[Form 4] Alnylam Pharmaceuticals, Inc. Insider Trading Activity

Rhea-AI Filing Summary

BJ’s Wholesale Club Holdings, Inc. (BJ) — Form 4 insider transaction

President & CEO Robert W. Eddy filed a Form 4 for trades executed on 1 July 2025. Mr. Eddy, who is also a director, sold a total of 17,900 BJ common shares in three market transactions:

• 7,308 shares at a weighted-average $106.73
• 9,894 shares at a weighted-average $107.27
• 698 shares at a weighted-average $108.03

The weighted-average sale price range spanned $105.98–$108.07. After the sales, the CEO retains 368,333 shares held directly and 2,000 shares held indirectly through dependent children, leaving him with roughly 370k shares in total. The disposition represents ≈4.6 % of his prior direct ownership.

No derivative securities were reported. The filing does not reference a Rule 10b5-1 trading plan, so the sales appear discretionary. Investors often watch C-suite sales for sentiment signals; however, the executive continues to hold a sizeable equity stake, which may temper negative interpretations.

Positive

• CEO retains a substantial direct holding of 368,333 shares, maintaining strong equity alignment with shareholders.
• Sale represents less than 5 % of prior holdings, suggesting routine diversification rather than a major reduction.

Negative

• President & CEO sold 17,900 shares (~$1.9 M), which can be perceived as a bearish sentiment signal.
• No disclosure of a Rule 10b5-1 trading plan, indicating the sales were discretionary and potentially timing-related.

Insights

Equity Analyst

TL;DR – Routine but sizeable CEO sale (~$1.9 M); sentiment mildly negative yet ownership remains strong.

The 17.9 k-share sale equates to about 4–5 % of Mr. Eddy’s position, generating roughly $1.9 million in proceeds. The absence of accompanying derivatives exercise or 10b5-1 plan suggests opportunistic profit-taking rather than pre-scheduled diversification. While single-day CEO disposals often draw scrutiny, his remaining 368 k shares (≈$39 M at filing price) demonstrate continued alignment with shareholders. Given the magnitude relative to float and average daily volume, the transaction is unlikely to affect market liquidity. Overall impact is neutral to slightly negative; investors should monitor for additional insider selling trends.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Fitzgerald Kevin Joseph

(Last) (First) (Middle)

675 WEST KENDALL STREET

HENRI A. TERMEER SQUARE

(Street)

CAMBRIDGE MA 02142

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
ALNYLAM PHARMACEUTICALS, INC. [ ALNY ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	CSO & EVP, Head of Research

3. Date of Earliest Transaction (Month/Day/Year)
07/01/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	07/01/2025		A		7,763(1)	A	$0.0	21,264	D
Common Stock								537	I	by Managed Account(2)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. These shares are represented by restricted stock units (RSUs) granted under the Amended and Restated 2018 Stock Incentive Plan. Each RSU represents a contingent right to receive one share of common stock. The RSUs will vest over a three-year period, with one third vesting on each of the first, second and third anniversaries of the grant date, subject to the Reporting Persons continuous service with the Issuer as of each such vesting date.

2. Reflects shares of ALNY common stock acquired by the Reporting Person under the issuer 401(k) plan as a result of the issuer 401(k) matching contribution program.

	By: Brett Budzinski, Attorney-in-Fact For: Kevin Fitzgerald	07/02/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

How many BJ shares did the CEO sell on 1 July 2025?

Robert W. Eddy sold 17,900 common shares of BJ’s Wholesale Club Holdings.

What prices did the BJ shares sell for in the Form 4 filing?

Shares were sold at weighted-average prices of $106.73, $107.27, and $108.03, covering a range of $105.98–$108.07.

How many BJ shares does the CEO still own after the sale?

He now owns 368,333 shares directly and 2,000 shares indirectly via dependent children.

Was the insider sale made under a Rule 10b5-1 plan?

The Form 4 does not indicate a Rule 10b5-1(c) trading plan; the corresponding checkbox is not marked.

What percentage of the CEO’s holdings were sold?

The sale represents approximately 4.6 % of his pre-transaction direct ownership.