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ADARx Pharmaceuticals: OrbiMed fund buys 588K shares

Three OrbiMed-affiliated funds made separate common-stock purchases in the IPO at $17 per share.

(Very High)

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Form Type
4

Rhea-AI Filing Summary

ADARx Pharmaceuticals, Inc. (ADRX) had Preferred Stock held by OrbiMed-affiliated funds automatically converted into common shares upon the closing of its initial public offering on September 28, 2026, on a 1-for-1.1717 basis and without further consideration.

In the IPO, OrbiMed Private Investments VII, LP purchased 300,249 shares, OrbiMed Israel Partners II, L.P. purchased 61,516 shares, and OrbiMed Genesis Master Fund, L.P. purchased 588,235 shares, each at $17 per share. The shares were held directly by those funds, while related OrbiMed general partners and advisers reported indirect ownership. The footnotes identify Carl L. Gordon, W. Carter Neild, Geoffrey C. Hsu, David P. Bonita and Erez Chimovits as members of the applicable management committees and state that they disclaim beneficial ownership of the relevant fund shares. No Rule 10b5-1 plan is reported.

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Insider ORBIMED ADVISORS LLC, OrbiMed Capital GP VII LLC, OrbiMed Israel GP II, L.P., OrbiMed Advisors Israel II Ltd, OrbiMed Genesis GP LLC
Role Director, 10% Owner | Director, 10% Owner | Director, 10% Owner | Director, 10% Owner | Director, 10% Owner
Bought 950,000 shs ($16.15M)
Type Security Shares Price Value
Conversion Series A Preferred Stock F1, F3, F6 10,690,530 $0.00 $0.00
Conversion Series B Preferred Stock F1, F3, F6 2,000,962 $0.00 $0.00
Conversion Series B-1 Preferred Stock F1, F3, F6 769,601 $0.00 $0.00
Conversion Series C Preferred Stock F1, F3, F6 564,187 $0.00 $0.00
Conversion Series A Preferred Stock F1, F4, F6 7,127,019 $0.00 $0.00
Conversion Series B Preferred Stock F1, F4, F6 1,333,975 $0.00 $0.00
Conversion Series B-1 Preferred Stock F1, F4, F6 513,067 $0.00 $0.00
Conversion Series C Preferred Stock F1, F4, F6 256,448 $0.00 $0.00
Conversion Common Stock F1, F3, F6 10,690,530 -- --
Conversion Common Stock F1, F3, F6 2,000,962 -- --
Conversion Common Stock F1, F3, F6 769,601 -- --
Conversion Common Stock F1, F3, F6 564,187 -- --
Purchase Common Stock F2, F3, F6 300,249 $17.00 $5.10M
Conversion Common Stock F1, F4, F6 7,127,019 -- --
Conversion Common Stock F1, F4, F6 1,333,975 -- --
Conversion Common Stock F1, F4, F6 513,067 -- --
Conversion Common Stock F1, F4, F6 256,448 -- --
Purchase Common Stock F2, F4, F6 61,516 $17.00 $1.05M
Purchase Common Stock F2, F5, F6 588,235 $17.00 $10.00M
Holdings After Transaction: Series A Preferred Stock — 0 contracts (Indirect, See footnotes); Series B Preferred Stock — 0 contracts (Indirect, See footnotes); Series B-1 Preferred Stock — 0 contracts (Indirect, See footnotes); Series C Preferred Stock — 0 contracts (Indirect, See footnotes); Common Stock — 588,235 shares (Indirect, See footnotes)
Footnotes (6)
  1. F1. Each share of Series A Preferred Stock, Series B Preferred Stock, Series B-1 Preferred Stock, and Series C Preferred Stock (collectively, the "Preferred Stock") automatically converted on a 1-for-1.1717 basis into shares of Common Stock upon the closing of the Issuer's initial public offering without payment of further consideration. Share numbers give effect to such conversion. The Preferred Stock has no expiration date.
  2. F2. Reflects shares of the Issuer's Common Stock purchased in the Issuer's initial public offering.
  3. F3. These securities are held directly by OrbiMed Private Investments VII, LP ("OPI VII"). OrbiMed Capital GP VII LLC ("GP VII") is the general partner of OPI VII. OrbiMed Advisors LLC ("OrbiMed Advisors") is the managing member of GP VII. By virtue of such relationships, GP VII and OrbiMed Advisors may be deemed to have voting power and investment power over the securities held by OPI VII and as a result, may be deemed to have beneficial ownership over such securities. OrbiMed Advisors exercises voting and investment power through a management committee comprised of Carl L. Gordon, W. Carter Neild, and Geoffrey C. Hsu, each of whom disclaims beneficial ownership of the shares held by OPI VII.
  4. F4. These securities are held directly by OrbiMed Israel Partners II, L.P. ("OIP II"). OrbiMed Israel GP II, L.P. ("Israel GP") is the general partner of OIP II. OrbiMed Advisors Israel II Limited ("Advisors Israel") is the general partner of Israel GP. By virtue of such relationships, Israel GP and Advisors Israel may be deemed to have voting power and investment power over the securities held by OIP II and as a result, may be deemed to have beneficial ownership over such securities. Advisors Israel exercises this investment and voting power through a management committee comprised of Carl L. Gordon, David P. Bonita, and Erez Chimovits, each of whom disclaims beneficial ownership of the shares held by OIP II.
  5. F5. These securities are held directly by OrbiMed Genesis Master Fund, L.P. ("OrbiMed Genesis"). OrbiMed Genesis GP LLC ("Genesis GP") is the general partner of OrbiMed Genesis. OrbiMed Advisors is the managing member of Genesis GP. By virtue of such relationships, Genesis GP and OrbiMed Advisors may be deemed to have voting power and investment power over the securities held by OrbiMed Genesis and as a result, may be deemed to have beneficial ownership over such securities. OrbiMed Advisors exercises voting and investment power through a management committee comprised of Carl L. Gordon, W. Carter Neild, and Geoffrey C. Hsu, each of whom disclaims beneficial ownership of the shares held by OrbiMed Genesis.
  6. F6. This report on Form 4 is jointly filed by OrbiMed Advisors, GP VII, Israel GP, Advisors Israel, and Genesis GP. Each of the Reporting Persons disclaims beneficial ownership of the securities reported herein for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), except to the extent of its pecuniary interest therein, if any. The Reporting Persons have designated Carl L. Gordon, a member of OrbiMed Advisors, and Erez Chimovits, an employee of OrbiMed Advisors, to serve on the Issuer's board of directors. This report shall not be deemed an admission that any of such entity or person is a beneficial owner of such securities for purposes of Section 16 of the Exchange Act, or for any other purpose.
IPO shares purchased — OrbiMed Private Investments VII, LP 300,249 shares September 28, 2026, at $17 per share
IPO shares purchased — OrbiMed Israel Partners II, L.P. 61,516 shares September 28, 2026, at $17 per share
IPO shares purchased — OrbiMed Genesis Master Fund, L.P. 588,235 shares September 28, 2026, at $17 per share
Preferred-stock conversion ratio 1-for-1.1717 Into common shares upon closing of the IPO
initial public offering financial
"upon the closing of the Issuer's initial public offering"
An initial public offering (IPO) is when a private company first sells its shares to the public and becomes a stock-listed company. It matters because it allows the company to raise money from a wide range of investors, helping it grow, while giving early shareholders a way to sell some of their ownership.
Preferred Stock financial
"Series A Preferred Stock, Series B Preferred Stock"
Preferred stock is a type of ownership in a company that typically offers investors higher and more consistent dividend payments than common stock. Unlike regular shares, preferred stock usually doesn’t come with voting rights but provides a priority claim on the company’s assets and profits, making it a more stable and predictable investment option. This makes preferred stock attractive to those seeking steady income with lower risk.
pecuniary interest regulatory
"except to the extent of its pecuniary interest therein"

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

How many ADRX shares did OrbiMed-affiliated funds purchase in the IPO?

OrbiMed Private Investments VII, LP bought 300,249 shares, OrbiMed Israel Partners II, L.P. bought 61,516, and OrbiMed Genesis Master Fund, L.P. bought 588,235, each at $17 per share on September 28, 2026. No Rule 10b5-1 plan is reported.

What was ADRX's preferred-stock conversion ratio at the IPO?

Series A, Series B, Series B-1 and Series C Preferred Stock automatically converted into Common Stock on a 1-for-1.1717 basis upon closing of the IPO, without further consideration.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Learn about SEC filing dates
SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
ORBIMED ADVISORS LLC

(Last)(First)(Middle)
601 LEXINGTON AVENUE
54TH FLOOR

(Street)
NEW YORK NEW YORK 10022

(City)(State)(Zip)

UNITED STATES

(Country)
2. Issuer Name and Ticker or Trading Symbol
ADARx Pharmaceuticals, Inc. [ ADRX ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
XDirectorX10% Owner
Officer (give title below)Other (specify below)
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
09/28/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
Form filed by One Reporting Person
XForm filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Common Stock09/28/2026C10,690,530A(1)10,690,530ISee footnotes(3)(6)
Common Stock09/28/2026C2,000,962A(1)12,691,492ISee footnotes(3)(6)
Common Stock09/28/2026C769,601A(1)13,461,093ISee footnotes(3)(6)
Common Stock09/28/2026C564,187A(1)14,025,280ISee footnotes(3)(6)
Common Stock09/28/2026P300,249(2)A$1714,325,529ISee footnotes(3)(6)
Common Stock09/28/2026C7,127,019A(1)7,127,019ISee footnotes(4)(6)
Common Stock09/28/2026C1,333,975A(1)8,460,994ISee footnotes(4)(6)
Common Stock09/28/2026C513,067A(1)8,974,061ISee footnotes(4)(6)
Common Stock09/28/2026C256,448A(1)9,230,509ISee footnotes(4)(6)
Common Stock09/28/2026P61,516(2)A$179,292,025ISee footnotes(4)(6)
Common Stock09/28/2026P588,235(2)A$17588,235ISee footnotes(5)(6)
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Series A Preferred Stock(1)09/28/2026C10,690,530 (1) (1)Common Stock10,690,530$00ISee footnotes(3)(6)
Series B Preferred Stock(1)09/28/2026C2,000,962 (1) (1)Common Stock2,000,962$00ISee footnotes(3)(6)
Series B-1 Preferred Stock(1)09/28/2026C769,601 (1) (1)Common Stock769,601$00ISee footnotes(3)(6)
Series C Preferred Stock(1)09/28/2026C564,187 (1) (1)Common Stock564,187$00ISee footnotes(3)(6)
Series A Preferred Stock(1)09/28/2026C7,127,019 (1) (1)Common Stock7,127,019$00ISee footnotes(4)(6)
Series B Preferred Stock(1)09/28/2026C1,333,975 (1) (1)Common Stock1,333,975$00ISee footnotes(4)(6)
Series B-1 Preferred Stock(1)09/28/2026C513,067 (1) (1)Common Stock513,067$00ISee footnotes(4)(6)
Series C Preferred Stock(1)09/28/2026C256,448 (1) (1)Common Stock256,448$00ISee footnotes(4)(6)
1. Name and Address of Reporting Person*
ORBIMED ADVISORS LLC

(Last)(First)(Middle)
601 LEXINGTON AVENUE
54TH FLOOR

(Street)
NEW YORK NEW YORK 10022

(City)(State)(Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer
XDirectorX10% Owner
Officer (give title below)Other (specify below)
1. Name and Address of Reporting Person*
OrbiMed Capital GP VII LLC

(Last)(First)(Middle)
601 LEXINGTON AVENUE, 54TH FLOOR

(Street)
NEW YORK NEW YORK 10022

(City)(State)(Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer
XDirectorX10% Owner
Officer (give title below)Other (specify below)
1. Name and Address of Reporting Person*
OrbiMed Israel GP II, L.P.

(Last)(First)(Middle)
601 LEXINGTON AVENUE
54TH FLOOR

(Street)
NEW YORK NEW YORK 10022

(City)(State)(Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer
XDirectorX10% Owner
Officer (give title below)Other (specify below)
1. Name and Address of Reporting Person*
OrbiMed Advisors Israel II Ltd

(Last)(First)(Middle)
601 LEXINGTON AVENUE
54TH FLOOR

(Street)
NEW YORK NEW YORK 10022

(City)(State)(Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer
XDirectorX10% Owner
Officer (give title below)Other (specify below)
1. Name and Address of Reporting Person*
OrbiMed Genesis GP LLC

(Last)(First)(Middle)
601 LEXINGTON AVENUE, 54TH FLOOR

(Street)
NEW YORK NEW YORK 10022

(City)(State)(Zip)

UNITED STATES

(Country)

Relationship of Reporting Person(s) to Issuer
XDirectorX10% Owner
Officer (give title below)Other (specify below)
Explanation of Responses:
1. Each share of Series A Preferred Stock, Series B Preferred Stock, Series B-1 Preferred Stock, and Series C Preferred Stock (collectively, the "Preferred Stock") automatically converted on a 1-for-1.1717 basis into shares of Common Stock upon the closing of the Issuer's initial public offering without payment of further consideration. Share numbers give effect to such conversion. The Preferred Stock has no expiration date.
2. Reflects shares of the Issuer's Common Stock purchased in the Issuer's initial public offering.
3. These securities are held directly by OrbiMed Private Investments VII, LP ("OPI VII"). OrbiMed Capital GP VII LLC ("GP VII") is the general partner of OPI VII. OrbiMed Advisors LLC ("OrbiMed Advisors") is the managing member of GP VII. By virtue of such relationships, GP VII and OrbiMed Advisors may be deemed to have voting power and investment power over the securities held by OPI VII and as a result, may be deemed to have beneficial ownership over such securities. OrbiMed Advisors exercises voting and investment power through a management committee comprised of Carl L. Gordon, W. Carter Neild, and Geoffrey C. Hsu, each of whom disclaims beneficial ownership of the shares held by OPI VII.
4. These securities are held directly by OrbiMed Israel Partners II, L.P. ("OIP II"). OrbiMed Israel GP II, L.P. ("Israel GP") is the general partner of OIP II. OrbiMed Advisors Israel II Limited ("Advisors Israel") is the general partner of Israel GP. By virtue of such relationships, Israel GP and Advisors Israel may be deemed to have voting power and investment power over the securities held by OIP II and as a result, may be deemed to have beneficial ownership over such securities. Advisors Israel exercises this investment and voting power through a management committee comprised of Carl L. Gordon, David P. Bonita, and Erez Chimovits, each of whom disclaims beneficial ownership of the shares held by OIP II.
5. These securities are held directly by OrbiMed Genesis Master Fund, L.P. ("OrbiMed Genesis"). OrbiMed Genesis GP LLC ("Genesis GP") is the general partner of OrbiMed Genesis. OrbiMed Advisors is the managing member of Genesis GP. By virtue of such relationships, Genesis GP and OrbiMed Advisors may be deemed to have voting power and investment power over the securities held by OrbiMed Genesis and as a result, may be deemed to have beneficial ownership over such securities. OrbiMed Advisors exercises voting and investment power through a management committee comprised of Carl L. Gordon, W. Carter Neild, and Geoffrey C. Hsu, each of whom disclaims beneficial ownership of the shares held by OrbiMed Genesis.
6. This report on Form 4 is jointly filed by OrbiMed Advisors, GP VII, Israel GP, Advisors Israel, and Genesis GP. Each of the Reporting Persons disclaims beneficial ownership of the securities reported herein for purposes of Rule 16a-1(a) under the Securities Exchange Act of 1934, as amended (the "Exchange Act"), except to the extent of its pecuniary interest therein, if any. The Reporting Persons have designated Carl L. Gordon, a member of OrbiMed Advisors, and Erez Chimovits, an employee of OrbiMed Advisors, to serve on the Issuer's board of directors. This report shall not be deemed an admission that any of such entity or person is a beneficial owner of such securities for purposes of Section 16 of the Exchange Act, or for any other purpose.
/s/ Carl L. Gordon, Member of OrbiMed Advisors LLC09/30/2026
/s/ Carl L. Gordon, Member of OrbiMed Capital GP VII LLC09/30/2026
/s/ Carl L. Gordon, Director of OrbiMed Israel GP II, L.P09/30/2026
/s/ Carl L. Gordon, Director of OrbiMed Advisors Israel II Limited09/30/2026
/s/ Carl L. Gordon, Member of OrbiMed Genesis GP LLC09/30/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)

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