhibition: Development of orally bioavailable agents that target specific pathways, such as the glucocorticoid receptor and CD73, known to drive resistance in cancer.
  • Precision Oncology: Focusing on therapies that cater to unique genetic and molecular profiles of tumors, enabling targeted intervention in both systemic and intracranial disease manifestations.
  • Integrated R&D Collaborations: Engaging with partners that provide advanced discovery platforms, including AI-driven and structure-based machine learning tools, to accelerate the identification of viable therapeutic candidates.

Pipeline and Research Initiatives

ORIC’s drug development portfolio includes several product candidates that exemplify its expertise in targeting cancer resistance. The pipeline is designed to address various mechanisms by which cancers become refractory to conventional therapies. Some key aspects of the pipeline include:

  • Resistance Targeting: Agents designed to overcome resistance by selectively inhibiting factors involved in treatment evasion, thus restoring or enhancing the efficacy of existing treatments.
  • Oral Bioavailability: An emphasis on creating small molecule candidates with the convenience and compliance benefits of oral dosing, which is critical in chronic treatment settings.
  • Precision and Selectivity: The development of agents with focused activity profiles to maximize clinical benefit while minimizing off-target effects, an essential balance in oncology drug development.

Strategic Collaborations and Technological Integration

ORIC positions itself at the forefront of oncology research by partnering with technology innovators to complement its scientific capabilities. Recent collaborations integrate AI-enabled discovery platforms and structure-based machine learning to enhance early-stage drug discovery. This alliance supports the identification of novel small molecule chemotypes by combining ORIC's deep understanding of cancer biology with advanced computational techniques. Such strategic collaborations illustrate the company’s commitment to applying modern technological tools to solve complex biological challenges, further distinguishing its approach in a competitive therapeutic landscape.

Market Position and Industry Dynamics

The company operates within the highly competitive biopharmaceutical sector, where innovation, clinical rigor, and specialized knowledge are pivotal. ORIC’s focus on countering therapeutic resistance sets it apart within its industry by addressing a clinically significant issue that affects treatment outcomes across multiple cancer types. By concentrating on precision medicine and targeted therapy, the company's approach resonates with evolving trends in oncology research, allowing it to stand as a specialized entity amid larger diversified competitors. This concentrated focus not only enhances its potential for scientific breakthroughs but also reinforces its credibility amongst clinical communities and financial analysts looking for expertise in challenging therapeutic areas.

Commitment to Robust Scientific Inquiry

Every aspect of ORIC’s business model is underpinned by a commitment to rigorous scientific inquiry and detailed molecular analysis. The company’s systematic exploration of cancer resistance pathways underscores its long-standing dedication to advancing the field of oncology through innovative therapeutic interventions. This commitment is reflected in its precision-driven research, transparent exploration of scientific data, and adherence to high standards of clinical evaluation.

Summary

In summary, ORIC Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical firm with a focused mission: to develop advanced treatments that address the fundamental challenge of therapeutic resistance in cancer. By leveraging sophisticated small molecule technologies, forging strategic partnerships, and embedding precision oncology into its core research initiatives, ORIC offers a comprehensive approach to some of the most persistent challenges in cancer therapy. Its methodical and innovative strategy enables it to maintain a specialized niche in a competitive market, making it a critical contributor to the ongoing evolution of cancer treatment paradigms.

Stock Performance

$12.31
-1.91%
0.24
Last updated: November 7, 2025 at 09:54
21.84 %
Performance 1 year

Financial Highlights

$0
Revenue (TTM)
-$127,847,000
Net Income (TTM)
-$112,662,000
Operating Cash Flow
-$142,895,000

Upcoming Events

NOV
11
November 11, 2025 Marketing

Guggenheim one-on-one meetings

One-on-one meetings at Guggenheim 2nd Annual Healthcare Innovation Conference
NOV
11
November 11, 2025 Marketing

Guggenheim fireside chat

Webcast via company investor website; replay available 90 days
NOV
12
November 12, 2025 Marketing

Stifel one-on-one meetings

One-on-one meetings at Stifel 2025 Healthcare Conference
NOV
19
November 19, 2025 Marketing

Jefferies one-on-one meetings

One-on-one meetings at Jefferies London Healthcare Conference
NOV
19
November 19, 2025 Marketing

Jefferies fireside chat

Webcast via company investor website; replay available 90 days
DEC
01
December 1, 2025 Clinical

ESMO Asia 2025 presentation

Presentation of multiple clinical datasets at ESMO Asia 2025
JAN
01
January 1, 2026 Clinical

Initiate ORIC-944 Phase 3 trial

JAN
01
January 1, 2026 Clinical

ORIC-944 Phase 3 initiation

JAN
01
January 1, 2026 Clinical

ORIC-114 registrational start

JAN
01
January 1, 2026 - June 30, 2026 Clinical

Phase 3 trial initiation

Start of first global ORIC-944 Phase 3 registrational trial

Short Interest History

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Frequently Asked Questions

What is the current stock price of Oric Pharmaceuticals (ORIC)?

The current stock price of Oric Pharmaceuticals (ORIC) is $12.55 as of November 6, 2025.

What is the market cap of Oric Pharmaceuticals (ORIC)?

The market cap of Oric Pharmaceuticals (ORIC) is approximately 1.2B. Learn more about what market capitalization means .

What is the revenue (TTM) of Oric Pharmaceuticals (ORIC) stock?

The trailing twelve months (TTM) revenue of Oric Pharmaceuticals (ORIC) is $0.

What is the net income of Oric Pharmaceuticals (ORIC)?

The trailing twelve months (TTM) net income of Oric Pharmaceuticals (ORIC) is -$127,847,000.

What is the earnings per share (EPS) of Oric Pharmaceuticals (ORIC)?

The diluted earnings per share (EPS) of Oric Pharmaceuticals (ORIC) is -$1.83 on a trailing twelve months (TTM) basis. Learn more about EPS .

What is the operating cash flow of Oric Pharmaceuticals (ORIC)?

The operating cash flow of Oric Pharmaceuticals (ORIC) is -$112,662,000. Learn about cash flow.

What is the current ratio of Oric Pharmaceuticals (ORIC)?

The current ratio of Oric Pharmaceuticals (ORIC) is 10.56, indicating the company's ability to pay short-term obligations. Learn about liquidity ratios.

What is the operating income of Oric Pharmaceuticals (ORIC)?

The operating income of Oric Pharmaceuticals (ORIC) is -$142,895,000. Learn about operating income.

What is the core focus of ORIC Pharmaceuticals?

ORIC Pharmaceuticals concentrates on discovering and developing therapies that target and overcome resistance mechanisms in cancer, with a focus on precision oncology and hormone-dependent cancers.

Which therapeutic areas does ORIC emphasize?

The company emphasizes precision medicine, hormone-dependent cancer treatment, and targeting tumor-specific resistance pathways using advanced small molecule inhibitors.

How does ORIC generate revenue?

Revenue generation for ORIC is linked to its drug development pipeline, including licensing of its discoveries and collaborative research partnerships focused on advancing therapeutic candidates.

What differentiates ORIC from its competitors?

ORIC differentiates itself through a dedicated focus on countering therapeutic resistance in cancer, its precision-based approach to drug development, and strategic collaborations that integrate advanced AI-enabled discovery platforms.

What is the significance of ORIC's pipeline?

The pipeline is designed to develop small molecule therapies that address specific cancer resistance mechanisms, demonstrating the company's commitment to tailored, precision-based oncology treatments.

How does ORIC incorporate modern technology into its R&D approach?

ORIC integrates advanced technologies such as structure-based machine learning and AI-enabled discovery platforms to enhance early drug discovery and identify potent therapeutic leads.

What are the primary categories of products being developed by ORIC?

The products under development are small molecule inhibitors aimed at countering resistance pathways, facilitating both systemic and intracranial treatment responses across a spectrum of solid tumors.

How does ORIC's approach impact the overall treatment landscape in oncology?

By addressing mechanisms of therapeutic resistance, ORIC provides potential avenues to enhance the efficacy of existing treatments, thereby offering new hope in challenging cases where standard therapies may be insufficient.