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Decheng/Dr. Cui Files Form 4 Reporting September 2025 Sales of BYSI Shares

Filing Impact
(Neutral)
Filing Sentiment
(Negative)
Form Type
4

Rhea-AI Filing Summary

Decheng Capital-related funds and manager Dr. Xiangmin Cui reported insider sales of BeyondSpring Inc. (BYSI) ordinary shares over three consecutive days in September 2025. The filings show Fund III sold 5,410 shares on 09/22/2025 at a weighted average price of $1.83, 4,106 shares on 09/23/2025 at $1.72, and 2,256 shares on 09/24/2025 at $1.68, for a total of 11,772 shares sold across the three transactions. After these sales, Fund III beneficially owned 1,847,561 shares. The Form 4 also discloses indirect holdings by affiliated vehicles: Fund II holds 1,617,409 shares and Decheng Capital Global Healthcare Fund (Master) holds 891,734 shares. The filings state the reported prices are weighted averages for multiple transactions within specified ranges and identify Decheng Capital management entities and Dr. Cui as the reporting persons.

Positive

  • Full disclosure provided: Form 4 includes detailed weighted-average price footnotes and signatures from each reporting entity.
  • Substantial retained holdings: Fund III still beneficially owns 1,847,561 shares after sales, with Fund II and Healthcare holding 1,617,409 and 891,734 shares respectively.

Negative

  • Insider selling activity: Decheng-related accounts sold a total of 11,772 ordinary shares across 09/22–09/24/2025.
  • Average sale prices low relative to typical retail levels: Weighted-average prices ranged from $1.68 to $1.83 (multiple transactions within disclosed ranges).

Insights

TL;DR: Routine insider disposals by Decheng funds, totaling 11,772 shares; holdings remain materially concentrated across affiliated funds.

The reported transactions are outright sales over three days with weighted-average prices between $1.68 and $1.83. Total shares sold (11,772) are small relative to the aggregated beneficial holdings disclosed (Fund III 1,847,561; Fund II 1,617,409; Healthcare 891,734). This pattern appears to be liquidity-taking rather than a change in control. The filing properly discloses indirect ownership through GP entities and includes standard disclaimers of beneficial ownership by the GPs and manager except for pecuniary interest.

TL;DR: Disclosures are consistent and complete for Section 16 reporting; multiple affiliated filers and signatures are provided.

The Form 4 identifies each reporting entity and the common manager, includes explanatory footnotes about weighted-average pricing, and contains signed attestations dated 09/24/2025. The filing shows appropriate aggregation of indirect holdings and clarifies disclaimers of beneficial ownership by GP entities. There are no indications of director departures, amendments, or other governance events in this Form 4.

SEC Form 4
FORM 4 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number: 3235-0287
Estimated average burden
hours per response: 0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
1. Name and Address of Reporting Person*
Decheng Capital China Life Sciences USD Fund III, L.P.

(Last) (First) (Middle)
C/O DECHENG CAPITAL
3000 SAND HILL ROAD, BLDG. 2, SUITE 110

(Street)
MENLO PARK CA 94025

(City) (State) (Zip)
2. Issuer Name and Ticker or Trading Symbol
BeyondSpring Inc. [ BYSI ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
Director X 10% Owner
Officer (give title below) Other (specify below)
3. Date of Earliest Transaction (Month/Day/Year)
09/22/2025
4. If Amendment, Date of Original Filed (Month/Day/Year)
6. Individual or Joint/Group Filing (Check Applicable Line)
Form filed by One Reporting Person
X Form filed by More than One Reporting Person
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Ordinary Shares 09/22/2025 S 5,410 D $1.83(1) 1,853,923 I By Decheng Capital China Life Sciences USD Fund III, L.P.(2)
Ordinary Shares 09/23/2025 S 4,106 D $1.72(3) 1,849,817 I By Decheng Capital China Life Sciences USD Fund III, L.P.(2)
Ordinary Shares 09/24/2025 S 2,256 D $1.68(4) 1,847,561 I By Decheng Capital China Life Sciences USD Fund III, L.P.(2)
Ordinary Shares 1,617,409 I By Decheng Capital China Life Sciences USD Fund II, L.P.(5)
Ordinary Shares 891,734 I By Decheng Capital Global Healthcare Fund (Master), LP(6)
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year) 7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
1. Name and Address of Reporting Person*
Decheng Capital China Life Sciences USD Fund III, L.P.

(Last) (First) (Middle)
C/O DECHENG CAPITAL
3000 SAND HILL ROAD, BLDG. 2, SUITE 110

(Street)
MENLO PARK CA 94025

(City) (State) (Zip)

Relationship of Reporting Person(s) to Issuer
Director X 10% Owner
Officer (give title below) Other (specify below)
1. Name and Address of Reporting Person*
Decheng Capital Management III (Cayman), LLC

(Last) (First) (Middle)
C/O DECHENG CAPITAL
3000 SAND HILL ROAD, BLDG. 2, SUITE 110

(Street)
MENLO PARK CA 94025

(City) (State) (Zip)

Relationship of Reporting Person(s) to Issuer
Director X 10% Owner
Officer (give title below) Other (specify below)
1. Name and Address of Reporting Person*
Decheng Capital China Life Sciences USD Fund II, L.P.

(Last) (First) (Middle)
C/O DECHENG CAPITAL
3000 SAND HILL ROAD, BLDG. 2, SUITE 110

(Street)
MENLO PARK CA 94025

(City) (State) (Zip)

Relationship of Reporting Person(s) to Issuer
Director X 10% Owner
Officer (give title below) Other (specify below)
1. Name and Address of Reporting Person*
Decheng Capital Global Healthcare Fund (Master), LP

(Last) (First) (Middle)
C/O DECHENG CAPITAL
3000 SAND HILL ROAD, BLDG. 2, SUITE 110

(Street)
MENLO PARK CA 94025

(City) (State) (Zip)

Relationship of Reporting Person(s) to Issuer
Director X 10% Owner
Officer (give title below) Other (specify below)
1. Name and Address of Reporting Person*
Decheng Capital Global Healthcare GP, LLC

(Last) (First) (Middle)
C/O DECHENG CAPITAL
3000 SAND HILL ROAD, BLDG. 2, SUITE 110

(Street)
MENLO PARK CA 94025

(City) (State) (Zip)

Relationship of Reporting Person(s) to Issuer
Director X 10% Owner
Officer (give title below) Other (specify below)
1. Name and Address of Reporting Person*
Cui Xiangmin

(Last) (First) (Middle)
C/O DECHENG CAPITAL
3000 SAND HILL ROAD, BLDG. 2, SUITE 110

(Street)
MENLO PARK CA 94025

(City) (State) (Zip)

Relationship of Reporting Person(s) to Issuer
Director X 10% Owner
Officer (give title below) Other (specify below)
Explanation of Responses:
1. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.75 to $1.89 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
2. These securities are held directly by Decheng Capital China Life Sciences USD Fund III, L.P. ("Fund III"). Decheng Capital Management III (Cayman), LLC ("GP III") is the general partner of Fund III. Dr. Cui is the manager of GP III. Each of Fund III, GP III and Dr. Cui may be deemed to beneficially own the securities held by Fund III. Each of GP III and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.
3. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.65 to $1.80 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
4. The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.67 to $1.70 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.
5. These securities are held directly by Decheng Capital China Life Sciences USD Fund II, L.P. ("Fund II"). Decheng Capital Management II (Cayman), LLC ("GP II") is the general partner of Fund II. Dr. Cui is the manager of GP II. Each of Fund II, GP II and Dr. Cui may be deemed to beneficially own the securities held by Fund II. Each of GP II and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.
6. These securities are held directly by Decheng Capital Global Healthcare Fund (Master), LP ("Healthcare"). Decheng Capital Global Healthcare GP, LLC ("Healthcare GP") is the general partner of Healthcare. Dr. Cui is the manager of Healthcare GP. Each of Healthcare GP and Dr. Cui may be deemed to beneficially own the securities held by Healthcare. Each of Healthcare GP and Dr. Cui disclaims beneficial ownership of these securities, except to the extent of its or his proportionate pecuniary interest therein.
Decheng Capital China Life Sciences USD Fund III, L.P., By Decheng Capital Management III (Cayman), LLC, its General Partner, By /s/ Xiangmin Cui, Manager 09/24/2025
Decheng Capital Management III (Cayman), LLC, By /s/Xiangmin Cui, Manager 09/24/2025
Decheng Capital China Life Sciences USD Fund II, L.P., By Decheng Capital Management II (Cayman), LLC, its General Partner, By /s/ Xiangmin Cui, Manager 09/24/2025
Decheng Capital Global Healthcare Fund (Master), LP, By Decheng Capital Global Healthcare GP, LLC, its General Partner, By Decheng Capital LLC, its Manager, By /s/ Xiangmin Cui, Manager 09/24/2025
Decheng Capital Global Healthcare GP, LLC, By Decheng Capital LLC, its Manager, By /s/ Xiangmin Cui, Manager 09/24/2025
/s/ Xiangmin Cui 09/24/2025
** Signature of Reporting Person Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What shares and volumes did Decheng Capital report selling in the BYSI Form 4?

The filing reports Decheng Capital China Life Sciences USD Fund III sold 5,410 shares on 09/22/2025, 4,106 shares on 09/23/2025, and 2,256 shares on 09/24/2025, totalling 11,772 shares.

At what prices were the BYSI shares sold according to the Form 4?

The Form 4 gives weighted-average prices: $1.83 on 09/22/2025, $1.72 on 09/23/2025, and $1.68 on 09/24/2025, with footnotes stating each is a weighted average across transactions in disclosed ranges.

Who is the reporting person and what is their relationship to BYSI?

The reporting persons are Decheng Capital funds and affiliated managers (e.g., Decheng Capital China Life Sciences USD Fund III, GP entities) and Dr. Xiangmin Cui; the filings mark the relationship as Director and show indirect beneficial ownership.

How many BYSI shares do Decheng-affiliated funds hold after these transactions?

Per the Form 4, after the reported sales Fund III beneficially owned 1,847,561 shares. Separately disclosed indirect holdings include Fund II with 1,617,409 shares and Healthcare (Master) with 891,734 shares.

Do the filings indicate any change in control or director departures at BYSI?

No. The Form 4 reports routine sales and discloses beneficial ownership and signatures but does not indicate any change in control or departures.

Are the reported prices exact transaction prices?

No. The filing states the reported prices are weighted averages for multiple transactions executed within stated price ranges and offers to provide detailed breakdowns on request.
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