STOCK TITAN

[Form 4] Crinetics Pharmaceuticals, Inc. Insider Trading Activity

Filing Impact
(Neutral)
Filing Sentiment
(Negative)
Form Type
4

Crinetics Pharmaceuticals (CRNX) reporting person Dana Pizzuti executed option exercises and open-market sales on 10/01/2025. The Form 4 shows a stock option exercise for 5,000 shares at an exercise price of $16.89, creating 5,000 underlying shares. The same day, 5,000 shares were sold in open-market transactions under a Rule 10b5-1 trading plan at a volume-weighted average price of $41.81 (range $41.34–$42.16). Following the reported transactions, the reporting person directly owned 66,270 shares. The filer corrected a prior Form 4 that had misstated post-transaction ownership as 96,270 shares; the correction clarifies the true direct ownership.

Crinetics Pharmaceuticals (CRNX) persona di segnalazione Dana Pizzuti ha eseguito esercizi di opzioni e vendite in mercato aperto il 10/01/2025. Il Modulo 4 mostra un esercizio di opzione su azioni per 5.000 titoli a un prezzo di esercizio di $16,89, generando 5.000 azioni sottostanti. Nello stesso giorno, 5.000 azioni sono state vendute in operazioni di mercato aperto nell'ambito di un piano di trading Rule 10b5-1 a un prezzo medio ponderato per volume di $41,81 (intervallo $41,34–$42,16). A seguito delle transazioni riportate, la persona di segnalazione deteneva direttamente 66.270 azioni. Il compilatore ha corretto un precedente Form 4 che aveva dichiarato erroneamente la proprietà post-transazione come 96.270 azioni; la correzione chiarisce la reale proprietà diretta.

Crinetics Pharmaceuticals (CRNX) persona reportante Dana Pizzuti ejecutó ejercicios de opciones y ventas en el mercado abierto el 10/01/2025. El Formulario 4 muestra un ejercicio de opción sobre acciones de 5,000 a un precio de ejercicio de $16.89, creando 5.000 acciones subyacentes. Ese mismo día, se vendieron 5.000 acciones en transacciones de mercado abierto bajo un plan de negociación Rule 10b5-1 con un precio medio ponderado por volumen de $41.81 (rango $41.34–$42.16). Tras las transacciones reportadas, la persona reportante poseía directamente 66,270 acciones. El presentador corrigió un Formulario 4 anterior que había indicado incorrectamente la propiedad posterior a la transacción como 96.270 acciones; la corrección aclara la verdadera propiedad directa.

Crinetics Pharmaceuticals (CRNX) 보고인 다나 피줄리이 옵션 행사와 공개시장 매도을 2025-10-01에 실행했습니다. 양식 4는 5,000주에 대한 주식 옵션 행사를 행사 가격 $16.89로 보여 주며 5,000주가 기초 주식으로 만들어집니다. 같은 날, 5,000주가 매도되었으며, 규칙 10b5-1 거래 계획에 따라 거래량 가중 평균가 $41.81로 이루어졌고 범위는 $41.34–$42.16입니다. 보고된 거래 이후 보고인은 직접적으로 66,270주를 보유했습니다. 보고인은 거래 후 소유를 96,270주로 잘못 기재한 이전 Form 4를 수정했으며, 수정은 진정한 직접 소유를 명확히 합니다.

Crinetics Pharmaceuticals (CRNX) personne rapportante Dana Pizzuti a exécuté des exercices d’options et des ventes sur le marché libre le 10/01/2025. Le Formulaire 4 affiche un exercice d’options d’actions sur 5 000 titres à un prix d’exercice de $16,89, créant 5 000 actions sous-jacentes. Le même jour, 5 000 actions ont été vendues dans des transactions sur le marché libre dans le cadre d’un plan de négociation Rule 10b5-1 à un prix moyen pondéré en fonction du volume de $41,81 (plage $41,34–$42,16). À la suite des transactions rapportées, la personne rapportante détenait directement 66 270 actions. Le déclarant a corrigé un Formulaire 4 antérieur qui avait indiqué à tort une propriété post-transaction de 96 270 actions; la correction précise la véritable propriété directe.

Crinetics Pharmaceuticals (CRNX) meldende Person Dana Pizzuti hat Optionsausübungen und Verkäufe am freien Markt am 10/01/2025 durchgeführt. Das Formular 4 zeigt eine Ausübung einer Aktienoption über 5.000 Stück zu einem Ausübungspreis von $16,89, wodurch 5.000 zugrunde liegende Aktien geschaffen werden. Am selben Tag wurden 5.000 Aktien in freien Markttransaktionen unter einem Handelsplan nach Regel 10b5-1 zu einem volumenindizierten Durchschnittspreis von $41,81 (Spanne $41,34–$42,16) verkauft. Nach den gemeldeten Transaktionen hielt die meldende Person direkt 66.270 Aktien. Der Einreicher korrigierte ein vorheriges Form 4, das den Besitz nach der Transaktion fälschlicherweise mit 96.270 Aktien angegeben hatte; die Korrektur klärt den tatsächlichen direkten Besitz auf.

شركة Crinetics Pharmaceuticals (CRNX) كشفت الشخص المبلغ دانا بيتسوتي عن تنفيذ تمارين خيارات ومبيعات في السوق المفتوح في 10/01/2025. يظهر النموذج 4 تمرين خيار أسهم لـ 5,000 سهم بسعر تنفيذ $16.89، مما أوجد 5,000 سهم أساسي. في اليوم نفسه، تم بيع 5,000 سهم في معاملات السوق المفتوح بموجب خطة تداول القاعدة 10b5-1 عند سعر متوسط وزني حجمي قدره $41.81 (نطاق $41.34–$42.16). عقب المعاملات المبلغ عنها، امتلك الشخص المبلغ مباشرة 66,270 سهمًا. صحح المقدم نموذج Form 4 سابقًا والذي كان قد ذكر الملكية بعد الصفقة بمقدار 96,270 سهمًا؛ التعديل يوضح الملكية المباشرة الصحيحة.

Crinetics Pharmaceuticals (CRNX) 报告人 Dana Pizzuti2025/10/01 执行了期权行使和在公开市场的出售。 Form 4 显示 5,000 股的股票期权行使,行使价为 $16,89,产生了 5,000 股基础股。 同日,在公开市场交易中以规则 10b5-1 计划进行的交易出售了 5,000 股,成交量加权平均价为 $41,81(区间 $41,34–$42,16)。在报告的交易之后,报告人直接拥有 66,270 股。 申报人纠正了一个先前的 Form 4,该表述的交易后持股为 96,270 股的说法;该更正澄清了真实的直接所有权。

Positive
  • Adopted Rule 10b5-1 plan execution for the sale on 10/01/2025, indicating pre-planned transactions
  • Option exercise of 5,000 shares at $16.89, establishing shares without relying solely on open-market purchases
Negative
  • Correction to prior Form 4 required: prior filing misstated post-transaction ownership as 96,270 instead of 66,270
  • Sale of 5,000 shares reduced direct holdings to 66,270, a disclosure investors may view as insider liquidity

Insights

Insider exercised options and sold an equal number of shares under a Rule 10b5-1 plan on 10/01/2025.

The reporting person exercised a 5,000-share option at $16.89, creating immediate beneficial ownership and then sold 5,000 shares in open-market trades at a $41.81 VWAP under a pre-existing Rule 10b5-1 plan. This sequence (exercise then sale) is a routine liquidity event where proceeds likely exceed the exercise cost on the disclosed prices.

The filing also corrects an earlier reporting error that overstated post-transaction ownership as 96,270 shares; the corrected post-transaction direct holding is 66,270 shares, which is important for accurate insider ownership records and disclosure compliance.

Crinetics Pharmaceuticals (CRNX) persona di segnalazione Dana Pizzuti ha eseguito esercizi di opzioni e vendite in mercato aperto il 10/01/2025. Il Modulo 4 mostra un esercizio di opzione su azioni per 5.000 titoli a un prezzo di esercizio di $16,89, generando 5.000 azioni sottostanti. Nello stesso giorno, 5.000 azioni sono state vendute in operazioni di mercato aperto nell'ambito di un piano di trading Rule 10b5-1 a un prezzo medio ponderato per volume di $41,81 (intervallo $41,34–$42,16). A seguito delle transazioni riportate, la persona di segnalazione deteneva direttamente 66.270 azioni. Il compilatore ha corretto un precedente Form 4 che aveva dichiarato erroneamente la proprietà post-transazione come 96.270 azioni; la correzione chiarisce la reale proprietà diretta.

Crinetics Pharmaceuticals (CRNX) persona reportante Dana Pizzuti ejecutó ejercicios de opciones y ventas en el mercado abierto el 10/01/2025. El Formulario 4 muestra un ejercicio de opción sobre acciones de 5,000 a un precio de ejercicio de $16.89, creando 5.000 acciones subyacentes. Ese mismo día, se vendieron 5.000 acciones en transacciones de mercado abierto bajo un plan de negociación Rule 10b5-1 con un precio medio ponderado por volumen de $41.81 (rango $41.34–$42.16). Tras las transacciones reportadas, la persona reportante poseía directamente 66,270 acciones. El presentador corrigió un Formulario 4 anterior que había indicado incorrectamente la propiedad posterior a la transacción como 96.270 acciones; la corrección aclara la verdadera propiedad directa.

Crinetics Pharmaceuticals (CRNX) 보고인 다나 피줄리이 옵션 행사와 공개시장 매도을 2025-10-01에 실행했습니다. 양식 4는 5,000주에 대한 주식 옵션 행사를 행사 가격 $16.89로 보여 주며 5,000주가 기초 주식으로 만들어집니다. 같은 날, 5,000주가 매도되었으며, 규칙 10b5-1 거래 계획에 따라 거래량 가중 평균가 $41.81로 이루어졌고 범위는 $41.34–$42.16입니다. 보고된 거래 이후 보고인은 직접적으로 66,270주를 보유했습니다. 보고인은 거래 후 소유를 96,270주로 잘못 기재한 이전 Form 4를 수정했으며, 수정은 진정한 직접 소유를 명확히 합니다.

Crinetics Pharmaceuticals (CRNX) personne rapportante Dana Pizzuti a exécuté des exercices d’options et des ventes sur le marché libre le 10/01/2025. Le Formulaire 4 affiche un exercice d’options d’actions sur 5 000 titres à un prix d’exercice de $16,89, créant 5 000 actions sous-jacentes. Le même jour, 5 000 actions ont été vendues dans des transactions sur le marché libre dans le cadre d’un plan de négociation Rule 10b5-1 à un prix moyen pondéré en fonction du volume de $41,81 (plage $41,34–$42,16). À la suite des transactions rapportées, la personne rapportante détenait directement 66 270 actions. Le déclarant a corrigé un Formulaire 4 antérieur qui avait indiqué à tort une propriété post-transaction de 96 270 actions; la correction précise la véritable propriété directe.

Crinetics Pharmaceuticals (CRNX) meldende Person Dana Pizzuti hat Optionsausübungen und Verkäufe am freien Markt am 10/01/2025 durchgeführt. Das Formular 4 zeigt eine Ausübung einer Aktienoption über 5.000 Stück zu einem Ausübungspreis von $16,89, wodurch 5.000 zugrunde liegende Aktien geschaffen werden. Am selben Tag wurden 5.000 Aktien in freien Markttransaktionen unter einem Handelsplan nach Regel 10b5-1 zu einem volumenindizierten Durchschnittspreis von $41,81 (Spanne $41,34–$42,16) verkauft. Nach den gemeldeten Transaktionen hielt die meldende Person direkt 66.270 Aktien. Der Einreicher korrigierte ein vorheriges Form 4, das den Besitz nach der Transaktion fälschlicherweise mit 96.270 Aktien angegeben hatte; die Korrektur klärt den tatsächlichen direkten Besitz auf.

SEC Form 4
FORM 4 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number: 3235-0287
Estimated average burden
hours per response: 0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
1. Name and Address of Reporting Person*
Pizzuti Dana

(Last) (First) (Middle)
C/O CRINETICS PHARMACEUTICALS, INC.
6055 LUSK BOULEVARD

(Street)
SAN DIEGO CA 92121

(City) (State) (Zip)
2. Issuer Name and Ticker or Trading Symbol
Crinetics Pharmaceuticals, Inc. [ CRNX ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
Director 10% Owner
X Officer (give title below) Other (specify below)
Chief Med and Dev Officer
3. Date of Earliest Transaction (Month/Day/Year)
10/01/2025
4. If Amendment, Date of Original Filed (Month/Day/Year)
6. Individual or Joint/Group Filing (Check Applicable Line)
X Form filed by One Reporting Person
Form filed by More than One Reporting Person
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 10/01/2025 M 5,000 A $16.89 71,270(1) D
Common Stock 10/01/2025 S(2) 5,000 D $41.81(3) 66,270 D
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year) 7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (Right to Buy) $16.89 10/01/2025 M 5,000 (4) 10/10/2032 Common Stock 5,000 $0 79,042 D
Explanation of Responses:
1. On September 4, 2025, the Reporting Person filed a Form 4 (the "Prior Form 4") which inadvertently reported that, following the transactions reported in the Prior Form 4, the Reporting Person directly owned 96,270 shares of the Issuer's common stock. In fact, the Reporting Person directly owned 66,270 shares of the Issuer's common stock following the transactions reported in the Prior Form 4.
2. The sale reported in this Form 4 was effected automatically pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on May 21, 2025.
3. The common stock was sold by the Reporting Person in open market transactions on the transaction date, with a volume weighted average sales price of $41.81 per share. The range of sales prices on the transaction date was $41.34 to $42.16 per share. Detailed information on the exact number of shares can be obtained from the Issuer upon request.
4. The option is exercisable as follows: 25% of the shares subject to the option vested on September 30, 2023, and the remaining number of shares subject to the option vest monthly thereafter in thirty-six equal monthly installments, subject to the Reporting Person's continued employment with the Issuer on each such vesting date.
Remarks:
/s/ Tobin Schilke, as attorney-in-fact 10/03/2025
** Signature of Reporting Person Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What insider transactions did CRNX reporting person Dana Pizzuti disclose?

On 10/01/2025 Ms. Pizzuti exercised a 5,000-share option at $16.89 and sold 5,000 shares in open-market trades at a VWAP of $41.81 under a Rule 10b5-1 plan.

How many shares does Dana Pizzuti own after the transactions in the Form 4?

The corrected Form 4 reports direct ownership of 66,270 shares following the transactions.

Why was a correction filed to a prior Form 4 for CRNX?

The prior Form 4 incorrectly reported post-transaction ownership as 96,270 shares; the current filing corrects that to 66,270 shares.

At what prices were the shares sold and what was the price range?

The shares were sold at a volume-weighted average price of $41.81 with a reported range of $41.34 to $42.16 on the transaction date.

Was the sale discretionary or pre-planned?

The sale was effected automatically pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on May 21, 2025.
Crinetics Pharmaceuticals

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Biotechnology
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