[Form 4] Alector, Inc. Insider Trading Activity

Rhea-AI Filing Summary

Insider transaction: On 06/20/2025, Alector, Inc. (ALEC) director Kristine Yaffe sold 1,000 shares of common stock at a price of $1.44 per share, according to a Form 4 filed with the SEC.

Following the sale, Yaffe’s direct beneficial ownership stands at 95,409 shares. No derivative security activity was reported, and the filing was signed on 06/23/2025 by attorney-in-fact Danielle Pasqualone.

Positive

• Director continues to hold 95,409 shares, maintaining a substantive ownership stake that aligns interests with other shareholders.

Negative

• Sale of 1,000 shares at $1.44 slightly reduces insider ownership and could be viewed as a modest bearish signal by some investors.

Insights

Securities Analyst

TL;DR: Minor director sale—neutral impact, negligible ownership change.

The transaction represents roughly 1% of the director’s prior holdings (1,000 of ~96,409 shares) and a cash value of only $1,440. Scale and single-day nature suggest routine portfolio management rather than a material signal. Insider still retains a meaningful stake, maintaining alignment with shareholders. No additional transactions or derivative activity noted, keeping the disclosure straightforward. Given the modest size, market impact is expected to be minimal.

Corporate Governance Expert

TL;DR: Routine Form 4; governance compliance intact; low investor significance.

The filing meets Section 16 reporting obligations and indicates timely disclosure within two business days. There is no 10b5-1 plan box checked, implying a discretionary trade. Absence of footnotes or complex structures underscores transparency. From a governance standpoint, a small sale of this magnitude does not raise red flags regarding board commitment or potential conflicts. Overall, the event is categorized as ordinary and non-impactful.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

X

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Yaffe Kristine

(Last) (First) (Middle)

C/O ALECTOR, INC.

131 OYSTER POINT BLVD., SUITE 600

(Street)

SOUTH SAN FRANCISCO CA 94080

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
Alector, Inc. [ ALEC ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
	Officer (give title below)		Other (specify below)

3. Date of Earliest Transaction (Month/Day/Year)
06/20/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	06/20/2025		S		1,000	D	$1.44	95,409	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

	/s/ Danielle Pasqualone, by power of attorney	06/23/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

How many Alector (ALEC) shares did director Kristine Yaffe sell?

She sold 1,000 shares of common stock.

At what price were the Alector shares sold?

The shares were sold at $1.44 per share.

What is Kristine Yaffe’s remaining share ownership after the sale?

She now beneficially owns 95,409 shares directly.

When was the transaction reported to the SEC?

The Form 4 was signed on 06/23/2025 and reports a transaction date of 06/20/2025.

Were any derivative securities involved in this Form 4 filing?

No derivative security transactions were reported in this filing.