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ARK Investment Management LLC and Catherine D. Wood report a 9.19% beneficial stake in Arcturus Therapeutics Holdings Inc. common stock. As of December 31, 2025, they together report ownership of 2,611,099 shares, with ARK holding sole voting and dispositive power over these shares.
Catherine D. Wood reports shared voting and dispositive power over the same 2,611,099 shares. The filing states the securities are held in the ordinary course of business and not for the purpose of changing or influencing control of Arcturus. ARK Genomic Revolution ETF is noted as a client with an interest exceeding 5% of the class.
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13G
UNDER THE SECURITIES EXCHANGE ACT OF 1934
(Amendment No. 9)
Arcturus Therapeutics Holdings Inc.
(Name of Issuer)
Common Stock
(Title of Class of Securities)
03969T109
(CUSIP Number)
12/31/2025
(Date of Event Which Requires Filing of this Statement)
Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
Rule 13d-1(b)
Rule 13d-1(c)
Rule 13d-1(d)
SCHEDULE 13G
CUSIP No.
03969T109
1
Names of Reporting Persons
ARK Investment Management LLC
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
2,611,099.00
6
Shared Voting Power
0.00
7
Sole Dispositive Power
2,611,099.00
8
Shared Dispositive Power
0.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
2,611,099.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
9.19 %
12
Type of Reporting Person (See Instructions)
IA
SCHEDULE 13G
CUSIP No.
03969T109
1
Names of Reporting Persons
Catherine D. Wood
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
UNITED STATES
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
2,611,099.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
2,611,099.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
2,611,099.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
9.19 %
12
Type of Reporting Person (See Instructions)
HC, IN
SCHEDULE 13G
Item 1.
(a)
Name of issuer:
Arcturus Therapeutics Holdings Inc.
(b)
Address of issuer's principal executive offices:
10285 Science Center Drive, San Diego, CA 92121
Item 2.
(a)
Name of person filing:
(i) ARK Investment Management LLC ("ARK")
(ii) Catherine D. Wood
(b)
Address or principal business office or, if none, residence:
ARK and Catherine D. Wood: 200 Central Avenue, St. Petersburg, FL 33701
(c)
Citizenship:
(i) ARK: Delaware
(ii) Catherine D. Wood: United States
(d)
Title of class of securities:
Common Stock
(e)
CUSIP No.:
03969T109
Item 3.
If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)
Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)
Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)
Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)
Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)
An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)
An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)
A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)
A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)
A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)
A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J),
please specify the type of institution:
(k)
Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.
Ownership
(a)
Amount beneficially owned:
ARK and Catherine D. Wood: 2,611,099
(b)
Percent of class:
ARK and Catherine D. Wood: 9.19
(c)
Number of shares as to which the person has:
(i) Sole power to vote or to direct the vote:
(i) ARK: 2,611,099
(ii) Catherine D. Wood: 0
(ii) Shared power to vote or to direct the vote:
(i) ARK: 0
(ii) Catherine D. Wood: 2,611,099
(iii) Sole power to dispose or to direct the disposition of:
(i) ARK: 2,611,099
(ii) Catherine D. Wood: 0
(iv) Shared power to dispose or to direct the disposition of:
(i) ARK: 0
(ii) Catherine D. Wood: 2,611,099
Item 5.
Ownership of 5 Percent or Less of a Class.
Not Applicable
Item 6.
Ownership of more than 5 Percent on Behalf of Another Person.
If any other person is known to have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, such securities, a statement to that effect should be included in response to this item and, if such interest relates to more than 5 percent of the class, such person should be identified. A listing of the shareholders of an investment company registered under the Investment Company Act of 1940 or the beneficiaries of employee benefit plan, pension fund or endowment fund is not required.
No client of ARK Investment Management LLC currently has an interest in the securities reported herein in excess of 5 percent except ARK Genomic Revolution ETF, a series of a Delaware statutory trust.
Item 7.
Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
Not Applicable
Item 8.
Identification and Classification of Members of the Group.
Not Applicable
Item 9.
Notice of Dissolution of Group.
Not Applicable
Item 10.
Certifications:
By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.
SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.
ARK Investment Management LLC
Signature:
/s/ Kellen Carter
Name/Title:
Kellen Carter, Chief Compliance Officer
Date:
02/03/2026
Catherine D. Wood
Signature:
/s/ Catherine D. Wood
Name/Title:
Catherine D. Wood, Chief Executive Officer, Chief Investment Officer
