[144] Axsome Therapeutics, Inc. SEC Filing

Rhea-AI Filing Summary

Axsome Therapeutics, Inc. (AXSM) filed a Form 144 reporting a proposed sale of 45,783 common shares with an aggregate market value of $5,241,305.00. The filing lists Charles Schwab & Co., Inc. as the broker and names NASDAQ as the exchange, with an approximate sale date of 09/16/2025. The seller acquired 5,783 shares on 05/29/2024 via exercise and hold paid in cash, and 40,000 shares on 09/16/2025 via an employee stock option exercise using a broker cashless exercise. The filer certifies no undisclosed material adverse information.

Positive

• Filing provides clear compliance with Rule 144 requirements including broker, exchange, share counts, and acquisition details
• Transparency on acquisition method (cash payment for 5,783 shares and broker cashless exercise for 40,000 shares) clarifies insider transaction mechanics

Negative

• None.

Insights

Securities Analyst

TL;DR: Routine insider sale notice covering 45,783 shares (~0.09% of outstanding), likely procedural and not market-moving.

The Form 144 documents a proposed disposition under Rule 144 through Charles Schwab with an approximate trade date of 09/16/2025. The size of the proposed sale—45,783 shares against 49,901,487 shares outstanding—is small in percentage terms and should be considered routine insider liquidity rather than a corporate event. The filing also discloses acquisition dates and the mix of cash and cashless exercise payments, which clarifies the insider's basis and execution method.

Corporate Governance Expert

TL;DR: Filing shows formal compliance with Rule 144 and includes representations about lack of undisclosed material information.

The notice includes required representations that the seller does not possess undisclosed material information and notes the use of a brokered cashless exercise for a portion of the shares. These disclosures align with standard governance and compliance practices for employee equity transactions. No sales in the prior three months are reported, and the filing includes broker and exchange details, supporting transparency.

Form 144 Filer Information	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 144 NOTICE OF PROPOSED SALE OF SECURITIES PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933
FORM 144

144: Filer Information

Filer CIK
Filer CCC
Is this a LIVE or TEST Filing?	LIVE TEST
Submission Contact Information
Name
Phone
E-Mail Address

144: Issuer Information

Name of Issuer

SEC File Number

Address of Issuer

Phone

Name of Person for Whose Account the Securities are To Be Sold

See the definition of "person" in paragraph (a) of Rule 144. Information is to be given not only as to the person for whose account the securities are to be sold but also as to all other persons included in that definition. In addition, information shall be given as to sales by all persons whose sales are required by paragraph (e) of Rule 144 to be aggregated with sales for the account of the person filing this notice.

Relationship to Issuer

144: Securities Information

Title of the Class of Securities To Be Sold	Name and Address of the Broker	Number of Shares or Other Units To Be Sold	Aggregate Market Value	Number of Shares or Other Units Outstanding	Approximate Date of Sale	Name the Securities Exchange
Common	Charles Schwab & Co., Inc. 3000 Schwab Way Westlake TX 76262	45783	5241305.00	49901487	09/16/2025	NASDAQ

Furnish the following information with respect to the acquisition of the securities to be sold and with respect to the payment of all or any part of the purchase price or other consideration therefor:

144: Securities To Be Sold

Title of the Class	Date you Acquired	Nature of Acquisition Transaction	Name of Person from Whom Acquired	Is this a Gift?	Date Donor Acquired	Amount of Securities Acquired	Date of Payment	Nature of Payment *
Common	05/29/2024	Exercise and Hold	Axsome Therapeutics, Inc.			5783	05/29/2024	Cash
Common	09/16/2025	Employee Stock Option Exercise	Axsome Therapeutics, Inc.			40000	09/16/2025	Broker Payment for Cashless Exercise

* If the securities were purchased and full payment therefor was not made in cash at the time of purchase, explain in the table or in a note thereto the nature of the consideration given. If the consideration consisted of any note or other obligation, or if payment was made in installments describe the arrangement and state when the note or other obligation was discharged in full or the last installment paid.

Furnish the following information as to all securities of the issuer sold during the past 3 months by the person for whose account the securities are to be sold.

144: Securities Sold During The Past 3 Months

Nothing to Report

144: Remarks and Signature

Remarks

Date of Notice

Date of Plan Adoption or Giving of Instruction, If Relying on Rule 10b5-1

ATTENTION:

The person for whose account the securities to which this notice relates are to be sold hereby represents by signing this notice that he does not know any material adverse information in regard to the current and prospective operations of the Issuer of the securities to be sold which has not been publicly disclosed. If such person has adopted a written trading plan or given trading instructions to satisfy Rule 10b5-1 under the Exchange Act, by signing the form and indicating the date that the plan was adopted or the instruction given, that person makes such representation as of the plan adoption or instruction date.

Signature

ATTENTION: Intentional misstatements or omission of facts constitute Federal Criminal Violations (See 18 U.S.C. 1001)

FAQ

What does Axsome's Form 144 report for AXSM?

The filing reports a proposed sale of 45,783 common shares with an aggregate market value of $5,241,305.00 and an approximate sale date of 09/16/2025.

Who is the broker handling the AXSM sale?

The broker listed is Charles Schwab & Co., Inc. with an address noted in Westlake, TX.

How many AXSM shares were acquired by the seller and how were they paid for?

The seller acquired 5,783 shares on 05/29/2024 via exercise paid in cash and 40,000 shares on 09/16/2025 via an employee stock option exercise using a broker cashless exercise.

Does the filing report any shares sold in the past three months?

No. The section for securities sold during the past three months states Nothing to Report.

What exchange will the AXSM shares be sold on?

The filing indicates the shares are to be sold on NASDAQ.