[Form 4/A] CASTLE BIOSCIENCES INC Amended Insider Trading Activity

Rhea-AI Filing Summary

Castle Biosciences (CSTL): Form 4/A amendment reports that the Chief Operating Officer sold 18,007 shares of common stock on 08/27/2025 at a weighted-average price of $21.69, with trades executed between $21.24 and $21.94. The amendment clarifies the sale was made by the Fritz Shorter Trust, not directly by the executive.

Following the sale, holdings were 52,924 shares held directly and 100,937 shares held indirectly through the Trust. The filing also notes prior transfers to the Trust of 96,322 shares on March 19, 2025 and 22,622 shares on August 22, 2025.

Insights

Securities compliance analyst

Administrative correction; insider holdings clarified.

This amended Form 4 corrects attribution and balances for an insider transaction. The COO’s 18,007-share sale on 08/27/2025 was executed via the Fritz Shorter Trust at a weighted-average of $21.69 within a $21.24–$21.94 range.

Post-transaction positions are 52,924 shares held directly and 100,937 indirectly via the Trust. Earlier transfers to the Trust on March 19, 2025 and August 22, 2025 are noted; cash-flow implications and market impact are not addressed in the excerpt.

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
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Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

1. Name and Address of Reporting Person^*

Oelschlager Kristen M

(Last) (First) (Middle)

C/O CASTLE BIOSCIENCES, INC.

505 S FRIENDSWOOD DRIVE, SUITE 401

(Street)

FRIENDSWOOD TX 77546

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
CASTLE BIOSCIENCES INC [ CSTL ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	Chief Operating Officer

3. Date of Earliest Transaction (Month/Day/Year)
08/27/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)
08/29/2025

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	08/27/2025		S		18,007	D	$21.69(1)	100,937(2)	I	The Fritz Shorter Trust(3)
Common Stock								52,924(2)	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. This transaction was executed in multiple trades at prices ranging from $21.24 to $21.94, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.

2. On August 29, 2025, the Reporting Person filed a Form 4 which inadvertently reported that shares were sold by the Reporting Person directly. In fact, as reported in this amendment, the shares were sold by the Fritz Shorter Trust (the "Trust"). The original Form 4 also mistakenly indicated the wrong number of shares held by the Reporting Person directly and indirectly through the Trust. In fact, following this sale, the Reporting Person held 52,924 shares of common stock directly and 100,937 shares of common stock indirectly through the Trust. In addition, following a reconciliation of the reporting person's holdings, it was determined that the balance previously reported was understated by 68 shares, and the holdings reported herein have been adjusted accordingly.

3. On March 19, 2025 and on August 22, 2025, the Reporting Person transferred 96,322 and 22,622 shares to the Trust. The transfer was not a change in beneficial ownership because the Reporting Person and her spouse are the trustees and sole beneficiaries of the Trust, the Trust is revocable and the Reporting Person has voting and investment power over the shares held by the Trust.

Remarks:

	/s/ Frank Stokes, Attorney-in-fact	11/04/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What did CSTL's COO report in the amended Form 4?

A sale of 18,007 shares on 08/27/2025 at a weighted-average price of $21.69, executed between $21.24–$21.94.

Who executed the CSTL share sale in the amendment?

The Fritz Shorter Trust, not the executive directly, as clarified in the amendment.

What are the COO’s holdings after the reported CSTL transaction?

52,924 shares held directly and 100,937 shares held indirectly through the Trust.

What prior share transfers to the Trust are disclosed for CSTL?

Transfers of 96,322 shares on March 19, 2025 and 22,622 shares on August 22, 2025.

What was the price range for the CSTL insider sale?

Trades occurred between $21.24 and $21.94; the weighted-average price was $21.69.

Why was the CSTL Form 4 amended?

To correct the selling party attribution to the Trust and to adjust the reported direct and indirect holdings.