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RA Capital lifts Climb Bio (CLYM) stake with $20M PIPE warrants

Filing Impact
(Moderate)
Filing Sentiment
(Neutral)
Form Type
SCHEDULE 13D/A

Rhea-AI Filing Summary

RA Capital Management and affiliates report a significant position in Climb Bio, Inc., beneficially owning 22,631,401 shares of common stock, or 33.0% of the class. The stake includes common shares, stock options and pre-funded warrants that are exercisable within 60 days, subject to ownership limits.

The filing details an April 2026 private placement in which Climb Bio issued 9,481,000 common shares at $9.50 per share and 2,106,000 pre-funded warrants at $9.4999 each. RA Capital’s fund purchased all 2,106,000 pre-funded warrants for $20,006,789.40, funded from its working capital.

The pre-funded warrants are exercisable at $0.0001 per share and do not expire, but a 33.0% beneficial ownership blocker restricts further exercise above that threshold. Climb Bio agreed to register for resale both the private placement shares and the warrant shares under a registration rights agreement that includes filing deadlines, effectiveness requirements and potential liquidated damages.

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Insights

RA Capital now reports a 33% beneficial stake in Climb Bio, anchored by a recent $20M PIPE purchase.

The filing shows RA Capital and related funds beneficially owning 22,631,401 Climb Bio shares, or 33.0% of the common stock, combining common shares, options and pre-funded warrants. This reflects a concentrated institutional position with delegated voting and investment authority managed by RA Capital.

The April 2026 private placement added 9,481,000 new shares at $9.50 and 2,106,000 pre-funded warrants at $9.4999. The Fund bought all 2,106,000 warrants for total consideration of $20,006,789.40, while the warrants carry a token $0.0001 exercise price and no expiration.

A key structural feature is the beneficial ownership blocker that caps warrant exercises if ownership would exceed 33.0%. This limits further equity accumulation via these instruments. Additionally, a registration rights agreement obligates Climb Bio to register the PIPE shares and warrant shares within 45 days of closing, with potential liquidated damages if deadlines tied to the April 2026 placement are missed.

Beneficial ownership 22,631,401 shares Shares of Climb Bio common stock beneficially owned by RA Capital reporting group
Ownership percentage 33.0% of class Percent of Climb Bio common stock represented by 22,631,401 shares
Fund ownership 17,123,763 shares (25.0%) Climb Bio shares beneficially owned by RA Capital Healthcare Fund, L.P.
Nexus Fund III ownership 5,346,247 shares (9.3%) Climb Bio shares beneficially owned by RA Capital Nexus Fund III, L.P.
Sera Medicines stake 2,479,872 shares (4.3%) Climb Bio shares beneficially owned by Sera Medicines, LLC
PIPE common shares 9,481,000 shares at $9.50 Common stock issued in April 2026 private placement
Pre-funded warrants 2,106,000 at $9.4999 April 2026 pre-funded warrants issued in the private placement
PIPE consideration $20,006,789.40 Total paid by the Fund for 2,106,000 April 2026 pre-funded warrants
Pre-Funded Warrants financial
"pre-funded warrants (the "Pre-Funded Warrants") exercisable for up to 22,546,000 shares of common stock"
Pre-funded warrants are financial instruments that give investors the right to purchase a company's stock at a set price, but with most or all of the purchase price paid upfront. They function like a coupon or gift card for stock, allowing investors to buy shares later at a fixed price, which can be beneficial if they want to avoid future price increases. This makes them important for investors seeking flexibility and certainty in their investment plans.
Beneficial Ownership Blocker financial
"The Pre-Funded Warrants contain a provision (the "Beneficial Ownership Blocker") which precludes exercise"
Registration Rights Agreement financial
"the Issuer has entered into a registration rights agreement (the "April 2026 Registration Rights Agreement")"
A registration rights agreement is a contract that gives investors the option to have their ownership stakes officially registered with the government, making it easier to sell their shares later. This agreement matters because it provides investors with a clearer path to cash out their investments if they choose, offering more liquidity and confidence in their ability to sell their holdings when desired.
Rule 144 regulatory
"without regard to any volume or manner-of-sale limitations by reason of Rule 144 under the Securities Act"
Rule 144 is a U.S. securities regulation that sets conditions under which restricted or insider-held shares can be legally resold to the public, such as required holding periods, availability of public information, limits on how much can be sold at once, and certain filing requirements. For investors it matters because it determines when previously locked-up shares can enter the market — like a release valve that can increase supply, affect share price, and signal insider intent.
Schedule 13(d) regulatory
"for purposes of Section 13(d) of the Securities Exchange Act of 1934"
PIPE Investors financial
"with certain institutional accredited investors (the "April 2026 PIPE Investors"), including the Fund"
Pipe investors are private buyers—such as institutional funds, hedge funds, or accredited individuals—who purchase shares or convertible securities directly from a publicly traded company in a private placement. They matter because this type of transaction quickly brings the company cash but can dilute existing shareholders and signal management’s view of financing needs; think of it like a private cash infusion that can stabilize operations but changes ownership stakes and future share value.





28658R106

(CUSIP Number)
Peter Kolchinsky
RA Capital Management, L.P., 200 Berkeley Street, 18th Floor
Boston, MA, 02116
617.778.2500

(Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications)
04/27/2026

(Date of Event Which Requires Filing of This Statement)


If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§ 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box.

The information required on the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).




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SCHEDULE 13D






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SCHEDULE 13D


RA Capital Management, L.P.
Signature:/s/ Peter Kolchinsky
Name/Title:By Peter Kolchinsky, Authorized Signatory
Date:04/29/2026
Peter Kolchinsky
Signature:/s/ Peter Kolchinsky
Name/Title:Peter Kolchinsky
Date:04/29/2026
Rajeev Shah
Signature:/s/ Rajeev Shah
Name/Title:Rajeev Shah
Date:04/29/2026
RA Capital Healthcare Fund, L.P.
Signature:/s/ Peter Kolchinsky
Name/Title:By RA Capital Healthcare Fund GP, LLC, its General Partner, By Peter Kolchinsky, Manager
Date:04/29/2026
RA Capital Nexus Fund III, L.P.
Signature:/s/ Peter Kolchinsky
Name/Title:By RA Capital Nexus Fund III GP, LLC, its General Partner, By Peter Kolchinsky, Manager
Date:04/29/2026
Sera Medicines, LLC
Signature:/s/ Stephen Thomas
Name/Title:By Stephen Thomas, Chief Executive Officer
Date:04/29/2026

FAQ

What stake in Climb Bio (CLYM) does RA Capital report in this Schedule 13D/A?

RA Capital Management and affiliates report beneficial ownership of 22,631,401 Climb Bio common shares, representing 33.0% of the class. This figure includes common stock, pre-funded warrants and stock options that are exercisable within 60 days, based on the share count framework described.

What are the key terms of Climb Bio (CLYM)’s April 2026 private placement?

Climb Bio issued 9,481,000 common shares at $9.50 per share and 2,106,000 pre-funded warrants at $9.4999 each in an April 2026 private placement. The transaction closed on April 29, 2026 and involved certain institutional accredited investors, including RA Capital’s fund.

How much did RA Capital invest in Climb Bio (CLYM) pre-funded warrants?

RA Capital’s fund purchased 2,106,000 April 2026 pre-funded warrants for total consideration of $20,006,789.40. The purchase price per warrant was $9.4999, funded from the fund’s working capital, and each warrant is exercisable into one Climb Bio common share at a $0.0001 exercise price.

What is the 33.0% beneficial ownership blocker mentioned for Climb Bio (CLYM)?

The pre-funded warrants include a 33.0% beneficial ownership blocker that prevents the fund from exercising warrants if, after exercise, it and its affiliates would own more than 33.0% of Climb Bio’s outstanding common stock. This provision limits additional equity accumulation through these warrants.

What registration rights did Climb Bio (CLYM) grant PIPE investors in April 2026?

Climb Bio agreed to register for resale the April 2026 PIPE shares and warrant shares under a registration rights agreement. The company must file a resale registration statement within 45 days of closing, use reasonable best efforts to obtain effectiveness, and may owe liquidated damages if deadlines are missed.

Why did Sera Medicines, LLC fall below 5% ownership of Climb Bio (CLYM)?

Sera Medicines, LLC ceased to be a beneficial owner of more than 5% of Climb Bio’s common stock on April 29, 2026. This resulted from dilution caused by the closing of the April 2026 private placement, which increased the company’s total outstanding common shares.