Axsome Therapeutics, Inc. Insider Trading Activity

Maizel Ari reported acquisition or exercise transactions in this Form 4 filing.

Rhea-AI Filing Summary

Maizel Ari reported acquisition or exercise transactions in this Form 4 filing.

Axsome Therapeutics, Inc. reported that Chief Commercial Officer Ari Maizel received a grant of 7,224 Performance Stock Units (PSUs). Each PSU represents a contingent right to one share of common stock.

The PSUs vest only if specified sales and commercial launch milestones are achieved and if Maizel remains in service on each vesting date, making this a performance-based, at-risk equity award rather than an immediate share issuance.

Insider Trade Summary

Grant/Award: 7,224 shares

Grant/Award 1 txn

Insider Maizel Ari

Role Chief Commercial Officer

Type	Security	Shares	Price	Value
Grant/Award	Performance Stock Units	7,224	$0.00	$0.00

Holdings After Transaction: Performance Stock Units — 7,224 contracts (Direct)

Footnotes (2)

1. F1. Each performance stock unit ("PSU") represents a contingent right to receive one share of the Issuer's common stock.
2. F2. Each PSU will vest upon achievement of certain sales and commercial launch milestones, subject to the reporting person's continued service as of each vesting date.

Key Figures

Performance Stock Units granted: 7,224 units PSUs following transaction: 7,224 units PSU-to-share ratio: 1 PSU : 1 share

3 metrics

Performance Stock Units granted 7,224 units Grant of PSUs to Chief Commercial Officer on 2026-04-21

PSUs following transaction 7,224 units Total Performance Stock Units directly held after the grant

PSU-to-share ratio 1 PSU : 1 share Each performance stock unit represents one potential common share

Key Terms

Performance Stock Units, PSU, vesting, commercial launch milestones

4 terms

Performance Stock Units financial

"security_title: "Performance Stock Units""

Performance stock units are a type of company award that grants employees shares of stock only if certain performance goals are met. They motivate employees to work toward specific company achievements, aligning their interests with those of shareholders. For investors, they can influence a company's future stock supply and reflect management’s confidence in reaching key targets.

PSU financial

"Each performance stock unit ("PSU") represents a contingent right"

A PSU is a company where the government owns a controlling stake and often plays a direct role in its management and strategy. Think of it like a business that operates with public oversight, similar to a town-run utility versus a private neighborhood service. Investors watch PSUs differently because government involvement can affect profits, dividend policies, regulatory treatment and stability, so these stocks may behave more like policy instruments than pure market-driven enterprises.

vesting financial

"Each PSU will vest upon achievement of certain sales and commercial launch milestones"

Vesting is the process by which you earn full ownership of something, like company stock or a retirement benefit, over time. It’s like earning the right to keep a gift piece by piece the longer you stay with a company, making sure employees stay committed before they receive all the benefits.

commercial launch milestones financial

"upon achievement of certain sales and commercial launch milestones"

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What insider transaction did Axsome Therapeutics (AXSM) report for Ari Maizel?

Axsome reported that Chief Commercial Officer Ari Maizel received a grant of 7,224 Performance Stock Units. These units are derivative equity awards that can convert into common stock if specific performance conditions and continued service requirements are met over time.

What are the terms of the 7,224 Performance Stock Units granted at Axsome Therapeutics (AXSM)?

Each Performance Stock Unit represents a contingent right to receive one share of Axsome common stock. The units will vest only upon achievement of defined sales and commercial launch milestones, and require the executive to remain in service on each applicable vesting date.

Does the Form 4 filing show Ari Maizel buying or selling AXSM shares?

The filing does not show any open-market buying or selling of AXSM shares. It reports a compensation-related acquisition: a grant of 7,224 Performance Stock Units, which may settle in common stock only if performance and service-based vesting conditions are satisfied.

How many Axsome Therapeutics (AXSM) Performance Stock Units does Ari Maizel hold after this grant?

Following the reported transaction, Ari Maizel holds 7,224 Performance Stock Units directly. These units are performance-based awards, each tied to one potential share of common stock, subject to achieving specified sales and commercial launch milestones and satisfying continued service requirements.

What performance conditions apply to the Axsome Therapeutics (AXSM) PSUs granted to Ari Maizel?

The Performance Stock Units vest only when certain sales and commercial launch milestones are achieved. Vesting also depends on Maizel’s continued service with Axsome as of each vesting date, aligning the award with both company execution and executive retention.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Accepted by SEC EDGAR 04/23/2026 - 09:01 PM EDT Learn about SEC filing dates

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Maizel Ari

(Last) (First) (Middle)

C/O AXSOME THERAPEUTICS, INC.

ONE WORLD TRADE CENTER, 29TH FLOOR

(Street)

NEW YORK NEW YORK 10007

(City) (State) (Zip)

UNITED STATES

(Country)

2. Issuer Name and Ticker or Trading Symbol
Axsome Therapeutics, Inc. [ AXSM ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	Chief Commercial Officer

2a. Foreign Trading Symbol

3. Date of Earliest Transaction (Month/Day/Year)
04/21/2026

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
Performance Stock Units	(1)	04/21/2026		A		7,224		(2)	(2)	Common Stock	7,224	$0	7,224	D

Explanation of Responses:

1. Each performance stock unit ("PSU") represents a contingent right to receive one share of the Issuer's common stock.

2. Each PSU will vest upon achievement of certain sales and commercial launch milestones, subject to the reporting person's continued service as of each vesting date.

	/s/ Ari Maizel	04/23/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)