STOCK TITAN

Apogee Therapeutics (APGE) CMO trades stock under Rule 10b5-1 plan

Filing Impact
(Very High)
Filing Sentiment
(Negative)
Form Type
4

Rhea-AI Filing Summary

Apogee Therapeutics, Inc. Chief Medical Officer Carl Dambkowski reported an option exercise and related stock sale. He exercised stock options covering 4,125 shares of common stock at $22.86 per share, then sold 5,500 shares in an open-market transaction at $78.71 per share.

Following these transactions, he directly holds 205,648 shares of common stock and retains stock options representing the right to purchase 118,915 shares, expiring on December 18, 2033. The sale was executed under a pre-arranged Rule 10b5-1 trading plan adopted on September 22, 2025, and represents a small portion of his overall holdings.

Positive

  • None.

Negative

  • None.
Insider Dambkowski Carl
Role Chief Medical Officer
Sold 5,500 shs ($433K)
Type Security Shares Price Value
Exercise Stock Option (Right to Buy) 4,125 $0.00 --
Exercise Common Stock 4,125 $22.86 $94K
Sale Common Stock 5,500 $78.71 $433K
Holdings After Transaction: Stock Option (Right to Buy) — 118,915 shares (Direct, null); Common Stock — 211,148 shares (Direct, null)
Footnotes (1)
  1. This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on September 22, 2025. This option represents the right to purchase 175,345 shares of the Issuer's common stock, which will vest in forty-eight equal monthly installments through December 18, 2027, subject to the Reporting Person's continued service to the Issuer.
Shares sold 5,500 shares Open-market sale of common stock at $78.71 on June 3, 2026
Sale price $78.71/share Price per share for 5,500 common shares sold
Options exercised 4,125 shares Stock options converted into common stock at $22.86
Option strike price $22.86/share Exercise price for 4,125 stock options
Common shares held 205,648 shares Direct ownership after sale on June 3, 2026
Remaining option rights 118,915 shares Stock Option (Right to Buy) after exercise, expiring December 18, 2033
Option expiration December 18, 2033 Expiration date of stock option grant
10b5-1 plan adoption September 22, 2025 Adoption date of Rule 10b5-1 trading plan governing the sale
Rule 10b5-1 trading plan financial
"This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on September 22, 2025."
A Rule 10b5-1 trading plan is a pre-arranged schedule that allows company insiders to buy or sell stock at specific times, even if they have inside information. It helps prevent accusations of unfair trading by making these transactions look planned and transparent, rather than sneaky or illegal.
open-market sale financial
"transaction_action: open-market sale, transaction_code_description: Sale in open market or private transaction"
An open-market sale is when a shareholder sells existing shares directly on a public exchange to any willing buyer, rather than through a private deal. Think of it like putting goods on a busy market stall where price is set by supply and demand; for investors it matters because such sales increase available supply, can put short-term downward pressure on the stock price, and signal changes in liquidity or investor confidence.
Stock Option (Right to Buy) financial
"security_title: Stock Option (Right to Buy) with underlying security title Common Stock"
vest in forty-eight equal monthly installments financial
"which will vest in forty-eight equal monthly installments through December 18, 2027, subject to the Reporting Person's continued service"
expiration date financial
"expiration_date: 2033-12-18T00:00:00.000Z for the stock option grant"
The expiration date is the deadline after which a financial contract, such as an option or a futures agreement, is no longer valid or can be exercised. It matters to investors because it determines the timeframe during which they can take action or benefit from the contract, similar to how a coupon or a food item has a limited period of usefulness. Once the expiration date passes, the contract loses its value or ability to be used.
See more from StockTitan in Google Search and AI answers. Adds StockTitan as a preferred source · opens Google
Add on Google
SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
X
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
Dambkowski Carl

(Last)(First)(Middle)
C/O APOGEE THERAPEUTICS, INC.
221 CRESCENT ST., BLDG. 17, STE. 102B

(Street)
WALTHAM MASSACHUSETTS 02453

(City)(State)(Zip)

UNITED STATES

(Country)
2. Issuer Name and Ticker or Trading Symbol
Apogee Therapeutics, Inc. [ APGE ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
Director10% Owner
XOfficer (give title below)Other (specify below)
Chief Medical Officer
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
06/03/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Common Stock06/03/2026M4,125A$22.86211,148D
Common Stock06/03/2026S(1)5,500D$78.71205,648D
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Stock Option (Right to Buy)$22.8606/03/2026M4,125 (2)12/18/2033Common Stock4,125$0.00118,915D
Explanation of Responses:
1. This transaction was executed pursuant to a Rule 10b5-1 trading plan adopted on September 22, 2025.
2. This option represents the right to purchase 175,345 shares of the Issuer's common stock, which will vest in forty-eight equal monthly installments through December 18, 2027, subject to the Reporting Person's continued service to the Issuer.
/s/ Matthew Batters, as attorney-in-fact for Carl Dambkowski06/05/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)

FAQ

What did Apogee Therapeutics (APGE) insider Carl Dambkowski do in this Form 4?

Carl Dambkowski, Chief Medical Officer of Apogee Therapeutics, exercised stock options for 4,125 shares at $22.86 and sold 5,500 shares at $78.71. After these transactions, he continues to hold 205,648 common shares plus a large remaining option position.

How many Apogee Therapeutics (APGE) shares did the CMO sell and at what price?

The Chief Medical Officer sold 5,500 shares of Apogee Therapeutics common stock at an average price of $78.71 per share. This open-market sale occurred on June 3, 2026 and involved only a small fraction of his total shareholdings.

What stock options did the Apogee Therapeutics (APGE) CMO exercise in this filing?

He exercised stock options covering 4,125 shares of Apogee Therapeutics common stock at a strike price of $22.86 per share. These options are part of a larger grant that vests monthly through December 18, 2027, tied to his continued service.

How many Apogee Therapeutics (APGE) shares does the CMO hold after the reported transactions?

After the reported transactions, the Chief Medical Officer directly owns 205,648 shares of Apogee Therapeutics common stock. This figure reflects the net position following the option exercise and subsequent sale of 5,500 shares on the same transaction date.

What option position does the Apogee Therapeutics (APGE) CMO retain after exercising options?

Following the exercise, he retains stock options representing the right to purchase 118,915 shares of Apogee Therapeutics common stock. These options expire on December 18, 2033 and vest in forty-eight equal monthly installments through December 18, 2027.

Was the Apogee Therapeutics (APGE) insider sale made under a Rule 10b5-1 plan?

Yes. The open-market sale of 5,500 shares was executed pursuant to a Rule 10b5-1 trading plan adopted on September 22, 2025. Such plans pre-schedule trades, making the timing more routine rather than a discretionary market-timing decision.