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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, DC 20549
FORM 8-K
CURRENT REPORT
Pursuant to Section 13 or 15(d) of the
Securities Exchange Act of 1934
Date of report (Date
of earliest event reported): May 20, 2026
ANNOVIS BIO, INC.
(Exact Name of Registrant as Specified in Charter)
| Delaware |
001-39202 |
26-2540421 |
|
(State or Other Jurisdiction
of Incorporation) |
(Commission
File Number) |
(I.R.S. Employer
Identification No.) |
101
Lindenwood Drive, Suite 225
Malvern, PA
19355
(Address of Principal Executive Offices, and
Zip Code)
(484) 875-3192
Registrant’s Telephone Number, Including
Area Code
Not
Applicable
(Former Name or Former Address, if Changed Since
Last Report)
Securities registered pursuant to Section 12(b)
of the Act:
| Title of each class |
Trading Symbol(s) |
Name
of each exchange on which
registered |
| Common Stock, par value $0.0001 per share |
ANVS |
New York Stock Exchange |
Check the appropriate box below if the Form 8-K filing is intended
to simultaneously satisfy the filing obligation of the registrant under any of the following provisions (see General Instruction
A.2. below):
| |
¨ |
Written communication pursuant to Rule 425 under the Securities Act (17 CFR 230.425) |
| |
¨ |
Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12) |
| |
¨ |
Pre-commencement communication pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b)) |
| ¨ | Pre-commencement communication pursuant to Rule 13e-4(c) under
the Exchange Act (17 CFR 240.13e-4(c)) |
Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (17 CFR §230.405) or Rule 12b-2 of the Securities Exchange Act of 1934 (17 CFR §240.12b-2).
Emerging growth company ¨
If an emerging growth company,
indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised
financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ¨
| Item 1.01 |
Entry into a Material Definitive Agreement. |
On May 20, 2026, Annovis Bio, Inc. (the “Company”) entered into an Underwriting Agreement (the “Underwriting Agreement”),
dated as of May 20, 2026, with Canaccord Genuity LLC, as underwriter (the “Underwriter”), pursuant to which the Company agreed
to issue and sell, in a public offering (the “Offering”) (i) an aggregate of 7,895,000 shares of common stock (the “Shares”),
$0.0001 par value per share (the “Common Stock”), of the Company and (ii) accompanying common stock warrants to purchase up
to an aggregate of 7,105,500 shares of Common Stock (the “Warrants” and the shares of Common Stock issuable upon exercise
of the Warrants, the “Warrant Shares”). The Warrants are immediately exercisable, expire six years from the date of issuance
and have an exercise price equal to $2.25 per share of Common Stock. The combined offering price of each Share and accompanying nine-tenths
of a Warrant is $1.90 per share. The gross proceeds to the Company from the Offering are expected to be approximately $15 million, before
deducting offering expenses payable by the Company.
The Offering is expected to close on or about
May 21, 2026, subject to the satisfaction of customary closing conditions. The Company currently plans to use the net proceeds from the
Offering, for the continued clinical development of the Company’s lead compound Buntanetap in clinical studies for for Alzheimer’s
disease and Parkinson’s disease, and for working capital and general corporate purposes.
The Underwriting Agreement contains customary
representations, warranties and agreements by the Company, customary conditions to closing, indemnification obligations of the Company,
including for liabilities arising under the Securities Act of 1933, as amended (the “Securities Act”), other obligations of
the parties and termination provisions. The representations, warranties and covenants contained in the Underwriting Agreement were made
only for the purposes of such agreement and as of the specific dates, were solely for the benefit of the parties to such agreement and
may be subject to limitations agreed upon by the contracting parties.
The Offering was made pursuant to the Company’s
effective shelf registration statement on Form S-3 (File No. 333-276814), which was declared effective on February 12,
2024, and a related base prospectus and prospectus supplement thereunder dated May 19, 2026.
The legal opinion of Loeb & Loeb LLP relating
to the Shares, Warrants and Warrant Shares is filed herewith as Exhibit 5.1.
The foregoing description of the terms and conditions
of the Undewriting Agreement and the Warrant do not purport to be complete and are qualified in its entirety by the full text of
each of such document, copies of which are attached hereto as Exhibits 10.1 and 4.1, respectively, and incorporate by reference
herein.
| Item 7.01 |
Regulation FD Disclosure |
On May 19, 2026, the Company issued a press release announcing the
launch of the Offering. On May 20, 2026, the Company issued a press release announcing the pricing of the Offering. Copies of the press
releases are furnished as Exhibits 99.1 and 99.2 to this Current Report on Form 8-K and is incorporated by reference herein.
The information contained in this Item 7.01 shall
not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”),
or incorporated by reference in any filing under the Securities Act or the Exchange Act, except as shall be expressly set forth by specific
reference in such a filing.
| Item 9.01 |
Financial Statements and Exhibits |
| Exhibit Number |
|
Description |
| |
|
|
| 4.1 |
|
Form of Warrant |
| |
|
|
| 5.1 |
|
Opinion of Loeb & Loeb LLP |
| |
|
|
| 10.1 |
|
Underwriting Agreement |
| |
|
|
| 23.1 |
|
Consent of Loeb & Loeb LLP (contained in Exhibit 5.1) |
| |
|
|
| 99.1 |
|
Press Release, dated May 19, 2026 |
| |
|
|
| 99.2 |
|
Press Release, dated May 20, 2026 |
| |
|
|
| 104 |
|
Cover Page Interactive Data File (embedded within the Inline XBRL document) |
SIGNATURES
Pursuant to the requirements of the Securities
Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.
| |
ANNOVIS BIO, INC. |
| |
|
| Date: May 20, 2026 |
By: |
/s/ Maria Maccecchini |
| |
|
Name: |
Maria Maccecchini |
| |
|
Title: |
President and Chief Executive Officer |
Exhibit 99.1
Annovis
Announces Launch of Proposed Public Offering of Common Stock and Accompanying Warrants
MALVERN,
Pa., May 19, 2026 -- Annovis Bio, Inc. (NYSE: ANVS) (“Annovis” or the “Company”), a Phase 3 clinical-stage
biotechnology company developing the investigational oral therapy, buntanetap, for neurodegenerative diseases such as Alzheimer's disease
(AD) and Parkinson's disease (PD), today announced a proposed underwritten public offering in which it intends to offer and sell
(i) shares of its common stock and (ii) accompanying warrants to purchase shares of common stock. The shares of common stock and the
accompanying warrants will be issued separately but can only be purchased together in the proposed offering. All of the shares of common
stock and the accompanying warrants will be offered by Annovis. The proposed offering is subject to market and other conditions, and
there can be no assurance as to whether or when the offering may be completed, or as to the actual size or terms of the offering.
Canaccord Genuity is acting as the sole bookrunner
in the offering.
Annovis intends to use the net proceeds from
the offering for the continued clinical development of its lead compound buntanetap in a Phase 3 study for Alzheimer’s disease
(AD), and for working capital and general corporate purposes.
The
shares and the accompanying warrants are being offered by Annovis pursuant to an effective shelf registration statement on Form S-3 (No.
333-276814) previously filed with the Securities and Exchange Commission (SEC) on February 1, 2024 and declared effective by the SEC
on February 12, 2024. A preliminary prospectus supplement and accompanying prospectus describing the terms of the proposed offering will
be filed with the SEC. When available, copies of the preliminary prospectus supplement and the accompanying prospectus relating to this
offering may be obtained from: Canaccord Genuity LLC, Attention: Syndication Department, One Post Office Square, 30th Floor, Boston,
Massachusetts 02109, or by email at prospectus@cgf.com. Electronic copies of the preliminary prospectus supplement and
accompanying prospectus will also be available on the SEC’s website at http://www.sec.gov.
This press release does not constitute an offer to sell or the solicitation
of an offer to buy the securities, nor shall there be any sale of the securities in any state or other jurisdiction in which such offer,
solicitation or sale would be unlawful prior to the registration or qualification under the securities laws of such state or other jurisdiction.
About Annovis
Headquartered in Malvern, Pennsylvania, Annovis Bio, Inc. (NYSE: ANVS)
is a Phase 3 clinical-stage biotechnology company developing treatments for neurodegenerative diseases such as Alzheimer's disease (AD)
and Parkinson's disease (PD). The Company's lead drug candidate, buntanetap (formerly posiphen), is an investigational once-daily oral
therapy that inhibits the translation of multiple neurotoxic proteins, including APP and amyloid beta, tau, alpha-synuclein, and TDP-43,
through a specific RNA-targeting mechanism of action. By addressing the underlying causes of neurodegeneration, Annovis aims to halt
disease progression and improve cognitive and motor functions in patients. For more information, visit www.annovisbio.com and follow
us on LinkedIn, YouTube, and X.
Forward-Looking Statements
This press release contains forward-looking statements under the Securities
Act of 1933 and the Securities Exchange Act of 1934, as amended, including, without limitation, statements regarding the consummation
of the offering, the satisfaction of closing conditions and the intended use of proceeds from the offering. Actual results may differ
due to various risks and uncertainties, including those outlined in the Company’s SEC filings under “Risk Factors”
in its Annual Report on Form 10-K and Quarterly Reports on Form 10-Q. The Company undertakes no obligation to update forward-looking
statements except as required by law.
Contact Information:
Annovis Bio Inc.
101 Lindenwood Drive
Suite 225
Malvern, PA 19355
www.annovisbio.com
Investor Contact:
Alexander Morin, Ph.D.
Director, Strategic Communications
Annovis Bio
ir@annovisbio.com
Exhibit 99.2
Annovis
Announces Pricing of $15.0 Million Public Offering of Common Stock and Accompanying Warrants
MALVERN, Pa., May 20, 2026 --
Annovis Bio, Inc. (NYSE: ANVS) (“Annovis” or the “Company”), a Phase 3 clinical-stage biotechnology company developing
the investigational oral therapy, buntanetap, for neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease
(PD), today announced the pricing of an underwritten public offering of 7,895,000 shares of its common stock and accompanying warrants
to purchase up to 7,105,500 shares of common stock. The combined offering price of each share of common stock and accompanying warrant
is $1.90. Each warrant will be exercisable for one share of common stock at an exercise price of $2.25 per share of common stock, will
be exercisable immediately following the issue date and will expire six years after the date of issuance.
All of the shares of common stock and the
accompanying warrants are being offered by Annovis. The shares of common stock and the accompanying warrant will be issued separately
but can only be purchased together in the offering.
Before deducting the underwriting discounts
and commissions and other offering expenses, Annovis expects to receive total gross proceeds of approximately $15.0 million, excluding
potential proceeds from the exercise of the warrants. The offering is expected to close on or about May 21, 2026, subject to the satisfaction
of customary closing conditions.
Canaccord Genuity is acting as the sole bookrunner
in the offering.
Annovis intends to use the net proceeds from
the offering for the continued clinical development of its lead compound buntanetap in clinical studies for Alzheimer’s disease
(AD) and Parkinson’s Disease (PD) and for working capital and general corporate purposes.
The shares and the accompanying warrants
are being offered by Annovis pursuant to an effective shelf registration statement on Form S-3 (No. 333-276814) previously filed with
the Securities and Exchange Commission (SEC) on February 1, 2024 and declared effective by the SEC on February 12, 2024. A final prospectus
supplement and accompanying prospectus describing the terms of the offering will be filed with the SEC. When available, copies of the
final prospectus supplement and the accompanying prospectus relating to this offering may be obtained from: Canaccord Genuity LLC, Attention:
Syndication Department, One Post Office Square, 30th Floor, Boston, Massachusetts 02109, or by email at prospectus@cgf.com. Electronic
copies of the final prospectus supplement and accompanying prospectus will also be available on the SEC’s website at http://www.sec.gov.
This press release does not constitute an
offer to sell or the solicitation of an offer to buy the securities, nor shall there be any sale of the securities in any state or other
jurisdiction in which such offer, solicitation or sale would be unlawful prior to the registration or qualification under the securities
laws of such state or other jurisdiction.
About Annovis
Headquartered in Malvern, Pennsylvania, Annovis Bio, Inc. (NYSE: ANVS)
is a Phase 3 clinical-stage biotechnology company developing treatments for neurodegenerative diseases such as Alzheimer's disease (AD)
and Parkinson's disease (PD). The Company's lead drug candidate, buntanetap (formerly posiphen), is an investigational once-daily oral
therapy that inhibits the translation of multiple neurotoxic proteins, including APP and amyloid beta, tau, alpha-synuclein, and TDP-43,
through a specific RNA-targeting mechanism of action. By addressing the underlying causes of neurodegeneration, Annovis aims to halt
disease progression and improve cognitive and motor functions in patients. For more information, visit www.annovisbio.com and
follow us on LinkedIn, YouTube, and X.
Forward-Looking Statements
This press release contains forward-looking statements under the Securities
Act of 1933 and the Securities Exchange Act of 1934, as amended, including, without limitation, statements regarding the consummation
of the offering, the satisfaction of closing conditions and the intended use of proceeds from the offering. Actual results may differ
due to various risks and uncertainties, including those outlined in the Company’s SEC filings under “Risk Factors” in
its Annual Report on Form 10-K and Quarterly Reports on Form 10-Q. The Company undertakes no obligation to update forward-looking statements
except as required by law.
Contact Information:
Annovis Bio Inc.
101 Lindenwood Drive
Suite 225
Malvern, PA 19355
www.annovisbio.com
Investor Contact:
Alexander Morin, Ph.D.
Director, Strategic Communications
Annovis Bio
ir@annovisbio.com