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Alto Neuroscience (ANRO) OKs ESPP amendment but rejects equity plan change

Filing Impact
(Moderate)
Filing Sentiment
(Neutral)
Form Type
8-K

Rhea-AI Filing Summary

Alto Neuroscience, Inc. reported results from its 2026 annual stockholder meeting. Of 31,945,516 common shares outstanding as of the record date, 26,762,809 shares, or about 83.77%, were represented, giving the company a strong quorum for voting.

Stockholders elected two Class II directors: Raymond Sanchez, M.D. received 23,133,161 votes for and 31,432 withheld, while Gwill York received 12,385,501 for and 10,779,092 withheld, with 3,598,216 broker non-votes for each. They ratified Deloitte & Touche LLP as independent registered public accounting firm for the year ending December 31, 2026, with 26,727,215 votes for. Stockholders did not approve an amendment and restatement of the 2024 Equity Incentive Plan related to treating pre-funded warrants like common shares for the plan’s evergreen share reserve, but did approve a similar amendment and restatement of the 2024 Employee Stock Purchase Plan.

Positive

  • None.

Negative

  • None.
Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers Governance
Key personnel changes including departures, elections, or appointments of directors and executive officers.
Item 5.07 Submission of Matters to a Vote of Security Holders Governance
Results of a shareholder vote on proposals at an annual or special meeting.
Item 9.01 Financial Statements and Exhibits Exhibits
Financial statements, pro forma financial information, and exhibit attachments filed with this report.
Shares outstanding record date 31,945,516 shares Common stock outstanding as of the record date
Shares represented at meeting 26,762,809 shares Approximately 83.77% of outstanding shares present or by proxy
Director vote – Raymond Sanchez 23,133,161 for / 31,432 withheld Class II director election; 3,598,216 broker non-votes
Director vote – Gwill York 12,385,501 for / 10,779,092 withheld Class II director election; 3,598,216 broker non-votes
Auditor ratification vote 26,727,215 for Deloitte & Touche LLP; 23,440 against, 12,154 abstentions
2024 Equity Plan amendment vote 10,838,509 for / 12,205,864 against Proposal not approved; 120,220 abstentions, 3,598,216 broker non-votes
A&R 2024 ESPP amendment vote 11,946,818 for / 11,097,535 against Proposal approved; 120,240 abstentions, 3,598,216 broker non-votes
Amended and Restated 2024 Employee Stock Purchase Plan financial
"the Company’s stockholders approved the Amended and Restated 2024 Employee Stock Purchase Plan (the “A&R 2024 ESPP”)."
evergreen feature financial
"for purposes of calculating the number of shares to be automatically added to the share reserve thereunder pursuant to the “evergreen” feature of the 2024 Plan."
pre-funded warrants financial
"to treat outstanding pre-funded warrants the same as outstanding shares of common stock for purposes of calculating the number of shares"
Pre-funded warrants are financial instruments that give investors the right to purchase a company's stock at a set price, but with most or all of the purchase price paid upfront. They function like a coupon or gift card for stock, allowing investors to buy shares later at a fixed price, which can be beneficial if they want to avoid future price increases. This makes them important for investors seeking flexibility and certainty in their investment plans.
independent registered public accounting firm financial
"ratified the selection of Deloitte & Touche LLP as the Company’s independent registered public accounting firm for the fiscal year ending December 31, 2026."
An independent registered public accounting firm is an outside accounting company officially registered with the government regulator to examine and report on a public company's financial records and controls. Investors treat its reports like an impartial inspector’s certificate — they add credibility to financial statements, help spot errors or misleading claims, and reduce the risk that shareholders are relying on unchecked or biased numbers.
broker non-votes financial
"The votes cast at the Annual Meeting regarding this proposal were as follows"
Broker non-votes occur when a brokerage firm is unable to vote on a shareholder’s behalf during a company election or decision because the shareholder has not given specific voting instructions, and the broker is not allowed or chooses not to vote on certain matters. They are important because they can affect the outcome of votes, especially when the results are close, by effectively reducing the total number of votes cast.
0001999480False00019994802026-05-122026-05-12

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
_____________________
FORM 8-K
_____________________

CURRENT REPORT
Pursuant to Section 13 or 15(d)
of the Securities Exchange Act of 1934

Date of Report (Date of earliest event reported): May 12, 2026
_____________________
ALTO NEUROSCIENCE, INC.
(Exact Name of Registrant as Specified in its Charter)
_____________________
Delaware
 001-41944
83-4210124
(State or Other Jurisdiction
of Incorporation)
(Commission
File Number)
(IRS Employer
Identification No.)
650 Castro Street, Suite 450, Mountain View, CA
94041
(Address of principal executive offices)(Zip Code)
Registrant’s telephone number, including area code: (650) 200-0412
N/A
(Former name or former address, if changed since last report)
_____________________
Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:
oWritten communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
oSoliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
oPre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
oPre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))


Securities registered pursuant to Section 12(b) of the Act:
Title of each classTrading
Symbol(s)
Name of each exchange
on which registered
Common Stock, $0.0001 par value per shareANRONew York Stock Exchange

Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§240.12b-2 of this chapter).
Emerging growth company x
If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. o



Item 5.02 Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.

(e) Equity Plan Amendments

As noted in Item 5.07 below, at the Alto Neuroscience, Inc. (the “Company”) 2026 annual meeting of stockholders (the “Annual Meeting”), the Company’s stockholders approved the Amended and Restated 2024 Employee Stock Purchase Plan (the “A&R 2024 ESPP”). The Company’s Board of Directors adopted the A&R 2024 ESPP on March 16, 2026. A full description of the A&R 2024 ESPP appears in the Company’s Definitive Proxy Statement on Schedule 14A (including the annex thereto) filed with the Securities and Exchange Commission on March 26, 2026 (the “Proxy Statement”) and is incorporated herein by reference. A copy of the A&R 2024 ESPP is attached hereto as Exhibit 10.1 and is incorporated herein by reference.
Item 5.07 Submission of Matters to a Vote of Security Holders.
On May 12, 2026, the Company held the Annual Meeting. The stockholders considered four proposals, each of which is described in more detail in the Proxy Statement. Of the 31,945,516 shares of common stock outstanding as of the record date, 26,762,809 shares, or approximately 83.77%, were present or represented by proxy at the Annual Meeting. Set forth below are the results of the matters submitted for a vote of stockholders at the Annual Meeting.

Proposal No. 1: Election of Directors

The Company’s stockholders approved the Class II director nominees recommended for election at the Annual Meeting to serve as directors until the 2029 annual meeting of stockholders and until the director’s successor has been duly elected and qualified. The votes cast at the Annual Meeting regarding this proposal were as follows:

NameVotes ForVotes WithheldBroker Non-Votes
Raymond Sanchez, M.D. 23,133,16131,4323,598,216
Gwill York12,385,50110,779,0923,598,216
Proposal 2: Ratification of the Selection of Independent Registered Public Accounting Firm

The Company’s stockholders ratified the selection of Deloitte & Touche LLP as the Company’s independent registered public accounting firm for the fiscal year ending December 31, 2026. The votes cast at the Annual Meeting regarding this proposal were as follows:

Votes ForVotes AgainstAbstentionsBroker Non-Votes
26,727,21523,44012,1540
Proposal No. 3: Amendment and Restatement of 2024 Equity Incentive Plan

The Company's stockholders did not approve the proposed amendment and restatement of the Company’s 2024 Equity Incentive Plan (the “2024 Plan”) to treat outstanding pre-funded warrants the same as outstanding shares of common stock for purposes of calculating the number of shares to be automatically added to the share reserve thereunder pursuant to the “evergreen” feature of the 2024 Plan. The votes cast at the Annual Meeting regarding this proposal were as follows:

Votes ForVotes AgainstAbstentionsBroker Non-Votes
10,838,50912,205,864120,2203,598,216
Proposal No. 4: Amendment and Restatement of 2024 Employee Stock Purchase Plan

The Company’s stockholders approved the proposed amendment and restatement of the Company’s 2024 Employee Stock Purchase Plan to treat outstanding pre-funded warrants the same as outstanding shares of common stock for purposes of calculating the number of shares to be automatically added to the share reserve thereunder pursuant to the “evergreen” feature of the A&R 2024 ESPP. The votes cast at the Annual Meeting regarding this proposal were as follows:




Votes ForVotes AgainstAbstentionsBroker Non-Votes
11,946,81811,097,535120,2403,598,216


Item 9.01    Financial Statements and Exhibits.

(d)Exhibits.
Exhibit No.Description
10.1+
Amended and Restated 2024 Employee Stock Purchase Plan
104Cover Page Interactive Data File (embedded within the Inline XBRL document)/
+ Indicates management contract or compensatory plan.



SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.
ALTO NEUROSCIENCE, INC.
Dated: May 13, 2026By:/s/ Amit Etkin
Amit Etkin, M.D., Ph.D.
President and Chief Executive Officer

FAQ

What did Alto Neuroscience (ANRO) stockholders approve at the 2026 annual meeting?

Stockholders approved changes to the 2024 Employee Stock Purchase Plan and ratified Deloitte & Touche LLP as independent auditor for 2026. They also elected two Class II directors to serve until the 2029 annual stockholder meeting.

How many Alto Neuroscience (ANRO) shares were represented at the annual meeting?

A total of 26,762,809 shares were present or represented by proxy, out of 31,945,516 common shares outstanding as of the record date. This represented approximately 83.77% of outstanding shares and provided a solid quorum for voting.

Were Alto Neuroscience’s 2024 equity incentive plan changes approved?

No. Stockholders did not approve the amendment and restatement of the 2024 Equity Incentive Plan that would have treated outstanding pre-funded warrants like common shares for calculating automatic additions to the plan’s evergreen share reserve.

What change to Alto Neuroscience’s employee stock purchase plan was approved?

Stockholders approved an amended and restated 2024 Employee Stock Purchase Plan. The change treats outstanding pre-funded warrants the same as common shares when calculating automatic additions to the share reserve under the plan’s evergreen feature, aligning treatment of these instruments.

Which directors were elected at Alto Neuroscience’s 2026 meeting and how did they fare?

Class II nominees Raymond Sanchez, M.D. and Gwill York were elected. Sanchez received 23,133,161 votes for and 31,432 withheld, while York received 12,385,501 for and 10,779,092 withheld, with 3,598,216 broker non-votes for each.

Who will serve as Alto Neuroscience’s independent auditor for 2026?

Deloitte & Touche LLP was ratified as Alto Neuroscience’s independent registered public accounting firm for the fiscal year ending December 31, 2026. The vote was 26,727,215 for, 23,440 against, and 12,154 abstentions, with no broker non-votes recorded.

Filing Exhibits & Attachments

4 documents