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Castle Biosciences CEO sells 14,496 shares

The company's president and chief executive officer reported sales at a weighted-average $35.566 per share under a Rule 10b5-1 plan adopted June 2, 2026.

(Moderate)

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Form Type
4

Rhea-AI Filing Summary

Castle Biosciences Inc. CEO Derek J. Maetzold exercised 8,165 fully vested options at $2.39 per share for 8,165 common shares on October 5, 2026. Transactions included sales of 14,496 shares at a weighted-average $35.566 per share under a Rule 10b5-1 plan adopted June 2, 2026: 8,580 directly held by Maetzold, 3,198 held by The Maetzold Descendants 2020 Trust, and 2,718 by Derek Maetzold 2020 Irrevocable Trust. Those trusts reported 8,038 and 6,832 shares remaining, respectively.

Insider MAETZOLD DEREK J
Role Pres. & Chief Exec. Officer
Sold 14,496 shs ($516K)
Approx. gross sale proceeds $516K
Approx. exercise cost $20K
Type Security Shares Price Value
Exercise Stock option (right to buy) F1, F13 8,165 $0.00 $0.00
Exercise Common Stock F1 8,165 $2.39 $20K
Sale Common Stock F1, F2 8,580 $35.566 $305K
Sale Common Stock F1, F2, F3 3,198 $35.566 $114K
Sale Common Stock F1, F2, F4 2,718 $35.566 $97K
holding Common Stock F5 -- -- --
holding Common Stock F6 -- -- --
holding Common Stock F7 -- -- --
holding Common Stock F8 -- -- --
holding Common Stock F9 -- -- --
holding Common Stock F10 -- -- --
holding Common Stock F11 -- -- --
holding Common Stock F12 -- -- --
Holdings After Transaction: Stock option (right to buy) — 0 contracts (Direct); Common Stock — 21,064 shares (Direct); Common Stock — 8,038 shares (Indirect, By The Maetzold Descendants 2020 Trust); Common Stock — 6,832 shares (Indirect, By Derek Maetzold 2020 Irrevocable Trust); Common Stock — 11,256 shares (Indirect, By The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk); Common Stock — 11,256 shares (Indirect, By The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold); Common Stock — 11,256 shares (Indirect, By The Maetzold 2018 Remainder Trust FBO John Derek Maetzold); Common Stock — 11,256 shares (Indirect, By The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold); Common Stock — 11,963 shares (Indirect, By DJM Grantor Retained Annuity Trust No. 6); Common Stock — 27,862 shares (Indirect, By DJM Grantor Retained Annuity Trust No. 7); Common Stock — 40,935 shares (Indirect, By DJM Grantor Retained Annuity Trust No. 8); Common Stock — 23,216 shares (Indirect, DJM Grantor Retained Annuity Trust No. 9)
Footnotes (13)
  1. F1. These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on June 2, 2026.
  2. F2. This transaction was executed in multiple trades at prices ranging from $35.310 to $35.965, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.
  3. F3. Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries.
  4. F4. Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries.
  5. F5. Held by The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk of which the Reporting Person is the trustee and his child is the beneficiary.
  6. F6. Held by The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
  7. F7. Held by The Maetzold 2018 Remainder Trust FBO John Derek Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
  8. F8. Held by The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
  9. F9. Held by DJM Grantor Retained Annuity Trust No. 6 of which the Reporting Person is the trustee and the beneficiaries are The Maetzold 2018 Remainder Trust FBO John Derek Maetzold, The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk, The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold and The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold.
  10. F10. Held by DJM Grantor Retained Annuity Trust No. 7 of which the Reporting Person is the trustee and beneficiary.
  11. F11. Held by DJM Grantor Retained Annuity Trust No. 8 of which the Reporting Person is the trustee and beneficiary.
  12. F12. Held by DJM Grantor Retained Annuity Trust No. 9 of which the Reporting Person is the trustee and beneficiary.
  13. F13. The shares subject to the option are fully vested.
Options exercised 8,165 options October 5, 2026
Option exercise price $2.39 per share Exercise on October 5, 2026
Shares sold 14,496 shares October 5, 2026
Weighted-average sale price $35.566 per share Sales on October 5, 2026
Sale execution price range $35.310 to $35.965 per share Multiple trades; inclusive
Shares remaining in The Maetzold Descendants 2020 Trust 8,038 shares Following the reported sale
Shares remaining in Derek Maetzold 2020 Irrevocable Trust 6,832 shares Following the reported sale
Rule 10b5-1 plan regulatory
"pursuant to a Rule 10b5-1 plan adopted"
A Rule 10b5-1 plan is a prearranged, written schedule that lets corporate insiders buy or sell company stock at set times or amounts, even if they later learn material nonpublic information. Think of it like setting an automatic thermostat for trades: it creates a clear record that trades were planned in advance, reducing the risk of insider-trading accusations and helping investors trust that insider transactions are routine rather than based on secret information.
weighted-average sale price financial
"reflects the weighted-average sale price"
fully vested financial
"The shares subject to the option are fully vested"
exercise price financial
"at $2.3900"
The exercise price is the fixed amount at which you can buy or sell an asset, like a stock, when using an options contract. It matters because it helps determine whether exercising the option will be profitable or not, depending on the current market price. Think of it as the set price you agree on today to buy or sell later.
Grantor Retained Annuity Trust financial
"Held by DJM Grantor Retained Annuity Trust No. 6"
A grantor retained annuity trust (GRAT) is an estate-planning tool where the person who creates the trust transfers assets into it but receives fixed cash payments (an annuity) from the trust for a set number of years; whatever remains after that term passes to designated beneficiaries. It matters to investors because it can shift future appreciation of assets out of the creator’s taxable estate—like putting an asset into a timed vending machine that pays you fixed amounts while any extra value that grows inside the machine goes to heirs with reduced gift or estate tax consequences.

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

How many CSTL shares did the CEO sell, and at what price?

The reported sales totaled 14,496 shares at a weighted-average price of $35.566 per share on October 5, 2026. The sales occurred in multiple trades priced from $35.310 to $35.965, inclusive.

How many options did Castle Biosciences' CEO exercise?

Derek J. Maetzold exercised 8,165 fully vested options at $2.39 per share on October 5, 2026, acquiring 8,165 common shares. The reported option expiration date was May 9, 2028.

What trading prices made up the CSTL CEO's reported sale price?

The sales were executed in multiple trades at prices ranging from $35.310 to $35.965 per share, inclusive. The reported weighted-average sale price was $35.566 per share.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
X
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
MAETZOLD DEREK J

(Last)(First)(Middle)
C/O CASTLE BIOSCIENCES, INC.
1500 W. PARKWOOD AVE SUITE 400

(Street)
FRIENDSWOOD TEXAS 77546

(City)(State)(Zip)

UNITED STATES

(Country)
2. Issuer Name and Ticker or Trading Symbol
CASTLE BIOSCIENCES INC [ CSTL ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
XDirector10% Owner
XOfficer (give title below)Other (specify below)
Pres. & Chief Exec. Officer
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
10/05/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Common Stock10/05/2026M(1)8,165A$2.3929,644D
Common Stock10/05/2026S(1)8,580D$35.566(2)21,064D
Common Stock10/05/2026S(1)3,198D$35.566(2)8,038IBy The Maetzold Descendants 2020 Trust(3)
Common Stock10/05/2026S(1)2,718D$35.566(2)6,832IBy Derek Maetzold 2020 Irrevocable Trust(4)
Common Stock11,256IBy The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk(5)
Common Stock11,256IBy The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold(6)
Common Stock11,256IBy The Maetzold 2018 Remainder Trust FBO John Derek Maetzold(7)
Common Stock11,256IBy The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold(8)
Common Stock11,963IBy DJM Grantor Retained Annuity Trust No. 6(9)
Common Stock27,862IBy DJM Grantor Retained Annuity Trust No. 7(10)
Common Stock40,935IBy DJM Grantor Retained Annuity Trust No. 8(11)
Common Stock23,216IDJM Grantor Retained Annuity Trust No. 9(12)
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Stock option (right to buy)$2.3910/05/2026M(1)8,165 (13)05/09/2028Common Stock8,165$00D
Explanation of Responses:
1. These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on June 2, 2026.
2. This transaction was executed in multiple trades at prices ranging from $35.310 to $35.965, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.
3. Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries.
4. Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries.
5. Held by The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk of which the Reporting Person is the trustee and his child is the beneficiary.
6. Held by The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
7. Held by The Maetzold 2018 Remainder Trust FBO John Derek Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
8. Held by The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
9. Held by DJM Grantor Retained Annuity Trust No. 6 of which the Reporting Person is the trustee and the beneficiaries are The Maetzold 2018 Remainder Trust FBO John Derek Maetzold, The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk, The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold and The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold.
10. Held by DJM Grantor Retained Annuity Trust No. 7 of which the Reporting Person is the trustee and beneficiary.
11. Held by DJM Grantor Retained Annuity Trust No. 8 of which the Reporting Person is the trustee and beneficiary.
12. Held by DJM Grantor Retained Annuity Trust No. 9 of which the Reporting Person is the trustee and beneficiary.
13. The shares subject to the option are fully vested.
Remarks:
/s/ Frank Stokes, Attorney-in-fact10/07/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)

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