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Crinetics Pharmaceuticals SEC Filings

CRNX NASDAQ

Welcome to our dedicated page for Crinetics Pharmaceuticals SEC filings (Ticker: CRNX), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.

Parsing a biotech 10-K crammed with receptor pharmacology, clinical trial endpoints, and R&D burn rates can feel impossible. Crinetics Pharmaceuticals’ disclosures are especially dense because every milestone for paltusotine and atumelnant must be documented in detail. If you have ever wondered, “Where do I find Crinetics Pharmaceuticals insider trading Form 4 transactions before the market reacts?” or “How do I extract trial-stage spending from their quarterly earnings report 10-Q filing?”, you are in the right place.

Stock Titan applies AI-powered summaries to every Crinetics filing—turning 250-page documents into clear takeaways in seconds. Get real-time alerts the moment a Crinetics Pharmaceuticals Form 4 insider transactions real-time update hits EDGAR. Drill into each Crinetics Pharmaceuticals annual report 10-K simplified for R&D cost trends, or scan a Crinetics Pharmaceuticals proxy statement executive compensation to see how stock awards align with endocrine-drug milestones. Our coverage spans all forms: 8-K material events explained (trial data releases or FDA designations), S-3 capital raises, definitive proxies, plus every Crinetics Pharmaceuticals quarterly earnings report 10-Q filing with side-by-side earnings report filing analysis.

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Rhea-AI Summary

Crinetics Pharmaceuticals (Nasdaq:CRNX) furnished an 8-K covering its June 26 2025 R&D Day. Management unveiled new pre-clinical data on three assets—TSHR antagonist CRN12755 for Graves’ disease, SST3 agonist CRN10329 for ADPKD and drug-conjugate CRN09682 for SST2-positive tumors—and outlined the Phase 1/2 BRAVESST2 design enrolling up to 150 patients. Highlights include reductions in thyroid hormone, hyaluronic acid, IL-6 and cystic indices, plus dose-dependent anti-tumor activity. No financial results or guidance were provided; information is “furnished,” not “filed,” and forward-looking statements stress clinical, regulatory and financing risks.

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FAQ

What is the current stock price of Crinetics Pharmaceuticals (CRNX)?

The current stock price of Crinetics Pharmaceuticals (CRNX) is $29.96 as of June 28, 2025.

What is the market cap of Crinetics Pharmaceuticals (CRNX)?

The market cap of Crinetics Pharmaceuticals (CRNX) is approximately 2.8B.

What is the primary focus of Crinetics Pharmaceuticals?

Crinetics Pharmaceuticals focuses on the discovery, development, and commercialization of novel, orally delivered therapeutics for endocrine diseases and endocrine-related tumors.

Which key conditions are targeted by Crinetics' drug candidates?

Their drug candidates primarily target conditions such as acromegaly, carcinoid syndrome, congenital adrenal hyperplasia, and ACTH-dependent Cushing’s syndrome.

What makes paltusotine unique as a therapeutic agent?

Paltusotine is a first-in-class, once-daily, oral nonpeptide agonist that selectively targets somatostatin receptor type 2 (SST2), aiming to provide a convenient alternative to injectable therapies.

How does atumelnant differ from traditional treatments?

Atumelnant is designed as an oral ACTH receptor antagonist that targets the melanocortin type 2 receptor (MC2R) to achieve rapid and sustained control of key biomarkers in conditions like congenital adrenal hyperplasia and Cushing’s syndrome.

What is the advantage of oral small molecule therapeutics?

Oral small molecule therapeutics offer ease of administration, improved patient adherence, and potentially reduced treatment burden compared to traditional injectable therapies.

How does Crinetics demonstrate its expertise in drug discovery?

Crinetics employs a robust in-house discovery engine to design and develop new chemical entities, integrating advanced receptor targeting strategies with comprehensive clinical evaluation.

What are the key competitive advantages of Crinetics Pharmaceuticals?

Their competitive advantages include innovative oral formulations, targeted receptor modulation, a diverse clinical pipeline, and a strategic approach that focuses on unmet needs in rare endocrine disorders.

Which market segments does Crinetics serve?

Crinetics serves niche market segments within endocrinology, particularly focusing on rare endocrine diseases and related tumors where traditional therapeutic approaches have limitations.
Crinetics Pharmaceuticals

NASDAQ:CRNX

CRNX Rankings

CRNX Stock Data

2.80B
90.79M
2.09%
110.85%
8.71%
Biotechnology
Pharmaceutical Preparations
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United States
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