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Carisma Therapeutics Inc SEC Filings

CARM NASDAQ

Welcome to our dedicated page for Carisma Therapeutics SEC filings (Ticker: CARM), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.

Decoding Carisma Therapeutics’ biotech disclosures can feel like reading advanced immunology. The company’s CAR-M pipeline, Moderna collaboration, and multi-indication studies load each 10-K and 10-Q with dense data on R&D burn, cGMP manufacturing, and trial risk factors. Even a one-page 8-K may hide a pivotal HER2 update investors cannot ignore.

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Rhea-AI Summary

Carisma Therapeutics (NASDAQ:CARM) has issued a Preliminary Proxy Statement for a virtual Special Meeting at an undisclosed 2025 date. Shareholders will vote on two items:

  • Proposal 1 – Reverse Stock Split: Authorizes the Board to implement a 1-for-10 to 1-for-50 reverse split at its discretion.
  • Proposal 2 – Adjournment: Permits adjournment if additional proxy solicitation time is required.

The reverse split is central to regaining Nasdaq listing compliance. Carisma is currently deficient under three rules: (i) Market Value of Listed Securities ($50 M), (ii) Market Value of Publicly Held Shares ($15 M) and (iii) Minimum Bid Price ($1.00). A Nasdaq Hearings Panel has granted an extension until October 7 2025; the company must post a ≥$1.00 bid for ten consecutive days and otherwise meet Capital Market standards during that period.

Management states the split is also a closing condition for the pending merger with Ocugen’s subsidiary OrthoCellix. Nasdaq rules require the combined entity to trade at ≥$4.00 per share before closing. Failure to approve the split could jeopardize both continued listing and the merger.

Only holders of record on a forthcoming record date may vote via internet, telephone, mail, or live during the virtual meeting. The proxy materials are available at www.investorvote.com/CARM.

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FAQ

What is the current stock price of Carisma Therapeutics (CARM)?

The current stock price of Carisma Therapeutics (CARM) is $0.4006 as of June 28, 2025.

What is the market cap of Carisma Therapeutics (CARM)?

The market cap of Carisma Therapeutics (CARM) is approximately 18.4M.

What is Carisma Therapeutics Inc.'s primary focus?

Carisma Therapeutics Inc. is focused on developing innovative immunotherapies using its proprietary cell engineering platform to create engineered macrophages and monocytes for treating cancer, fibrosis, and autoimmune diseases.

How does the CAR-M platform work?

The CAR-M platform involves reprogramming macrophages and monocytes ex vivo and in vivo to enhance their natural immune functions, increasing their ability to infiltrate tumors or fibrotic tissues and deliver therapeutic effects.

In which therapeutic areas does Carisma operate?

Carisma pursues treatments in oncology, particularly for HER2-positive solid tumors, as well as targets in liver fibrosis and autoimmune diseases, leveraging its engineered cell therapy platform.

What distinguishes Carisma's approach from other cell therapies?

Unlike many therapies that rely on T-cell engineering, Carisma focuses on myeloid cells, such as macrophages and monocytes, which play key roles in both innate and adaptive immunity, allowing for potentially enhanced tissue infiltration and scalability.

What role do strategic collaborations play in Carisma’s business model?

Carisma collaborates with established biotech partners, including Moderna, to combine its CAR-M technology with complementary platforms like mRNA/LNP delivery systems, thereby accelerating the development and potential impact of its cell therapies.

How is Carisma addressing challenges in solid tumor treatment?

Carisma’s engineered cell therapies are designed to overcome issues such as tumor microenvironment immunosuppression, poor cell persistence, and antigen heterogeneity through enhanced cell infiltration and targeted therapeutic payloads.

What recent strategic changes have been implemented by Carisma Therapeutics?

Carisma has recently reprioritized its pipeline, redirecting resources toward its most promising programs in in vivo macrophage engineering, specifically targeting oncology, fibrosis, and autoimmune areas, while streamlining operations.

What benefits do engineered macrophages offer in liver fibrosis treatment?

Engineered macrophages can modulate key pathological pathways in liver fibrosis, such as reducing stellate cell activation and promoting tissue repair, offering a novel, off-the-shelf approach to address advanced fibrotic liver diseases.
Carisma Therapeutics Inc

NASDAQ:CARM

CARM Rankings

CARM Stock Data

18.43M
30.19M
30.93%
30.13%
1.11%
Biotechnology
Pharmaceutical Preparations
Link
United States
PHILADELPHIA