Alector to Host Virtual Research and Development Event Highlighting PGRN Franchise and Brain Carrier Programs

Rhea-AI Summary

Alector (Nasdaq: ALEC) announced a virtual R&D event scheduled for September 22, 2025, focusing on their progranulin (PGRN) franchise and Alector Brain Carrier (ABC) programs. The presentation will highlight two key clinical programs: latozinemab, in Phase 3 trials for frontotemporal dementia, and AL101, in Phase 2 trials for early Alzheimer's disease.

The event will also showcase preclinical data from their ABC-enabled programs, including a brain-penetrant anti-amyloid beta antibody for Alzheimer's and a GCase-enzyme replacement therapy for Parkinson's disease. Additionally, updates on ABC-enabled siRNA programs will be presented, demonstrating the platform's versatility in treating neurodegenerative diseases.

--Agenda to feature latozinemab and AL101, along with progress in Alector Brain Carrier–enabled programs, including new lead candidates--

SOUTH SAN FRANCISCO, Calif., Sept. 16, 2025 (GLOBE NEWSWIRE) -- Alector, Inc. (Nasdaq: ALEC), a late-stage clinical biotechnology company focused on developing therapies to counteract the devastating progression of neurodegeneration, today announced management will host a virtual event to discuss the company’s progranulin (PGRN) franchise and Alector Brain Carrier (ABC)–enabled programs. The event will include a review of latozinemab, currently being evaluated in a pivotal Phase 3 trial for frontotemporal dementia due to a GRN gene mutation, and AL101, which is in a Phase 2 trial for early Alzheimer’s disease (AD). In addition, the company will present preclinical data on lead candidates for its ABC–enabled programs, including its brain-penetrant anti-amyloid beta antibody program for AD, and its brain-penetrant engineered GCase-enzyme replacement therapy for Parkinson’s disease. The event will also highlight progress in Alector’s ABC-enabled siRNA programs, which expand the platform’s reach across different cargos for the treatment of neurodegenerative diseases.

Details of the webinar are as follows:

Alector R&D Briefing: A Review of Our PGRN Franchise and Brain Carrier Programs
Monday, September 22, 2025, from 12:00 to 1:30 pm EDT

A live question and answer session will follow the formal presentation. To access the live webcast of this event, please register here, or visit “Events and Presentations” in the “Investors” section of the Alector website at https://investors.alector.com. An archived replay will be available for approximately 90 days following the presentation.

About Alector
Alector is a late-stage clinical biotechnology company focused on developing therapies to counteract the devastating progression of neurodegenerative diseases. Leveraging the principles of genetics, immunology, and neuroscience, the company is advancing a portfolio of genetically validated programs that aim to remove toxic proteins, replace deficient proteins, and restore immune and nerve cell function. Supported by biomarkers, Alector’s product candidates seek to treat a range of indications, such as frontotemporal dementia, Alzheimer’s disease, and Parkinson's disease. The company is also developing Alector Brain Carrier (ABC), a proprietary blood-brain barrier platform, which is being selectively applied to its next-generation product candidates and research pipeline. ABC aims to enhance the delivery of therapeutics, achieve deeper brain penetration and efficacy at lower doses, and ultimately improve patient outcomes while reducing costs. Alector is headquartered in South San Francisco, California. For more information, please visit www.alector.com.

Alector Contacts:
Alector
Katie Hogan
202-549-0557
katie.hogan@alector.com

Argot Partners (media)
David Rosen
646-461-6387
alector@argotpartners.com

Argot Partners (investors)
Laura Perry
212-600-1902
alector@argotpartners.com

FAQ

When is Alector's (ALEC) R&D event and how can investors access it?

The virtual R&D event is scheduled for September 22, 2025, from 12:00 to 1:30 pm EDT. Investors can access the webcast by registering through Alector's investor relations website.

What clinical programs will Alector (ALEC) discuss during the R&D event?

Alector will discuss latozinemab (Phase 3 trial for frontotemporal dementia with GRN mutation) and AL101 (Phase 2 trial for early Alzheimer's disease).

What are the key preclinical programs in Alector's (ALEC) Brain Carrier platform?

The key preclinical programs include a brain-penetrant anti-amyloid beta antibody for Alzheimer's disease and a brain-penetrant engineered GCase-enzyme replacement therapy for Parkinson's disease.

How long will Alector's (ALEC) R&D presentation be available for replay?

An archived replay of the presentation will be available for approximately 90 days following the event.