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Cardiol Therapeutics (NASDAQ: CRDL) outlines heart programs at TD Cowen

Filing Impact
(Neutral)
Filing Sentiment
(Neutral)
Form Type
6-K

Rhea-AI Filing Summary

Cardiol Therapeutics Inc. filed a Form 6-K highlighting its upcoming presentation at the TD Cowen 46th Annual Health Care Conference in Boston. Company management will present on March 4, 2026, at 10:30 a.m. EST, with a live and replay webcast available in the Investors section of its website.

The filing also outlines Cardiol’s late-stage pipeline. Lead candidate CardiolRx™ targets inflammasome pathway activation in heart diseases such as recurrent pericarditis, acute myocarditis, and heart failure. Cardiol has completed Phase II studies in recurrent pericarditis and acute myocarditis and is conducting a pivotal Phase III trial in recurrent pericarditis, which has U.S. FDA Orphan Drug Designation.

Cardiol is additionally developing CRD-38, a novel subcutaneous formulation for inflammatory heart disease, including heart failure, a major cause of death and hospitalization with U.S. healthcare costs noted as exceeding US$30 billion per year.

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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

FORM 6-K

REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16
UNDER THE SECURITIES EXCHANGE ACT OF 1934

For the month of February 2026

Commission File Number: 001-40712

Cardiol Therapeutics Inc.
(Translation of registrant's name into English)

602-2265 Upper Middle Road East, Oakville, Ontario, Canada L6H 0G5
(Address of principal executive offices)

Indicate by check mark whether the registrant files or will file annual reports under cover Form 20-F or Form 40-F.

[   ] Form 20-F     [X] Form 40-F


SUBMITTED HEREWITH

Exhibits

Exhibit   Description
   
99.1   News Release dated February 25, 2026 - Cardiol Therapeutics to Present at TD Cowen 46th Annual Health Care Conference


SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

  CARDIOL THERAPEUTICS INC.
  (Registrant)
     
Date: February 25, 2026 By: /s/ Chris Waddick
   
    Chris Waddick
  Title: Chief Financial Officer



Cardiol Therapeutics to Present at TD Cowen 46th Annual Health Care
Conference

Toronto, ON - February 25, 2026 - Cardiol Therapeutics Inc. (NASDAQ: CRDL) (TSX: CRDL) ("Cardiol" or the "Company"), a late-stage life sciences company focused on advancing the development of anti-inflammatory and anti-fibrotic therapies for heart disease, is pleased to announce that it will participate at the upcoming TD Cowen 46th Annual Health Care Conference in Boston, MA. Members of management will present on March 4, 2026, at 10:30 a.m. EST.

A live webcast of the Company's presentation, as well as a webcast replay will be available under "Events & Presentations" in the Investors section of the Cardiol website (www.cardiolrx.com/investors/events-presentations/).

About Cardiol Therapeutics

Cardiol Therapeutics Inc. (NASDAQ: CRDL) (TSX: CRDL) is a late-stage life sciences company focused on advancing the development of anti-inflammatory and anti-fibrotic therapies for heart disease. The Company's lead small-molecule drug candidate, CardiolRx™, modulates inflammasome pathway activation, an intracellular process known to play an important role in the development and progression of inflammation and fibrosis associated with pericarditis, myocarditis, and heart failure.

The MAVERIC Program is evaluating CardiolRx™ for the treatment of recurrent pericarditis, an inflammatory disease of the pericardium associated with symptoms including debilitating chest pain, shortness of breath, and fatigue, which can lead to physical limitations, reduced quality of life, emergency department visits, and hospitalizations. The program comprises the completed Phase II MAvERIC-Pilot study (NCT05494788) and the ongoing pivotal Phase III MAVERIC trial (NCT06708299). The U.S. FDA has granted Orphan Drug Designation to CardiolRx™ for the treatment of pericarditis, including recurrent pericarditis.

The ARCHER Program is also studying CardiolRx™, specifically in acute myocarditis-an important cause of acute and fulminant heart failure in young adults and a leading cause of sudden cardiac death in individuals under 35 years of age. The program comprises the completed Phase II ARCHER study (NCT05180240), which evaluated the safety, tolerability, and efficacy of CardiolRx™ in this patient population.

The Company is also developing CRD-38, a novel, subcutaneously administered drug formulation intended for the treatment of inflammatory heart disease, including heart failure-a leading cause of death and hospitalization in the developed world, with associated healthcare costs in the United States exceeding US$30 billion per year.

For more information about Cardiol Therapeutics, please visit cardiolrx.com.

Cautionary statement regarding forward-looking information:

This news release contains "forward-looking information" within the meaning of applicable securities laws. All statements, other than statements of historical fact, that address activities, events, or developments that Cardiol believes, expects, or anticipates will, may, could, or might occur in the future are "forward-looking information". Forward-looking information contained herein may include, but is not limited to statements regarding the Company's focus on developing anti-inflammatory and anti-fibrotic therapies for the treatment of heart disease, the Company's intended clinical studies and trial activities and timelines associated with such activities, including the Company's plan to complete the Phase III study in recurrent pericarditis with CardiolRx™, and the Company's plan to advance the development of CRD-38, a novel subcutaneous formulation intended for the treatment of inflammatory heart disease, including heart failure, including through the initiation of the first-in-human clinical evaluation. Forward-looking information contained herein reflects the current expectations or beliefs of Cardiol based on information currently available to it and is based on certain assumptions and is also subject to a variety of known and unknown risks and uncertainties and other factors that could cause the actual events or results to differ materially from any future results, performance or achievements expressed or implied by the forward-looking information, and are not (and should not be considered to be) guarantees of future performance. These risks and uncertainties and other factors include the risks and uncertainties referred to in the Company's Annual Information Form filed with the Canadian securities administrators and U.S. Securities and Exchange Commission on March 31, 2025, available on SEDAR+ at sedarplus.ca and EDGAR at sec.gov, as well as the risks and uncertainties associated with product commercialization and clinical studies. These assumptions, risks, uncertainties, and other factors should be considered carefully, and investors should not place undue reliance on the forward-looking information, and such information may not be appropriate for other purposes. Any forward-looking information speaks only as of the date of this press release and, except as may be required by applicable securities laws, Cardiol disclaims any intent or obligation to update or revise such forward-looking information, whether as a result of new information, future events, or results, or otherwise. Investors are cautioned not to rely on these forward-looking statements.


For further information, please contact:

Investor.relations@cardiolrx.com


FAQ

What did Cardiol Therapeutics (CRDL) disclose in its February 2026 Form 6-K?

Cardiol Therapeutics reported that management will present at the TD Cowen 46th Annual Health Care Conference on March 4, 2026. The company also summarized its late-stage cardiovascular pipeline, including CardiolRx™ programs in recurrent pericarditis and acute myocarditis, and development of its subcutaneous candidate CRD-38.

When and where will Cardiol Therapeutics present at the TD Cowen Health Care Conference?

Cardiol Therapeutics management will present on March 4, 2026, at 10:30 a.m. EST at the TD Cowen 46th Annual Health Care Conference in Boston. A live webcast and replay of the presentation will be accessible through the Investors “Events & Presentations” section of the company’s website.

What is CardiolRx and which heart conditions is Cardiol Therapeutics targeting?

CardiolRx™ is Cardiol Therapeutics’ lead small-molecule drug candidate that modulates inflammasome pathway activation. The company is evaluating it for recurrent pericarditis and acute myocarditis, conditions linked to inflammation and fibrosis that can cause debilitating chest pain, heart failure in young adults, and increased hospitalization risk.

What clinical programs are included in Cardiol Therapeutics’ MAVERIC Program?

The MAVERIC Program evaluates CardiolRx™ for recurrent pericarditis and includes the completed Phase II MAvERIC-Pilot study (NCT05494788) and the ongoing pivotal Phase III MAVERIC trial (NCT06708299). The U.S. FDA has granted Orphan Drug Designation to CardiolRx™ for treating pericarditis, including recurrent pericarditis.

What did Cardiol Therapeutics disclose about the ARCHER Program in myocarditis?

The ARCHER Program studies CardiolRx™ in acute myocarditis, an important cause of acute and fulminant heart failure in young adults and a leading cause of sudden cardiac death under age 35. Cardiol completed the Phase II ARCHER study (NCT05180240) assessing safety, tolerability, and efficacy in this population.

What is CRD-38 and how is Cardiol Therapeutics positioning this drug candidate?

CRD-38 is a novel, subcutaneously administered drug formulation being developed for inflammatory heart disease, including heart failure. Cardiol plans to advance CRD-38 through first-in-human clinical evaluation, targeting conditions that contribute to U.S. heart failure healthcare costs exceeding US$30 billion annually, as described in the disclosure.

What forward-looking statements did Cardiol Therapeutics include in this disclosure?

Cardiol included forward-looking information about its focus on anti-inflammatory and anti-fibrotic heart disease therapies, plans to complete the Phase III recurrent pericarditis study with CardiolRx™, and intentions to advance CRD-38 into first-in-human evaluation, while cautioning these plans are subject to assumptions, risks, and uncertainties detailed in its filings.

Filing Exhibits & Attachments

1 document