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Crinetics Pharmaceuticals (CRNX) elevates Jeff Knight to development and operating role

Filing Impact
(High)
Filing Sentiment
(Neutral)
Form Type
8-K

Rhea-AI Filing Summary

Crinetics Pharmaceuticals, Inc. reported a leadership title change for one of its senior executives. Effective January 2, 2026, Jeff Knight’s role was updated from Chief Operating Officer to Chief Development and Operating Officer. The board of directors approved this change on January 20, 2026, to better reflect his existing responsibilities and scope of duties.

The company stated that there were no changes to Mr. Knight’s compensation arrangements in connection with this new title. Crinetics also confirmed that there are no arrangements or understandings with any other person related to his selection for this role, no family relationships with any director or executive officer, and no reportable related party transactions involving him. His business experience is described in the company’s 2025 proxy statement, which is incorporated by reference.

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0001658247false00016582472026-01-262026-01-26

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549
_________________________________________________________
FORM 8-K
_________________________________________________________
CURRENT REPORT
Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934
Date of Report (Date of earliest event reported): January 20, 2026
_________________________________________________________
Crinetics Pharmaceuticals, Inc.
(Exact name of Registrant as Specified in Its Charter)
_________________________________________________________
Delaware001-3858326-3744114
(State or Other Jurisdiction
of Incorporation)
(Commission File Number)(IRS Employer
Identification No.)
6055 Lusk Boulevard
San Diego, California
92121
(Address of Principal Executive Offices)(Zip Code)
Registrant’s Telephone Number, Including Area Code: (858) 450-6464
(Former Name or Former Address, if Changed Since Last Report)
_________________________________________________________
Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the registrant under any of the following provisions:
o    Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)
o    Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)
o    Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))
o    Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act (17 CFR 240.13e-4(c))
Securities registered pursuant to Section 12(b) of the Act:
Title of each classTrading
Symbol(s)
Name of each exchange on which registered
Common Stock, par value $0.001 per shareCRNXNasdaq Global Select Market
Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of 1933 (§ 230.405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (§ 240.12b-2 of this chapter).
Emerging growth company o
If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. o



Item 5.02 Departure of Directors or Certain Officers; Election of Directors, Appointment of Certain Officers; Compensatory Arrangements of Certain Officers.
On January 20, 2026, the board of directors of Crinetics Pharmaceuticals, Inc. (the “Company”) approved a change in title and responsibilities for Jeff Knight, from Chief Operating Officer to Chief Development and Operating Officer, effective January 2, 2026.
The change in title reflects Mr. Knight's responsibilities and scope of duties.
There were no changes to Mr. Knights's compensation arrangements, as described in the Company's definitive proxy statement on Schedule 14A filed with the Securities and Exchange Commission on April 23, 2025 (the "2025 Proxy Statement"), in connection with this title change. There are no arrangements or understandings between Mr. Knight and any other person pursuant to which he was selected as Chief Development and Operating Officer, there are no family relationships between Mr. Knight and any director or executive officer of the Company, and there are no reportable family relationships or related party transactions (as defined in Item 404(a) of Regulation S-K) involving Mr. Knight and the Company. A description of Mr. Knight's business experience is contained in the 2025 Proxy Statement, which description is incorporated herein by reference.
Item 9.01     Financial Statements and Exhibits.
(d)Exhibits
Exhibit No.Description
104Cover Page Interactive Data File (embedded within the Inline XBRL document)



SIGNATURES
Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.
Crinetics Pharmaceuticals, Inc.
Date:
January 26, 2026
By:/s/ R. Scott Struthers, Ph.D.
R. Scott Struthers, Ph.D.
President and Chief Executive Officer
(Principal Executive Officer)

FAQ

What executive change did Crinetics Pharmaceuticals (CRNX) disclose in this 8-K?

Crinetics Pharmaceuticals disclosed that Jeff Knight’s title was changed from Chief Operating Officer to Chief Development and Operating Officer, effective January 2, 2026.

Did Jeff Knight’s compensation change with his new role at Crinetics Pharmaceuticals (CRNX)?

No. The company stated there were no changes to Mr. Knight’s compensation arrangements in connection with his new title.

When did the Crinetics Pharmaceuticals (CRNX) board approve Jeff Knight’s new title?

The board of directors approved Jeff Knight’s title change on January 20, 2026.

Are there any family or related party relationships involving Jeff Knight at Crinetics Pharmaceuticals (CRNX)?

The company reported no family relationships between Jeff Knight and any director or executive officer and no reportable related party transactions involving him.

Where can investors find more background on Jeff Knight’s experience at Crinetics Pharmaceuticals (CRNX)?

A description of Jeff Knight’s business experience is included in the company’s 2025 proxy statement on Schedule 14A, which is incorporated by reference.
Crinetics Pharmaceuticals

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Biotechnology
Pharmaceutical Preparations
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United States
SAN DIEGO