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Krystal Biotech Financials

KRYS
Trailing 12 months to June 30, 2026
Revenue $440.5M +22.6% YoY
Net Income $241.5M +64.6% YoY
EPS (Diluted) $7.98 +61.9% YoY
Free Cash Flow $257.8M +39.0% YoY
Source SEC Filings (10-K/10-Q) Latest period Q2 FY2026, ended Jun 30, 2026 Reported Currency USD FYE December

Krystal Biotech (KRYS) reported $440.5M in revenue over the twelve months to Jun 30, 2026, up 22.6% from the prior twelve months. This page shows its income statement, balance sheet, cash flow statement, and key financial ratios. View 10 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Rhea AI KRYS FY2025

Revenue growth is increasingly dropping through to profit and cash while the balance sheet remains lightly leveraged.

The move from an operating margin of -216.2% in FY2023 to 41.5% in FY2025 marks a shift from investment-heavy operations toward profitable scale. In FY2025, $188.9M of free cash flow followed $200.9M of operating cash flow, indicating that only a modest portion of internally generated cash was absorbed by reinvestment.

FY2025 revenue expanded 34.0% from FY2024 while selling, general and administrative expense increased 29.1%. Expense growth lagged revenue growth, helping explain why operating margin widened rather than merely preserving profitability.

Total liabilities barely changed from $109.5M in FY2024 to $114.2M in FY2025 even as assets expanded. The combination of a 9.95x current ratio and 0.1x debt-to-equity indicates expansion financed mainly through equity and internally generated resources rather than rising debt.

[ NOT FINANCIAL ADVICE ]

Financial Health Signals

Profitability Growth Leverage Liquidity CashFlow Returns 60 / 100
Financial Health Score 60/100

Scored against operating companies for FY2025. Each of the six dimensions is a percentile rank within that peer group; the overall is their average, with missing dimensions counted as zero out of six. A high score means strong standing among peers, not absolute cross-industry strength. How this score is calculated →

Health score ≠ stock price. This rates the quality of Krystal Biotech's business: profitability, growth, balance sheet strength. It doesn't tell you whether the stock is a good buy at today's price. Not financial advice. Use it alongside valuation analysis and your own research.

Profitability
18

Krystal Biotech has an operating margin of 41.4%, meaning the company retains $41 of operating profit per $100 of revenue. This below-average margin results in a low score of 18/100, suggesting thin profitability after operating expenses. This is up from 22.6% the prior year.

Growth
99

Krystal Biotech's revenue surged 33.9% year-over-year to $389.1M, reflecting rapid business expansion. This strong growth earns a score of 99/100.

Leverage
81

Krystal Biotech carries a low D/E ratio of 0.09, meaning only $0.09 of long-term debt for every $1 of shareholders' equity. This conservative leverage earns a score of 81/100, indicating a strong balance sheet with room for future borrowing.

Liquidity
97

With a current ratio of 9.95, Krystal Biotech holds $9.95 in current assets for every $1 of short-term obligations. This comfortable liquidity earns a score of 97/100.

Cash Flow
22

Krystal Biotech's free cash flow margin of 48.5% results in a low score of 22/100. Capital expenditures of $12.0M absorb a large share of operating cash flow.

Returns
40

Krystal Biotech's ROE of 16.8% shows moderate profitability relative to equity, earning a score of 40/100. This is up from 9.4% the prior year.

Altman Z-Score Safe
56.18

Krystal Biotech scores 56.18, well above the 2.99 safe threshold. The score is driven primarily by a large market capitalization ($10.4B) relative to total liabilities ($114.2M). This indicates low bankruptcy risk based on profitability, leverage, and asset efficiency.

Distress-screening estimate for non-financial companies. Not computed for banks or insurers, where the Altman model does not apply.

Piotroski F-Score Partial
5/7

Krystal Biotech passes 5 of 7 computable financial strength tests (2 of the nine could not be computed from available data). 3 of 4 profitability signals pass, 1 of 2 leverage/liquidity signals pass, both operating efficiency signals pass.

Earnings Quality Mixed
0.98x

For every $1 of reported earnings, Krystal Biotech generates $0.98 in operating cash flow ($200.9M OCF vs $204.8M net income). This mixed ratio suggests some earnings may rely on non-cash accounting items.

Key Financial Metrics

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Earnings & Revenue

Revenue
$389.1M
YoY+33.9%

Krystal Biotech generated $389.1M in revenue in fiscal year 2025. This represents an increase of 33.9% from the prior year.

EBITDA
$167.0M
YoY+132.9%

Krystal Biotech's EBITDA was $167.0M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents an increase of 132.9% from the prior year.

Net Income
$204.8M
YoY+129.7%

Krystal Biotech reported $204.8M in net income in fiscal year 2025. This represents an increase of 129.7% from the prior year.

EPS (Diluted)
$6.84
YoY+128.0%

Krystal Biotech earned $6.84 per diluted share (EPS) in fiscal year 2025. This represents an increase of 128.0% from the prior year.

Cash & Balance Sheet

Free Cash Flow
$188.9M
YoY+58.5%

Krystal Biotech generated $188.9M in free cash flow in fiscal year 2025, representing cash available after capex. This represents an increase of 58.5% from the prior year.

Cash & Debt
$496.3M
YoY+43.9%
5Y CAGR+13.1%

Krystal Biotech held $496.3M in cash as of fiscal year 2025; long-term debt is not reported for that period.

Shares Outstanding
29M
YoY+1.5%
5Y CAGR+5.7%

Krystal Biotech had 29M shares outstanding in fiscal year 2025. This represents an increase of 1.5% from the prior year.

Dividends Per Share

Not reported for fiscal year 2025.

Margins & Returns

Operating Margin
41.4%
YoY+18.8pp

Krystal Biotech's operating margin was 41.4% in fiscal year 2025, reflecting core business profitability. This is up 18.8 percentage points from the prior year.

Net Margin
52.6%
YoY+21.9pp

Krystal Biotech's net profit margin was 52.6% in fiscal year 2025, showing the share of revenue converted to profit. This is up 21.9 percentage points from the prior year.

Return on Equity
16.8%
YoY+7.4pp
5Y CAGR+27.8pp

Krystal Biotech's ROE was 16.8% in fiscal year 2025, measuring profit generated per dollar of shareholder equity. This is up 7.4 percentage points from the prior year.

Gross Margin

Not reported for fiscal year 2025.

Capital Allocation

R&D Spending
$58.0M
YoY+8.3%
5Y CAGR+26.5%

Krystal Biotech invested $58.0M in research and development in fiscal year 2025. This represents an increase of 8.3% from the prior year.

Capital Expenditures
$12.0M
YoY+182.0%
5Y CAGR-4.2%

Krystal Biotech invested $12.0M in capex in fiscal year 2025, funding long-term assets and infrastructure. This represents an increase of 182.0% from the prior year.

Share Buybacks

Not reported for fiscal year 2025.

KRYS Income Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

KRYS quarterly income statement
MetricQ2'26Q1'26Q4'25Q3'25Q2'25Q1'25Q4'24Q3'24
Revenue$119.2M+2.5%$116.4M+8.6%$107.1M+9.5%$97.8M+1.8%$96.0M+8.9%$88.2M-3.2%$91.1M+8.7%$83.8M
R&D Expenses$14.5M-5.3%$15.3M+3.6%$14.8M+1.4%$14.6M+1.2%$14.4M+1.1%$14.3M+5.4%$13.5M+0.1%$13.5M
SG&A Expenses$39.9M-2.8%$41.0M-1.0%$41.4M+10.3%$37.6M+7.2%$35.1M+7.4%$32.6M+4.4%$31.3M+9.1%$28.7M
Operating Income$58.4M+8.8%$53.7M+21.3%$44.3M+7.0%$41.4M+5.0%$39.4M+8.7%$36.3M-12.4%$41.4M+84.2%$22.5M
Income Tax$11.3M+105.3%$5.5M+2156.0%-$268K+99.1%-$31.4M-471.9%$8.4M+7.3%$7.9M+151.2%$3.1M+20.9%$2.6M
Net Income$54.8M-2.1%$55.9M+8.8%$51.4M-35.2%$79.4M+107.0%$38.3M+7.3%$35.7M-21.4%$45.5M+67.3%$27.2M
EPS (Diluted)$1.79-2.2%$1.83+7.6%$1.70-36.1%$2.66+106.2%$1.29+7.5%$1.20-21.6%$1.53+68.1%$0.91

Not reported in any period shown, so not listed: Cost of Revenue, Gross Profit, Interest Expense.

KRYS Balance Sheet

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

KRYS quarterly balance sheet
MetricQ2'26Q1'26Q4'25Q3'25Q2'25Q1'25Q4'24Q3'24
Total Assets$1.5B+7.4%$1.4B+4.7%$1.3B+7.6%$1.2B+8.9%$1.1B+6.0%$1.1B+1.8%$1.1B+7.5%$982.3M
Current Assets$1.1B+3.9%$1.0B-0.5%$1.0B+10.7%$925.6M+10.0%$841.3M+9.7%$766.8M+3.3%$742.0M+4.0%$713.2M
Cash & Equivalents$427.7M-14.7%$501.3M+1.0%$496.3M+26.4%$392.6M+11.0%$353.8M+14.6%$308.8M-10.5%$344.9M-7.8%$374.0M
Inventory$45.6M+6.8%$42.6M+5.4%$40.5M+7.6%$37.6M+21.2%$31.0M+3.7%$29.9M+13.0%$26.5M+42.7%$18.6M
Accounts Receivable$138.7M+9.2%$127.0M-0.3%$127.4M-1.7%$129.6M+16.3%$111.4M+7.9%$103.3M-1.4%$104.7M+7.7%$97.3M
Total Liabilities$141.5M+17.7%$120.2M+5.3%$114.2M+11.8%$102.2M+4.6%$97.7M+8.9%$89.7M-18.0%$109.5M+13.5%$96.5M
Current Liabilities$127.4M+18.2%$107.8M+4.7%$102.9M+12.8%$91.3M+5.0%$86.9M+9.3%$79.5M-22.1%$102.0M+13.9%$89.5M
Total Equity$1.4B+6.5%$1.3B+4.7%$1.2B+7.2%$1.1B+9.3%$1.0B+5.7%$984.7M+4.0%$946.4M+6.8%$885.8M
Retained Earnings$134.9M+68.4%$80.1M+231.5%$24.2M+188.7%-$27.2M+74.4%-$106.6M+26.4%-$144.9M+19.8%-$180.7M+20.1%-$226.1M

Not reported in any period shown, so not listed: Goodwill, Long-Term Debt.

KRYS Cash Flow Statement

Figures in USD, abbreviated K (thousand), M (million), B (billion), T (trillion). Negative values carry a minus sign and red type.

KRYS quarterly cash flow statement
MetricQ2'26Q1'26Q4'25Q3'25Q2'25Q1'25Q4'24Q3'24
Operating Cash Flow$74.8M-7.0%$80.4M+3.7%$77.5M+95.4%$39.7M-24.8%$52.7M+70.3%$31.0M-41.4%$52.8M-10.2%$58.9M
Capital Expenditures$3.6M-50.1%$7.1M+234.2%$2.1M+25.5%$1.7M-10.5%$1.9M-69.3%$6.2M+674.5%$801K-23.4%$1.0M
Free Cash Flow$71.2M-2.7%$73.2M-2.8%$75.4M+98.6%$38.0M-25.3%$50.8M+105.2%$24.8M-52.4%$52.0M-10.0%$57.8M
Investing Cash Flow-$161.6M-154.1%-$63.6M-669.6%$11.2M+360.5%-$4.3M+59.3%-$10.5M+80.8%-$54.8M+34.6%-$83.8M-144.1%-$34.3M
Financing Cash Flow$15.1M+243.9%-$10.5M-166.8%$15.7M+322.4%$3.7M+106.5%$1.8M+114.4%-$12.5M-613.4%$2.4M-27.8%$3.4M

Not reported in any period shown, so not listed: Dividends Paid, Share Buybacks.

KRYS Financial Ratios

Margins and returns are percentages; the remaining ratios are unitless multiples.

KRYS quarterly financial ratios
MetricQ2'26Q1'26Q4'25Q3'25Q2'25Q1'25Q4'24Q3'24
Operating Margin49.0%+2.9pp46.1%+4.8pp41.3%-1.0pp42.3%+1.3pp41.0%-0.1pp41.1%-4.3pp45.4%+18.6pp26.8%
Net Margin45.9%-2.1pp48.1%+0.1pp48.0%-33.2pp81.2%+41.2pp39.9%-0.6pp40.5%-9.4pp49.9%+17.5pp32.4%
Return on Equity4.0%-0.3pp4.4%+0.2pp4.2%-2.8pp7.0%+3.3pp3.7%+0.1pp3.6%-1.2pp4.8%+1.7pp3.1%
Return on Assets3.6%-0.4pp4.0%+0.2pp3.9%-2.6pp6.4%+3.0pp3.4%0.0pp3.3%-1.0pp4.3%+1.5pp2.8%
Current Ratio8.32-1.1x9.46-0.5x9.95-0.2x10.14+0.5x9.680.0x9.65+2.4x7.28-0.7x7.97
Debt-to-Equity0.100.0x0.090.0x0.090.0x0.090.0x0.090.0x0.090.0x0.120.0x0.11
FCF Margin59.7%-3.2pp62.9%-7.4pp70.4%+31.6pp38.8%-14.1pp52.9%+24.8pp28.1%-29.0pp57.1%-11.9pp69.0%

Not reported in any period shown, so not listed: Gross Margin.

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Frequently Asked Questions

What is Krystal Biotech's annual revenue?

Krystal Biotech (KRYS) reported $389.1M in total revenue for fiscal year 2025. This represents a 33.9% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

How fast is Krystal Biotech's revenue growing?

Krystal Biotech (KRYS) revenue grew by 33.9% year-over-year, from $290.5M to $389.1M in fiscal year 2025.

Is Krystal Biotech profitable?

Yes, Krystal Biotech (KRYS) reported a net income of $204.8M in fiscal year 2025, with a net profit margin of 52.6%.

Krystal Biotech (KRYS) reported diluted earnings per share of $6.84 for fiscal year 2025. This represents a 128.0% change compared to the previous fiscal year. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Krystal Biotech (KRYS) had EBITDA of $167.0M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

Krystal Biotech (KRYS) had an operating margin of 41.4% in fiscal year 2025, reflecting the profitability of core business operations before interest and taxes.

Krystal Biotech (KRYS) had a net profit margin of 52.6% in fiscal year 2025, representing the share of revenue converted into profit after all expenses.

Krystal Biotech (KRYS) has a return on equity of 16.8% for fiscal year 2025, measuring how efficiently the company generates profit from shareholder equity.

Krystal Biotech (KRYS) generated $188.9M in free cash flow during fiscal year 2025. This represents a 58.5% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

Krystal Biotech (KRYS) generated $200.9M in operating cash flow during fiscal year 2025, representing cash generated from core business activities.

Krystal Biotech (KRYS) had $1.3B in total assets as of fiscal year 2025, including both current and long-term assets.

Krystal Biotech (KRYS) invested $12.0M in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

Krystal Biotech (KRYS) invested $58.0M in research and development during fiscal year 2025.

Krystal Biotech (KRYS) had 29M shares outstanding as of fiscal year 2025.

Krystal Biotech (KRYS) had a current ratio of 9.95 as of fiscal year 2025, which is generally considered healthy.

Krystal Biotech (KRYS) had a debt-to-equity ratio of 0.09 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

Krystal Biotech (KRYS) had a return on assets of 15.4% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

Krystal Biotech (KRYS) has an Altman Z-Score of 56.18, placing it in the Safe Zone (low bankruptcy risk). The Z-Score combines five financial ratios (working capital, retained earnings, EBIT, market capitalization, and revenue relative to total assets) to predict the likelihood of bankruptcy. Scores above 2.99 indicate financial safety while scores below 1.81 suggest financial distress. Learn more in our complete guide to financial health indicators.

Krystal Biotech (KRYS) has a Piotroski F-Score of 5 out of 7 computable signals; 2 of the nine could not be computed from available data, so the full-scale strength rating is not shown. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7 to 9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Krystal Biotech (KRYS) has an earnings quality ratio of 0.98x, considered mixed quality. This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

Krystal Biotech (KRYS) scores 60 out of 100 on our Financial Health Score, indicating moderate standing within its operating companies peer group. The score is a 0-100 composite of six dimensions (Profitability, Growth, Leverage, Liquidity, Cash Flow, Returns), each ranked as a percentile relative to companies in the same scoring family (banks against banks, REITs against REITs, and so on) rather than across all industries. It rates the quality of the business, not whether the stock is fairly priced, and is not financial advice. Learn more in our complete guide to financial health indicators.

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