Company Description
Repligen Corporation (NASDAQ: RGEN) is a global life sciences company focused on bioprocessing technology leadership. According to the company’s disclosures, Repligen develops and commercializes bioprocessing technologies and systems that enable efficiencies in the process of manufacturing biological drugs. The company describes its mission as “inspiring advances in bioprocessing” for the customers it serves worldwide.
Repligen is headquartered in Waltham, Massachusetts, and its common stock is listed on the Nasdaq Global Select Market under the symbol RGEN. The company reports that the majority of its manufacturing sites are in the United States, with additional key sites in Estonia, France, Germany, Ireland, the Netherlands and Sweden. This footprint supports a global customer base in the biopharmaceutical and life sciences industries.
Business focus and customer base
Repligen states that it serves primarily biopharmaceutical drug developers and contract development and manufacturing organizations (CDMOs). Its technologies are used in the manufacturing of biological drugs, and the company emphasizes enabling process efficiencies for these customers. Repligen’s public materials consistently highlight bioprocessing as its core area of activity within the broader life sciences sector.
According to the company description provided in its news releases, Repligen’s focus areas are:
- Filtration and Fluid Management
- Chromatography
- Process Analytics
- Proteins
These focus areas are presented as the main categories of its bioprocessing technologies and systems. The company also refers to a portfolio of products and systems that support process development and manufacturing for biological drugs.
Products and technology areas
Repligen’s own descriptions indicate that its technologies are used in bioprocessing workflows for biological drugs. In a Polygon description, Repligen is described as developing and selling bioprocessing equipment and supplies used in the manufacturing of biologic drugs, including monoclonal antibodies, recombinant proteins, vaccines, and cell and gene therapies. That description also notes four main product categories: filtration (including fluid management), chromatography, proteins, and process analytics.
In a company press release announcing new chromatography resins, Repligen describes the launch of three high-performance chromatography resins in its proteins portfolio, intended to support new modality workflows. The company states that these resins are designed to help gene therapy developers accelerate product development, improve molecule stability, and enhance process economics. This illustrates how Repligen positions its technologies within evolving bioprocessing needs, including applications in viral vector and gene therapy manufacturing.
Repligen also highlights process analytics and tangential flow filtration (TFF) systems as part of its technology base. In a press release about a strategic partnership with Novasign, Repligen notes that Novasign’s machine learning and modeling workflow will be integrated into Repligen filtration systems, and that this will strengthen its portfolio of process analytical technology (PAT)-enabled systems. The company describes this as part of a broader digitalization journey aimed at enabling smart digital manufacturing in bioprocessing.
Geographic footprint and operations
Across multiple news releases, Repligen states that its corporate headquarters are located in Waltham, Massachusetts. It further notes that the majority of its manufacturing sites are in the United States, with additional key sites in Estonia, France, Germany, Ireland, the Netherlands and Sweden. These disclosures indicate a manufacturing and operational presence across North America and Europe to support its global life sciences customer base.
The Polygon description also notes that customers in North America, Europe, and Asia Pacific contribute to Repligen’s revenue, indicating that the company serves customers across these regions. While specific revenue percentages are given in that description, those figures are tied to a particular period and are therefore not repeated here. The geographic references, however, provide context for the company’s global reach.
Financial reporting and public company status
Repligen files regular reports with the U.S. Securities and Exchange Commission (SEC) as a public company. Recent Form 8-K filings reference the announcement of financial results for the second and third quarters of 2025, as well as updates to full-year 2025 financial guidance. These filings confirm that Repligen provides detailed financial information, including revenue, margins, and non-GAAP measures, through its earnings press releases and associated SEC disclosures.
In its earnings releases, Repligen describes its business in terms of franchises such as consumables and capital equipment, and discusses demand trends from biopharma and CDMO customers. The company also outlines its use of non-GAAP financial measures, such as adjusted gross profit, adjusted income from operations, and adjusted EBITDA, explaining that these are intended to supplement GAAP results.
Corporate governance and leadership developments
Repligen’s recent news includes updates related to corporate governance and leadership roles. In a January 2026 press release, the company announced that its Board of Directors elected Dr. Martin D. Madaus as Chair of the Board, effective March 13, 2026, and that Tony Hunt would retire from his role as Executive Chair and member of the Board on that date, while continuing to serve as an advisor to Repligen through March 2027. The same press release includes statements from Repligen’s President and CEO and from Dr. Madaus and Mr. Hunt regarding the transition.
In a September 2025 Form 8-K, Repligen reported the appointment of a Chief Accounting Officer, noting that the role is intended to build a more robust infrastructure for financial reporting and oversight of matters related to the Sarbanes–Oxley Act. The filing describes the appointee’s background in financial controllership and governance across life sciences and related industries, and outlines elements of the compensation package approved by the company’s Compensation Committee.
Strategic initiatives and partnerships
Repligen’s news releases describe several strategic activities that relate to its position in bioprocessing. In its second and third quarter 2025 earnings releases, the company highlights growth across its franchises and geographies, as well as the performance of consumables and capital equipment. It also notes product launches, such as a single-use mixer based on Metenova’s mixing technology, and references a sustainability report that discusses environmental, social and governance initiatives.
In July 2025, Repligen announced a strategic partnership with Novasign to integrate Novasign’s machine learning and modeling workflow into Repligen’s tangential flow filtration systems. The company states that the goal of this collaboration is to streamline process development, enable real-time predictive control, and reduce development timelines and costs through digital twins and advanced modeling. Repligen characterizes this partnership as an important step in advancing bioprocess digitalization and smart manufacturing.
Industry classification
Repligen is classified in the Biological Product (except Diagnostic) Manufacturing industry within the Manufacturing sector. Its own descriptions consistently refer to it as a global life sciences company focused on bioprocessing technologies and systems for biological drug manufacturing. This places Repligen within the bioprocessing and biomanufacturing tools segment of the life sciences industry.
Use of non-GAAP measures
In its earnings releases, Repligen explains that it uses various adjusted (non-GAAP) financial measures, including organic revenue and organic revenue growth, adjusted gross margin, adjusted operating margin, adjusted net income, and adjusted EBITDA. The company states that these measures exclude items such as acquisition and integration costs, restructuring charges, inventory step-up costs, CEO transition costs, contingent consideration adjustments, intangible amortization, certain non-cash interest expense, and foreign currency impacts on certain intercompany loans, along with related tax effects. Repligen notes that reconciliations of GAAP to non-GAAP figures are provided in tables included with its earnings releases.
RGEN stock overview
Repligen’s common stock trades on the Nasdaq Global Select Market under the ticker symbol RGEN. The company’s SEC filings confirm that its common stock has a par value of $0.01 per share. As a publicly traded life sciences company, Repligen’s stock is influenced by factors such as demand for bioprocessing technologies, financial performance, product development, strategic partnerships, and broader conditions in the biopharmaceutical and life sciences markets, as reflected in its public disclosures.
Key themes in Repligen’s public communications
Across its news releases and filings, several themes recur in Repligen’s self-description:
- A focus on bioprocessing technologies and systems that support the manufacturing of biological drugs.
- Service to biopharmaceutical drug developers and CDMOs as primary customer groups.
- Emphasis on Filtration and Fluid Management, Chromatography, Process Analytics and Proteins as core focus areas.
- Commitment to bioprocessing efficiency and, in some communications, to advancing bioprocess digitalization through partnerships and technology integration.
- Operation as a global life sciences company with headquarters in Waltham, Massachusetts, and manufacturing sites in the U.S. and several European countries.
Investors and observers can obtain more detailed and time-specific information about Repligen’s financial results, product launches, partnerships, and governance developments by reviewing the company’s SEC filings and official press releases, some of which are summarized in the recent news and filings referenced here.