Camp4 Therapeutics Schedule 13G/A: HarbourVest-affiliated entities report beneficial ownership of 1,271,948 shares of Camp4 common stock, representing 2.7% of the class. The shares are owned directly by SMRS-TOPE LLC, which holds sole voting and dispositive power over all 1,271,948 shares. HarbourVest Partners, LLC, HarbourVest Partners L.P. and HVST-TOPE LLC may be deemed to have shared voting and dispositive power but disclaim beneficial ownership. The filing includes a joint filing agreement among the reporting persons and is based on 46,842,126 shares outstanding used to calculate the 2.7% stake.
Positive
Transparency provided by timely Schedule 13G/A filing clarifies ownership structure and voting/dispositive powers
Non-controlling stake (2.7%) reduces near-term takeover or control concerns
Negative
None.
Insights
TL;DR: HarbourVest-linked entities disclosed a passive 2.7% stake, below the 5% threshold that typically triggers activist signaling.
The 2.7% position indicates a meaningful but non-controlling interest. Ownership is held directly by SMRS-TOPE LLC with sole voting and dispositive power, while parent entities disclaim direct beneficial ownership. For investors, this is a transparency filing rather than a change in control signal; no additional economic or strategic terms are reported.
TL;DR: This amendment clarifies ownership and control paths but shows no group intent to assert control or exercise activism.
The filing clarifies the ownership chain: HarbourVest entities are connected through manager/general partner relationships, but SMRS-TOPE LLC holds the actual shares and sole voting power. The disclaimers by HarbourVest entities are standard. There is no indication of coordinated group action, and the position size remains below thresholds that typically prompt governance changes.
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
SCHEDULE 13G
UNDER THE SECURITIES EXCHANGE ACT OF 1934
(Amendment No. 1)
CAMP4 Therapeutics Corporation
(Name of Issuer)
Common Stock, par value $0.0001 per share
(Title of Class of Securities)
13463J101
(CUSIP Number)
09/30/2025
(Date of Event Which Requires Filing of this Statement)
Check the appropriate box to designate the rule pursuant to which this Schedule is filed:
Rule 13d-1(b)
Rule 13d-1(c)
Rule 13d-1(d)
SCHEDULE 13G
CUSIP No.
13463J101
1
Names of Reporting Persons
HarbourVest Partners L.P.
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
1,271,948.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
1,271,948.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
1,271,948.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
2.7 %
12
Type of Reporting Person (See Instructions)
IA
SCHEDULE 13G
CUSIP No.
13463J101
1
Names of Reporting Persons
HarbourVest Partners, LLC
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
1,271,948.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
1,271,948.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
1,271,948.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
2.7 %
12
Type of Reporting Person (See Instructions)
IA
SCHEDULE 13G
CUSIP No.
13463J101
1
Names of Reporting Persons
SMRS-TOPE LLC
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
1,271,948.00
6
Shared Voting Power
0.00
7
Sole Dispositive Power
1,271,948.00
8
Shared Dispositive Power
0.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
1,271,948.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
2.7 %
12
Type of Reporting Person (See Instructions)
OO
SCHEDULE 13G
CUSIP No.
13463J101
1
Names of Reporting Persons
HVST-TOPE LLC
2
Check the appropriate box if a member of a Group (see instructions)
(a)
(b)
3
Sec Use Only
4
Citizenship or Place of Organization
DELAWARE
Number of Shares Beneficially Owned by Each Reporting Person With:
5
Sole Voting Power
0.00
6
Shared Voting Power
1,271,948.00
7
Sole Dispositive Power
0.00
8
Shared Dispositive Power
1,271,948.00
9
Aggregate Amount Beneficially Owned by Each Reporting Person
1,271,948.00
10
Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)
11
Percent of class represented by amount in row (9)
2.7 %
12
Type of Reporting Person (See Instructions)
OO
SCHEDULE 13G
Item 1.
(a)
Name of issuer:
CAMP4 Therapeutics Corporation
(b)
Address of issuer's principal executive offices:
One Kendall Square; Building 1400 West, 3rd Floor; Cambridge, MA 02139
Item 2.
(a)
Name of person filing:
HarbourVest Partners, LLC
HarbourVest Partners L.P.
HVST-TOPE LLC
SMRS-TOPE LLC
SMRS-TOPE LLC, HVST-TOPE LLC, HarbourVest Partners L.P. and HarbourVest Partners, LLC have entered into a Joint Filing Agreement, dated September [ ], 2025, a copy of which is filed with this Schedule 13G as Exhibit 99.1, pursuant to which such reporting persons agreed to file this statement and any amendments thereto jointly in accordance with the provisions of Rule 13d-1(k)(1) under the Securities Exchange Act of 1934, as amended.
(b)
Address or principal business office or, if none, residence:
The principal business office of each reporting person is One Lincoln Street, Suite 1700, Boston, MA 02111.
(c)
Citizenship:
Reporting entities are all organized and exist under the laws of the State of Delaware.
(d)
Title of class of securities:
Common Stock, par value $0.0001 per share
(e)
CUSIP No.:
13463J101
Item 3.
If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:
(a)
Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
(b)
Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
(c)
Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
(d)
Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
(e)
An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
(f)
An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
(g)
A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
(h)
A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
(i)
A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
(j)
A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J),
please specify the type of institution:
(k)
Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
Item 4.
Ownership
(a)
Amount beneficially owned:
Consists of 1,271,948 shares of common stock owned directly by SMRS-TOPE LLC. HarbourVest Partners, LLC ("HarbourVest") is the General Partner of HarbourVest Partners L.P., which is the Manager of HVST-TOPE LLC, which is the Managing Member of SMRS-TOPE LLC. Each of HarbourVest, HarbourVest Partners L.P. and HVST-TOPE LLC may be deemed to have a beneficial interest in the shares held by SMRS-TOPE LLC.
Voting and investment power over the securities owned directly by SMRS-TOPE LLC is exercised by the Investment Committee of HarbourVest. Each of HarbourVest, HarbourVest Partners L.P. and HVST-TOPE LLC and the members of the HarbourVest Investment Committee disclaim beneficial ownership of the shares held directly by SMRS-TOPE LLC.
(b)
Percent of class:
2.7% (based on 46,842,126 shares of common stock outstanding, which includes the 26,681,053 shares of common stock issued and sold to certain investors as reported in the Issuer's Current Report on Form 8-K, filed with the SEC on September 10, 2025 and the 20,161,073 shares of common stock outstanding as of August 5, 2025 as reported in the Issuer's Quarterly Report on Form 10-Q, filed with the SEC on August 14, 2025).
(c)
Number of shares as to which the person has:
(i) Sole power to vote or to direct the vote:
SMRS-TOPE LLC has the sole power to vote or to direct the vote of 1,271,948 shares of common stock.
(ii) Shared power to vote or to direct the vote:
HarbourVest, HarbourVest Partners L.P. and HVST-TOPE LLC may be deemed to have shared power to vote or direct the vote of 1,271,948 shares of common stock. Each of HarbourVest, HarbourVest Partners L.P. and HVST-TOPE LLC disclaim beneficial ownership of such shares.
(iii) Sole power to dispose or to direct the disposition of:
SMRS-TOPE LLC has the sole power to dispose or to direct the disposition of 1,271,948 shares of common stock.
(iv) Shared power to dispose or to direct the disposition of:
HarbourVest, HarbourVest Partners L.P. and HVST-TOPE LLC may be deemed to have shared power to dispose or direct the disposition of 1,271,948 shares of common stock. Each of HarbourVest, HarbourVest Partners L.P. and HVST-TOPE LLC disclaim beneficial ownership of such shares.
Item 5.
Ownership of 5 Percent or Less of a Class.
Ownership of 5 percent or less of a class
Item 6.
Ownership of more than 5 Percent on Behalf of Another Person.
If any other person is known to have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, such securities, a statement to that effect should be included in response to this item and, if such interest relates to more than 5 percent of the class, such person should be identified. A listing of the shareholders of an investment company registered under the Investment Company Act of 1940 or the beneficiaries of employee benefit plan, pension fund or endowment fund is not required.
See Item 4 above.
Item 7.
Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.
Not Applicable
Item 8.
Identification and Classification of Members of the Group.
Not Applicable
Item 9.
Notice of Dissolution of Group.
Not Applicable
Item 10.
Certifications:
Not Applicable
SIGNATURE
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.
HarbourVest Partners L.P.
Signature:
By: HarbourVest Partners, LLC, its General Partner; /s/ Adam Freedman
Name/Title:
Adam Freedman; Chief Compliance Officer
Date:
10/01/2025
HarbourVest Partners, LLC
Signature:
/s/ Adam Freedman
Name/Title:
Adam Freedman; Chief Compliance Officer
Date:
10/01/2025
SMRS-TOPE LLC
Signature:
By: HVST-TOPE LLC, its Managing Member; HarbourVest Partners L.P., its Manager; HarbourVest Partners, LLC, its General Partner; /s/ Adam Freedman
Name/Title:
Adam Freedman; Chief Compliance Officer
Date:
10/01/2025
HVST-TOPE LLC
Signature:
By: HarbourVest Partners L.P., its Manager; HarbourVest Partners, LLC, its General Partner; /s/ Adam Freedman
How many Camp4 (CAMP) shares do HarbourVest entities report owning?
They report beneficial ownership of 1,271,948 shares of Camp4 common stock.
What percent of CAMP does the reported stake represent?
The filing states the stake represents 2.7% of the outstanding common stock based on 46,842,126 shares.
Which entity holds the shares and who has voting power?
SMRS-TOPE LLC owns the shares directly and has sole voting and dispositive power over all 1,271,948 shares.
Do HarbourVest entities claim beneficial ownership of the shares?
HarbourVest Partners, LLC, HarbourVest Partners L.P. and HVST-TOPE LLC may be deemed to have shared power but they disclaim beneficial ownership in the filing.
Does this filing indicate an intent to acquire control of CAMP?
No. The disclosed 2.7% stake is below 5% and the filing contains no statements indicating a control intent.
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