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Arrowhead Pharma Financials

ARWR
Trailing 12 months to June 30, 2026
Revenue $669.5M YoY not available
Net Income -$320.0M YoY not available
EPS (Diluted) -$2.25 -77.2% YoY
Free Cash Flow -$75.1M -326.3% YoY
Source SEC Filings (10-K/10-Q) Latest period Q3 FY2026, ended Jun 30, 2026 Reported Currency USD FYE September

Arrowhead Pharma (ARWR) reported $669.5M in revenue over the twelve months to Jun 30, 2026. This page shows its income statement, balance sheet, cash flow statement, and key financial ratios. View 15 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Rhea AI ARWR FY2025

Commercial revenue inflection converted heavy research spending into operating profit, while financing costs still kept reported earnings near break-even.

FY2025 paired $179.6M of operating cash flow with $98.3M of operating income and $156.9M of free cash flow, indicating that accounting profitability was accompanied by cash generation rather than funded solely through financing. The cash conversion was also relatively capital-light: capital expenditures consumed only 12.6% of operating cash flow, leaving most internally generated cash available for other uses.

The business shifted from operating losses of $205.0M in FY2023 to operating income of $98.3M in FY2025 as revenue reached $829.4M; that combination points to a major change in commercial scale or revenue mix, not merely incremental cost trimming. Research and development still absorbed 73.2% of FY2025 revenue, so the operating improvement occurred while investment remained substantial.

Net income was a loss of only $1.6M despite positive operating income because interest expense was $89.4M; financing structure therefore obscured the underlying operating result. Total liabilities were $919.2M against $466.1M of equity, while a 4.9x current ratio indicates ample short-term asset coverage even though leverage remains meaningful.

[ NOT FINANCIAL ADVICE ]

Financial Health Signals

Cash Runway Dilution R&DIntensity Revenue Progress BurnTrend BalanceSheet 79 / 100
Financial Health Score 79/100
Scored as: Emerging companies peer group

Scored against emerging companies for FY2025. Each of the six dimensions is a percentile rank within that peer group; the overall is their average, with missing dimensions counted as zero out of six. A high score means strong standing among peers, not absolute cross-industry strength. How this score is calculated →

Health score ≠ stock price. This rates the quality of Arrowhead Pharma's business: profitability, growth, balance sheet strength. It doesn't tell you whether the stock is a good buy at today's price. Not financial advice. Use it alongside valuation analysis and your own research.

Cash Runway
85
Dilution
41
R&D Intensity
99
Revenue Progress
91
Burn Trend
95
Balance Sheet
60
Altman Z-Score Safe
7.47

Arrowhead Pharma scores 7.47, well above the 2.99 safe threshold. The score is driven primarily by a large market capitalization ($11.7B) relative to total liabilities ($919.2M). This indicates low bankruptcy risk based on profitability, leverage, and asset efficiency.

Distress-screening estimate for non-financial companies. Not computed for banks or insurers, where the Altman model does not apply.

Piotroski F-Score Partial
4/7

Arrowhead Pharma passes 4 of 7 computable financial strength tests (2 of the nine could not be computed from available data). 3 of 4 profitability signals pass, no leverage/liquidity signals pass (rising debt, declining liquidity, or share dilution), both operating efficiency signals pass.

Earnings Quality Mixed
N/A

Arrowhead Pharma reported a net loss of $1.6M while generating $179.6M in operating cash flow. Operations generated cash despite the loss, but with no positive earnings behind it, the ratio between the two carries no quality signal.

Interest Coverage At Risk
1.10x

Arrowhead Pharma earns $1.10 in operating income for every $1 of interest expense ($98.3M vs $89.4M). This narrow margin raises concern about the company's ability to service its debt if operating income declines.

Key Financial Metrics

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Earnings & Revenue

Revenue
$829.4M
YoY+23258.2%
5Y CAGR+56.6%
10Y CAGR+115.6%

Arrowhead Pharma generated $829.4M in revenue in fiscal year 2025. This represents an increase of 23258.2% from the prior year.

EBITDA
$120.5M
YoY+120.6%

Arrowhead Pharma's EBITDA was $120.5M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents an increase of 120.6% from the prior year.

Net Income
-$1.6M
YoY+99.7%

Arrowhead Pharma reported -$1.6M in net income in fiscal year 2025. This represents an increase of 99.7% from the prior year.

EPS (Diluted)
-$0.01
YoY+99.8%

Arrowhead Pharma earned -$0.01 per diluted share (EPS) in fiscal year 2025. This represents an increase of 99.8% from the prior year.

Cash & Balance Sheet

Free Cash Flow
$156.9M
YoY+126.0%

Arrowhead Pharma generated $156.9M in free cash flow in fiscal year 2025, representing cash available after capex. This represents an increase of 126.0% from the prior year.

Cash & Debt
$226.5M
YoY+120.6%
5Y CAGR+9.5%
10Y CAGR+10.8%

Arrowhead Pharma held $226.5M in cash as of fiscal year 2025; long-term debt is not reported for that period.

Shares Outstanding
136M
YoY+9.1%
5Y CAGR+5.7%
10Y CAGR+8.6%

Arrowhead Pharma had 136M shares outstanding in fiscal year 2025. This represents an increase of 9.1% from the prior year.

Dividends Per Share

Not reported for fiscal year 2025.

Margins & Returns

Operating Margin
11.9%

Arrowhead Pharma's operating margin was 11.9% in fiscal year 2025, reflecting core business profitability. No change is given against fiscal year 2024: its reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Net Margin
-0.2%
5Y CAGR+95.9pp

Arrowhead Pharma's net profit margin was -0.2% in fiscal year 2025, showing the share of revenue converted to profit. No change is given against fiscal year 2024: its reported ratio is below -100.0% of revenue, so it does not read as a share of revenue.

Return on Equity
-0.4%
YoY+322.9pp
5Y CAGR+18.0pp
10Y CAGR+83.1pp

Arrowhead Pharma's ROE was -0.4% in fiscal year 2025, measuring profit generated per dollar of shareholder equity. This is up 322.9 percentage points from the prior year.

Gross Margin

Not reported for fiscal year 2025.

Capital Allocation

R&D Spending
$607.2M
YoY+20.0%
5Y CAGR+36.3%
10Y CAGR+29.1%

Arrowhead Pharma invested $607.2M in research and development in fiscal year 2025. This represents an increase of 20.0% from the prior year.

Capital Expenditures
$22.7M
YoY-84.0%
5Y CAGR+13.7%
10Y CAGR+27.7%

Arrowhead Pharma invested $22.7M in capex in fiscal year 2025, funding long-term assets and infrastructure. This represents a decrease of 84.0% from the prior year.

Share Buybacks

Not reported for fiscal year 2025.

ARWR Income Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

ARWR quarterly income statement
MetricQ3'26Q2'26Q1'26Q4'25Q3'25Q2'25Q1'25Q4'24
Revenue$75.3M+2.1%$73.7M-72.1%$264.0M+2.9%$256.5M+823.7%$27.8M-94.9%$542.7M+21608.4%$2.5MN/A
R&D Expenses$198.2M+14.4%$173.3M-2.2%$177.2M+1.4%$174.7M+7.6%$162.4M+22.0%$133.1M-2.8%$137.0MN/A
SG&A Expenses$47.1M+12.9%$41.7M-9.3%$46.0M+22.1%$37.7M+21.7%$30.9M+9.0%$28.4M+5.6%$26.9MN/A
Operating Income-$170.1M-20.4%-$141.3M-446.1%$40.8M-7.5%$44.1M+126.6%-$165.6M-143.4%$381.2M+336.2%-$161.4MN/A
Interest Expense$24.6M+3.0%$23.8M+6.0%$22.5M+3.7%$21.7M-11.0%$24.4M+12.7%$21.6M0.0%$21.6MN/A
Income Tax$11K+57.1%$7K-75.9%$29K-99.9%$20.0M+4676.7%-$437K-124.9%$1.8M+1601.9%$103KN/A
Net Income-$194.3M-46.4%-$132.7M-530.8%$30.8M+229.7%-$23.8M+86.4%-$175.2M-147.3%$370.4M+314.0%-$173.1MN/A
EPS (Diluted)-$1.36-46.2%-$0.93-522.7%$0.22+222.2%-$0.18+85.7%-$1.26-145.8%$2.75+297.8%-$1.39-1.5%-$1.37

Not reported in any period shown, so not listed: Cost of Revenue, Gross Profit.

ARWR Balance Sheet

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

ARWR quarterly balance sheet
MetricQ3'26Q2'26Q1'26Q4'25Q3'25Q2'25Q1'25Q4'24
Total Assets$2.1B-6.9%$2.3B+41.4%$1.6B+15.8%$1.4B+0.3%$1.4B-12.3%$1.6B+55.2%$1.0B-11.1%$1.1B
Current Assets$1.7B-9.2%$1.8B+56.7%$1.2B+23.5%$950.6M+0.4%$946.9M-16.6%$1.1B+99.0%$570.5M-18.0%$695.5M
Cash & Equivalents$54.8M-71.0%$188.5M-6.5%$201.6M-11.0%$226.5M+74.5%$129.8M-30.1%$185.7M+244.6%$53.9M-47.5%$102.7M
Accounts Receivable$8.6M-45.5%$15.7M-92.8%$218.9M+3107.4%$6.8M-29.6%$9.7M+310.1%$2.4M-5.4%$2.5M$0
Total Liabilities$1.6B-0.5%$1.7B+59.7%$1.0B+12.7%$919.2M+7.1%$858.3M-3.6%$890.2M-7.4%$961.1M+0.7%$954.4M
Current Liabilities$283.3M-4.0%$295.2M-15.0%$347.4M+77.7%$195.5M+0.5%$194.5M-11.8%$220.5M+135.2%$93.8M-9.1%$103.2M
Total Equity$465.5M-24.2%$614.0M+8.0%$568.4M+22.0%$466.1M-10.8%$522.3M-23.6%$683.3M+1199.4%$52.6M-71.6%$185.4M
Retained Earnings-$1.9B-11.2%-$1.7B-8.3%-$1.6B+1.9%-$1.6B-1.5%-$1.6B-12.3%-$1.4B+20.6%-$1.8B-10.6%-$1.6B

Not reported in any period shown, so not listed: Inventory, Goodwill, Long-Term Debt.

ARWR Cash Flow Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

ARWR quarterly cash flow statement
MetricQ3'26Q2'26Q1'26Q4'25Q3'25Q2'25Q1'25Q4'24
Operating Cash Flow-$177.5M-310.2%$84.4M+526.4%$13.5M-34.2%$20.5M+113.2%-$154.7M-133.6%$460.1M+414.5%-$146.3M-6.6%-$137.2M
Capital Expenditures$3.9M+50.3%$2.6M+19.4%$2.1M-71.3%$7.5M+216.8%$2.4M-55.4%$5.3M-29.5%$7.5M-69.1%$24.3M
Free Cash Flow-$181.3M-321.5%$81.9M+622.5%$11.3M-12.8%$13.0M+108.3%-$157.1M-134.5%$454.8M+395.7%-$153.8M+4.8%-$161.5M
Investing Cash Flow$43.7M+104.9%-$894.3M-3666.7%-$23.7M-132.7%$72.6M-48.6%$141.4M+133.6%-$420.2M-646.4%$76.9M+134.5%-$222.9M
Financing Cash Flow-$449K-100.1%$795.7M+5494.7%-$14.8M-502.0%$3.7M+108.6%-$42.7M-146.2%$92.4M+347.7%$20.6M-94.7%$389.1M

Not reported in any period shown, so not listed: Dividends Paid, Share Buybacks.

ARWR Financial Ratios

Margins and returns are percentages; the remaining ratios are unitless multiples.

ARWR quarterly financial ratios
MetricQ3'26Q2'26Q1'26Q4'25Q3'25Q2'25Q1'25Q4'24
Operating Margin-226.0%-191.6%15.5%-1.7pp17.2%-596.2%70.2%-6456.5%N/A
Net Margin-258.2%-180.0%11.7%+20.9pp-9.3%-631.1%68.3%-6923.4%N/A
Return on Equity-41.7%-20.1pp-21.6%-27.0pp5.4%+10.5pp-5.1%+28.5pp-33.6%-87.8pp54.2%+383.3pp-329.1%N/A
Return on Assets-9.2%-3.3pp-5.9%-7.8pp1.9%+3.6pp-1.7%+11.0pp-12.7%-36.2pp23.5%+40.6pp-17.1%N/A
Current Ratio5.90-0.3x6.23+2.9x3.38-1.5x4.860.0x4.87-0.3x5.15-0.9x6.09-0.7x6.74
Debt-to-Equity3.54+0.8x2.69+0.9x1.82-0.2x1.97+0.3x1.64+0.3x1.30-17.0x18.28+13.1x5.15
FCF Margin-240.9%111.0%4.3%-0.8pp5.1%-565.7%83.8%-6151.5%N/A

Not reported in any period shown, so not listed: Gross Margin.

Reported as filed but not readable as a share of revenue in the periods where the ratio runs further from zero than a revenue base allows; no change figure is given where either compared period is one of those: Operating Margin, Net Margin, FCF Margin.

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Frequently Asked Questions

What is Arrowhead Pharma's annual revenue?

Arrowhead Pharma (ARWR) reported $829.4M in total revenue for fiscal year 2025. This represents a 23258.2% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

How fast is Arrowhead Pharma's revenue growing?

Arrowhead Pharma (ARWR) revenue grew by 23258.2% year-over-year, from $3.6M to $829.4M in fiscal year 2025.

Is Arrowhead Pharma profitable?

No, Arrowhead Pharma (ARWR) reported a net income of -$1.6M in fiscal year 2025, with a net profit margin of -0.2%.

Arrowhead Pharma (ARWR) reported diluted earnings per share of -$0.01 for fiscal year 2025. This represents a 99.8% change compared to the previous fiscal year. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Arrowhead Pharma (ARWR) had EBITDA of $120.5M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

Arrowhead Pharma (ARWR) had an operating margin of 11.9% in fiscal year 2025, reflecting the profitability of core business operations before interest and taxes.

Arrowhead Pharma (ARWR) had a net profit margin of -0.2% in fiscal year 2025, representing the share of revenue converted into profit after all expenses.

Arrowhead Pharma (ARWR) has a return on equity of -0.4% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

Arrowhead Pharma (ARWR) generated $156.9M in free cash flow during fiscal year 2025. This represents a 126.0% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

Arrowhead Pharma (ARWR) generated $179.6M in operating cash flow during fiscal year 2025, representing cash generated from core business activities.

Arrowhead Pharma (ARWR) had $1.4B in total assets as of fiscal year 2025, including both current and long-term assets.

Arrowhead Pharma (ARWR) invested $22.7M in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

Arrowhead Pharma (ARWR) invested $607.2M in research and development during fiscal year 2025.

Arrowhead Pharma (ARWR) had 136M shares outstanding as of fiscal year 2025.

Arrowhead Pharma (ARWR) had a current ratio of 4.86 as of fiscal year 2025, which is generally considered healthy.

Arrowhead Pharma (ARWR) had a debt-to-equity ratio of 1.97 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

Arrowhead Pharma (ARWR) had a return on assets of -0.1% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

Arrowhead Pharma (ARWR) has an Altman Z-Score of 7.47, placing it in the Safe Zone (low bankruptcy risk). The Z-Score combines five financial ratios (working capital, retained earnings, EBIT, market capitalization, and revenue relative to total assets) to predict the likelihood of bankruptcy. Scores above 2.99 indicate financial safety while scores below 1.81 suggest financial distress. Learn more in our complete guide to financial health indicators.

Arrowhead Pharma (ARWR) has a Piotroski F-Score of 4 out of 7 computable signals; 2 of the nine could not be computed from available data, so the full-scale strength rating is not shown. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Arrowhead Pharma (ARWR) reported a net loss of $1.6M while generating $179.6M in operating cash flow. Operations generated cash despite the loss, but with no positive earnings behind it, the ratio between the two carries no quality signal. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

Arrowhead Pharma (ARWR) has an interest coverage ratio of 1.10x, meaning it can struggle to cover its interest obligations. This ratio divides operating income by interest expense. Ratios above 5x indicate strong debt-servicing ability, while ratios below 2x suggest the company may face difficulty meeting interest payments if earnings decline. Learn more in our complete guide to financial health indicators.

Arrowhead Pharma (ARWR) scores 79 out of 100 on our Financial Health Score, indicating strong standing within its emerging companies peer group. The score is a 0-100 composite of six dimensions (Cash Runway, Dilution, R&D Intensity, Revenue Progress, Burn Trend, Balance Sheet), each ranked as a percentile relative to companies in the same scoring family (banks against banks, REITs against REITs, and so on) rather than across all industries. It rates the quality of the business, not whether the stock is fairly priced, and is not financial advice. Learn more in our complete guide to financial health indicators.

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