Company Description
OSR Holdings, Inc. (NASDAQ: OSRH) is a global healthcare holding company focused on advancing biomedical innovations in healthcare and wellness. According to the company’s public statements, OSR Holdings operates through subsidiaries engaged in immuno-oncology, regenerative biologics, and medical device technologies, with the goal of improving global health outcomes.
OSR Holdings’ common stock and redeemable warrants trade on The Nasdaq Stock Market LLC under the symbols OSRH and OSRHW, respectively, as disclosed in multiple Form 8-K filings. The company is classified as an emerging growth company under U.S. securities regulations. Its structure as a holding company allows it to acquire, integrate, and oversee specialized healthcare and biotechnology businesses while providing capital markets access and corporate governance at the parent level.
Business focus and subsidiary platforms
Public disclosures describe OSR Holdings as building a portfolio of healthcare and wellness companies. Through its subsidiaries, the company is involved in:
- Immuno-oncology – via Vaximm AG, a Swiss-German biotechnology company that is a wholly owned subsidiary of OSR Holdings. Vaximm develops orally administered T-cell immunotherapies for cancer using a proprietary vaccination platform based on live, attenuated bacterial vectors that deliver tumor-associated antigens. Its lead candidate, VXM01, targets VEGFR-2 and has demonstrated clinical activity and safety in multiple cancer indications, according to company news releases.
- Medical device technologies – via Woori IO Co., Ltd. (Woori IO or WORIO), a South Korea-based medical-device company developing non-invasive biosensing technology for glucose monitoring and related health parameters. OSR Holdings’ Korean affiliate, OSR Holdings Co., Ltd. (OSRK), entered into and later completed a share exchange under which Woori IO became a wholly owned subsidiary of OSRK and indirectly of OSR Holdings. Woori IO focuses on near-infrared spectroscopy (NIRS)-based noninvasive glucose monitoring platforms, including the Glucheck blood glucose measurement system, and is described as a pioneer in noninvasive glucose monitoring.
- Regenerative biologics – OSR Holdings has stated in multiple news releases that its activities include regenerative biologics, although detailed product descriptions are not provided in the available materials.
OSR Holdings has also referenced a broader innovation platform that includes medical device distribution and regenerative medicine, as well as a vision to acquire and operate a portfolio of innovative healthcare and wellness companies.
Immuno-oncology: Vaximm AG and VXM01
Vaximm AG is described as a privately held Swiss-German biotechnology company and a subsidiary of OSR Holdings. Its platform uses orally administered T-cell vaccination based on live, attenuated bacterial vectors to induce cellular immune responses against tumor-associated antigens. The company’s lead candidate, VXM01, targets VEGFR-2 and has shown clinical activity and safety in several cancer indications, including pancreatic cancer and glioblastoma, based on the company’s news disclosures.
OSR Holdings has reported that Vaximm entered into a non-binding global license term sheet with BCM Europe AG (BCME), described as a Swiss-based life sciences investment group and OSRH’s largest shareholder, for a potential exclusive global licensing agreement for VXM01. Subsequent updates indicate that the parties shortened the exclusivity period to three months and then that Vaximm received a binding term sheet from BCM Europe AG (through a dedicated investment vehicle) for a global exclusive license of VXM01, with specified upfront and milestone payment structures and a royalty pass-through mechanism. These proposed transactions are subject to definitive agreements, board review, and customary conditions, and Vaximm has indicated it will obtain an independent third-party fairness opinion regarding the proposed license.
In addition to VXM01, Vaximm has signaled an intent to integrate its oral T-cell immunotherapy platform with complementary viral oncolysis technologies that have achieved clinical proof-of-concept in a completed U.S. FDA Phase 2a study, through a planned strategic collaboration. The stated objective is to build a next-generation immuno-oncology platform for renal cell carcinoma and other advanced solid tumors, combining anti-angiogenic immune activation with other immune-modulating approaches.
Noninvasive glucose monitoring: Woori IO and Glucheck
Woori IO Co., Ltd. is described in OSR Holdings’ filings and press releases as a South Korea-based medical-device company developing non-invasive biosensing technology for glucose monitoring and related health parameters. Its proprietary NIRS platform is intended to enable needle-free continuous glucose monitoring for people with diabetes.
OSR Holdings and its Korean affiliate OSRK entered into a term sheet and then a definitive Share Exchange Agreement with Woori IO, under which Woori IO would become, and subsequently became, a wholly owned subsidiary of OSRK and indirectly of OSR Holdings. The agreement describes Woori IO’s work under a Non-invasive Blood Glucose Monitor Proof-of-Concept Development Services Agreement with Samsung Electronics, under which Samsung provided non-dilutive funding for proof-of-concept trials of Woori IO’s NIRS technologies.
OSR Holdings has also disclosed results from a company-sponsored pilot study of Woori IO’s Glucheck blood glucose measurement system, conducted with Korea University Guro Hospital. The study evaluated mouse-type and stick-type Glucheck models against a reference chemistry analyzer, reporting high accuracy, strong precision, robust correlation, and compliance with ISO 15197:2013 acceptance criteria, based on the company’s summary. These data are presented as a technical milestone supporting further proof-of-concept and regulatory trials, including ongoing collaboration with Samsung and plans for a Korean MFDS-compliant clinical trial at a leading Seoul medical center.
Corporate structure, capital markets, and governance
OSR Holdings is incorporated in Delaware and has its principal executive offices in Bellevue, Washington, as reflected in its proxy statement and multiple Form 8-K filings. The company’s securities—common stock and redeemable warrants—are listed on the Nasdaq Capital Market under the symbols OSRH and OSRHW. The company has identified itself as an emerging growth company in several SEC filings.
OSR Holdings has used various capital markets instruments to support its operations and growth, including:
- A Note Purchase Agreement and related Common Stock Purchase Warrant with White Lion Capital, LLC, later amended to address shareholder approvals and Nasdaq exchange cap considerations.
- An Equity Line of Credit Agreement referenced in connection with shareholder approval proposals in the company’s proxy materials.
- Share-based incentive sub-plans under a 2025 Omnibus Incentive Plan, subject to shareholder approval as described in the definitive proxy statement.
The company’s proxy materials describe proposals related to director elections, executive compensation on an advisory basis, equity plan approvals, and authorization under Nasdaq Listing Rule 5635(d) for potential issuances of common stock or convertible securities in amounts that could exceed 20% of the then-outstanding shares in certain non-public offerings.
Regulatory status and Nasdaq listing
OSR Holdings has disclosed that it received a Nasdaq minimum bid price deficiency notice under Listing Rule 5550(a)(2) after its common stock traded below $1.00 per share for 30 consecutive business days. The notice grants an initial 180-day period to regain compliance, with the possibility of an additional period if certain conditions are met. The company has stated that the notice does not immediately affect the listing or trading of its securities, which continue to trade on the Nasdaq Capital Market under OSRH and OSRHW.
In response to share price volatility and settlement imbalances, OSR Holdings has publicly noted elevated fails-to-deliver data and expressed concern that such patterns may indicate manipulative short selling practices, while emphasizing its focus on advancing scientific programs, digital asset treasury strategies, and potential acquisitions such as Woori IO.
Strategic themes and innovation approach
Across its news releases, OSR Holdings presents several recurring themes:
- Portfolio-building in healthcare and wellness – The company describes a vision of acquiring and operating a portfolio of innovative healthcare and wellness companies, with an emphasis on immuno-oncology, regenerative biologics, and medical device technologies.
- Digital asset and tokenization strategies – OSR Holdings references a Digital Asset Treasury (DAT) strategy intended to support financial flexibility. In the context of Vaximm’s potential licensing of VXM01, the company has described an optional blockchain-based royalty participation mechanism using “TAC” tokens to represent potential future royalty streams, through a BCM Royalty Fund structure.
- Structured licensing and royalty financing – The contemplated VXM01 licensing arrangements with BCM Europe AG and related funds are described as structured financing models that position an intermediary to fund development in exchange for future royalties and milestone-based returns, with pass-through royalty mechanisms to Vaximm.
OSR Holdings also organizes virtual investor events and conference presentations to provide updates on corporate strategy, subsidiary performance, capital allocation, and research and development pipelines, including programs at Vaximm, regenerative biologics initiatives such as Darnatein’s DRT101 (as referenced in event agendas), and the Woori IO acquisition opportunity.
Exchange-traded securities
According to multiple Form 8-K filings, OSR Holdings has the following classes of securities registered under Section 12(b) of the Securities Exchange Act of 1934:
- Common stock, par value $0.0001 per share, trading under the symbol OSRH on The Nasdaq Stock Market LLC.
- Redeemable warrants, exercisable for shares of common stock at an exercise price of $11.50 per share, trading under the symbol OSRHW on The Nasdaq Stock Market LLC.
FAQs
The following questions and answers summarize key aspects of OSR Holdings, Inc. based on available public information.