[Form 4] Alector, Inc. Insider Trading Activity

Rhea-AI Filing Summary

Paula Hammond, a director of Alector, Inc. (ALEC), reported a planned sale of common stock executed on 08/26/2025 under a Rule 10b5-1 trading plan adopted on May 27, 2025. The filing shows 14,000 shares were sold at a weighted average price of $2.357, with individual trade prices ranging from $2.31 to $2.385. After the reported sales, Hammond beneficially owned 74,909 shares directly. The Form 4 was submitted by one reporting person and signed by Grace Wong-Sarad by power of attorney on 08/27/2025. All details in this summary are taken directly from the Form 4 provided.

Positive

• Sale executed under a Rule 10b5-1 trading plan, indicating prearranged, compliant insider trading
• Transparent pricing disclosure: weighted average price ($2.357) and price range ($2.31–$2.385) provided

Negative

• Director holdings reduced by 14,000 shares, leaving 74,909 shares beneficially owned following the sale

Insights

Financial Analyst

TL;DR: Routine insider sale under a 10b5-1 plan; modest reduction in director holdings, no other material disclosures.

The reported transaction is a non-derivative sale of 14,000 common shares by Director Paula Hammond executed on 08/26/2025 pursuant to a Rule 10b5-1 plan adopted 05/27/2025. The weighted average sale price was $2.357 with trades between $2.31 and $2.385. Post-sale direct beneficial ownership is 74,909 shares. From a financial perspective, this is a compliant, prearranged disposition that typically signals liquidity needs or portfolio rebalancing rather than new company-sensitive information. No earnings, debt changes, or material corporate actions are disclosed in this Form 4.

Corporate Governance Expert

TL;DR: Disclosure follows governance best practices: use of 10b5-1 plan and clear price/range reporting.

The filing clearly indicates the sale was effected under a Rule 10b5-1 trading plan, which provides an affirmative defense against insider trading claims when properly adopted. The Form 4 reports the weighted average price and the price range for the multiple transactions, and it shows the reporting mechanism and signature by power of attorney. These elements reflect standard, transparent insider reporting. There are no indications in this filing of unusual timing or related-party transactions.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

X

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Hammond Paula

(Last) (First) (Middle)

C/O ALECTOR, INC.

131 OYSTER POINT BLVD. SUITE 600

(Street)

SOUTH SAN FRANCISCO CA 94080

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
Alector, Inc. [ ALEC ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
	Officer (give title below)		Other (specify below)

3. Date of Earliest Transaction (Month/Day/Year)
08/26/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	08/26/2025		S(1)		14,000	D	$2.357(2)	74,909	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on May 27, 2025.

2. The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $2.31 to $2.385. Full information regarding the number of shares sold at each separate price can be furnished to the SEC staff, the issuer, or any security holder of the issuer upon request.

	/s/ Grace Wong-Sarad, by power of attorney	08/27/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What did Paula Hammond (ALEC) report on Form 4?

The Form 4 reports that Director Paula Hammond sold 14,000 shares of Alector common stock on 08/26/2025 under a Rule 10b5-1 plan.

At what price were the ALEC shares sold in the Form 4 filing?

The filing reports a weighted average price of $2.357; individual trades ranged from $2.31 to $2.385.

How many ALEC shares does Paula Hammond own after the reported sale?

After the reported transactions, Paula Hammond beneficially owned 74,909 shares directly.

Was the sale reported under a trading plan for ALEC insider?

Yes. The Form 4 indicates the transactions were effected pursuant to a Rule 10b5-1 trading plan adopted on May 27, 2025.

Who signed the Form 4 for the ALEC filing?

The Form 4 is signed by Grace Wong-Sarad by power of attorney on behalf of the reporting person, dated 08/27/2025.