AstraZeneca officer Mani Sharma acquires 1 share

AstraZeneca PLC (AZN) officer Mani Sharma, SVP, Group Controller and Head of Global Finance Services, acquired 1 ordinary share on November 6, 2026, under the issuer’s Share Incentive Plan, at a stated price of GBP 139.29, converted to $186.24.

Available on EDGAR 11/10/2026 - 06:45 AM EST Accepted by SEC EDGAR 11/10/2026 - 06:44 AM EST Learn about SEC filing dates

Rhea-AI Filing Summary

AstraZeneca PLC (AZN) officer Mani Sharma, SVP, Group Controller and Head of Global Finance Services, acquired 1 ordinary share on November 6, 2026, under the issuer’s Share Incentive Plan, at a stated price of GBP 139.29, converted to $186.24. Mani Sharma’s direct holdings following the acquisition were 19,292 ordinary shares.

Insider Trade Summary

Grant/Award: 1 shares

Grant/Award 1 txn

Insider Sharma Mani

Role See remarks

Type	Security	Shares	Price	Value
Grant/Award	Ordinary Shares F1	1	$186.24	$186.24

Holdings After Transaction: Ordinary Shares — 19,291.6989 shares (Direct)

Footnotes (1)

1. F1. Represents the acquisition of shares pursuant to the Issuer's Share Incentive Plan at a price of GBP139.29, which has been converted from British pounds sterling to United States dollars at a conversion rate of GBP1.0000 to $1.3371 on November 6, 2026 as published by the Board of Governors of the Federal Reserve System.

Key Figures

Shares acquired: 1 ordinary share Stated price per share: GBP 139.29 Converted price per share: $186.24 +2 more

5 metrics

Shares acquired 1 ordinary share November 6, 2026

Stated price per share GBP 139.29 Acquisition under the Share Incentive Plan

Converted price per share $186.24 Converted from GBP 139.29

Currency conversion rate GBP 1.0000 to $1.3371 November 6, 2026

Direct holdings following acquisition 19,292 ordinary shares Following the reported acquisition

Key Terms

Share Incentive Plan, Ordinary Shares, conversion rate

3 terms

Share Incentive Plan financial

"pursuant to the Issuer's Share Incentive Plan"

A share incentive plan is a company program that gives employees or directors the chance to receive or buy company shares, often after staying with the firm or meeting performance goals. It matters to investors because it’s like giving workers a slice of the company pie to boost performance and loyalty, but issuing those slices can reduce each existing owner’s portion and change metrics such as earnings per share and share count.

Ordinary Shares financial

"Ordinary Shares"

Ordinary shares are a type of ownership stake in a company, giving shareholders a right to participate in the company’s profits and decision-making through voting. They are similar to owning a piece of a business, and their value can rise or fall based on the company's performance. Investors buy ordinary shares to potentially earn dividends and benefit from the company's growth over time.

conversion rate financial

"at a conversion rate of GBP1.0000 to $1.3371"

Conversion rate is the proportion of items, people or contracts that take a desired action out of the total possible — for example the share of website visitors who make a purchase, or the number of convertible bonds that are exchanged for shares. Investors care because it measures how effectively a business or financial instrument turns opportunity into real outcomes, like sales or share issuance, which directly affects revenue, cash flow and ownership dilution.

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

How many AZN shares did Mani Sharma acquire?

Mani Sharma acquired 1 ordinary share on November 6, 2026, under AstraZeneca’s Share Incentive Plan, at a stated price of GBP 139.29, converted to $186.24. His direct holdings following the acquisition were 19,292 ordinary shares.

AI-generated analysis. How Rhea-AI works. Not financial advice.

Form 4 Insider Transactions: What Each Field Means →

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SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Sharma Mani

(Last) (First) (Middle)

1 FRANCIS CRICK AVENUE

CAMBRIDGE BIOMEDICAL CAMPUS

(Street)

CAMBRIDGE CB2 0AA

(City) (State) (Zip)

UNITED KINGDOM

(Country)

2. Issuer Name and Ticker or Trading Symbol
ASTRAZENECA PLC [ AZN ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	See remarks

2a. Foreign Trading Symbol

3. Date of Earliest Transaction (Month/Day/Year)
11/06/2026

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Ordinary Shares	11/06/2026		A		1	A	$186.24(1)	19,291.6989	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. Represents the acquisition of shares pursuant to the Issuer's Share Incentive Plan at a price of GBP139.29, which has been converted from British pounds sterling to United States dollars at a conversion rate of GBP1.0000 to $1.3371 on November 6, 2026 as published by the Board of Governors of the Federal Reserve System.

Remarks:

SVP, Group Controller and Head of Global Finance Services

	/s/ Mani Sharma	11/10/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)