James Hamilton (ARWR) files Rule 144 notice to sell 10,000 shares

Rhea-AI Filing Summary

James Hamilton reported proposed sales of Common Stock under Rule 144. The filing lists an aggregate proposed sale of 10,000 shares and subdivided lots of 5,708, 542, 1,628, and 2,122 dated 01/04/2026. The filing also shows a prior sale of 10,000 shares on 03/05/2026 for $641,870.05.

Insights

Insider Transactions Analyst

Routine Rule 144 sale notice by an insider; amounts and a recent prior sale are disclosed.

The filing lists proposed dispositions of Common Stock in multiple lots dated 01/04/2026 totaling 10,000 shares and shows a sale of 10,000 shares on 03/05/2026 for $641,870.05. The entries are labeled "Compensation," indicating the shares originated from compensation-related grants.

Cashflow treatment or plan details are not included beyond the per-lot labels. Subsequent SEC filings or confirmations would show whether the proposed Rule 144 sales were executed and the ultimate buyer types.

Key Figures

Proposed shares to be sold: 10,000 shares Lot — 5,708 shares: 5,708 shares Lot — 542 shares: 542 shares +5 more

8 metrics

Proposed shares to be sold 10,000 shares aggregate proposed sale (lots dated 01/04/2026)

Lot — 5,708 shares 5,708 shares one compensation lot dated 01/04/2026

Lot — 542 shares 542 shares one compensation lot dated 01/04/2026

Lot — 1,628 shares 1,628 shares one compensation lot dated 01/04/2026

Lot — 2,122 shares 2,122 shares one compensation lot dated 01/04/2026

Sale in past 3 months 10,000 shares sold on 03/05/2026

Aggregate amount reported $641,870.05 amount tied to 03/05/2026 sale of 10,000 shares

Filing date in content 04/23/2026 date shown near securities header

Key Terms

Rule 144, Compensation, Securities Sold During The Past 3 Months

3 terms

Rule 144 regulatory

"144: Securities To Be Sold"

Rule 144 is a U.S. securities regulation that sets conditions under which restricted or insider-held shares can be legally resold to the public, such as required holding periods, availability of public information, limits on how much can be sold at once, and certain filing requirements. For investors it matters because it determines when previously locked-up shares can enter the market — like a release valve that can increase supply, affect share price, and signal insider intent.

Compensation financial

"Common | 01/04/2026 | Compensation | James Hamilton"

Securities Sold During The Past 3 Months regulatory

"144: Securities Sold During The Past 3 Months | James Hamilton"

Form 144 Filer Information	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 144 NOTICE OF PROPOSED SALE OF SECURITIES PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933
FORM 144

144: Filer Information

Filer CIK
Filer CCC
Is this a LIVE or TEST Filing?	LIVE TEST
Submission Contact Information
Name
Phone
E-Mail Address

144: Issuer Information

Name of Issuer

SEC File Number

Address of Issuer

Phone

Name of Person for Whose Account the Securities are To Be Sold

See the definition of "person" in paragraph (a) of Rule 144. Information is to be given not only as to the person for whose account the securities are to be sold but also as to all other persons included in that definition. In addition, information shall be given as to sales by all persons whose sales are required by paragraph (e) of Rule 144 to be aggregated with sales for the account of the person filing this notice.

Relationship to Issuer

144: Securities Information

Title of the Class of Securities To Be Sold	Name and Address of the Broker	Number of Shares or Other Units To Be Sold	Aggregate Market Value	Number of Shares or Other Units Outstanding	Approximate Date of Sale	Name the Securities Exchange
Common	Merrill Lynch 75 Rockefeller Plaza Fl 2 New York NY 10019	10000	749997.6	140032190	04/23/2026	Nasdaq

Furnish the following information with respect to the acquisition of the securities to be sold and with respect to the payment of all or any part of the purchase price or other consideration therefor:

144: Securities To Be Sold

Title of the Class	Date you Acquired	Nature of Acquisition Transaction	Name of Person from Whom Acquired	Is this a Gift?	Date Donor Acquired	Amount of Securities Acquired	Date of Payment	Nature of Payment *
Common	01/04/2026	Compensation	James Hamilton			5708	01/04/2026	Compensation
Common	01/04/2026	Compensation	James Hamilton			542	01/04/2026	Compensation
Common	01/04/2026	Compensation	James Hamilton			1628	01/04/2026	Compensation
Common	01/04/2026	Compensation	James Hamilton			2122	01/04/2026	Compensation

* If the securities were purchased and full payment therefor was not made in cash at the time of purchase, explain in the table or in a note thereto the nature of the consideration given. If the consideration consisted of any note or other obligation, or if payment was made in installments describe the arrangement and state when the note or other obligation was discharged in full or the last installment paid.

Furnish the following information as to all securities of the issuer sold during the past 3 months by the person for whose account the securities are to be sold.

144: Securities Sold During The Past 3 Months

Name and Address of Seller	Title of Securities Sold	Date of Sale	Amount of Securities Sold	Gross Proceeds
James Hamilton 177 E. Colorado Blvd Suite 700 Pasadena CA 91105	Common	03/05/2026	10000	641870.05

144: Remarks and Signature

Remarks

Date of Notice

ATTENTION:

The person for whose account the securities to which this notice relates are to be sold hereby represents by signing this notice that he does not know any material adverse information in regard to the current and prospective operations of the Issuer of the securities to be sold which has not been publicly disclosed. If such person has adopted a written trading plan or given trading instructions to satisfy Rule 10b5-1 under the Exchange Act, by signing the form and indicating the date that the plan was adopted or the instruction given, that person makes such representation as of the plan adoption or instruction date.

Signature

ATTENTION: Intentional misstatements or omission of facts constitute Federal Criminal Violations (See 18 U.S.C. 1001)