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Arrowhead Pharma SEC Filings

ARWR NASDAQ

Welcome to our dedicated page for Arrowhead Pharma SEC filings (Ticker: ARWR), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.

When a single RNAi therapy can pivot on a line item buried deep in the footnotes, Arrowhead Pharmaceuticals’ SEC documents often feel like a molecular biology textbook. R&D expenses for the TRIM™ delivery platform, milestone payments from licensing partners, and trial safety data are scattered across hundreds of pages. If you have ever asked, “How do I find Arrowhead Pharmaceuticals insider trading Form 4 transactions?” you already know the challenge.

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Rhea-AI Summary

Local Bounti Corporation (LOCL) has filed a Form 144 disclosing a planned disposition of restricted stock under Rule 144 of the Securities Act.

Seller: KEBS Trust
Planned sale: 3,500 common shares
Broker: Morgan Stanley Smith Barney, New York
Approximate sale date: 10 July 2025 (on the NYSE)
Aggregate market value: $9,261.35
Shares outstanding: 10,914,704
This transaction equals roughly 0.03 % of the company’s outstanding stock, indicating minimal dilution risk.

The shares were originally received as a gift from an affiliate on 28 December 2022. KEBS Trust has already executed several open-market sales in the past three months:

  • 09 Jul 2025 – 200 shares – $602.00
  • 22 May 2025 – 1,179 shares – $2,458.33
  • 21 May 2025 – 600 shares – $1,262.52
  • 20 May 2025 – 800 shares – $1,736.72
  • 19 May 2025 – 1,000 shares – $2,226.60
  • 16 May 2025 – 1,421 shares – $3,326.13

Total prior 3-month sales: 5,200 shares for gross proceeds of about $11,612. The signatory affirms no undisclosed adverse information and acknowledges SEC anti-fraud provisions.

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FAQ

What is the current stock price of Arrowhead Pharma (ARWR)?

The current stock price of Arrowhead Pharma (ARWR) is $18.61 as of July 14, 2025.

What is the market cap of Arrowhead Pharma (ARWR)?

The market cap of Arrowhead Pharma (ARWR) is approximately 2.3B.

What is the primary focus of Arrowhead Pharmaceuticals?

Arrowhead Pharmaceuticals focuses on developing RNA interference (RNAi) therapies to target and silence genes that lead to genetic diseases. Their approach utilizes advanced RNA chemistries to achieve precise, tissue-specific gene knockdown.

How does the TRIM™ platform contribute to the company’s approach?

The TRIM™ platform leverages ligand-mediated delivery to achieve targeted, tissue-specific gene knockdown. Its structural simplicity facilitates streamlined manufacturing and contributes to more precise and efficient therapeutic interventions.

Which therapeutic areas does Arrowhead address?

The company's therapeutic pipeline targets diseases such as hepatitis B, Alpha-1 Antitrypsin Deficiency, thrombosis, angioedema, certain cancers, and cardiovascular disorders. Their strategy centers on conditions where genetic overexpression plays a key role.

What differentiates Arrowhead Pharmaceuticals from other biotechnology companies?

Arrowhead differentiates itself through its deep expertise in RNA interference and its innovative, targeted drug delivery systems. Its focus on gene silencing at the molecular level, backed by the TRIM™ platform, sets it apart in the competitive biotech landscape.

How does RNA interference (RNAi) work in Arrowhead’s therapies?

RNA interference is a natural cellular process that inhibits the expression of specific genes by decreasing protein production. Arrowhead's therapies harness this mechanism to effectively silence disease-causing genes, thereby offering a targeted approach to treatment.

What challenges might Arrowhead Pharmaceuticals face in its market segment?

Challenges include the inherent complexities of clinical development, ensuring efficient and safe delivery of RNAi molecules, and navigating a competitive landscape with other advanced therapeutic modalities. The company’s focus on targeted delivery helps address some of these challenges.

How does the company generate revenue without relying on traditional sales?

Revenue is primarily generated through partnerships, licensing agreements, and milestones achieved during clinical development. As a clinical-stage entity, the focus remains on advancing their pipeline rather than traditional product sales.

How does Arrowhead ensure the precision of its gene silencing technology?

Arrowhead employs advanced RNA chemistries along with the TRIM™ platform for tissue-specific delivery, ensuring that RNAi molecules reach their intended targets. This approach minimizes off-target effects and enhances the overall efficacy of the therapeutic interventions.
Arrowhead Pharma

NASDAQ:ARWR

ARWR Rankings

ARWR Stock Data

2.33B
120.11M
13.2%
74.66%
6.7%
Biotechnology
Pharmaceutical Preparations
Link
United States
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