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#1 MNPR leads with +5,186% 2024 YTD

MNPR (Monopar Therapeutics Inc.) is the best performing stock in 2024 year-to-date. Following are SEZL (+5,038%) and DAVE (+4,394%). Top performing sectors: Financial Services (+1648% avg, 1 in top 10), Technology (+1170% avg, 5 in top 10), Healthcare (+1134% avg, 3 in top 10).

Top Performing Stocks 2024 - Year-to-Date Gainers Ranked

Discover the best US stocks of 2024 ranked by year-to-date performance. This ranking tracks YTD gains and highest YTD returns from January 1st, 2024 to today, featuring the top stock gainers with market caps over $100 million on Nasdaq and NYSE.

This ranking shows the top performing US stocks and biggest stock gainers of 2024, calculated from January 1st to the most recent trading day. See which stocks delivered the highest YTD returns this year. Using split-adjusted data ensures accurate performance calculations that account for stock splits and corporate actions.

Year-to-date performance helps investors identify stocks that have been outperforming the market in the current year, revealing trends and momentum that may continue through the rest of 2024.

Looking for a specific Symbol?

Data as of July 4, 2026 at 8:32 AM EDT

Rank
Symbol
Company Name
YTD Gain
Market Cap
Price
Country
Sector
1
5185.95%
636.61 M
$ 95.03
United States
Healthcare
2
5037.52%
5.89 B
$ 175.18
United States
Financial Services
3
4393.74%
4.87 B
$ 383.13
United States
Technology
4
3766.85%
330.71 M
$ 11.78
United States
Technology
5
3576.71%
652.89 M
$ 66.54
United States
Healthcare
6
3490.53%
300.95 B
$ 2032.22
United States
Technology
7
2849.58%
1.14 B
$ 7.7
United States
Basic Materials
8
2640.54%
8.71 B
$ 23.5
United States
Technology
9
2457.2%
2.13 B
$ 71.71
United States
Healthcare
10
2192.31%
4.25 B
$ 65.03
United States
Technology
11
2049.08%
1.03 B
$ 74.61
Hong Kong
Technology
12
1840.72%
6.21 B
$ 18.68
United States
Technology
13
1791.9%
62.53 B
$ 100.07
United States
Industrials
14
1772.73%
846.41 M
$ 36.72
United States
Industrials
15
1735.3%
82.35 B
$ 289.5
United States
Industrials
16
1655.26%
33.42 B
$ 86.1
United States
Technology
17
1564.44%
2.61 B
$ 13.27
United States
Healthcare
18
1424.02%
8.91 B
$ 319.6
United States
Healthcare
19
1395.76%
9.90 B
$ 706.15
United States
Industrials
20
1299.54%
62.33 B
$ 801.16
United States
Technology
21
1279.23%
2.50 B
$ 17.61
United States
Healthcare
22
1259.1%
189.67 B
$ 564.61
United States
Communication Services
23
1239.35%
11.54 B
$ 144.65
France
Healthcare
24
1218.49%
11.27 B
$ 31.61
United States
Industrials
25
1216.16%
48.31 B
$ 259.09
Cayman Islands
Technology
26
1170.79%
1.11 B
$ 6.36
Canada
Basic Materials
27
1128.24%
1.61 B
$ 10.55
United States
Industrials
28
1111.95%
2.33 B
$ 37.24
United States
Healthcare
29
1089.28%
41.58 B
$ 361.62
Canada
Technology
30
1084.79%
1.17 T
$ 1032.28
United States
Technology
31
1050.99%
997.72 M
$ 15.89
United States
Technology
32
1043.88%
1.98 B
$ 138.26
United States
Healthcare
33
959.77%
206.25 B
$ 598.37
United States
Technology
34
912.73%
526.21 M
$ 5.195
United States
Technology
35
911.74%
2.13 B
$ 9.43
United States
Technology
36
902.44%
18.66 B
$ 179.7
United States
Technology
37
901%
285.21 M
$ 19.69
United States
Financial Services
38
891.85%
207.06 B
$ 915.19
Singapore
Technology
39
840.82%
1.67 B
$ 9.7
Canada
Technology
40
835.89%
65.46 B
$ 462.44
United States
Technology
41
820.87%
11.68 B
$ 23.58
United States
Financial Services
42
815.5%
2.11 B
$ 23.07
United States
Basic Materials
43
811.32%
97.84 B
$ 108.65
United States
Financial Services
44
784.21%
2.36 B
$ 72.23
United States
Technology
45
766.47%
285.83 M
$ 6.05
United States
Technology
46
765.34%
1.24 B
$ 14.76
United States
Healthcare
47
761.69%
65.62 B
$ 1865.15
United States
Industrials
48
761.07%
30.32 B
$ 610.16
United States
Industrials
49
751.15%
5.57 B
$ 17.92
United States
Healthcare
50
749%
4.20 B
$ 79.51
United States
Industrials
51
744.52%
13.95 B
$ 699.98
United States
Industrials
52
729.66%
3.24 B
$ 20.2
United States
Industrials
53
725.29%
23.83 B
$ 776.55
United States
Industrials
54
723.93%
4.93 B
$ 90.21
United States
Healthcare
55
718.01%
9.65 B
$ 264.86
United States
Industrials
56
716.99%
1.00 B
$ 36.63
United States
Healthcare
57
698.64%
1.90 B
$ 12.74
United States
Industrials
58
697.47%
588.38 M
$ 3.41
Canada
Basic Materials
59
696.23%
2.18 B
$ 64.39
United States
Healthcare
60
695.08%
304.82 B
$ 1134.35
United States
Industrials
61
691.45%
72.12 B
$ 368.65
United States
Technology
62
691.26%
1.60 B
$ 4.74
Canada
Basic Materials
63
679.86%
301.41 B
$ 125.73
United States
Technology
64
670.95%
11.91 B
$ 105.79
United States
Financial Services
65
652.49%
7.24 B
$ 31.26
United States
Consumer Cyclical
66
652.48%
3.23 B
$ 25.84
United States
Healthcare
67
639%
5.65 B
$ 34.65
United States
Basic Materials
68
638.04%
444.36 M
$ 17.94
United States
Technology
69
630.38%
5.10 B
$ 104.49
United States
Healthcare
70
628.71%
1.11 B
$ 23.22
United States
Technology
71
624.53%
2.07 B
$ 7.93
United States
Healthcare
72
623.18%
29.21 B
$ 245.46
Israel
Technology
73
611.67%
1.71 B
$ 10.17
Hong Kong
Technology
74
607.56%
161.16 M
$ 16.3
United States
Technology
75
601.86%
74.44 B
$ 67.87
United States
Consumer Cyclical
76
597.06%
3.82 B
$ 60.02
United States
Technology
77
584.56%
7.05 B
$ 79.32
United States
Healthcare
78
581.01%
328.85 M
$ 87.83
United States
Technology
79
578.69%
9.12 B
$ 15.77
Canada
Basic Materials
80
577.93%
723.91 M
$ 9.88
United States
Healthcare
81
574.01%
15.96 B
$ 350.21
United States
Technology
82
570.35%
39.86 B
$ 187.51
United States
Healthcare
83
567.65%
1.44 B
$ 13.79
United States
Healthcare
84
565.74%
1.82 B
$ 14.09
Australia
Healthcare
85
564.42%
153.29 M
$ 24.51
United States
Industrials
86
564.11%
2.34 B
$ 44.02
United States
Healthcare
87
558.48%
119.62 B
$ 311.42
United States
Industrials
88
556.99%
1.62 B
$ 23.98
United States
Technology
89
555.2%
73.85 B
$ 430.86
United States
Technology
90
555.1%
1.31 B
$ 190.71
United States
Healthcare
91
550.3%
2.63 B
$ 20.99
United States
Basic Materials
92
550%
375.26 M
$ 20.5
United States
Technology
93
547.14%
9.71 B
$ 120.95
United States
Technology
94
545.42%
189.88 B
$ 220.63
United States
Technology
95
539.78%
303.30 M
$ 5.95
United States
Communication Services
96
533.65%
22.64 B
$ 170.77
United States
Healthcare
97
529.41%
2.56 B
$ 9.18
United States
Industrials
98
527.55%
13.71 B
$ 69.85
United States
Healthcare
99
526.07%
2.02 B
$ 43.81
United States
Technology
100
525.09%
13.70 B
$ 147.03
United States
Technology
Return measured from the start of the stock's current trading history (a recent listing or relisting), not from January 1st.
For the most accurate results, consider cross-referencing our data with other sources.

Frequently Asked Questions

Q What is the best stock of 2024?
A

MNPR (Monopar Therapeutics Inc.) is the best performing stock of 2024 with a year-to-date gain of 5,186% from January 1st to today. The top 3 stocks of 2024 are MNPR, SEZL, DAVE.

Q What are the top performing stocks in 2024?
A

The top performing stocks in 2024 YTD are: MNPR (+5,186%), SEZL (+5,038%), DAVE (+4,394%), TSSI (+3,767%), DRUG (+3,577%). Performance is calculated from January 1, 2024 to the most recent trading day.

Q Which stocks have made the most money in 2024?
A

The biggest stock gainers of 2024 include MNPR leading with +5,186%, followed by SEZL (+5,038%) and DAVE (+4,394%). These represent the best investment returns YTD.

Q What sectors are performing best in 2024?
A

In 2024, the best performing sectors based on top stock gains include Healthcare, Financial Services, Technology. The top gainer MNPR operates in the Healthcare sector.

Q Which US stocks have the highest YTD returns in 2024?
A

The US stocks with the highest year-to-date returns in 2024 include MNPR (+5,186%), SEZL (+5,038%), DAVE (+4,394%). These top YTD gainers are ranked by total return from January 1st to today across NYSE and NASDAQ.

Understanding Year-to-Date Stock Performance

Year-to-date (YTD) performance measures how much a stock's price has changed since January 1st of the current year. This metric is valuable for several reasons:

  • Current Trend Identification: YTD performance reveals which stocks are leading or lagging in the current market cycle, helping identify emerging trends before they become widely recognized.
  • Benchmark Comparison: Compare individual stock performance against market indices like the S&P 500 to assess whether investments are outperforming or underperforming the broader market.
  • Tax Planning: YTD gains and losses are crucial for tax-loss harvesting strategies and estimating potential capital gains tax obligations before year-end.

Factors Driving YTD Performance

Several factors can influence a stock's year-to-date performance:

  • Earnings Reports: Quarterly earnings that beat or miss expectations can significantly impact stock prices throughout the year.
  • Industry Trends: Sector rotation and changing market preferences can drive entire industries higher or lower.
  • Macroeconomic Factors: Interest rates, inflation data, and economic indicators affect stock valuations across the market.
  • Company-Specific News: Product launches, management changes, M&A activity, and regulatory developments can move individual stocks.

Model Your Returns

See exactly how much a YTD top performer would have returned on your investment with our Stock Return Calculator. Planning regular investments? The DCA Calculator shows how dollar-cost averaging into these stocks would have performed.