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Alector Financials

ALEC
Source SEC Filings (10-K/10-Q) Data as of Mar 31, 2026 Currency USD FYE December

This page shows Alector (ALEC) financial statements, including the income statement, balance sheet, cash flow statement, and key financial ratios. View 9 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Rhea AI ALEC FY2025

Alector’s current model is balance-sheet-funded drug development, with research spending far above revenue and equity steadily thinning.

FY2025 operating cash burn of -$184.0M against just $21.0M of revenue shows the business is still financed primarily by capital already on the balance sheet, not by its current income stream. With year-end cash at $65.8M, that burn was bridged mainly by liquidating investments, visible in a $196.6M investing inflow rather than in self-funding operations.

Revenue compression mattered more than cost cuts: revenue fell to $21.0M from $100.6M in FY2024, pointing to an uneven revenue base rather than stable commercial scale. R&D spending was reduced, but the operating loss still deepened, which suggests a sizable research platform has to be funded even when revenue is thin.

The current ratio of 3.8x looks comfortable, but year-end cash was only $65.8M, so short-term flexibility depends on other current assets being monetized rather than on cash alone. Equity erosion from $300.7M in FY2021 to $30.6M in FY2025 shows repeated losses have consumed most of the original capital cushion, leaving a much thinner balance sheet even without large debt.

[ NOT FINANCIAL ADVICE ]

Financial Health Signals

Cash Runway Dilution R&D Intensity Revenue Progress Burn Trend Balance Sheet 41 / 100
Financial Health Score 41/100
Scored as: Emerging companies peer group

Scored against emerging companies for FY2025. Each of the six dimensions is a percentile rank within that peer group; the overall is their average, with missing dimensions counted as zero out of six. A high score means strong standing among peers, not absolute cross-industry strength. How this score is calculated →

Health score ≠ stock price. This rates the quality of Alector's business: profitability, growth, balance sheet strength. It doesn't tell you whether the stock is a good buy at today's price. Not financial advice. Use it alongside valuation analysis and your own research.

Cash Runway
22
Dilution
43
R&D Intensity
91
Revenue Progress
5
Burn Trend
43
Balance Sheet
42
Altman Z-Score Distress
-5.10

Alector scores -5.10, below the 1.81 distress threshold. The score is driven primarily by a large market capitalization ($181.5M) relative to total liabilities ($262.6M). This indicates elevated financial distress risk and warrants close attention to liquidity and debt levels.

Distress-screening estimate for non-financial companies. Not computed for banks or insurers, where the Altman model does not apply.

Piotroski F-Score Partial
1/8

Alector passes 1 of 8 computable financial strength tests (1 of the nine could not be computed from available data). No profitability signals pass, 1 of 3 leverage/liquidity signals pass, neither operating efficiency signal passes.

Earnings Quality Low Quality
1.29x

For every $1 of reported earnings, Alector generates $1.29 in operating cash flow (-$184.0M OCF vs -$143.0M net income). This low ratio suggests earnings are primarily driven by accounting accruals rather than cash generation, which may not be sustainable.

Key Financial Metrics

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Earnings & Revenue

Revenue
$21.0M
YoY-79.1%
5Y CAGR-0.1%

Alector generated $21.0M in revenue in fiscal year 2025. This represents a decrease of 79.1% from the prior year.

EBITDA
-$150.3M
YoY-7.7%

Alector's EBITDA was -$150.3M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents a decrease of 7.7% from the prior year.

Net Income
-$143.0M
YoY-20.2%

Alector reported -$143.0M in net income in fiscal year 2025. This represents a decrease of 20.2% from the prior year.

EPS (Diluted)
$-1.39
YoY-13.0%

Alector earned $-1.39 per diluted share (EPS) in fiscal year 2025. This represents a decrease of 13.0% from the prior year.

Cash & Balance Sheet

Free Cash Flow
-$184.1M
YoY+20.4%

Alector generated -$184.1M in free cash flow in fiscal year 2025, representing cash available after capex. This represents an increase of 20.4% from the prior year.

Cash & Debt
$65.8M
YoY+99.3%
5Y CAGR+5.7%

Alector held $65.8M in cash against $9.3M in long-term debt as of fiscal year 2025.

Dividends Per Share
N/A
Shares Outstanding
110M
YoY+11.4%
5Y CAGR+6.8%

Alector had 110M shares outstanding in fiscal year 2025. This represents an increase of 11.4% from the prior year.

Margins & Returns

Gross Margin
N/A
Operating Margin
-741.3%
YoY-597.1pp
5Y CAGR+183.8pp

Alector's operating margin was -741.3% in fiscal year 2025, reflecting core business profitability. This is down 597.1 percentage points from the prior year.

Net Margin
-679.5%
YoY-561.2pp
5Y CAGR+222.1pp

Alector's net profit margin was -679.5% in fiscal year 2025, showing the share of revenue converted to profit. This is down 561.2 percentage points from the prior year.

Return on Equity
-466.6%
YoY-372.7pp
5Y CAGR-395.5pp

Alector's ROE was -466.6% in fiscal year 2025, measuring profit generated per dollar of shareholder equity. This is down 372.7 percentage points from the prior year.

Capital Allocation

R&D Spending
$123.1M
YoY-33.8%
5Y CAGR-4.7%

Alector invested $123.1M in research and development in fiscal year 2025. This represents a decrease of 33.8% from the prior year.

Share Buybacks
N/A
Capital Expenditures
$41K
YoY-96.7%
5Y CAGR-61.8%

Alector invested $41K in capex in fiscal year 2025, funding long-term assets and infrastructure. This represents a decrease of 96.7% from the prior year.

ALEC Income Statement

Metric Q1'26 Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24
Revenue $1.0M-83.2% $6.2M+90.5% $3.3M-58.6% $7.9M+112.8% $3.7M-93.2% $54.2M+253.5% $15.3M+1.7% $15.1M
Cost of Revenue N/A N/A N/A N/A N/A N/A N/A N/A
Gross Profit N/A N/A N/A N/A N/A N/A N/A N/A
R&D Expenses $17.9M-45.0% $32.5M+10.6% $29.4M+6.3% $27.6M-17.9% $33.6M-27.6% $46.5M-3.2% $48.0M+3.6% $46.3M
SG&A Expenses $8.1M-39.2% $13.3M+15.8% $11.5M-20.0% $14.4M-2.2% $14.7M-2.0% $15.0M-4.8% $15.8M+9.8% $14.4M
Operating Income -$24.9M+37.0% -$39.6M-5.2% -$37.6M-10.2% -$34.1M+23.6% -$44.7M-516.6% -$7.2M+85.0% -$48.4M-6.2% -$45.6M
Interest Expense N/A N/A N/A N/A N/A N/A N/A N/A
Income Tax $0-100.0% $168K $0 $0 $0-100.0% $48K $0-100.0% $73K
Net Income -$22.9M+38.6% -$37.3M-7.7% -$34.7M-13.6% -$30.5M+24.6% -$40.5M-1898.6% -$2.0M+95.2% -$42.2M-9.2% -$38.7M
EPS (Diluted) $-0.21 N/A $-0.34-13.3% $-0.30+26.8% $-0.41 N/A $-0.43-7.5% $-0.40

ALEC Balance Sheet

Metric Q1'26 Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24
Total Assets $239.9M-18.2% $293.2M-12.5% $335.3M-5.9% $356.4M-12.7% $408.3M-12.8% $468.3M-9.2% $516.0M-9.6% $570.7M
Current Assets $215.1M-19.3% $266.5M-11.3% $300.4M-5.9% $319.2M-12.9% $366.6M-13.7% $424.8M-9.5% $469.4M-9.7% $519.7M
Cash & Equivalents $77.0M+17.0% $65.8M-14.0% $76.5M+70.9% $44.8M+17.9% $38.0M+15.0% $33.0M-11.1% $37.2M-21.8% $47.5M
Inventory N/A N/A N/A N/A N/A N/A N/A N/A
Accounts Receivable N/A N/A N/A N/A N/A N/A N/A N/A
Goodwill N/A N/A N/A N/A N/A N/A N/A N/A
Total Liabilities $229.5M-12.6% $262.6M-5.4% $277.6M-2.7% $285.2M-9.1% $313.7M-8.1% $341.5M-14.0% $397.1M-5.5% $420.2M
Current Liabilities $41.0M-41.1% $69.5M-13.1% $80.0M-5.2% $84.4M-23.2% $109.8M-12.2% $125.1M-12.3% $142.5M-3.5% $147.7M
Long-Term Debt $8.3M-11.1% $9.3M-3.0% $9.6M+0.8% $9.5M+0.8% $9.5M+0.8% $9.4M N/A N/A
Total Equity $10.4M-66.1% $30.6M-46.9% $57.7M-18.9% $71.2M-24.8% $94.6M-25.4% $126.8M+6.6% $118.9M-21.0% $150.6M
Retained Earnings -$995.0M-2.4% -$972.1M-4.0% -$934.8M-3.9% -$900.1M-3.5% -$869.6M-4.9% -$829.1M-0.3% -$827.1M-5.4% -$784.8M

ALEC Cash Flow Statement

Metric Q1'26 Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24
Operating Cash Flow -$49.8M-19.5% -$41.7M-28.2% -$32.5M+33.7% -$49.0M+19.3% -$60.8M-10.5% -$55.0M-8.5% -$50.7M+19.2% -$62.8M
Capital Expenditures $118K $0-100.0% $11K+10.0% $10K-50.0% $20K-88.4% $173K-18.4% $212K-37.1% $337K
Free Cash Flow -$49.9M-19.8% -$41.7M-28.2% -$32.5M+33.7% -$49.1M+19.3% -$60.8M-10.1% -$55.2M-8.4% -$50.9M+19.3% -$63.1M
Investing Cash Flow $60.9M+138.1% $25.6M-48.3% $49.5M-11.1% $55.7M-15.2% $65.7M+58.8% $41.4M+2.6% $40.3M+8.6% $37.1M
Financing Cash Flow $25K-99.5% $5.4M-63.3% $14.7M+11950.0% $122K $0-100.0% $9.8M $0-100.0% $644K
Dividends Paid N/A N/A N/A N/A N/A N/A N/A N/A
Share Buybacks N/A N/A N/A N/A N/A N/A N/A N/A

ALEC Financial Ratios

Metric Q1'26 Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24
Gross Margin N/A N/A N/A N/A N/A N/A N/A N/A
Operating Margin -2382.3%-1745.3pp -637.0%+516.6pp -1153.6%-720.1pp -433.5%+774.4pp -1208.0%-1194.6pp -13.4%+302.3pp -315.7%-13.3pp -302.4%
Net Margin -2192.2%-1591.0pp -601.2%+462.2pp -1063.4%-675.7pp -387.7%+706.2pp -1093.8%-1090.1pp -3.7%+271.5pp -275.2%-18.8pp -256.4%
Return on Equity -220.9%-99.0pp -121.8%-61.8pp -60.1%-17.2pp -42.9%-0.1pp -42.8%-41.2pp -1.6%+33.9pp -35.5%-9.8pp -25.7%
Return on Assets -9.6%+3.2pp -12.7%-2.4pp -10.3%-1.8pp -8.6%+1.3pp -9.9%-9.5pp -0.4%+7.8pp -8.2%-1.4pp -6.8%
Current Ratio 5.25+1.4 3.83+0.1 3.76-0.0 3.78+0.4 3.34-0.1 3.40+0.1 3.29-0.2 3.52
Debt-to-Equity 0.80+0.5 0.30+0.1 0.17+0.0 0.13+0.0 0.10+0.0 0.07-3.3 3.34+0.5 2.79
FCF Margin -4773.5%-4102.3pp -671.2%+326.4pp -997.6%-374.6pp -623.0%+1020.3pp -1643.3%-1541.5pp -101.8%+230.3pp -332.1%+86.5pp -418.6%

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Frequently Asked Questions

Alector (ALEC) reported $21.0M in total revenue for fiscal year 2025. This represents a -79.1% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

Alector (ALEC) revenue declined by 79.1% year-over-year, from $100.6M to $21.0M in fiscal year 2025.

No, Alector (ALEC) reported a net income of -$143.0M in fiscal year 2025, with a net profit margin of -679.5%.

Alector (ALEC) reported diluted earnings per share of $-1.39 for fiscal year 2025. This represents a -13.0% change compared to the previous fiscal year. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Alector (ALEC) had EBITDA of -$150.3M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

As of fiscal year 2025, Alector (ALEC) had $65.8M in cash and equivalents against $9.3M in long-term debt.

Alector (ALEC) had an operating margin of -741.3% in fiscal year 2025, reflecting the profitability of core business operations before interest and taxes.

Alector (ALEC) had a net profit margin of -679.5% in fiscal year 2025, representing the share of revenue converted into profit after all expenses.

Alector (ALEC) has a return on equity of -466.6% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

Alector (ALEC) generated -$184.1M in free cash flow during fiscal year 2025. This represents a 20.4% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

Alector (ALEC) generated -$184.0M in operating cash flow during fiscal year 2025, representing cash generated from core business activities.

Alector (ALEC) had $293.2M in total assets as of fiscal year 2025, including both current and long-term assets.

Alector (ALEC) invested $41K in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

Alector (ALEC) invested $123.1M in research and development during fiscal year 2025.

Alector (ALEC) had 110M shares outstanding as of fiscal year 2025.

Alector (ALEC) had a current ratio of 3.83 as of fiscal year 2025, which is generally considered healthy.

Alector (ALEC) had a debt-to-equity ratio of 0.30 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

Alector (ALEC) had a return on assets of -48.8% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

Based on fiscal year 2025 data, Alector (ALEC) had $65.8M in cash against an annual operating cash burn of $184.0M. This gives an estimated cash runway of approximately 4 months at the current burn rate. Cash runway measures how long a company can continue operating before running out of cash, assuming no additional funding.

Alector (ALEC) has an Altman Z-Score of -5.10, placing it in the Distress Zone (elevated bankruptcy risk). The Z-Score combines five financial ratios (working capital, retained earnings, EBIT, market capitalization, and revenue relative to total assets) to predict the likelihood of bankruptcy. Scores above 2.99 indicate financial safety while scores below 1.81 suggest financial distress. Learn more in our complete guide to financial health indicators.

Alector (ALEC) has a Piotroski F-Score of 1 out of 8 computable signals; 1 of the nine could not be computed from available data, so the full-scale strength rating is not shown. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Alector (ALEC) has an earnings quality ratio of 1.29x, considered low quality (accrual-driven). This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

Alector (ALEC) scores 41 out of 100 on our Financial Health Score, indicating moderate standing within its emerging companies peer group. The score is a 0-100 composite of six dimensions (Cash Runway, Dilution, R&D Intensity, Revenue Progress, Burn Trend, Balance Sheet), each ranked as a percentile relative to companies in the same scoring family (banks against banks, REITs against REITs, and so on) rather than across all industries. It rates the quality of the business, not whether the stock is fairly priced, and is not financial advice. Learn more in our complete guide to financial health indicators.

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