Welcome to our dedicated page for Beyondspring SEC filings (Ticker: BYSI), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.
BeyondSpring Inc. filings document the regulatory record of a clinical-stage biopharmaceutical company focused on cancer therapies, including Plinabulin development, financial results and capital structure. Its Form 10-K and Form 8-K disclosures cover audited consolidated financial statements, quarterly and annual operating results, clinical-program updates, and risk and business information tied to oncology development.
Current reports also record material agreements, registered offerings of ordinary shares, SEED Therapeutics financing and ownership disclosures, and shareholder-vote results from annual meetings. These filings describe governance actions, securities issuances, registration-statement use and other material events affecting BeyondSpring’s public-company reporting.
BeyondSpring Inc. announced a leadership transition centered on advancing its DUBLIN-4 confirmatory Phase 3 trial of Plinabulin for non-small cell lung cancer. Founder and CEO Dr. Lan Huang will step down as Chief Executive Officer effective July 1, 2026, remaining as Chair of the Board while dedicating her operational focus to SEED Therapeutics.
Min Qiu will become Chief Executive Officer and Na Li will become Chief Financial Officer on July 1, 2026, bringing capital markets and cross-border pharma experience. Director Dr. Jiangwen (Jen) Majeti will serve as Vice Chair and receive options to purchase 100,000 ordinary shares, vesting over four years under the 2017 Omnibus Incentive Plan. The company highlights DUBLIN-4, its 442-patient confirmatory Phase 3 study, and prior DUBLIN-3 results showing Plinabulin plus docetaxel doubled two- and three-year survival and reduced grade 4 neutropenia from 33% to 5%, as the strategic focus of the new leadership structure.
BeyondSpring Inc. director and CEO Lan Huang reported an indirect transfer of 260,582 Ordinary Shares as a bona fide gift by the Lan Huang 2022 Grantor Retained Annuity Trust, leaving that trust with no shares. Other indirect holdings remain, including 253,465 shares held by the 2026 SUNSHINE GRAT and 223,291 shares held by the 2024 SPIRIT GRAT for the benefit of Dr. Huang’s children.
BeyondSpring Inc. schedules updated ownership disclosure: This Amendment No. 9 to a Schedule 13G/A reports beneficial ownership and voting arrangements for certain affiliated entities and individuals. The filing states 41,119,820 Ordinary Shares outstanding as of March 31, 2026 and shows Lan Huang and Linqing Jia each beneficially owning 5,787,906 shares (14.1%) through a combination of direct holdings, affiliated entities, trusts and proxies. The filing details recent intra-family trust transfers of 260,582 and 253,465 shares and clarifies shared voting/dispositive arrangements among the reporting persons.
BeyondSpring Inc. reported a consolidated net loss of $6.7 million for the three months ended March 31, 2026, compared with net income of $1.2 million a year earlier, when results were boosted by a $7.0 million gain on a SEED share sale.
Continuing operations posted a net loss of $2.4 million as research and development expenses rose to $1.1 million and general and administrative costs declined to $1.2 million. Discontinued SEED operations generated a loss of $4.3 million, reflecting ongoing investment in its targeted protein degradation platform.
Cash and cash equivalents plus short-term investments from continuing operations totaled $7.9 million as of March 31, 2026, while deferred revenue of about $29.0 million from the Hengrui collaboration remained on the balance sheet. Management expects additional cash inflows from staged sales of SEED preferred shares and is evaluating financing and strategic alternatives.
BeyondSpring Inc. reported first-quarter 2026 results showing a shift from profit to loss while advancing its oncology pipeline. Net loss was $6.7 million for the quarter ended March 31, 2026, compared with net income of $1.2 million a year earlier, driven mainly by losses in discontinued operations.
From continuing operations, net loss narrowed slightly to $2.4 million from $2.6 million as research and development expenses rose to $1.1 million and general and administrative costs fell to $1.1 million. Cash, cash equivalents, and short-term investments totaled $7.9 million as of March 31, 2026, with shareholders’ deficit at $30.4 million.
Strategically, BeyondSpring highlighted new preclinical data suggesting its lead asset Plinabulin may enhance efficacy and tolerability of antibody-drug conjugate regimens, and announced that SEED Therapeutics advanced RBM39 molecular glue degrader ST-01156 into Phase 1 clinical development using a biomarker-driven approach.
BeyondSpring Inc. director Matthew Kirkby received a grant of stock options covering 23,902 ordinary shares. The options have an exercise price of $1.64 per share and expire on April 1, 2036. All options vest on April 1, 2027, contingent on his continuous service with the company.
BeyondSpring Inc. director Patrick Fabbio received a grant of stock options covering 22,165 ordinary shares. The options have an exercise price of $1.64 per share and were issued under the company’s 2017 Omnibus Incentive Plan as part of his compensation.
All 22,165 options vest on April 1, 2027, provided he continues serving the company through that date, and they expire on April 1, 2036. This is a compensation-related award, not an open-market purchase or sale of BeyondSpring shares.
BeyondSpring Inc. director Brendan Delaney received a grant of stock options for 20,427 ordinary shares on April 1, 2026 as equity compensation. The options have an exercise price of $1.64 per share and expire on April 1, 2036. All options vest on April 1, 2027, subject to his continuous service with the company through that date.
BeyondSpring Inc. director Majeti Jiangwen received a grant of stock options to purchase 21,730 Ordinary Shares of the company. These options have an exercise price of $1.64 per share and expire on April 1, 2036.
All of the options will vest on April 1, 2027, provided the director continues to serve the company through that date. Following this grant, the Form 4 shows holdings of 21,730 stock options directly owned.
BeyondSpring Inc. reported that Chief Scientific Officer Lu Yingjuan June received a grant of stock options for 17,840 ordinary shares. The options have an exercise price of $1.64 per share and expire on April 1, 2036.
According to the grant terms, 4,460 options will vest on each of April 1, 2027, April 1, 2028, April 1, 2029 and April 1, 2030, as long as she continues serving the company through those dates. All options were reported as directly owned following this award.