On August 3, 2026, Anavex Life Sciences Corp. (“Anavex” or
the “Company”) issued a press release announcing plans to refresh Anavex’s Board of Directors (the “Board”)
at its 2026 Annual Meeting of Stockholders(the “Press Release”). The Press Release includes an open letter to Anavex’s
stockholders responding to the preliminary proxy statement filed by PVG Asset Management Corporation and Patrick S. Adams, which seeks
to replace the entire Anavex Board.
A copy of the Press Release is furnished as Exhibit 99.1 to this Current
Report and is incorporated herein by reference.
The information included in this Item 7.01, including Exhibit 99.1, shall
not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the “Exchange Act”),
or otherwise subject to the liabilities of that section, and it shall not be deemed incorporated by reference in any filing under the
Securities Act of 1933, as amended, or the Exchange Act, except as expressly set forth by specific reference in such filing.
Pursuant to the requirements of the Securities Exchange Act of 1934, the
registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

EXHIBIT 99.1
Anavex Life Sciences Announces Plans to Refresh
Board to Continue Overseeing Critical Progress
and Stockholder Value Creation
Nominates Two New Independent Directors, Mr. Gautam
Patel and Dr. Adrian Senderowicz,
Who Bring Deep, Relevant Experience in Life Sciences
Mr. Patel and Dr. Senderowicz to Stand for Election
at 2026 Annual Meeting with Independent Directors
Dr. Jiong Ma, Dr. Peter Donhauser, Dr. Axel Paeger and Dr. Claus van der Velden
Urges Stockholders to Reject Attempt by PVG Asset
Management Corporation and Patrick S. Adams to Acquire Control of the Company
Issues Open Letter to Stockholders and Files Preliminary
Proxy Statement
NEW YORK, NY, August 3, 2026 – Anavex Life Sciences Corp. (“Anavex”
or the “Company”) (Nasdaq: AVXL), a clinical-stage biopharmaceutical company focused on developing
innovative treatments for central nervous system (“CNS”) diseases with high unmet medical needs, today announced that
the Executive Committee of the Company’s Board of Directors (the “Executive Committee”) has taken significant steps
to continue overseeing critical progress to enhance stockholder value.
The Executive Committee announced that it is recommending a refreshed slate
of directors to the Company’s stockholders through the nomination of two new independent candidates, Mr. Gautam Patel and Dr. Adrian
Senderowicz. In identifying these candidates, the Board focused on individuals whose experience aligns with the company’s strategic
priorities. Mr. Patel and Dr. Senderowicz bring significant life sciences industry experience across leadership, strategy and drug development
at the executive and Board levels, as well as expertise in capital markets, clinical development and FDA regulatory matters that the Board
believes will support the Company’s growth and advance programs toward market approval and commercialization.
Mr. Patel and Dr. Senderowicz, along with independent chairperson Dr. Jiong
Ma, and independent directors Dr. Peter Donhauser, Dr. Axel Paeger and Dr. Claus van der Velden, will comprise the six Anavex nominees
standing for reelection at the 2026 Annual Meeting of Stockholders (the “2026 Annual Meeting”). Dr. Christopher Missling,
former Chief Executive Officer of Anavex, who refused to step down from the Board upon his termination “for cause”, and independent
director Dr. Steffen Thomas, have not been renominated for election and will no longer be members of the Board after the 2026 Annual Meeting.
In connection with the 2026 Annual Meeting, Anavex filed its preliminary
proxy statement with the Securities and Exchange Commission (the “SEC”) on July 31, 2026. As further described in
the preliminary proxy statement, the Anavex Board has established an Executive Committee to exercise the power of the Board in the management
of the business and affairs of the Company. The Executive Committee consists of Dr. Jiong Ma, Dr. Axel Paeger and Dr. Claus van der Velden.
Anavex’s preliminary proxy statement and, after the filing thereof, its definitive proxy statement can be accessed for free by visiting
EDGAR on the SEC website at www.SEC.gov. Once Anavex files its definitive proxy materials with the SEC, they will also be mailed to stockholders
and will include a WHITE proxy card with instructions on how to vote FOR all six Anavex nominees comprising the refreshed
Anavex Board. Your vote FOR all six Anavex nominees comprising the refreshed Anavex Board on the WHITE card will be critical.
The current Anavex Board members standing for reelection at the 2026 Annual
Meeting issued the following open letter to Anavex stockholders:
Dear Valued Anavex Stockholders,
Your current Board members standing for
election at the 2026 Annual Meeting have taken decisive action to stabilize the Company and create value for stockholders, including working
with the management team that is executing a strategy focusing on our lead candidate for patients with Alzheimer’s disease, oral
blarcamesine (ANAVEX®2-73) and identifying and nominating Mr. Patel and Dr. Senderowicz as highly qualified candidates for election
to the Board. The Company continues to have a strong cash runway and no long-term debt, and we are focused on ensuring we maximize our
use of capital and deliver on our goal of enhancing stockholder value.
We are working with urgency while ensuring the Company’s
operations continue without disruption following our termination “for cause” of former CEO Christopher Missling and the resulting
delay in filing Anavex’s quarterly report with the SEC. We appointed Dr. Terrie Kellmeyer, the Company’s former Senior Vice
President of Clinical Development and a Senior Advisor to Anavex, as interim CEO to oversee this period of transition. Dr. Kellmeyer spent
her entire career in drug development building and leading clinical and regulatory functions across the full lifecycle of drug development.
We are confident she is the right person to support the Company at this time.
Your Refreshed Anavex Board
Your current Board members standing for reelection are entirely
independent and will continue to bring critical institutional knowledge that we believe will advance the right path forward. Following
a thorough search process, we are also nominating two new, independent candidates, Mr. Gautam Patel and Dr. Adrian Senderowicz, who will
bring significant, relevant life sciences experience and complementary skills to the Board that are expected to immediately contribute
to the Company’s strategy and help create value across the business. Upon election, half of the Anavex Board will have been refreshed
since February 2026, and all of the Board members will be independent.
The four independent Anavex directors and two independent nominees
standing for election are:
| ● | Dr. Jiong Ma (Independent Chairperson), who has over 30 years of experience investing in, building and scaling technology
and life-sciences companies globally and brings deep financial, transactional and capital markets expertise to the Board. She has substantial
experience investing in, partnering with and working with management teams to set strategy for disruptive technology and life sciences
companies to shape the business, accelerate growth and drive long-term stockholder value. |
| ● | Dr. Peter Donhauser, a physician and clinical research leader with more than 20 years of experience in integrated medical care,
clinical trial oversight and private practice leadership, leading research across numerous trials for some of the world’s leading
global pharmaceutical companies. He has practiced osteopathic medicine in private practice since 2000, specializing in an integrated approach
to patient care, providing the Board with valuable clinical and patient-centered expertise. |
| ● | Dr. Axel Paeger, an experienced healthcare executive and corporate leader with more than 30 years of clinical, operational
and executive leadership experience. Dr. Paeger currently serves as Chief Executive Officer of AMEOS Group, which he founded as a start-up
in 2002 and scaled into one of Europe’s leading healthcare providers. He is a medically trained executive leader who brings deep
experience in healthcare to the Board. |
| ● | Mr. Gautam Patel, an experienced investment executive with over 30 years of corporate finance, investment management and board
leadership experience. Mr. Patel brings extensive capital allocation, investment and financial advisory expertise to the Board, with a
proven track record of executing growth-focused investments and guiding corporate strategy across the life sciences, financial services
and technology sectors. |
| ● | Dr. Adrian Senderowicz, an accomplished pharmaceutical executive and physician-scientist with over 30 years of clinical and
regulatory leadership experience across the life sciences industry. Dr. Senderowicz brings deep drug development, clinical research and
global regulatory expertise to the Board, with a proven track record of advancing novel therapeutics through critical international approvals
to drive growth and long-term value. |
| ● | Dr. Claus van der Velden, an accomplished finance executive with more than two decades of experience leading finance, governance
and enterprise oversight functions for publicly traded and technology-driven companies in Germany. Since May 2021, he has served as Chief
Financial Officer and Managing Director of NetCologne GmbH, a regional telecommunications provider in Germany. |
The Current Anavex Board Members Standing for Reelection are Advancing a Clear Plan to Create Stockholder Value
We have taken steps to address governance at the Board-level
and established interim leadership of the Company. The current Anavex Board members standing for reelection are highly engaged with leadership
and helping oversee continued progress of Anavex’s development pipeline.
The business update we provided on July 30 underscores that we
remain firmly committed to the Company’s lead candidate oral blarcamesine (ANAVEX®2-73) for patients with Alzheimer's disease,
and we are prioritizing engagement with the U.S. FDA to align on a clear, data-driven regulatory and clinical development strategy.
With our support, Anavex is prioritizing programs that the Company
believes have the greatest potential for success. The Company’s strategy concentrates resources on blarcamesine across three CNS
indications: early Alzheimer's disease and Rett syndrome, where the clinical and regulatory foundation is most advanced, and on Fragile
X syndrome, where FDA Orphan Drug Designation, supportive preclinical and biomarker data, and the absence of any approved therapy create
a promising regulatory path with the FDA.
We are highly confident in the path ahead for the Company and
the potential of our drug pipeline to improve the lives of patients while driving value for stockholders.
We Urge Stockholders to Reject the Attempt by PVG Asset Management
Corporation and
Patrick Adams to Take Control of the Company
On July 24, 2026, Patrick Adams and his firm PVG Asset Management
Corporation (“PVG”) filed a preliminary proxy statement with the SEC (the “PVG Proxy Statement”) seeking to replace
the entire Board of Anavex. We believe the PVG Proxy Statement is significantly deficient, does not comply with applicable SEC rules and
regulations, includes misleading statements and omits material information. Among other things, it provides insufficient information with
respect to PVG, Mr. Adams and the other director nominees, their background and security ownership, agreements with third parties with
respect to the proxy solicitation and other critical information necessary for our stockholders to evaluate the qualifications of the
nominees (or the lack thereof) and conflicts of interest. In addition, the PVG Proxy Statement lacks any discussion of any plan or strategy
for Anavex going forward, which leads us to conclude that PVG and Mr. Adams are seeking to gain effective control of the Company without
paying you a premium for your investment, despite only owning 0.35% of the Company’s outstanding shares of common stock as of July
30, 2026.
We believe that electing Mr. Adams or any of his nominees would
be highly risky and potentially value destructive by creating further disruption at this critical time for the Company.
Anavex’s preliminary proxy statement and, after the filing
thereof, its definitive proxy statement can be accessed for free by visiting EDGAR on the SEC website at www.SEC.gov. Once Anavex files
its definitive proxy materials with the SEC, they will also be mailed to stockholders and include a WHITE proxy card with instructions
on how to vote FOR all six directors comprising the refreshed Anavex Board. Your vote FOR all six directors comprising the
refreshed Anavex Board on the WHITE card will be critical.
We look forward to engaging with investors as we move toward
the 2026 Annual Meeting and are unwavering in our commitment to act in the best interests of the Company and all stockholders.
Sincerely,
Dr. Jiong Ma
Independent Chair |
Dr. Peter Donhauser
Independent Director |
Dr. Axel Paeger
Independent Director |
Dr. Claus van der Velden
Independent Director |
About Anavex Life Sciences Corp.
Anavex Life Sciences Corp. (Nasdaq: AVXL) is a publicly traded biopharmaceutical
company dedicated to the development of novel therapeutics for the treatment of neurodegenerative, neurodevelopmental, and neuropsychiatric
disorders. Further information is available at www.anavex.com.
Forward-Looking Statements
This press release contains forward-looking statements within the meaning
of the Private Securities Litigation Reform Act of 1995. Statements that are not historical facts, including statements regarding the
Company’s plans, strategies and expectations regarding the 2026 Annual Meeting, director nominations, the proxy solicitation, the
Company’s go-forward strategy, clinical development programs, business prospects, and potential actions of the Board and the Executive
Committee, are forward-looking statements. These statements can be identified by the use of forward-looking terminology, including the
words “believes,” “anticipates,” “plans,” “estimates,” “expects,” “intends,”
“may,” “will,” “would,” “could” and similar expressions, or the negative thereof. Many
factors may cause actual results to differ materially from those projected in any of such forward-looking statements, including the risks
and uncertainties set forth in the Company’s Annual Report on Form 10-K for the fiscal year ended September 30, 2025, and subsequent
filings and furnishings with the SEC, which should be considered together with any forward-looking statement. Readers are cautioned not
to place undue reliance on these forward-looking statements, which speak only as of the date hereof. All forward-looking statements are
qualified in their entirety by this cautionary statement, and Anavex Life Sciences Corp. undertakes no obligation to revise or update
this press release to reflect events or circumstances after the date hereof except as required by law.
Important Additional Information and Where to Find It
The Company intends to file a definitive proxy statement on Schedule 14A,
an accompanying WHITE proxy card, and other relevant documents with the SEC in connection with the solicitation of proxies from the Company’s
stockholders for the 2026 Annual Meeting. THE COMPANY’S STOCKHOLDERS ARE STRONGLY ENCOURAGED TO READ THE COMPANY’S DEFINITIVE
PROXY STATEMENT (INCLUDING ANY AMENDMENTS OR SUPPLEMENTS THERETO), THE ACCOMPANYING WHITE PROXY CARD AND OTHER DOCUMENTS FILED WITH THE
SEC CAREFULLY AND IN THEIR ENTIRETY WHEN THEY BECOME AVAILABLE BECAUSE THEY WILL CONTAIN IMPORTANT INFORMATION. Stockholders will be able
to obtain the definitive proxy statement, any amendments or supplements to the proxy statement and other documents that the Company files
with the SEC at no charge at the SEC’s website at www.sec.gov. Copies will also be available at no charge at the Company’s
website at www.anavex.com.
Certain Information Regarding Participants
The Company, its directors and certain of its executive officers may be
deemed to be “participants” (as defined in Schedule 14A under the Securities Exchange Act of 1934, as amended) in the solicitation
of proxies from the Company’s stockholders in connection with the matters to be considered at the 2026 Annual Meeting. Information
regarding the names of the Company’s directors and executive officers and certain other individuals and their direct or indirect
interests in the Company, by security holdings or otherwise, is set forth in the sections entitled “Compensation of Directors,”
“Executive Compensation,” and “Security Ownership of Certain Beneficial Owners and Management and Related Stockholder
Matters” of the Company’s Annual Report on Form 10-K for the fiscal year ended September 30, 2025 (available here), and any
subsequent filings on Forms 3, 4 and 5 filed with the SEC. Additional information regarding the identity of potential participants, and
their direct or indirect interests, by security holdings or otherwise, will be set forth in the Company’s definitive proxy statement
for the 2026 Annual Meeting when it is filed with the SEC. These documents are available free of charge at the SEC’s website at
www.sec.gov.
Investor Relations:
SCR Partners, LLC
Alex Arzeno
Tel: 203-550-3972
Email: alex@scr-ir.com
Tripp Sullivan
Tel: 615-942-7077
Email: tsullivan@scr-ir.com
For Media:
Collected Strategies
Nick Lamplough / Dylan O’Keefe
AVXL-CS@collectedstrategies.com