BlackRock reports 10.1% stake in Arrowhead

BlackRock, Inc. filed an amended Schedule 13G reporting a significant ownership position in Arrowhead Pharmaceuticals Inc. common stock.

Rhea-AI Filing Summary

BlackRock, Inc. filed an amended Schedule 13G reporting a significant ownership position in Arrowhead Pharmaceuticals Inc. common stock. BlackRock reports beneficial ownership of 14,232,545 shares, representing 10.1% of Arrowhead’s outstanding common stock.

BlackRock has sole voting power over 13,849,022 shares and sole dispositive power over 14,232,545 shares, with no shared voting or dispositive power. Various underlying clients have economic rights to dividends and sale proceeds, but no individual client holds more than five percent of Arrowhead’s outstanding common shares.

Key Figures

Beneficially owned shares: 14,232,545 shares Percent of class: 10.1% Sole voting power: 13,849,022 shares +1 more

4 metrics

Beneficially owned shares 14,232,545 shares Shares of Arrowhead Pharmaceuticals common stock beneficially owned by BlackRock

Percent of class 10.1% Portion of Arrowhead Pharmaceuticals’ outstanding common stock held by BlackRock

Sole voting power 13,849,022 shares Shares for which BlackRock has sole power to vote or direct the vote

Sole dispositive power 14,232,545 shares Shares for which BlackRock has sole power to dispose or direct disposition

Key Terms

beneficially owned, Sole Voting Power, Sole Dispositive Power, Schedule 13G, +1 more

5 terms

beneficially owned financial

"this reflects the securities beneficially owned, or deemed to be beneficially owned"

Beneficially owned describes securities or assets where a person has the economic rights and control—such as the right to receive dividends and to direct voting—even if legal title is held in another name. Think of it like having the keys and using a car that’s registered to someone else: you get the benefits and make decisions. Investors care because beneficial ownership reveals who truly controls value and voting power, affecting corporate decisions and takeover dynamics.

Sole Voting Power financial

"5 | Sole Voting Power 13,849,022.00 6 | Shared Voting Power 0.00"

Sole voting power is the exclusive right to cast votes attached to a shareholder’s stock without needing approval from anyone else. Like holding the only remote control for a TV, it lets that holder decide corporate matters such as board members, mergers, and policy changes, making it important to investors because it concentrates control and can strongly influence a company’s strategy and the value of its shares.

Sole Dispositive Power financial

"7 | Sole Dispositive Power 14,232,545.00 8 | Shared Dispositive Power 0.00"

Sole dispositive power is the exclusive legal authority to decide what happens to a security — for example, whether to sell, transfer, or retain shares — without needing anyone else’s permission. Investors care because it signals who truly controls the economic outcome of an investment: like holding the only key to a safe, the holder can realize gains or losses and may trigger regulatory reporting, insider rules, or influence over corporate ownership.

Schedule 13G regulatory

"In accordance with SEC Release No. 34-39538 this schedule reflects the securities"

A Schedule 13G is a formal document that investors file with the government when they acquire a large ownership stake in a company, usually for investment purposes rather than control. It helps keep the public informed about who owns significant parts of a company's shares, which can influence how the company is managed and how investors make decisions. Filing this schedule is important for transparency and understanding the ownership landscape of publicly traded companies.

parent holding company financial

"Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company"

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What percentage of Arrowhead Pharmaceuticals (ARWR) does BlackRock currently report owning?

BlackRock reports beneficial ownership of 10.1% of Arrowhead Pharmaceuticals’ common stock. This represents a sizable institutional position and is disclosed in an amended Schedule 13G filing covering 14,232,545 shares of ARWR common stock.

How many Arrowhead Pharmaceuticals (ARWR) shares does BlackRock beneficially own?

BlackRock beneficially owns 14,232,545 shares of Arrowhead Pharmaceuticals common stock. This ownership gives BlackRock a reported 10.1% stake in the company, with most of these shares subject to BlackRock’s sole dispositive and voting authority.

What voting power does BlackRock have over its Arrowhead Pharmaceuticals (ARWR) shares?

BlackRock has sole voting power over 13,849,022 Arrowhead Pharmaceuticals shares and no shared voting power. This means BlackRock alone can vote or direct the vote on nearly all of the shares it reports owning in ARWR.

Does any single BlackRock client hold more than 5% of Arrowhead Pharmaceuticals (ARWR)?

No individual client holds more than 5% of Arrowhead Pharmaceuticals’ outstanding common shares. Various persons have rights to dividends or sale proceeds on the shares managed by BlackRock, but each such interest is below the 5% threshold.

What type of filing did BlackRock submit regarding Arrowhead Pharmaceuticals (ARWR)?

BlackRock submitted an Amendment No. 6 to Schedule 13G for Arrowhead Pharmaceuticals. This passive ownership report updates its beneficial holdings, voting power, and dispositive power over ARWR common stock as of the reported date.

Who signed the BlackRock ownership report for Arrowhead Pharmaceuticals (ARWR)?

The report was signed by Spencer Fleming, a Managing Director at BlackRock. The signature confirms the accuracy of the disclosed beneficial ownership, voting power, and dispositive power information relating to ARWR shares.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Available on EDGAR 07/27/2026 - 04:27 PM Accepted by SEC EDGAR 07/27/2026 - 04:25 PM Learn about SEC filing dates

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

(Amendment No. 6)

ARROWHEAD PHARMACEUTICALS INC

(Name of Issuer)

Common Stock

(Title of Class of Securities)

04280A100

(CUSIP Number)

06/30/2026

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

Rule 13d-1(b)

Rule 13d-1(c)

Rule 13d-1(d)

schemaVersion:

SCHEDULE 13G

CUSIP Number(s): 04280A100

1

Names of Reporting Persons

BlackRock, Inc.

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 13,849,022.00
6	Shared Voting Power 0.00
7	Sole Dispositive Power 14,232,545.00
8	Shared Dispositive Power 0.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

14,232,545.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

10.1 %

12

Type of Reporting Person (See Instructions)

HC

SCHEDULE 13G

Item 1.
(a)	Name of issuer: ARROWHEAD PHARMACEUTICALS INC
(b)	Address of issuer's principal executive offices: 177 E COLORADO BLVD, SUITE 700 PASADENA CA 91105
Item 2.
(a)	Name of person filing: BlackRock, Inc. In accordance with SEC Release No. 34-39538 (January 12, 1998), this Schedule 13G reflects the securities beneficially owned, or deemed to be beneficially owned, by certain business units (collectively, the "Reporting Business Units") of BlackRock, Inc. and its subsidiaries and affiliates. It does not include securities, if any, beneficially owned by other business units whose beneficial ownership of securities are disaggregated from that of the Reporting Business Units in accordance with such release.
(b)	Address or principal business office or, if none, residence: BlackRock, Inc., 50 Hudson Yards New York, NY 10001
(c)	Citizenship: See Item 4 of Cover Page
(d)	Title of class of securities: Common Stock
(e)	CUSIP No.: 04280A100
Item 4.	Ownership
(a)	Amount beneficially owned: 14232545
(b)	Percent of class: 10.1 %
(c)	Number of shares as to which the person has:
	(i) Sole power to vote or to direct the vote: 13849022
	(ii) Shared power to vote or to direct the vote: 0
	(iii) Sole power to dispose or to direct the disposition of: 14232545
	(iv) Shared power to dispose or to direct the disposition of: 0
Item 5.	Ownership of 5 Percent or Less of a Class.
	Not Applicable
Item 6.	Ownership of more than 5 Percent on Behalf of Another Person.
	If any other person is known to have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, such securities, a statement to that effect should be included in response to this item and, if such interest relates to more than 5 percent of the class, such person should be identified. A listing of the shareholders of an investment company registered under the Investment Company Act of 1940 or the beneficiaries of employee benefit plan, pension fund or endowment fund is not required. Various persons have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of the common stock of ARROWHEAD PHARMACEUTICALS INC. No one person's interest in the common stock of ARROWHEAD PHARMACEUTICALS INC is more than five percent of the total outstanding common shares.
Item 7.	Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
	If a parent holding company has filed this schedule, pursuant to Rule 13d-1(b)(ii)(G), so indicate under Item 3(g) and attach an exhibit stating the identity and the Item 3 classification of the relevant subsidiary. If a parent holding company has filed this schedule pursuant to Rule 13d-1(c) or Rule 13d-1(d), attach an exhibit stating the identification of the relevant subsidiary. See Exhibit 99
Item 8.	Identification and Classification of Members of the Group.
	Not Applicable
Item 9.	Notice of Dissolution of Group.
	Not Applicable

Item 10.

Certifications:

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

BlackRock, Inc.

Signature:	Spencer Fleming
Name/Title:	Managing Director
Date:	07/27/2026

Exhibit Information

Exhibit 24: Power of Attorney Exhibit 99: Item 7