FORM 6-K
 
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
 
Report of Foreign Issuer
 
Pursuant to Rule 13a-16 or 15d-16 of
the Securities Exchange Act of 1934
 
For the month of November 2025
 
Commission File Number: 001-11960
 
AstraZeneca PLC
 
1 Francis Crick Avenue
Cambridge Biomedical Campus
Cambridge CB2 0AA
United Kingdom
 
Indicate
by check mark whether the registrant files or will file annual reports under cover of Form 20-F or Form 40-F:
Form 20-F x Form 40-F ¨
 
Indicate
by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(1): ¨
 
Indicate
by check mark if the registrant is submitting the Form 6-K in paper as permitted by Regulation S-T Rule 101(b)(7): ¨
 
Indicate by check mark whether the registrant
by furnishing the information contained in this Form is also thereby furnishing the information to the Commission pursuant to Rule 12g3-2(b) under
the Securities Exchange Act of 1934.
Yes
¨ No x
 
If “Yes” is marked, indicate below
the file number assigned to the Registrant in connection with Rule 12g3-2(b): 82- __________
 
  
    
    
    
 
Exhibit List
 
  
    | Exhibit No. | 
    Description | 
  
    |   | 
      | 
  
    | 99.1 | 
    Articles of Association adopted by special resolution passed on 3 November 2025 | 
  
 
    
    
    
 
SIGNATURES
 
Pursuant to the requirements of the Securities
Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.
 
  
    |   | 
    ASTRAZENECA PLC | 
  
    |   | 
      | 
      | 
  
    | Date: November 3, 2025 | 
    By: | 
    /s/ Matthew Bowden | 
  
    |   | 
      | 
    Name: Matthew Bowden | 
  
    |   | 
      | 
    Title: Company Secretary  |