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Adaptin Bio, Inc. reported that its common shares have been approved for quotation on the OTCQB Venture Market under the ticker symbol APTN. The company expects trading to begin in approximately 6–8 weeks and plans to share any material updates as they occur.
Adaptin is a biotechnology company developing precision cancer therapeutics focused on hard-to-reach tissues, including the brain. Its lead candidate, APTN-101, a brain bispecific T cell engager built on the BRiTE delivery platform, is FDA-cleared for a Phase 1 clinical trial in glioblastoma and has shown anti-tumor activity and a favorable safety profile in multiple preclinical models.
Adaptin Bio, Inc. is an early-stage biopharmaceutical company developing its BRiTE platform to deliver therapeutics across the blood-brain barrier, with lead candidate APTN-101 targeting EGFRvIII-positive glioblastoma and other cancers. The company completed a merger with Unite Acquisition 1 Corp. in February 2025, becoming a public entity.
For the year ended December 31, 2025, Adaptin reported a net loss of $5.17 million and an accumulated deficit of $9.29 million. Cash and cash equivalents were $459,174, leading management to state substantial doubt about its ability to fund operations for the next twelve months without new capital. Operations are funded primarily through private placements and prior bridge notes that converted into equity.
The company holds an exclusive license from Duke University covering its BRiTE technology, owes clinical and commercial milestones totaling up to $11.7 million plus royalties, and relies on contract manufacturers and sponsored research at Duke. As of March 26, 2026, Adaptin had 8,786,229 common shares outstanding and an approximate non-affiliate equity market value of $9.3 million, with no active trading market for its stock.