State Street reports 13.6M-share (5.5%) stake in Ardelyx

State Street Corporation reported beneficial ownership of 13,604,307 shares of Ardelyx, Inc. common stock, representing 5.5% of the class.

Rhea-AI Filing Summary

State Street Corporation reported beneficial ownership of 13,604,307 shares of Ardelyx, Inc. common stock, representing 5.5% of the class. The filing shows shared voting power of 12,897,628 shares and shared dispositive power of 13,604,307 shares, with ownership reported on behalf of multiple State Street advisory subsidiaries.

Insights

Institutional Ownership Analyst

Large passive holder reports a 5.5% stake via advisory entities.

State Street Corporation states beneficial ownership of 13,604,307 shares (5.5%), with shared voting power of 12,897,628 shares. The position is held through multiple advisory subsidiaries named in the filing.

Because this is a Schedule 13G disclosure, it reflects passive investment reporting rather than an active control intent; subsequent filings would show any change in status.

Corporate Governance Specialist

Shared authority via advisory vehicles is disclosed; no sole voting or dispositive power claimed.

The filing records zero sole voting and sole dispositive power while listing shared powers; several State Street advisory subsidiaries are identified as holders. This allocation signals fiduciary/advisory custody structure rather than individual control.

Future Forms 13D or 13G amendments would reveal material changes in intent, concentration, or control claims.

Key Figures

Beneficial ownership: 13,604,307 shares Percent of class: 5.5% Shared voting power: 12,897,628 shares +2 more

5 metrics

Beneficial ownership 13,604,307 shares Amount beneficially owned reported in Item 4

Percent of class 5.5% Percent of common stock represented by 13,604,307 shares

Shared voting power 12,897,628 shares Shared power to vote reported in Item 4

Shared dispositive power 13,604,307 shares Shared power to dispose reported in Item 4

Signature date 05/12/2026 Filing signature date

Key Terms

Schedule 13G, Shared dispositive power, Beneficial ownership, Advisory subsidiaries

4 terms

Schedule 13G regulatory

"Item 1. (a) Name of issuer: ARDELYX INC"

A Schedule 13G is a formal document that investors file with the government when they acquire a large ownership stake in a company, usually for investment purposes rather than control. It helps keep the public informed about who owns significant parts of a company's shares, which can influence how the company is managed and how investors make decisions. Filing this schedule is important for transparency and understanding the ownership landscape of publicly traded companies.

Shared dispositive power financial

"Item 4. (c)(iv) Shared power to dispose or to direct the disposition of: 13,604,307"

Beneficial ownership financial

"Item 4. (a) Amount beneficially owned: 13604307.00"

Beneficial ownership means the person or entity that actually enjoys the benefits of owning shares or other assets — such as receiving dividends, voting rights, or price gains — even if the legal title is held in another name. For investors it matters because knowing who truly controls and profits from a company reveals who can influence decisions, exposes potential conflicts of interest or hidden concentration of power, and affects transparency and risk in the stock.

Advisory subsidiaries other

"Item 7. SSGA FUNDS MANAGEMENT, INC.; STATE STREET GLOBAL ADVISORS EUROPE LIMITED"

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What stake does State Street (ARDX) report in Ardelyx?

State Street reports beneficial ownership of 13,604,307 shares, representing 5.5% of Ardelyx common stock. The position is reported as held through multiple State Street advisory subsidiaries and is shown with shared voting and dispositive powers.

Does State Street report sole voting control of ARDX shares?

No. The filing shows 0 sole voting power and 12,897,628 shared voting power. It indicates voting authority is shared among State Street entities rather than held solely by State Street Corporation.

Which State Street entities are identified as holders of ARDX shares?

The filing lists advisory subsidiaries including SSGA Funds Management, Inc., State Street Global Advisors Europe Limited, and others. These entities are named as the subsidiaries through which the shares are held on behalf of clients.

What date and signature appear on the 13G filing for ARDX?

The filing is signed by Elizabeth Schaefer, Senior Vice President, Chief Accounting Officer, with the signature date of 05/12/2026. The issuer address is included for Ardelyx, Inc.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Accepted by SEC EDGAR 05/12/2026 - 09:55 AM Learn about SEC filing dates

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

ARDELYX INC

(Name of Issuer)

COMMON STOCK

(Title of Class of Securities)

039697107

(CUSIP Number)

03/31/2026

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

Rule 13d-1(b)

Rule 13d-1(c)

Rule 13d-1(d)

schemaVersion:

SCHEDULE 13G

CUSIP Number(s): 039697107

1

Names of Reporting Persons

STATE STREET CORPORATION

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

MASSACHUSETTS

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 12,897,628.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 13,604,307.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

13,604,307.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

5.5 %

12

Type of Reporting Person (See Instructions)

HC

SCHEDULE 13G

Item 1.
(a)	Name of issuer: ARDELYX INC
(b)	Address of issuer's principal executive offices: 34175 ARDENWOOD BLVD SUITE 200, FREMONT, CALIFORNIA, 94555
Item 2.
(a)	Name of person filing: STATE STREET CORPORATION;
(b)	Address or principal business office or, if none, residence: ONE CONGRESS STREET, SUITE 1, BOSTON MA 02114, UNITED STATES
(c)	Citizenship: MA
(d)	Title of class of securities: COMMON STOCK
(e)	CUSIP Number(s): 039697107
Item 3.	If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)	Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)	Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)	Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)	Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)	An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)	An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)	A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)	A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)	A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)	A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:
(k)	Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.	Ownership
(a)	Amount beneficially owned: 13604307.00
(b)	Percent of class: 5.5 %
(c)	Number of shares as to which the person has:
	(i) Sole power to vote or to direct the vote: 0
	(ii) Shared power to vote or to direct the vote: 12,897,628
	(iii) Sole power to dispose or to direct the disposition of: 0
	(iv) Shared power to dispose or to direct the disposition of: 13,604,307
Item 5.	Ownership of 5 Percent or Less of a Class.
	Not Applicable
Item 6.	Ownership of more than 5 Percent on Behalf of Another Person.
	If any other person is known to have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, such securities, a statement to that effect should be included in response to this item and, if such interest relates to more than 5 percent of the class, such person should be identified. A listing of the shareholders of an investment company registered under the Investment Company Act of 1940 or the beneficiaries of employee benefit plan, pension fund or endowment fund is not required. NOT APPLICABLE
Item 7.	Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
	If a parent holding company has filed this schedule, pursuant to Rule 13d-1(b)(ii)(G), so indicate under Item 3(g) and attach an exhibit stating the identity and the Item 3 classification of the relevant subsidiary. If a parent holding company has filed this schedule pursuant to Rule 13d-1(c) or Rule 13d-1(d), attach an exhibit stating the identification of the relevant subsidiary. SSGA FUNDS MANAGEMENT, INC. (IA);STATE STREET GLOBAL ADVISORS EUROPE LIMITED (IA);STATE STREET GLOBAL ADVISORS LIMITED (IA);STATE STREET GLOBAL ADVISORS TRUST COMPANY (IA);STATE STREET GLOBAL ADVISORS, LTD. (IA);
Item 8.	Identification and Classification of Members of the Group.
	If a group has filed this schedule pursuant to §240.13d-1(b)(1)(ii)(K), so indicate under Item 3(k) and attach an exhibit stating the identity and Item 3 classification of each member of the group. If a group has filed this schedule pursuant to §240.13d-1(c) or §240.13d-1(d), attach an exhibit stating the identity of each member of the group. NOT APPLICABLE
Item 9.	Notice of Dissolution of Group.
	Notice of dissolution of a group may be furnished as an exhibit stating the date of the dissolution and that all further filings with respect to transactions in the security reported on will be filed, if required, by members of the group, in their individual capacity. See Item 5. NOT APPLICABLE

Item 10.

Certifications:

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

STATE STREET CORPORATION

Signature:	ELIZABETH SCHAEFER
Name/Title:	SENIOR VICE PRESIDENT, CHIEF ACCOUNTING OFFICER
Date:	05/12/2026