BlackRock, Inc. (AXSM) reports 2.74M Axsome Therapeutics shares in Schedule 13G/A

Rhea-AI Filing Summary

BlackRock, Inc. filed Amendment No. 5 reporting its beneficial ownership of common stock of Axsome Therapeutics, Inc.. BlackRock reports beneficial ownership of 2,736,503 shares of Axsome common stock, representing 5.3% of the outstanding class as of the reporting date.

BlackRock has sole voting power over 2,649,256 shares and sole dispositive power over 2,736,503 shares, with no shared voting or dispositive power. Various underlying clients and investors may have rights to dividends or sale proceeds, but no single such person has more than five percent of Axsome’s outstanding common shares.

Key Figures

Beneficially owned shares: 2,736,503 shares Ownership percentage: 5.3% Sole voting power: 2,649,256 shares +3 more

6 metrics

Beneficially owned shares 2,736,503 shares Common stock of Axsome Therapeutics beneficially owned by BlackRock, Inc.

Ownership percentage 5.3% Percent of Axsome Therapeutics common stock class held by BlackRock, Inc.

Sole voting power 2,649,256 shares Shares of Axsome Therapeutics over which BlackRock has sole voting power

Shared voting power 0 shares Shares of Axsome Therapeutics over which BlackRock has shared voting power

Sole dispositive power 2,736,503 shares Shares of Axsome Therapeutics over which BlackRock has sole dispositive power

Shared dispositive power 0 shares Shares of Axsome Therapeutics over which BlackRock has shared dispositive power

Key Terms

beneficially owned, sole voting power, sole dispositive power, Schedule 13G, +2 more

6 terms

beneficially owned financial

"this reflects the securities beneficially owned, or deemed to be beneficially owned"

Beneficially owned describes securities or assets where a person has the economic rights and control—such as the right to receive dividends and to direct voting—even if legal title is held in another name. Think of it like having the keys and using a car that’s registered to someone else: you get the benefits and make decisions. Investors care because beneficial ownership reveals who truly controls value and voting power, affecting corporate decisions and takeover dynamics.

sole voting power financial

"Sole Voting Power 2,649,256.00"

Sole voting power is the exclusive right to cast votes attached to a shareholder’s stock without needing approval from anyone else. Like holding the only remote control for a TV, it lets that holder decide corporate matters such as board members, mergers, and policy changes, making it important to investors because it concentrates control and can strongly influence a company’s strategy and the value of its shares.

sole dispositive power financial

"Sole Dispositive Power 2,736,503.00"

Sole dispositive power is the exclusive legal authority to decide what happens to a security — for example, whether to sell, transfer, or retain shares — without needing anyone else’s permission. Investors care because it signals who truly controls the economic outcome of an investment: like holding the only key to a safe, the holder can realize gains or losses and may trigger regulatory reporting, insider rules, or influence over corporate ownership.

Schedule 13G regulatory

"A listing of the shareholders of an investment company registered under the Investment Company Act of 1940"

A Schedule 13G is a formal document that investors file with the government when they acquire a large ownership stake in a company, usually for investment purposes rather than control. It helps keep the public informed about who owns significant parts of a company's shares, which can influence how the company is managed and how investors make decisions. Filing this schedule is important for transparency and understanding the ownership landscape of publicly traded companies.

parent holding company financial

"If a parent holding company has filed this schedule"

Power of Attorney regulatory

"Exhibit 24: Power of Attorney"

A power of attorney is a legal document that allows one person to make decisions and act on behalf of another person, often in financial or legal matters. It’s like giving someone a trusted helper or agent the authority to handle important tasks if you are unable to do so yourself. This matters to investors because it can impact how their assets are managed or transferred if they become unable to oversee their affairs.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Available on EDGAR 07/27/2026 - 04:26 PM Accepted by SEC EDGAR 07/27/2026 - 04:25 PM Learn about SEC filing dates

FAQ

What percentage of Axsome Therapeutics (AXSM) does BlackRock currently report owning?

BlackRock reports beneficial ownership of 5.3% of Axsome Therapeutics’ common stock. This represents a significant institutional position and is based on 2,736,503 shares beneficially owned as disclosed in Amendment No. 5 to its Schedule 13G.

How many Axsome Therapeutics (AXSM) shares does BlackRock report as beneficially owned?

BlackRock reports beneficial ownership of 2,736,503 shares of Axsome Therapeutics common stock. This share amount corresponds to 5.3% of the outstanding class and reflects holdings aggregated across specified BlackRock business units.

What voting power does BlackRock have over its Axsome Therapeutics (AXSM) shares?

BlackRock has sole voting power over 2,649,256 shares of Axsome Therapeutics and no shared voting power. It also reports sole dispositive power over 2,736,503 shares, meaning decisions to sell or hold these shares rest with BlackRock-related entities.

Does any BlackRock client hold more than 5% of Axsome Therapeutics (AXSM) shares?

No individual client or underlying person has more than 5% of Axsome’s outstanding common shares. Various persons may receive dividends or sale proceeds from the reported shares, but each such interest is below the five percent threshold.

Who filed the Schedule 13G/A for Axsome Therapeutics (AXSM) and what is the amendment number?

The filing was made by BlackRock, Inc. as Amendment No. 5 to a Schedule 13G. It updates BlackRock’s reported beneficial ownership and related voting and dispositive powers in Axsome Therapeutics’ common stock.

What is BlackRock’s dispositive power over Axsome Therapeutics (AXSM) shares?

BlackRock reports sole dispositive power over 2,736,503 shares of Axsome Therapeutics and no shared dispositive power. This indicates control by BlackRock-related entities over decisions to dispose of these shares.

SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

(Amendment No. 5)

Axsome Therapeutics, Inc.

(Name of Issuer)

Common Stock

(Title of Class of Securities)

05464T104

(CUSIP Number)

06/30/2026

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

Rule 13d-1(b)

Rule 13d-1(c)

Rule 13d-1(d)

schemaVersion:

SCHEDULE 13G

CUSIP Number(s): 05464T104

1

Names of Reporting Persons

BlackRock, Inc.

2

Check the appropriate box if a member of a Group (see instructions)

(a)
(b)

3

Sec Use Only

4

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 2,649,256.00
6	Shared Voting Power 0.00
7	Sole Dispositive Power 2,736,503.00
8	Shared Dispositive Power 0.00

9

Aggregate Amount Beneficially Owned by Each Reporting Person

2,736,503.00

10

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

11

Percent of class represented by amount in row (9)

5.3 %

12

Type of Reporting Person (See Instructions)

HC

SCHEDULE 13G

Item 1.
(a)	Name of issuer: Axsome Therapeutics, Inc.
(b)	Address of issuer's principal executive offices: ONE WORLD TRADE CENTER, 29TH FLOOR NEW YORK NY 10007
Item 2.
(a)	Name of person filing: BlackRock, Inc. In accordance with SEC Release No. 34-39538 (January 12, 1998), this Schedule 13G reflects the securities beneficially owned, or deemed to be beneficially owned, by certain business units (collectively, the "Reporting Business Units") of BlackRock, Inc. and its subsidiaries and affiliates. It does not include securities, if any, beneficially owned by other business units whose beneficial ownership of securities are disaggregated from that of the Reporting Business Units in accordance with such release.
(b)	Address or principal business office or, if none, residence: BlackRock, Inc., 50 Hudson Yards New York, NY 10001
(c)	Citizenship: See Item 4 of Cover Page
(d)	Title of class of securities: Common Stock
(e)	CUSIP No.: 05464T104
Item 3.	If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)	Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)	Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)	Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)	Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)	An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)	An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)	A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)	A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)	A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)	A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J), please specify the type of institution:
(k)	Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.	Ownership
(a)	Amount beneficially owned: 2736503
(b)	Percent of class: 5.3 %
(c)	Number of shares as to which the person has:
	(i) Sole power to vote or to direct the vote: 2649256
	(ii) Shared power to vote or to direct the vote: 0
	(iii) Sole power to dispose or to direct the disposition of: 2736503
	(iv) Shared power to dispose or to direct the disposition of: 0
Item 5.	Ownership of 5 Percent or Less of a Class.
	Not Applicable
Item 6.	Ownership of more than 5 Percent on Behalf of Another Person.
	If any other person is known to have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, such securities, a statement to that effect should be included in response to this item and, if such interest relates to more than 5 percent of the class, such person should be identified. A listing of the shareholders of an investment company registered under the Investment Company Act of 1940 or the beneficiaries of employee benefit plan, pension fund or endowment fund is not required. Various persons have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of the common stock of Axsome Therapeutics, Inc.. No one person's interest in the common stock of Axsome Therapeutics, Inc. is more than five percent of the total outstanding common shares.
Item 7.	Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
	If a parent holding company has filed this schedule, pursuant to Rule 13d-1(b)(ii)(G), so indicate under Item 3(g) and attach an exhibit stating the identity and the Item 3 classification of the relevant subsidiary. If a parent holding company has filed this schedule pursuant to Rule 13d-1(c) or Rule 13d-1(d), attach an exhibit stating the identification of the relevant subsidiary. See Exhibit 99
Item 8.	Identification and Classification of Members of the Group.
	Not Applicable
Item 9.	Notice of Dissolution of Group.
	Not Applicable

Item 10.

Certifications:

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

BlackRock, Inc.

Signature:	Spencer Fleming
Name/Title:	Managing Director
Date:	07/27/2026

Exhibit Information

Exhibit 24: Power of Attorney Exhibit 99: Item 7