STOCK TITAN

Opaleye fund adds Alpha Cognition (ACOG) stake with new share purchases

Filing Impact
(Neutral)
Filing Sentiment
(Positive)
Form Type
4

Rhea-AI Filing Summary

Alpha Cognition Inc. reported insider activity by investment manager Opaleye Management Inc., tied to positions held by its affiliated vehicles. On March 27, Opaleye, L.P. executed an open-market purchase of 10,000 common shares at an average price of $5.0792 per share. On March 30, the fund bought an additional 1,850 shares at $4.9873 per share. Following these trades, Opaleye, L.P. held 2,471,850 Alpha Cognition shares indirectly managed by Opaleye Management, and a separately managed account overseen by Opaleye held 90,000 shares. Opaleye Management states it may be deemed a beneficial owner through its roles but disclaims beneficial ownership beyond its pecuniary interest.

Positive

  • None.

Negative

  • None.
Insider Opaleye Management Inc.
Role 10% Owner
Bought 11,850 shs ($60K)
Type Security Shares Price Value
Purchase Common Stock, no par value 1,850 $4.9873 $9K
Purchase Common Stock, no par value 10,000 $5.0792 $51K
holding Common Stock, no par value -- -- --
Holdings After Transaction: Common Stock, no par value — 2,471,850 shares (Indirect, By Opaleye, L.P.)
Footnotes (1)
  1. Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.0674 to $5.0909. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range. Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.
Open-market purchase 10,000 shares at $5.0792 Common Stock bought on March 27, 2026
Additional purchase 1,850 shares at $4.9873 Common Stock bought on March 30, 2026
Net shares bought 11,850 shares Net buy across reported transactions
Fund holdings after trades 2,471,850 shares Opaleye, L.P. Common Stock position following transactions
Managed account holdings 90,000 shares Common Stock held by separately managed account
Net-buy direction 11,850 shares transactionSummary shows net-buy shares
open-market purchase financial
"transaction_action is described as an open-market purchase of common stock"
An open-market purchase is when an investor or a company buys shares on a public stock exchange at the going market price, rather than through a private deal. It matters to investors because these purchases change how many shares are available, can push the stock price up or signal confidence from large buyers, and often affect per-share metrics like earnings—think of it like someone buying lots of apples off a grocery shelf, reducing supply and potentially raising the price.
separately managed account financial
"Securities owned by a separately managed account (the "Managed Account")."
A separately managed account (SMA) is a personalized investment portfolio owned by a single investor and run by a professional manager who buys and sells securities on that investor’s behalf. It matters to investors because an SMA offers tailored asset selection, tax handling, and transparency—like hiring a personal chef who prepares meals to your dietary needs rather than sharing a set menu—so you can align holdings with your goals and see exactly what you own.
beneficially own financial
"Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."
Beneficially own means having the economic rights and risks of a security—such as the right to receive dividends, sell the shares, or profit from price changes—whether or not your name appears on the official share register. Think of it like renting a car: you use it and reap the benefits even if the title lists someone else. Investors care because beneficial ownership determines who truly controls value, must be disclosed under securities rules, and can signal potential influence or trading activity that affects a stock’s price.
pecuniary interest financial
"disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein"
weighted average price financial
"The price reported is a weighted average price for shares purchased in multiple transactions."
Weighted average price is the average price of a security where each trade or component is counted according to its size, so bigger trades pull the average more than smaller ones. Think of it like calculating the average cost of a grocery haul where items you bought more of have greater influence on the final per-item cost. Investors use it to understand the true average price paid or received, judge execution quality, and compare trading performance against market movement.
SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
Opaleye Management Inc.

(Last)(First)(Middle)
ONE BOSTON PLACE, 26TH FLOOR

(Street)
BOSTON MASSACHUSETTS 02108

(City)(State)(Zip)

UNITED STATES

(Country)
2. Issuer Name and Ticker or Trading Symbol
Alpha Cognition Inc. [ ACOG ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
DirectorX10% Owner
Officer (give title below)Other (specify below)
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
03/27/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Common Stock, no par value03/27/2026P10,000A$5.0792(3)2,470,000IBy Opaleye, L.P.(1)(4)
Common Stock, no par value03/30/2026P1,850A$4.98732,471,850IBy Opaleye, L.P.(1)(4)
Common Stock, no par value90,000IBy Managed Account(2)(4)
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Explanation of Responses:
1. Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund.
2. Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.
3. The price reported is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $5.0674 to $5.0909. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range.
4. Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.
Opaleye Management Inc., By: /s/ James Silverman, President03/31/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)

FAQ

What insider transactions did Opaleye Management report in Alpha Cognition (ACOG)?

Opaleye Management reported two open-market purchases by Opaleye, L.P. totaling 11,850 Alpha Cognition common shares. The trades occurred on March 27 and March 30 at average prices near $5.08 and $4.99 per share, respectively.

At what prices did Opaleye, L.P. buy Alpha Cognition (ACOG) shares?

Opaleye, L.P. bought 10,000 Alpha Cognition shares at an average price of $5.0792 on March 27, and 1,850 shares at $4.9873 on March 30. One trade used a weighted average price across multiple executions.

How many Alpha Cognition (ACOG) shares does Opaleye, L.P. hold after these trades?

After the reported open-market purchases, Opaleye, L.P. held 2,471,850 Alpha Cognition common shares. These shares are reported as being owned directly by the fund, with Opaleye Management as its investment manager overseeing the position.

What Alpha Cognition (ACOG) holdings are reported for the separately managed account?

A separately managed account overseen by Opaleye Management is reported as holding 90,000 Alpha Cognition shares. Opaleye is the portfolio manager of this account and may be deemed to beneficially own securities held by it, subject to its pecuniary interest.

Does Opaleye Management claim full beneficial ownership of its Alpha Cognition (ACOG) positions?

Opaleye Management states it may be deemed to beneficially own Alpha Cognition shares held by Opaleye, L.P. and a managed account, but expressly disclaims beneficial ownership of the reported shares except to the extent of its pecuniary interest in those securities.

Were Opaleye’s Alpha Cognition (ACOG) purchases single trades or price ranges?

One Alpha Cognition purchase used a weighted average price between $5.0674 and $5.0909 per share. The filer notes these shares were acquired through multiple transactions and offers to provide detailed price breakdowns upon request.