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Krystal Biotech, Inc. (KRYS) Financials

KRYS
Trailing 12 months to June 30, 2026
Revenue $440.5M +22.6% YoY
Net Income $241.5M +64.6% YoY
EPS (Diluted) $7.98 +61.9% YoY
Free Cash Flow $257.8M +39.0% YoY
Market Cap $9.5B as of Oct 14, 2026
Price / Sales 21.6x on $440.5M revenue, trailing 12 months to June 30, 2026
Price / Earnings 39.4x on $241.5M net income, trailing 12 months to June 30, 2026
Price / Book 7.0x on $1.4B equity, Q2 FY2026

A multiple compares the market's price with a filed figure; it says what the market pays, not how the business is doing. The market capitalization is the vendor's as of Oct 14, 2026; every other figure is from the SEC filings on this page. Not financial advice.

Source SEC Filings (10-K/10-Q) Latest period Q2 FY2026, ended Jun 30, 2026 Reported Currency USD FYE December

Newest figures come from the 10-Q for Q2 FY2026, filed Aug 3, 2026. Each column of the statement tables below links to the filing it was taken from, and every filing is listed on the KRYS SEC filings page.

Krystal Biotech, Inc. (KRYS) reported $440.5M in revenue over the twelve months to Jun 30, 2026, up 22.6% from the prior twelve months. This page shows its income statement, balance sheet, cash flow statement, and key financial ratios. View 10 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Rhea AI KRYS FY2025

Krystal has moved from development spending to a cash-generating commercial model, with operating profitability expanding faster than sales.

In FY2025, operating cash flow of $201M nearly matched net income of $205M, indicating that reported earnings were converting into cash rather than relying mainly on accounting accruals. Free cash flow reached $189M after only $12M of capital spending, revealing a business that currently requires modest reinvestment to support its cash generation.

Revenue expanded from $51M in FY2023 to $389M in FY2025 as the business entered commercial scale. Operating margin widened from 22.6% in FY2024 to 41.5% in FY2025, suggesting fixed operating costs were absorbed as sales scaled rather than growth simply reflecting higher volume.

By FY2025, liabilities of $114M stood against assets of $1.33B, leaving the company largely equity-funded. Debt-to-equity was just 0.1x and the current ratio was 10.0x, so expansion has not required a heavily borrowed balance sheet.

[ NOT FINANCIAL ADVICE ]

Financial Health Signals

Profitability Growth Leverage Liquidity CashFlow Returns 59 / 100
Financial Health Score 59/100

Scored against operating companies for FY2025. Each of the six dimensions is a percentile rank within that peer group; the overall is their average, with missing dimensions counted as zero out of six. A high score means strong standing among peers, not absolute cross-industry strength. How this score is calculated →

Health score ≠ stock price. This rates the quality of Krystal Biotech, Inc.'s business: profitability, growth, balance sheet strength. It doesn't tell you whether the stock is a good buy at today's price. Not financial advice. Use it alongside valuation analysis and your own research.

Profitability
14

Krystal Biotech, Inc. has an operating margin of 41.4%, meaning the company retains $41 of operating profit per $100 of revenue. This below-average margin results in a low score of 14/100, suggesting thin profitability after operating expenses. This is up from 22.6% the prior year.

Growth
99

Krystal Biotech, Inc.'s revenue surged 33.9% year-over-year to $389.1M, reflecting rapid business expansion. This strong growth earns a score of 99/100.

Leverage
81

Krystal Biotech, Inc. carries a low D/E ratio of 0.09, meaning only $0.09 of long-term debt for every $1 of shareholders' equity. This conservative leverage earns a score of 81/100, indicating a strong balance sheet with room for future borrowing.

Liquidity
98

With a current ratio of 9.95, Krystal Biotech, Inc. holds $9.95 in current assets for every $1 of short-term obligations. This comfortable liquidity earns a score of 98/100.

Cash Flow
19

Krystal Biotech, Inc.'s free cash flow margin of 48.5% results in a low score of 19/100. Capital expenditures of $12.0M absorb a large share of operating cash flow.

Returns
40

Krystal Biotech, Inc.'s ROE of 16.8% shows moderate profitability relative to equity, earning a score of 40/100. This is up from 9.4% the prior year.

Altman Z-Score Safe
51.47

Krystal Biotech, Inc. scores 51.47, well above the 2.99 safe threshold. The score is driven primarily by a large market capitalization ($9.5B) relative to total liabilities ($114.2M). This indicates low bankruptcy risk based on profitability, leverage, and asset efficiency.

Distress-screening estimate for non-financial companies. Not computed for banks or insurers, where the Altman model does not apply.

Piotroski F-Score Partial
5/7

Krystal Biotech, Inc. passes 5 of 7 computable financial strength tests (2 of the nine could not be computed from available data). 3 of 4 profitability signals pass, 1 of 2 leverage/liquidity signals pass, both operating efficiency signals pass.

Earnings Quality Mixed
0.98x

For every $1 of reported earnings, Krystal Biotech, Inc. generates $0.98 in operating cash flow ($200.9M OCF vs $204.8M net income). This mixed ratio suggests some earnings may rely on non-cash accounting items.

Key Financial Metrics

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Earnings & Revenue

Revenue
$119.2M
YoY+24.1%
QoQ+2.5%

Krystal Biotech, Inc. generated $119.2M in revenue in Q2 2026. This represents an increase of 24.1% from the same quarter a year earlier. Against the prior quarter it is up 2.5%.

EBITDA
$59.8M
YoY+47.0%
QoQ+8.3%

Krystal Biotech, Inc.'s EBITDA was $59.8M in Q2 2026, measuring earnings before interest, taxes, depreciation, and amortization. This represents an increase of 47.0% from the same quarter a year earlier. Against the prior quarter it is up 8.3%.

Net Income
$54.8M
YoY+42.9%
QoQ-2.1%

Krystal Biotech, Inc. reported $54.8M in net income in Q2 2026. This represents an increase of 42.9% from the same quarter a year earlier. Against the prior quarter it is down 2.1%.

EPS (Diluted)
$1.79
YoY+38.8%
QoQ-2.2%

Krystal Biotech, Inc. earned $1.79 per diluted share (EPS) in Q2 2026. This represents an increase of 38.8% from the same quarter a year earlier. Against the prior quarter it is down 2.2%.

Cash & Balance Sheet

Free Cash Flow
$71.2M
YoY+40.1%
QoQ-2.7%

Krystal Biotech, Inc. generated $71.2M in free cash flow in Q2 2026, representing cash available after capex. This represents an increase of 40.1% from the same quarter a year earlier. Against the prior quarter it is down 2.7%.

Cash & Debt
$427.7M
YoY+20.9%
QoQ-14.7%
5Y CAGR+5.4%

Krystal Biotech, Inc. held $427.7M in cash as of Q2 2026; long-term debt is not reported for that period.

Shares Outstanding
30M
YoY+2.3%
QoQ+0.4%
5Y CAGR+5.9%

Krystal Biotech, Inc. had 30M shares outstanding in Q2 2026. This represents an increase of 2.3% from the same quarter a year earlier. Against the prior quarter it is up 0.4%.

Dividends Per Share

Not reported for Q2 2026.

Margins & Returns

Operating Margin
49.0%
YoY+8.0pp
QoQ+2.9pp

Krystal Biotech, Inc.'s operating margin was 49.0% in Q2 2026, reflecting core business profitability. This is up 8.0 percentage points from the same quarter a year earlier. Against the prior quarter it is up 2.9 percentage points.

Net Margin
45.9%
YoY+6.0pp
QoQ-2.1pp

Krystal Biotech, Inc.'s net profit margin was 45.9% in Q2 2026, showing the share of revenue converted to profit. This is up 6.0 percentage points from the same quarter a year earlier. Against the prior quarter it is down 2.1 percentage points.

Return on Equity
4.0%
YoY+0.4pp
QoQ-0.3pp

Krystal Biotech, Inc.'s ROE was 4.0% in Q2 2026, measuring profit generated per dollar of shareholder equity. This is up 0.4 percentage points from the same quarter a year earlier. Against the prior quarter it is down 0.3 percentage points.

Gross Margin

Not reported for Q2 2026.

Capital Allocation

R&D Spending
$14.5M
YoY+0.7%
QoQ-5.3%

Krystal Biotech, Inc. invested $14.5M in research and development in Q2 2026. This represents an increase of 0.7% from the same quarter a year earlier. Against the prior quarter it is down 5.3%.

Capital Expenditures
$3.6M
YoY+87.2%
QoQ-50.1%
5Y CAGR-2.2%

Krystal Biotech, Inc. invested $3.6M in capex in Q2 2026, funding long-term assets and infrastructure. This represents an increase of 87.2% from the same quarter a year earlier. Against the prior quarter it is down 50.1%.

Share Buybacks

Not reported for Q2 2026.

KRYS Income Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

KRYS quarterly income statement
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-Q
Revenue$119.2M+24.1%$116.4M+31.9%$107.1M+17.5%$97.8M+16.6%$96.0M+36.6%$88.2M+94.9%$91.1M$83.8M+879.9%
R&D Expenses$14.5M+0.7%$15.3M+7.5%$14.8M+9.4%$14.6M+7.9%$14.4M-7.5%$14.3M+30.1%$13.5M$13.5M+27.1%
SG&A Expenses$39.9M+13.6%$41.0M+25.6%$41.4M+32.6%$37.6M+31.1%$35.1M+26.9%$32.6M+25.3%$31.3M$28.7M+21.0%
Operating Income$58.4M+48.3%$53.7M+48.1%$44.3M+6.9%$41.4M+84.1%$39.4M+359.9%$36.3M+642.4%$41.4M$22.5M+186.5%
EBITDA$59.8M+47.0%$55.2M+46.6%$45.9M+7.1%$42.8M+79.9%$40.7M+292.6%$37.7M+816.4%$42.8M$23.8M+195.9%
Income Tax$11.3M+34.0%$5.5M-29.9%-$268K-108.6%-$31.4M-1312.7%$8.4M+1669.8%$7.9M$3.1M$2.6M
Net Income$54.8M+42.9%$55.9M+56.5%$51.4M+13.0%$79.4M+192.0%$38.3M+146.2%$35.7M+3734.0%$45.5M$27.2M-66.3%
EPS (Basic)$1.85+39.1%$1.91+54.0%$1.77+11.3%$2.74+188.4%$1.33+146.3%$1.24+4033.3%$1.59+396.9%$0.95-67.0%
EPS (Diluted)$1.79+38.8%$1.83+52.5%$1.70+11.1%$2.66+192.3%$1.29+143.4%$1.20+3900.0%$1.53+393.5%$0.91-67.4%
Diluted Shares (Avg)31M+3.1%31M+2.1%N/A30M-0.2%30M+0.4%30M+2.0%N/A30M+3.5%

Not reported in any period shown, so not listed: Cost of Revenue, Gross Profit, Interest Expense.

KRYS Balance Sheet

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

KRYS quarterly balance sheet
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-Q
Total Assets$1.5B+31.8%$1.4B+30.0%$1.3B+26.3%$1.2B+26.2%$1.1B+24.1%$1.1B+25.9%$1.1B+29.0%$982.3M+24.3%
Current Assets$1.1B+25.9%$1.0B+33.0%$1.0B+38.1%$925.6M+29.8%$841.3M+23.2%$766.8M+27.3%$742.0M+26.2%$713.2M+22.5%
Cash & Equivalents$427.7M+20.9%$501.3M+62.4%$496.3M+43.9%$392.6M+5.0%$353.8M+2.3%$308.8M-14.0%$344.9M-3.8%$374.0M+0.2%
Short-Term Investments$417.9M+27.3%$322.1M+4.5%$331.5M+31.2%$338.5M+57.9%$328.2M+53.5%$308.1M+71.9%$252.7M+45.3%$214.4M+13.5%
Inventory$45.6M+46.8%$42.6M+42.4%$40.5M+52.7%$37.6M+102.5%$31.0M+154.9%$29.9M+171.3%$26.5M+279.5%$18.6M+252.0%
Accounts Receivable$138.7M+24.4%$127.0M+23.0%$127.4M+21.7%$129.6M+33.2%$111.4M+7.9%$103.3M-1.4%$104.7M+149.2%$97.3M+944.4%
Long-Term Investments$257.3M+85.4%$193.5M+30.3%$128.1M-15.8%$133.1M+25.7%$138.8M+100.3%$148.5M+76.8%$152.1M+145.5%$105.9M+189.7%
Total Liabilities$141.5M+44.8%$120.2M+34.0%$114.2M+4.4%$102.2M+6.0%$97.7M+24.1%$89.7M+66.0%$109.5M+175.6%$96.5M+180.4%
Current Liabilities$127.4M+46.6%$107.8M+35.6%$102.9M+0.9%$91.3M+1.9%$86.9M+20.9%$79.5M+67.0%$102.0M+208.2%$89.5M+224.6%
Non-Current Liabilities$14.1M+30.2%$12.4M+21.3%$11.3M+51.3%$10.9M+57.7%$10.9M+56.9%$10.3M+58.6%$7.5M+12.7%$6.9M+1.8%
Total Equity$1.4B+30.6%$1.3B+29.7%$1.2B+28.9%$1.1B+28.5%$1.0B+24.1%$984.7M+23.2%$946.4M+21.5%$885.8M+17.2%
Retained Earnings$134.9M+226.5%$80.1M+155.3%$24.2M+113.4%-$27.2M+88.0%-$106.6M+57.9%-$144.9M+46.1%-$180.7M+33.0%-$226.1M+18.8%

Not reported in any period shown, so not listed: Goodwill, Long-Term Debt.

KRYS Cash Flow Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

KRYS quarterly cash flow statement
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-Q
Operating Cash Flow$74.8M+41.8%$80.4M+159.6%$77.5M+46.7%$39.7M-32.6%$52.7M+1365.1%$31.0M+94.9%$52.8M+830.7%$58.9M+377.3%
Depreciation & Amortization$1.4M+7.7%$1.5M+7.9%$1.6M+14.5%$1.4M+7.7%$1.3M-27.8%$1.4M-1.2%$1.4M-10.5%$1.3M+8.3%
Stock-Based Compensation$14.2M+0.3%$13.6M+1.0%N/AN/A$14.1M$13.5M+44.9%N/AN/A
Capital Expenditures$3.6M+87.2%$7.1M+15.2%$2.1M+167.0%$1.7M+62.9%$1.9M+68.3%$6.2M+392.4%$801K-56.6%$1.0M-41.3%
Free Cash Flow$71.2M+40.1%$73.2M+195.7%$75.4M+44.8%$38.0M-34.3%$50.8M+1059.1%$24.8M+69.3%$52.0M+673.2%$57.8M+351.3%
Investing Cash Flow-$161.6M-1435.2%-$63.6M-16.1%$11.2M+113.3%-$4.3M+87.5%-$10.5M+45.6%-$54.8M-110.8%-$83.8M-724.6%-$34.3M-132.6%
Financing Cash Flow$15.1M+738.1%-$10.5M+16.1%$15.7M+545.2%$3.7M+10.2%$1.8M-83.1%-$12.5M-217.8%$2.4M-7.3%$3.4M-74.9%

Not reported in any period shown, so not listed: Dividends Paid, Share Buybacks.

KRYS Financial Ratios

Margins and returns are percentages; the remaining ratios are unitless multiples. Each change compares the year with the year before it, and each quarter with the same quarter a year earlier.

KRYS quarterly financial ratios
MetricQ2'2610-QQ1'2610-QQ4'2510-QQ3'2510-QQ2'2510-QQ1'2510-QQ4'2410-KQ3'2410-Q
Operating Margin49.0%+8.0pp46.1%+5.0pp41.3%-4.1pp42.3%+15.5pp41.0%+28.8pp41.1%+55.9pp45.4%26.8%
Net Margin45.9%+6.0pp48.1%+7.6pp48.0%-1.9pp81.2%+48.7pp39.9%+17.8pp40.5%+38.5pp49.9%32.4%
Return on Equity4.0%+0.4pp4.4%+0.8pp4.2%-0.6pp7.0%+3.9pp3.7%+1.8pp3.6%+3.5pp4.8%3.1%-7.6pp
Return on Assets3.6%+0.3pp4.0%+0.7pp3.9%-0.5pp6.4%+3.6pp3.4%+1.7pp3.3%+3.2pp4.3%2.8%-7.4pp
Current Ratio8.32-1.4x9.46-0.2x9.95+2.7x10.14+2.2x9.68+0.2x9.65-3.0x7.28-10.5x7.97-13.1x
Debt-to-Equity0.100.0x0.090.0x0.090.0x0.090.0x0.090.0x0.090.0x0.12+0.1x0.11+0.1x
Asset Turnover0.080.0x0.080.0x0.080.0x0.080.0x0.080.0x0.080.0x0.090.09+0.1x
FCF Margin59.7%+6.8pp62.9%+34.9pp70.4%+13.3pp38.8%-30.1pp52.9%+60.5pp28.1%-4.2pp57.1%69.0%

Not reported in any period shown, so not listed: Gross Margin.

Similar Companies

Newest fiscal year on record for each company. The health score is the peer-relative Financial Health Score for that year; a dash means no score is published for it.

Company Fiscal year Revenue Net income Net margin Market cap Health score
Krystal Biotech, Inc. KRYS FY2025 $389.1M $204.8M 52.6% $9.5B 59/100
Arrowhead Research Corporation ARWR FY2025 $829.4M -$1.6M -0.2% $8.2B 78/100
Arcellx, Inc. ACLX FY2025 $22.3M -$228.9M N/A $6.7B 46/100
Acadia Pharmaceuticals Inc. ACAD FY2025 $1.1B $391.0M 36.5% $3.2B 68/100
Metsera, Inc. MTSR FY2024 N/A -$209.1M N/A $7.4B —
Mirum Pharmaceuticals, Inc. MIRM FY2025 $521.3M -$23.4M -4.5% $5.2B 71/100

Frequently Asked Questions

What is Krystal Biotech, Inc.'s annual revenue?

Krystal Biotech, Inc. (KRYS) reported $389.1M in total revenue for fiscal year 2025. This represents a 33.9% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

How fast is Krystal Biotech, Inc.'s revenue growing?

Krystal Biotech, Inc. (KRYS) revenue grew by 33.9% year-over-year, from $290.5M to $389.1M in fiscal year 2025.

Is Krystal Biotech, Inc. profitable?

Yes, Krystal Biotech, Inc. (KRYS) reported a net income of $204.8M in fiscal year 2025, with a net profit margin of 52.6%.

Krystal Biotech, Inc. (KRYS) reported diluted earnings per share of $6.84 for fiscal year 2025. This represents a 128.0% change compared to the previous fiscal year. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Krystal Biotech, Inc. (KRYS) had EBITDA of $167.0M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

Krystal Biotech, Inc. (KRYS) had an operating margin of 41.4% in fiscal year 2025, reflecting the profitability of core business operations before interest and taxes.

Krystal Biotech, Inc. (KRYS) had a net profit margin of 52.6% in fiscal year 2025, representing the share of revenue converted into profit after all expenses.

Krystal Biotech, Inc. (KRYS) has a return on equity of 16.8% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

Krystal Biotech, Inc. (KRYS) generated $188.9M in free cash flow during fiscal year 2025. This represents a 58.5% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

Krystal Biotech, Inc. (KRYS) generated $200.9M in operating cash flow during fiscal year 2025, representing cash generated from core business activities.

Krystal Biotech, Inc. (KRYS) had $1.3B in total assets as of fiscal year 2025, including both current and long-term assets.

Krystal Biotech, Inc. (KRYS) invested $12.0M in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

Krystal Biotech, Inc. (KRYS) invested $58.0M in research and development during fiscal year 2025.

Krystal Biotech, Inc. (KRYS) had 29M shares outstanding as of fiscal year 2025.

Krystal Biotech, Inc. (KRYS) had a current ratio of 9.95 as of fiscal year 2025, which is generally considered healthy.

Krystal Biotech, Inc. (KRYS) had a debt-to-equity ratio of 0.09 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

Krystal Biotech, Inc. (KRYS) had a return on assets of 15.4% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

Krystal Biotech, Inc. (KRYS) trades at 39.4x earnings, its market capitalization divided by net income of $241.5M net income, trailing 12 months to June 30, 2026. The market capitalization is $9.5B as of Oct 14, 2026; a multiple compares that price with a filed figure and says nothing about the quality of the business.

Krystal Biotech, Inc. (KRYS) trades at 21.6x sales, its market capitalization divided by revenue of $440.5M revenue, trailing 12 months to June 30, 2026. The market capitalization is $9.5B as of Oct 14, 2026; a multiple compares that price with a filed figure and says nothing about the quality of the business.

Krystal Biotech, Inc. (KRYS) has an Altman Z-Score of 51.47, placing it in the Safe Zone (low bankruptcy risk). The Z-Score combines five financial ratios (working capital, retained earnings, EBIT, market capitalization, and revenue relative to total assets) to predict the likelihood of bankruptcy. Scores above 2.99 indicate financial safety while scores below 1.81 suggest financial distress. Learn more in our complete guide to financial health indicators.

Krystal Biotech, Inc. (KRYS) has a Piotroski F-Score of 5 out of 7 computable signals; 2 of the nine could not be computed from available data, so the full-scale strength rating is not shown. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Krystal Biotech, Inc. (KRYS) has an earnings quality ratio of 0.98x, considered mixed quality. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

Krystal Biotech, Inc. (KRYS) scores 59 out of 100 on our Financial Health Score, indicating moderate standing within its operating companies peer group. The score is a 0-100 composite of six dimensions (Profitability, Growth, Leverage, Liquidity, Cash Flow, Returns), each ranked as a percentile relative to companies in the same scoring family (banks against banks, REITs against REITs, and so on) rather than across all industries. It rates the quality of the business, not whether the stock is fairly priced, and is not financial advice. Learn more in our complete guide to financial health indicators.

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