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Alx Oncology Holdings Inc SEC Filings

ALXO NASDAQ

Welcome to our dedicated page for Alx Oncology Holdings SEC filings (Ticker: ALXO), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.

CD47 blockade may be cutting-edge science, but deciphering the regulatory paperwork behind it is anything but simple. ALX Oncology’s filings pack dense clinical data, detailed R&D spending, and nuanced risk factors that can obscure crucial signals such as trial timelines or cash runway. If you have ever searched for ALX Oncology insider trading Form 4 transactions or wondered how the latest toxicology update might affect valuation, you know the challenge.

Stock Titan resolves that pain. Our platform delivers AI-powered summaries that translate every 10-K, 10-Q, 8-K, and proxy into plain language, turning “what does this mean?” into instant insight. Need the ALX Oncology quarterly earnings report 10-Q filing as soon as it hits EDGAR? We alert you in real time and layer in ALX Oncology earnings report filing analysis so you can spot shifts in cash burn. Curious about management confidence? Get ALX Oncology Form 4 insider transactions real-time and track each ALX Oncology executive stock transactions Form 4 with context. Our coverage spans every disclosure, from ALX Oncology 8-K material events explained to the ALX Oncology proxy statement executive compensation details that illuminate incentives.

That depth matters because biotech value turns on details: dosing cohorts, adverse-event tables, licensing clauses. Here you’ll find the ALX Oncology annual report 10-K simplified, plus tools for understanding ALX Oncology SEC documents with AI. Investors routinely use our platform to (i) monitor Phase data drops via 8-Ks, (ii) compare quarter-over-quarter R&D trends, and (iii) gauge confidence through insider buys or sells—all without wading through hundreds of pages. Complex science, clear filings.

Rhea-AI Summary

Morgan Stanley Finance LLC, guaranteed by Morgan Stanley, intends to issue Fixed-Income Buffered Auto-Callable Securities linked to the S&P 500 Futures 40% Intraday 4% Decrement VT Index (ticker SPXF40D4). The securities offer a fixed coupon of 7.00%-8.00% per annum paid monthly and mature on 1 August 2030, unless automatically redeemed earlier.

Auto-call feature: beginning 12 months after issuance and on each monthly determination date thereafter, the notes will be redeemed at par (plus the coupon) if the index closes at or above its initial level (100%). Once called, no further payments are due.

Downside protection: at maturity, investors receive full principal repayment so long as the index has not fallen by more than the 15% buffer. Below this threshold, repayment is reduced 1-for-1, exposing holders to up to an 85% maximum loss.

Pricing details: • Pricing date: 28 July 2025 • Settlement/Maturity: 1 Aug 2030 • Estimated value: $920.10 (± $55) per $1,000 face, reflecting issuance costs and Morgan Stanley’s internal models • CUSIP: 61778NBH3

Key risks called out by the issuer

  • No participation in any index appreciation beyond par.
  • Potential early redemption limits total coupon receipts.
  • Full exposure to Morgan Stanley credit risk; MSFL has no independent assets.
  • Index-specific risks: 4% annual decrement drag, leverage, short operating history (inception 30 Aug 2024).

Tax treatment and other detailed structural provisions are summarized in the preliminary pricing supplement (SEC link provided) and should be reviewed before investing.

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FAQ

What is the current stock price of Alx Oncology Holdings (ALXO)?

The current stock price of Alx Oncology Holdings (ALXO) is $0.4601 as of July 3, 2025.

What is the market cap of Alx Oncology Holdings (ALXO)?

The market cap of Alx Oncology Holdings (ALXO) is approximately 24.2M.

What is the core focus of ALX Oncology Holdings Inc.?

ALX Oncology is focused on developing innovative immuno-oncology therapies, particularly by targeting the CD47 immune checkpoint to help the immune system combat cancer.

How does evorpacept, the company’s lead candidate, work?

Evorpacept is a fusion protein that combines a high-affinity CD47 binding domain with an inactivated Fc region, designed to block the CD47 'don’t eat me' signal and enhance immune recognition of cancer cells.

What makes ALX Oncology’s approach to CD47 blockade unique?

The company’s approach uses an inactivated Fc domain to minimize hematologic toxicities, allowing for higher therapeutic dosing when used in combination with other anti-cancer agents.

In which areas is ALX Oncology conducting clinical studies?

ALX Oncology is engaged in clinical trials across various hematologic and solid malignancies, often exploring combination regimens with standard anticancer antibodies, ADCs, and checkpoint inhibitors.

How does ALX Oncology differentiate itself in the competitive immuno-oncology market?

ALX Oncology differentiates itself through its precise protein engineering, the unique safety profile of evorpacept, and its strategic focus on combination therapies that bridge innate and adaptive immunity.

What is the significance of targeting the CD47 checkpoint in cancer therapy?

Targeting the CD47 checkpoint is significant because it interrupts a key mechanism that cancer cells use to avoid immune detection, thereby potentially enhancing the efficacy of cancer treatments.

What role does combination therapy play in ALX Oncology’s research strategy?

Combination therapy is integral to their strategy as it aims to leverage the benefits of evorpacept alongside other anti-cancer agents, increasing therapeutic efficacy and addressing resistance mechanisms.

Who are the typical stakeholders interested in ALX Oncology’s developments?

Investors, clinicians, and researchers with an interest in cutting-edge immuno-oncology and targeted cancer therapies are the primary stakeholders following ALX Oncology’s clinical advancements.
Alx Oncology Holdings Inc

NASDAQ:ALXO

ALXO Rankings

ALXO Stock Data

24.19M
42.43M
2.03%
89.37%
11.03%
Biotechnology
Pharmaceutical Preparations
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United States
SOUTH SAN FRANCISCO