Caris Life Sciences insider plans 478K share sale

Executive David Spetzler has filed a Rule 144 notice to sell 478,000 Caris Life Sciences shares tied to exercising expiring stock options.

Rhea-AI Filing Summary

Caris Life Sciences, Inc. (CAI) reports that David Spetzler has filed a notice of proposed sale of company common stock under Rule 144. The notice covers 478,000 shares of common stock, expected to be sold on September 3, 2026 in connection with the exercise of stock options under a registered plan.

The sales are to be executed through Morgan Stanley Smith Barney LLC Executive Financial Services, with settlement in cash. Spetzler notes he is selling sufficient shares to cover the option exercise cost and related taxes for an expiring option.

Key Figures

Shares proposed to be sold: 478,000 shares Proposed sale date: September 3, 2026 Notice date: September 3, 2026

3 metrics

Shares proposed to be sold 478,000 shares Common stock covered by the Rule 144 notice for David Spetzler

Proposed sale date September 3, 2026 Date associated with the sale and option exercise

Notice date September 3, 2026 Date of notice signed by David Spetzler

Key Terms

Rule 144, Exercise of Options Under a Registered Plan, expiring option

3 terms

Rule 144 regulatory

"See the definition of "person" in paragraph (a) of Rule 144."

Rule 144 is a U.S. securities regulation that sets conditions under which restricted or insider-held shares can be legally resold to the public, such as required holding periods, availability of public information, limits on how much can be sold at once, and certain filing requirements. For investors it matters because it determines when previously locked-up shares can enter the market — like a release valve that can increase supply, affect share price, and signal insider intent.

Exercise of Options Under a Registered Plan financial

"Common | 09/03/2026 | Exercise of Options Under a Registered Plan |"

expiring option financial

"exercise of an expiring option."

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What does the Form 144 filing disclose for Caris Life Sciences (CAI)?

It discloses that David Spetzler has filed a Rule 144 notice to sell 478,000 shares of Caris Life Sciences common stock on September 3, 2026, in connection with the exercise of stock options under a registered plan.

How many CAI shares are proposed to be sold under this Form 144?

The notice covers a proposed sale of 478,000 shares of Caris Life Sciences common stock. This amount appears both in the securities information and the securities-to-be-sold sections of the filing.

Why is David Spetzler selling Caris Life Sciences (CAI) shares?

The remarks state that the client is selling enough shares to cover the options cost and taxes associated with the exercise of an expiring option under a registered plan.

When is the CAI stock sale under this Form 144 expected to occur?

The Rule 144 notice identifies September 3, 2026 as the date associated with the proposed sale of the 478,000 Caris Life Sciences common shares and with the underlying option exercise.

Through which broker will the Caris Life Sciences (CAI) shares be sold?

The filing lists Morgan Stanley Smith Barney LLC Executive Financial Services, located at 1 New York Plaza, as the broker handling the proposed sale of the Caris Life Sciences common shares.

What is the source of the CAI shares being sold in this Form 144?

The securities to be sold are Caris Life Sciences common stock obtained via exercise of options under a registered plan, with the issuer identified as the source in the transaction description.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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Available on EDGAR 09/03/2026 - 05:14 PM EDT Accepted by SEC EDGAR 09/03/2026 - 04:45 PM EDT Learn about SEC filing dates

Form 144 Filer Information	UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 144 NOTICE OF PROPOSED SALE OF SECURITIES PURSUANT TO RULE 144 UNDER THE SECURITIES ACT OF 1933
FORM 144

144: Filer Information

Filer CIK	0002071953
Filer CCC	XXXXXXXX
Is this a LIVE or TEST Filing?	LIVE TEST
Submission Contact Information
Name
Phone
E-Mail Address

144: Issuer Information

Name of Issuer	CARIS LIFE SCIENCES, INC.
SEC File Number	001-42706
Address of Issuer	750 W JOHN CARPENTER FREEWAY SUITE 800 IRVING TEXAS 75039
Phone	(866) 771-8946
Name of Person for Whose Account the Securities are To Be Sold	DAVID SPETZLER
See the definition of "person" in paragraph (a) of Rule 144. Information is to be given not only as to the person for whose account the securities are to be sold but also as to all other persons included in that definition. In addition, information shall be given as to sales by all persons whose sales are required by paragraph (e) of Rule 144 to be aggregated with sales for the account of the person filing this notice.
Relationship to Issuer	Officer

144: Securities Information

Title of the Class of Securities To Be Sold	Name and Address of the Broker	Number of Shares or Other Units To Be Sold	Aggregate Market Value	Number of Shares or Other Units Outstanding	Approximate Date of Sale	Name the Securities Exchange
Common	Morgan Stanley Smith Barney LLC Executive Financial Services 1 New York Plaza 8th Floor New York NY 10004	478000	11882984.40	282595186	09/03/2026	NASDAQ

Furnish the following information with respect to the acquisition of the securities to be sold and with respect to the payment of all or any part of the purchase price or other consideration therefor:

144: Securities To Be Sold

Title of the Class	Date you Acquired	Nature of Acquisition Transaction	Name of Person from Whom Acquired	Is this a Gift?	Date Donor Acquired	Amount of Securities Acquired	Date of Payment	Nature of Payment *
Common	09/03/2026	Exercise of Options Under a Registered Plan	Issuer			478000	09/03/2026	Cash

* If the securities were purchased and full payment therefor was not made in cash at the time of purchase, explain in the table or in a note thereto the nature of the consideration given. If the consideration consisted of any note or other obligation, or if payment was made in installments describe the arrangement and state when the note or other obligation was discharged in full or the last installment paid.

Furnish the following information as to all securities of the issuer sold during the past 3 months by the person for whose account the securities are to be sold.

144: Securities Sold During The Past 3 Months

Nothing to Report

144: Remarks and Signature

Remarks	The client is selling enough shares to cover the options cost and taxes associated with the exercise of an expiring option.
Date of Notice	09/03/2026
ATTENTION:
The person for whose account the securities to which this notice relates are to be sold hereby represents by signing this notice that he does not know any material adverse information in regard to the current and prospective operations of the Issuer of the securities to be sold which has not been publicly disclosed. If such person has adopted a written trading plan or given trading instructions to satisfy Rule 10b5-1 under the Exchange Act, by signing the form and indicating the date that the plan was adopted or the instruction given, that person makes such representation as of the plan adoption or instruction date.
Signature	/s/ David Spetzler
ATTENTION: Intentional misstatements or omission of facts constitute Federal Criminal Violations (See 18 U.S.C. 1001)