Alnylam CEO granted 107 shares for 10-year service

ALNY CEO Yvonne Greenstreet reported a 107-share service award grant, bringing her direct holdings to 95,802 ALNY shares plus 407 indirect shares.

Rhea-AI Filing Summary

ALNYLAM PHARMACEUTICALS, INC. (symbol: ALNY) is the issuer of record for a Form 4 filing submitted to the SEC. Greenstreet Yvonne reported acquisition or exercise transactions in this Form 4 filing.

ALNYLAM PHARMACEUTICALS, INC. (ALNY) reported that Chief Executive Officer and director Yvonne Greenstreet received a grant of 107 shares of common stock on September 19, 2026 as a non-cash award recognizing 10 years of continuous employment, issued net of the minimum statutory tax liability. Following this award, she holds 95,802 shares directly and 407 shares indirectly through a managed account reflecting ALNY 401(k) matching contributions. No Rule 10b5-1 trading plan is reported.

Insider Trade Summary

Grant/Award: 107 shares

Grant/Award 2 txns

Insider Greenstreet Yvonne

Role Chief Executive Officer

Type	Security	Shares	Price	Value
Grant/Award	Common Stock F1	107	$0.00	$0.00
holding	Common Stock F2	--	--	--

Holdings After Transaction: Common Stock — 95,802 shares (Direct); Common Stock — 407 shares (Indirect, by Managed Account)

Footnotes (2)

1. F1. On February 23, 2016, the People, Culture, and Compensation Committee of the issuer approved the issuance of shares of Company common stock having an aggregate value of USD $50,000 to each employee who completes 10 consecutive years of employment. The shares issued and reported here on Form 4, net of the minimum statutory tax liability, were issued to the reporting person in recognition of 10 years of continuous employment on September 19, 2026.
2. F2. Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

Key Figures

Shares granted: 107 shares Service award aggregate value: $50,000 Direct holdings after transaction: 95,802 shares +2 more

5 metrics

Shares granted 107 shares Common stock granted on September 19, 2026 as a 10-year service award

Service award aggregate value $50,000 Approved value of shares issued to each employee completing 10 consecutive years

Direct holdings after transaction 95,802 shares ALNY common stock held directly by Yvonne Greenstreet after the grant

Indirect holdings after transaction 407 shares ALNY common stock held indirectly by managed account tied to 401(k)

Years of continuous employment 10 years Service period recognized by the September 19, 2026 award

Key Terms

non-derivative, minimum statutory tax liability, 401(k) plan, matching contribution program, +1 more

5 terms

non-derivative financial

"The transaction involves Common Stock reported as a non-derivative holding"

minimum statutory tax liability financial

"The shares issued and reported here were issued net of the minimum statutory tax liability"

401(k) plan financial

"Reflects shares of ALNY common stock acquired under the ALNY 401(k) plan"

A 401(k) plan is a workplace retirement account that lets employees set aside part of their pay into a tax-advantaged savings pot, often with employers adding matching contributions — like a workplace piggy bank for future income. It matters to investors because the amount people save and how employers fund these plans influence consumer spending, corporate payroll costs and the flow of money into financial markets, which can affect stock prices and company valuations.

matching contribution program financial

"Acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program"

People, Culture, and Compensation Committee financial

"On February 23, 2016, the People, Culture, and Compensation Committee of the issuer approved the issuance"

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What transaction did ALNY CEO Yvonne Greenstreet report on this Form 4 for ALNY?

She reported a grant of 107 shares of ALNY common stock on September 19, 2026, issued as a non-cash award in recognition of 10 years of continuous employment, net of the minimum statutory tax liability.

How many ALNY shares does Yvonne Greenstreet hold after this Form 4 transaction?

After the transaction, Yvonne Greenstreet holds 95,802 ALNY common shares directly and 407 shares indirectly through a managed account related to the ALNY 401(k) matching contribution program.

What is the value of the ALNY 10-year service award reported for Yvonne Greenstreet?

The People, Culture, and Compensation Committee approved issuing shares with an aggregate value of $50,000 to each employee completing 10 consecutive years of employment; the 107 shares reported here represent that award to Yvonne Greenstreet, issued net of statutory taxes.

Was Yvonne Greenstreet’s ALNY Form 4 transaction executed under a Rule 10b5-1 plan?

No. The filing indicates that no Rule 10b5-1 trading plan is reported for this transaction.

How were the indirect ALNY shares in Yvonne Greenstreet’s Form 4 acquired?

The 407 indirect ALNY shares are held by a managed account and reflect shares acquired under the ALNY 401(k) plan as a result of the company’s 401(k) matching contribution program.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Available on EDGAR 09/22/2026 - 04:07 PM Accepted by SEC EDGAR 09/22/2026 - 04:07 PM Learn about SEC filing dates

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Greenstreet Yvonne

(Last) (First) (Middle)

675 WEST KENDALL STREET

(Street)

CAMBRIDGE MASSACHUSETTS 02142

(City) (State) (Zip)

UNITED STATES

(Country)

2. Issuer Name and Ticker or Trading Symbol
ALNYLAM PHARMACEUTICALS, INC. [ ALNY ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	Chief Executive Officer

2a. Foreign Trading Symbol

3. Date of Earliest Transaction (Month/Day/Year)
09/19/2026

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	09/19/2026		A(1)		107	A	$0	95,802	D
Common Stock								407	I	by Managed Account(2)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. On February 23, 2016, the People, Culture, and Compensation Committee of the issuer approved the issuance of shares of Company common stock having an aggregate value of USD $50,000 to each employee who completes 10 consecutive years of employment. The shares issued and reported here on Form 4, net of the minimum statutory tax liability, were issued to the reporting person in recognition of 10 years of continuous employment on September 19, 2026.

2. Reflects shares of ALNY common stock acquired by the reporting person under the ALNY 401(k) plan as a result of the ALNY 401(k) matching contribution program.

	Brett Budzinski, Attorney-in-Fact For: Yvonne Greenstreet	09/22/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)