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Top Performing Stocks 2022 - Year-to-Date Gainers Ranked

Discover the best US stocks of 2022 ranked by year-to-date performance. This ranking tracks YTD gains and highest YTD returns from January 1st, 2022 to today, featuring the top stock gainers with market caps over $100 million on Nasdaq and NYSE.

This ranking shows the top performing US stocks and biggest stock gainers of 2022, calculated from January 1st to the most recent trading day. See which stocks delivered the highest YTD returns this year. Using split-adjusted data ensures accurate performance calculations that account for stock splits and corporate actions.

Year-to-date performance helps investors identify stocks that have been outperforming the market in the current year, revealing trends and momentum that may continue through the rest of 2022.

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Data as of April 27, 2026 at 4:54 AM EDT

Rank
Symbol
Company Name
YTD Gain
Market Cap
Price
Country
Sector
3701
-94.17%
408.45 M
$ 5.65
United States
Technology
3702
-94.25%
1.34 B
$ 8.22
United States
Healthcare
3703
-94.35%
674.58 M
$ 13.81
United States
Healthcare
3704
-94.38%
149.75 M
$ 3.9
United States
Healthcare
3705
-94.44%
414.85 M
$ 3.46
United States
Technology
3706
-94.47%
126.01 M
$ 1.46
United States
Industrials
3707
-94.48%
117.27 M
$ 0.9389
United States
Healthcare
3708
-94.69%
373.68 M
$ 4.11
United States
Healthcare
3709
-94.83%
123.00 M
$ 11.15
United States
Consumer Cyclical
3710
-94.84%
123.40 M
$ 7.91
United States
Communication Services
3711
-94.95%
397.29 M
$ 5.95
United States
Technology
3712
-95.08%
282.31 M
$ 3.98
United States
Healthcare
3713
-95.22%
185.91 M
$ 12.89
United States
Healthcare
3714
-95.27%
459.97 M
$ 8.48
United States
Real Estate
3715
-95.47%
123.58 M
$ 0.9757
United States
Technology
3716
-95.77%
269.86 M
$ 8.83
United States
Technology
3717
-95.86%
247.37 M
$ 3.52
United States
Healthcare
3718
-96.11%
1.14 B
$ 17.12
United States
Technology
3719
-96.22%
436.65 M
$ 26.21
United States
Healthcare
3720
-96.38%
107.57 M
$ 1.02
United States
Healthcare
3721
-96.44%
155.08 M
$ 28.19
United States
Technology
3722
-96.47%
108.70 M
$ 0.8507
United States
Consumer Defensive
3723
-96.52%
145.87 M
$ 0.6722
United States
Healthcare
3724
-96.56%
301.77 M
$ 2.37
United Kingdom
Industrials
3725
-96.58%
101.55 M
$ 1.38
United States
Healthcare
3726
-96.61%
150.69 M
$ 3.1
United States
Technology
3727
-96.69%
115.15 M
$ 1.03
United States
Consumer Defensive
3728
-96.98%
181.65 M
$ 7.04
United States
Healthcare
3729
-97.06%
165.72 M
$ 4.94
United States
Consumer Cyclical
3730
-97.07%
112.81 M
$ 0.7881
United States
Industrials
3731
-97.14%
140.09 M
$ 12.26
Australia
Healthcare
3732
-97.17%
227.42 M
$ 14.53
United Kingdom
Technology
3733
-97.28%
229.34 M
$ 4.34
United Kingdom
Technology
3734
-97.49%
179.52 M
$ 0.6285
United States
Energy
3735
-97.74%
487.34 M
$ 7.87
United States
Healthcare
3736
-97.78%
1.44 B
$ 7.31
United States
Financial Services
3738
-97.79%
154.63 M
$ 1.33
United States
Healthcare
3737
-97.79%
109.95 M
$ 0.8646
United States
Technology
3739
-97.86%
106.84 M
$ 2.08
Belgium
Healthcare
3740
-97.86%
134.91 M
$ 1.7
United States
Industrials
3741
-98.15%
610.13 M
$ 2.91
China
Consumer Cyclical
3742
-98.27%
168.23 M
$ 6.89
United States
Consumer Cyclical
3743
-98.46%
371.77 M
$ 10.84
United States
Consumer Cyclical
3744
-98.47%
2.29 B
$ 6.25
United States
Consumer Cyclical
3745
-98.65%
404.87 M
$ 0.8734
United States
Consumer Defensive
3746
-98.67%
112.92 M
$ 1.16
United States
Energy
3747
-98.69%
114.42 M
$ 1.5
United States
Healthcare
3748
-98.73%
501.04 M
$ 1.185
Canada
Healthcare
3749
-98.87%
217.99 M
$ 9.916
China
Communication Services
3750
-99.05%
243.59 M
$ 2.58
United States
Industrials
3751
-99.19%
368.59 M
$ 14.3
United States
Healthcare
3752
-99.38%
955.79 M
$ 1.64
United States
Communication Services
3753
-99.55%
137.02 M
$ 1.2
United States
Financial Services
3754
-99.68%
268.92 M
$ 3.42
United States
Industrials
3755
-99.73%
317.22 M
$ 13.92
United States
Healthcare
3756
-99.8%
126.50 M
$ 0.1361
United States
Healthcare
3757
-99.82%
348.65 M
$ 2.08
United States
Healthcare
3758
-99.93%
3.41 B
$ 15.39
United States
Financial Services
3760
-100%
118.87 M
$ 2.16
United States
Financial Services
3759
-100%
179.13 M
$ 12.61
United States
Healthcare
For the most accurate results, consider cross-referencing our data with other sources.